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Guideline: Insulin therapy for adult patients with type 2 diabetes mellitus

28 Oct, 2017 | 23:30h | UTC

Insulin therapy for adult patients with type 2 diabetes mellitus: a position statement of the Korean Diabetes Association, 2017 – Korean Journal of Internal Medicine (free PDF)

 


Guideline: Radiation Therapy for Oropharyngeal Squamous Cell Carcinoma

28 Oct, 2017 | 23:29h | UTC

Radiation Therapy for Oropharyngeal Squamous Cell Carcinoma: American Society of Clinical Oncology Endorsement of the American Society for Radiation Oncology Evidence-Based Clinical Practice Guideline (free)

 


Tue, October 24 – 10 Stories of The Day!

24 Oct, 2017 | 00:51h | UTC

 

1 – Guideline: Hepatitis B (chronic): diagnosis and management – National Institute for Health and Care Excellence (free)

 

2 – British Thoracic Society guidelines for the management of non-tuberculous mycobacterial pulmonary disease (NTM-PD) – Thorax (free)

 

3 – A toolkit for reducing repetitive routine blood draws in hospitals – Choosing Wisely Canada (free PDF)

News release: Toolkit: Pause the Draws (free)

 

4 – Policy Statement: Infection Prevention and Control in Pediatric Ambulatory Settings – American Academy of Pediatrics (free)

News release: Updated policy offers guidance on infection prevention, control in ambulatory settings (free)

Commentaries: Pediatrician’s New Germ-Control Advice: Bring Your Own Toys (10 articles per month are free) AND AAP: Hygiene, isolation protocols critical for infection control in pediatric office – Healio (free registration required)

 

5 – Clinical Report: Sexual and Reproductive Health Care Services in the Pediatric Setting – American Academy of Pediatrics (free)

News release: Pediatricians have key role in providing sexual, reproductive health care services (free)

 

6 – Incidence, Demographics, and Clinical Characteristics of Diabetes of the Exocrine Pancreas (Type 3c): A Retrospective Cohort Study – Diabetes Care (link to abstract – $ for full-text)

Commentary: Newly-identified third type of diabetes is being wrongly diagnosed as type 2 – The Conversation (free)

“Diabetes of the exocrine pancreas is frequently labeled type 2 diabetes but has worse glycemic control and a markedly greater requirement for insulin”.

 

7 – Concussion in adolescence and risk of multiple sclerosis – Annals of Neurology (link to abstract – $ for full-text)

Commentaries: Concussions in Teenagers Tied to Multiple Sclerosis Risk – The New York Times (10 articles per month are free) AND Teenage concussion linked to later risk of MS – Medical News Today (free)

 

8 – Multidisciplinary consensus on screening for, diagnosis and management of fetal growth restriction in the Netherlands – BMC Pregnancy and Childbirth (free)

 

9 – Clinical Management of Insomnia Disorder – JAMA (free)

“Cognitive Behavior Therapy for insomnia is recommended as 1st-line Tx; pharmacotherapy, if used, should be on a short-term basis” (RT @JAMAInternalMed see Tweet)

 

10 – Review: The challenge of Takotsubo syndrome: heterogeneity of clinical features – Swiss Medical Weekly (free)

 


Thu, October 26 – 10 Stories of The Day!

26 Oct, 2017 | 00:29h | UTC

 

1 – Modifiers of the effect of maternal multiple micronutrient supplementation on stillbirth, birth outcomes, and infant mortality: a meta-analysis of individual patient data from 17 randomised trials in low-income and middle-income countries – The Lancet Global Health (free)

Commentaries: Antenatal multiple micronutrient supplementation: benefits beyond iron-folic acid alone – The Lancet Global Health (free) AND Multiple micronutrient supplements to mothers improve survival for newborn girls – Harvard School of Public health (free)

Related systematic review: Multiple-micronutrient supplementation for women during pregnancy – Cochrane Library (free summary)

 

2 – Less dementia with oral anticoagulation in atrial fibrillation – European Heart Journal (free)

Commentaries: Blood-thinning drugs appear to protect against dementia in AF patients – OnMedica (free) AND Blood-thinning drugs ‘can reduce risk of dementia by up to 48%’ – The Guardian (free) AND Oral Anticoagulants Tied to Less Dementia in Patients with Atrial Fibrillation – Physician’s First Watch (free)

 

3 – Surgery for Drug-Resistant Epilepsy in Children – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: First test of anti-epilepsy surgeries in children shows dramatic benefit – Reuters (free) AND Surgery Cuts Seizures in Drug-Resistant Epilepsy – MedPage Today (free registration required)

 

4 – Guideline: Long-Acting Reversible Contraception: Implants and Intrauterine Devices – American College of Obstetricians and Gynecologists (free)

News release: LARC and Reproductive Choice (free)

Commentary: New Guidelines on LARC Released by ACOG – Medscape (free registration required)

 

5 – Review: The Practice and Implications of Finding Fluid During Point-of-Care Ultrasonography – JAMA Internal Medicine (free)

Related JAMA Video: Finding Fluid With Point-of-Care Ultrasonography (free)

 

6 – Depression and mortality in a longitudinal study: 1952–2011 – Canadian Medical Association Journal (free)

Commentaries: Depression strongly linked to higher long-term risk of early death for both women, men – ScienceDaily (free) AND Depression raises risk of early death – Medical News Today (free) AND Depression tied to shorter lifespan – Reuters (free)

 

7 – Is It Possible to Predict the Next Pandemic? – The Atlantic (free)

“Large initiatives are underway to pinpoint the next big viral threats—but some virologists believe the task is too hard”.

 

8 – Prognostic Effect and Longitudinal Hemodynamic Assessment of Borderline Pulmonary Hypertension – JAMA Internal Medicine (free)

Commentary: Borderline Pulmonary Hypertension Tied to Mortality Risk – MedPage Today (free registration required)

 

9 – Here’s Why Vaccines Are So Crucial – National Geographic Magazine (free) (via @filiamd)

 

10 – Aerosol delivery during invasive mechanical ventilation: a systematic review – Critical Care (free)

 


Wed, October 25 – 10 Stories of The Day!

25 Oct, 2017 | 00:19h | UTC

 

1 – Statin use and risk of developing diabetes: results from the Diabetes Prevention Program – BMJ Open Diabetes Research & Care (free)

Commentaries: Statins increase the risk of developing diabetes in at-risk people – Medical News Today (free) AND Statin use link to heightened type 2 diabetes risk in some people – OnMedica (free)

 

2 – Synopsis of the 2017 U.S. Department of Veterans Affairs/U.S. Department of Defense Clinical Practice Guideline: Management of Type 2 Diabetes Mellitus – Annals of Internal Medicine (free)

Related 2017 Guidelines: Type 2 diabetes in adults: management – NICE Guideline (free) AND Pharmacologic Therapy for Type 2 Diabetes: Synopsis of the 2017 American Diabetes Association Standards of Medical Care in Diabetes (free) AND Oral Pharmacologic Treatment of Type 2 Diabetes Mellitus: A Clinical Practice Guideline Update From the American College of Physicians (free)

 

3 – Global prevalence of injecting drug use and sociodemographic characteristics and prevalence of HIV, HBV, and HCV in people who inject drugs: a multistage systematic review – The Lancet Global Health (free)

Related article: Global, regional, and country-level coverage of interventions to prevent and manage HIV and hepatitis C among people who inject drugs: a systematic review – The Lancet Global Health (free)

Commentary: New research highlights worldwide risk of HIV, Hepatitis C epidemics – University of New South Wales, via ScienceDaily (free)

 

4 – Effect of Robotic-Assisted vs Conventional Laparoscopic Surgery on Risk of Conversion to Open Laparotomy Among Patients Undergoing Resection for Rectal Cancer: The ROLARR Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Related Study: Association of Robotic-Assisted vs Laparoscopic Radical Nephrectomy With Perioperative Outcomes and Health Care Costs, 2003 to 2015 – JAMA (free)

Commentaries: Comparison of Outcomes for Robotic-Assisted vs Laparoscopic Surgical Procedures – The JAMA Network (free) AND Robotic docs can boost surgery time and cost – Science News (free) AND Robot-assisted surgery for kidney removal associated with longer operating times, higher cost – Stanford Medicine (free) AND Robotic-assisted surgery: more expensive, but not always more effective – Reuters (free)

 

5 – Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms – Scientific Reports (free)

Recommended Commentary: Magic mushrooms: Some reporters buy magical notion of ‘reset’ button for depression – Health News Review (free)

Other Commentaries: Magic mushrooms ‘reboot’ brain in depressed people – study – The Guardian (free) AND Magic mushrooms can ‘reset’ depressed brain – BBC News (free)

 

6 – Cardiovascular Health in African Americans: A Scientific Statement From the American Heart Association – Circulation (free PDF)

News releases: African Americans live shorter lives due to heart disease and stroke – AHA / ASA Newsroom (free) AND New report raises concerns about the cardiovascular health of African-Americans – AHA News (free)

Commentaries: Blacks Face Higher Mortality from Heart Disease, Stroke – Cardiobrief (free) AND Heart health disparities take toll on African-Americans – Reuters (free)

 

7 – A baby with a disease gene or no baby at all: Genetic testing of embryos creates an ethical morass – STAT (free)

 

8 – Richard Lehman’s journal review, 23 October 2017 – The BMJ Opinion (free)

Richard Lehman’s weekly review of medical journals.

 

9 – Protection of the house against Chagas disease, dengue, leishmaniasis, and lymphatic filariasis: a systematic review – The Lancet Infectious Diseases (free registration required)

 

10 – Head position after acute stroke does not affect disability outcomes – NIHR Signal (free)

Original article: Cluster-Randomized, Crossover Trial of Head Positioning in Acute Stroke – The New England Journal of Medicine (link to abstract – $ for full-text)

 


How Hospitals Are Using Patient-Reported Outcomes to Improve Care

24 Oct, 2017 | 16:37h | UTC

How Hospitals Are Using Patient-Reported Outcomes to Improve Care – Harvard Business Review (a few articles per month are free)

 


Research: Upright versus lying down position in second stage of labour in nulliparous women with low dose epidural

23 Oct, 2017 | 20:47h | UTC

Upright versus lying down position in second stage of labour in nulliparous women with low dose epidural: BUMPES randomised controlled trial – The BMJ (free)

Commentaries: During Labor, Lie Down – The New York Times (10 articles per month are free) AND Normal birth more likely when lying down in late stages, post epidural – OnMedica (free)

 


Is gene editing ethical?

23 Oct, 2017 | 20:45h | UTC

Is gene editing ethical? – Medical News Today (free)

Related: Embryo Gene-Editing Experiment Reignites Ethical Debate – Scientific American (free) AND U.S. scientists edit genome of human embryo, but cast doubt on possibility of ‘designer babies’ – STAT (free)

Related Position Statement: Human Germline Genome Editing – American Society of Human Genetics (free) AND Commentary: 11 Organizations Urge Cautious but Proactive Approach to Gene Editing

 


Report: Global causes of blindness and distance vision impairment

23 Oct, 2017 | 20:48h | UTC

Global causes of blindness and distance vision impairment 1990–2020: a systematic review and meta-analysis – The Lancet Global Health (free)

Invited commentary: Global causes of vision loss in 2015: are we on track to achieve the Vision 2020 target? (free)

Related study: Magnitude, temporal trends, and projections of the global prevalence of blindness and distance and near vision impairment: a systematic review and meta-analysis – The Lancet Global Health (free) AND Invited Commentary: Universal eye health: are we getting closer? (free)

 


Review: Thrombophilia Testing and Venous Thrombosis

23 Oct, 2017 | 20:46h | UTC

Summary with 10 key points to remember: Thrombophilia Testing and Venous Thrombosis – American College of Cardiology, Latest in Cardiology (free)

See also: Thrombophilia Testing and Venous Thrombosis – NEJM Resident 360 (free)

Original article: Thrombophilia Testing and Venous Thrombosis – New England Journal of Medicine (link to abstract – $ for full-text)

 


Research: Azithromycin, levofloxacin or rifaximin for travelers diarrhea?

23 Oct, 2017 | 20:45h | UTC

Trial Evaluating Ambulatory Therapy of Travelers’ Diarrhea (TrEAT TD) Study: A Randomized Controlled Trial Comparing 3 Single-Dose Antibiotic Regimens With Loperamide – Clinical Infectious Diseases (link to abstract – $ for full-text)

Commentary: Azithromycin, levofloxacin, rifaximin all effective for travelers diarrhea – Healio (free registration required)

 


Review: Weight Gain in Women at Midlife

23 Oct, 2017 | 20:39h | UTC

Weight Gain in Women at Midlife: A Concise Review of the Pathophysiology and Strategies for Management – Mayo Clinic Proceedings (free)

Commentary: Docs Call Attention to Women Piling on Pounds in Midlife – Medscape (free registration required)

 


Report: the economic costs of lung disease and the cost effectiveness of policy and service interventions

23 Oct, 2017 | 20:43h | UTC

Literature review: the economic costs of lung disease and the cost effectiveness of policy and service interventions – British Lung Foundation and British Thoracic Society (free PDF)

News release: New report identifies the most cost effective NHS activities and programmes to improve lung health – British Thoracic Society (free)

Source: Most cost effective treatments for lung disease identified – The BMJ News ($)

“The most cost effective treatments are: patient education and self management for asthma; stop smoking support for chronic obstructive pulmonary disease (COPD); vaccination programmes for pneumonia; and awareness campaigns for lung cancer” (from The BMJ).

 


Placing wet gauze on babies’ tummies speeds up urine collection

23 Oct, 2017 | 20:37h | UTC

Placing wet gauze on babies’ tummies speeds up urine collection – NIHR Signal (free)

Original article: Faster clean catch urine collection (Quick-Wee method) from infants: randomised controlled trial – The BMJ (free)

 


Research: Walking in Relation to Mortality

23 Oct, 2017 | 20:40h | UTC

Walking in Relation to Mortality in a Large Prospective Cohort of Older U.S. Adults – American Journal of Preventive Medicine (free)

Commentaries: Regular Walking, Even if Minimal, Tied to Lower Death Risk – Medscape (free registration required) AND Study finds even regular walking can lower mortality risk – UPI (free)

 


UNICEF: Levels & Trends in Child Mortality

21 Oct, 2017 | 18:25h | UTC

Levels & Trends in Child Mortality – UNICEF (free PDF)

News release: Levels and Trends in Child Mortality (free)

Commentaries: 7,000 newborns die every day, despite steady decrease in under-five mortality, new report says – The World Bank (free) AND New child mortality estimates show that 15,000 children died every day in 2016 – The World Bank (free) AND ‘Unconscionable’: 7,000 babies die daily despite record low for child mortality – The Guardian (free)

 


Carefully managed antibiotic use could halve antibiotic-resistant infections

23 Oct, 2017 | 20:38h | UTC

Carefully managed antibiotic use could halve antibiotic-resistant infections – NIHR Signal (free)

Original article: Effect of antibiotic stewardship on the incidence of infection and colonisation with antibiotic-resistant bacteria and Clostridium difficile infection: a systematic review and meta-analysis – The Lancet Infectious Diseases (link to abstract – $ for full-text)

 


Report: The Lancet Commission on pollution and health

21 Oct, 2017 | 18:24h | UTC

The Lancet Commission on pollution and health (Report, Executive Summary, Video, Audio and Comments – free registration required)

Commentaries: Report: Pollution Kills 3 Times More than AIDS, TB And Malaria Combined – NPR (free) AND Pollution linked to one in six deaths – BBC (free)

 


Guidelines for the Diagnosis and Management of Infectious Diarrhea

21 Oct, 2017 | 18:23h | UTC

2017 Infectious Diseases Society of America Clinical Practice Guidelines for the Diagnosis and Management of Infectious Diarrhea (free)

Commentary: New diarrhea guidelines stress implications of molecular tests – CIDRAP (free)

 


Mon, October 23 – 10 Stories of The Day!

23 Oct, 2017 | 00:28h | UTC

 

1 – Global causes of blindness and distance vision impairment 1990–2020: a systematic review and meta-analysis – The Lancet Global Health (free)

Invited commentary: Global causes of vision loss in 2015: are we on track to achieve the Vision 2020 target? (free)

Related study: Magnitude, temporal trends, and projections of the global prevalence of blindness and distance and near vision impairment: a systematic review and meta-analysis – The Lancet Global Health (free) AND Invited Commentary: Universal eye health: are we getting closer? (free)

 

2 – Upright versus lying down position in second stage of labour in nulliparous women with low dose epidural: BUMPES randomised controlled trial – The BMJ (free)

Commentaries: During Labor, Lie Down – The New York Times (10 articles per month are free) AND Normal birth more likely when lying down in late stages, post epidural – OnMedica (free)

 

3 – Summary with 10 key points to remember: Thrombophilia Testing and Venous Thrombosis – American College of Cardiology, Latest in Cardiology (free)

See also: Thrombophilia Testing and Venous Thrombosis – NEJM Resident 360 (free)

Original article: Thrombophilia Testing and Venous Thrombosis – New England Journal of Medicine (link to abstract – $ for full-text)

 

4 – Is gene editing ethical? – Medical News Today (free)

Related: Embryo Gene-Editing Experiment Reignites Ethical Debate – Scientific American (free) AND U.S. scientists edit genome of human embryo, but cast doubt on possibility of ‘designer babies’ – STAT (free)

Related Position Statement: Human Germline Genome Editing – American Society of Human Genetics (free) AND Commentary: 11 Organizations Urge Cautious but Proactive Approach to Gene Editing (free)

 

5 – Trial Evaluating Ambulatory Therapy of Travelers’ Diarrhea (TrEAT TD) Study: A Randomized Controlled Trial Comparing 3 Single-Dose Antibiotic Regimens With Loperamide – Clinical Infectious Diseases (link to abstract – $ for full-text)

Commentary: Azithromycin, levofloxacin, rifaximin all effective for travelers diarrhea – Healio (free registration required)

 

6 – Literature review: the economic costs of lung disease and the cost effectiveness of policy and service interventions – British Lung Foundation and British Thoracic Society (free PDF)

News release: New report identifies the most cost effective NHS activities and programmes to improve lung health – British Thoracic Society (free)

Source: Most cost effective treatments for lung disease identified – The BMJ News ($)

“The most cost effective treatments are: patient education and self management for asthma; stop smoking support for chronic obstructive pulmonary disease (COPD); vaccination programmes for pneumonia; and awareness campaigns for lung cancer” (from The BMJ).

 

7 – Walking in Relation to Mortality in a Large Prospective Cohort of Older U.S. Adults – American Journal of Preventive Medicine (free)

Commentaries: Regular Walking, Even if Minimal, Tied to Lower Death Risk – Medscape (free registration required) AND Study finds even regular walking can lower mortality risk – UPI (free)

 

8 – Weight Gain in Women at Midlife: A Concise Review of the Pathophysiology and Strategies for Management – Mayo Clinic Proceedings (free)

Commentary: Docs Call Attention to Women Piling on Pounds in Midlife – Medscape (free registration required)

 

9 – Carefully managed antibiotic use could halve antibiotic-resistant infections – NIHR Signal (free)

Original article: Effect of antibiotic stewardship on the incidence of infection and colonisation with antibiotic-resistant bacteria and Clostridium difficile infection: a systematic review and meta-analysis – The Lancet Infectious Diseases (link to abstract – $ for full-text)

 

10 – Placing wet gauze on babies’ tummies speeds up urine collection – NIHR Signal (free)

Original article: Faster clean catch urine collection (Quick-Wee method) from infants: randomised controlled trial – The BMJ (free)

 


Guideline: Right heart dysfunction and failure in heart failure with preserved ejection fraction

21 Oct, 2017 | 18:22h | UTC

Right heart dysfunction and failure in heart failure with preserved ejection fraction: mechanisms and management. Position statement on behalf of the Heart Failure Association of the European Society of Cardiology (free)

 


Research: A Highly Pathogenic Avian H7N9 Influenza Virus

21 Oct, 2017 | 18:16h | UTC

A Highly Pathogenic Avian H7N9 Influenza Virus Isolated from A Human Is Lethal in Some Ferrets Infected via Respiratory Droplets – Cell Host Microbe (free)

Commentaries: H7N9 study finds virus poised to become more lethal, resistant to treatment – CIDRAP (free) AND H7N9 influenza is both lethal and transmissible in animal model for flu – University of Wisconsin–Madison (free) AND Will the World’s Most Worrying Flu Virus Go Pandemic? – The Atlantic (free)

 


Meta-analysis: High-flow oxygen via nasal cannulae in patients with acute hypoxemic respiratory failure

21 Oct, 2017 | 18:20h | UTC

High-flow oxygen via nasal cannulae in patients with acute hypoxemic respiratory failure: a systematic review and meta-analysis – Systematic Reviews (free)

“In patients with acute hypoxemic respiratory failure HFNC was not associated with a difference in mortality compared to Noninvasive ventilation or standard oxygen”

 


Research: Colchicine Therapy and Plaque Stabilization in Patients With Acute Coronary Syndrome

21 Oct, 2017 | 18:19h | UTC

Imaging Studies Offer New Insights Into Inflammation In CV Disease – Cardiobrief (free)

Original article: Colchicine Therapy and Plaque Stabilization in Patients With Acute Coronary Syndrome – Journal of The American College of Cardiology (link to abstract – $ for full-text)

“Preliminary evidence that colchicine may reduce coronary plaque”.

 


Research: Elevated blood pressure and risk of mitral regurgitation

21 Oct, 2017 | 18:21h | UTC

Elevated blood pressure and risk of mitral regurgitation: A longitudinal cohort study of 5.5 million United Kingdom adults – PLOS Medicine (free)

Commentaries: High Blood Pressure Is a Risk Factor For Mitral Regurgitation – Medical Research (free) AND High Blood Pressure May Raise Mitral Regurgitation Risk – TCTMD (free) AND Inevitable or preventable? High blood pressure linked to mitral regurgitation – Cardiovascular Business (free)

 


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