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Research: Aspirin Lowers Risk of Death for Patients with Diabetes, Heart Failure
16 Mar, 2018 | 03:15h | UTC#ACC18 – Aspirin Lowers Risk of Death for Patients with Diabetes, Heart Failure – American College of Cardiology (free) AND Aspirin Linked to Lower Mortality in Diabetes With Heart Failure – Medscape (free registration required) AND ACC 2018: Aspirin Lowers Risk of Death in Patients With Diabetes and Heart Failure – PracticeUpdate (free registration required)
Research: Low-level lead exposure and mortality in US adults
16 Mar, 2018 | 02:43h | UTCCommentaries: Lead and the heart: an ancient metal’s contribution to modern disease – The Lancet Public Health (free) AND Lead exposure may be linked to 412,000 premature US deaths yearly, study says – The Guardian (free) AND Lead and CDV deaths in US adults – Science Media Centre (free) AND Expert reaction to lead and CVD deaths in the US – Science Media Centre (free)
Guidelines for Aneurysmal Subarachnoid Hemorrhage
16 Mar, 2018 | 02:41h | UTC
Research: Health Care Spending in the United States and Other High-Income Countries
16 Mar, 2018 | 02:41h | UTCHealth Care Spending in the United States and Other High-Income Countries – JAMA (free article, editorials, author interview and video summary)
Commentaries: Why Is U.S. Health Care So Expensive? Some of the Reasons You’ve Heard Turn Out to Be Myths – The New York Times (10 articles per month are free) AND Huge cost of US healthcare driven by drug prices and salaries – The Guardian (free) AND Healthcare: It’s The Prices, Stupid. Isn’t It? – Forbes (free) AND Physician Salaries, Drug Prices Drive High US Health Costs – Medscape (free registration required)
Guideline Summary: Peripheral Arterial Diseases
16 Mar, 2018 | 02:42h | UTCThe 2017 ESC Guidelines on PADs: what’s new? – European Heart Journal (free) AND The ‘Ten Commandments’ of 2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases – European Heart Journal (free)
Original Guideline: 2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS) (free)
Meta-Analysis: Dialysis Modality Survival Comparison
16 Mar, 2018 | 02:40h | UTCEditorial: Dialysis Modality Survival Comparison: Time to End the Debate, It’s a Tie – American Journal of Kidney Diseases (free)
Related commentary: PD or HD: Which Road Do We Take? – AJKD Blog (free)
Original article: Comparison of Patient Survival Between Hemodialysis and Peritoneal Dialysis Among Patients Eligible for Both Modalities – American Journal of Kidney Diseases (link to abstract – $ for full-text)
Source: Hemodialysis vs. Peritoneal Dialysis for End-Stage Renal Disease – NEJM Journal Watch ($)
Research: 6-month versus 12-month or longer dual antiplatelet therapy after percutaneous coronary intervention in patients with acute coronary syndrome
16 Mar, 2018 | 02:29h | UTC#ACC18 – 6-month versus 12-month or longer dual antiplatelet therapy after percutaneous coronary intervention in patients with acute coronary syndrome (SMART-DATE): a randomised, open-label, non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Commentaries: SMART-DATE: Myocardial Infarction Risk Higher with Six-Month Versus Twelve-Month DAPT – American College of Cardiology (free) AND Too Soon for 6-Month DAPT, Say SMART-DATE Investigators, Despite Positive Trial – TCTMD (free)
Related Guidelines: 2018 Canadian Cardiovascular Society/Canadian Association of Interventional Cardiology Focused Update of the Guidelines for the Use of Antiplatelet Therapy (free) AND 2017 European Society of Cardiology focused update on dual antiplatelet therapy in coronary artery disease (free) AND 2016 ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease (free)
A Visual introduction to the basic concepts of probability theory
16 Mar, 2018 | 02:39h | UTCVery interesting resource: A Visual introduction to the basic concepts of probability theory – Seeing Theory (free) (via @CochraneUK see Tweet)
Review: Pulmonary arterial hypertension
16 Mar, 2018 | 02:38h | UTCState of The Art Review: Pulmonary arterial hypertension: pathogenesis and clinical management – The BMJ (free for a limited period)
Related Guidelines: Pharmacologic Therapy for Pulmonary Arterial Hypertension in Adults – CHEST Guideline and Expert Panel Report (free) AND 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension (free)
Review: Effects of stress on the development and progression of cardiovascular disease
16 Mar, 2018 | 02:26h | UTCEffects of stress on the development and progression of cardiovascular disease – Nature Reviews Cardiology (free PDF for a limited period) (via @Abraham_RMI)
Chronic kidney disease and arrhythmias
16 Mar, 2018 | 02:27h | UTC
Guideline: Evaluation and Treatment of Hirsutism in Premenopausal Women
16 Mar, 2018 | 02:28h | UTCKey Points: Evaluation and Treatment of Hirsutism in Premenopausal Women – JAMA Clinical Guidelines Synopsis (free for a limited period)
Meta-Analysis: Digital Rectal Examination for Prostate Cancer Screening in Primary Care
16 Mar, 2018 | 02:26h | UTCCommentaries: New analysis recommends against using digital rectal exam in primary care – American Academy of Family Physicians, vie EurekAlert (free) AND Little Evidence Supports Use of Digital Rectal Exam – Medscape (free registration required) AND Digital Rectal Exams for Routine Prostate Screening Discouraged – NEJM Physician’s First Watch (free)
Research: Endovascular treatment for acute ischaemic stroke in routine clinical practice
16 Mar, 2018 | 02:25h | UTCRelated guideline: 2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association / American Stroke Association (free PDF) AND Summary for ED-relevant care: 2018 AHA/ASA Ischemic Stroke Updates – emDocs (free)
“In routine clinical practice, endovascular treatment for patients with acute ischemic stroke is at least as effective and safe as in the setting of a randomized controlled trial”.
Research: Sustained Physical Activity, Not Weight Loss, Associated With Improved Survival in Coronary Heart Disease
16 Mar, 2018 | 02:24h | UTCSustained Physical Activity, Not Weight Loss, Associated With Improved Survival in Coronary Heart Disease – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentary: For CHD Patients, Physical Activity More Meaningful Than Weight Changes Over Time – TCTMD (free)
Research: Colonoscopy and Colorectal Cancer Mortality
16 Mar, 2018 | 02:23h | UTCColonoscopy and Colorectal Cancer Mortality in the Veterans Affairs Health Care System: A Case–Control Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Colonoscopy significantly reduces mortality from colorectal cancer in Veterans Affairs study – 2 Minute Medicine (free) AND Colonoscopy Significantly Reduces CRC Deaths – Medscape (free registration required)
Research: BNP in the emergency department
16 Mar, 2018 | 02:22h | UTCN-Terminal Pro–B-Type Natriuretic Peptide in the Emergency Department – Journal of the Americana College of Cardiology (link to abstract – $ for full-text)
Commentary: NT-proBNP cutpoints validated for diagnosing and ruling out heart failure in the ED – ACP Hospitalist (free)
Related review: BNP in the emergency department: The evidence – First10EM (free)
“In acutely dyspneic patients seen in the ED setting, age-stratified NT-proBNP cutpoints may aid in the diagnosis of acute HF. An NT-proBNP <300 pg/ml strongly excludes the presence of acute HF”.
Research: Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout
16 Mar, 2018 | 02:14h | UTCCommentaries: Gout Drug Febuxostat Linked to More CV Deaths Without Uptick in CV Events: CARES Trial – TCTMD (free) AND CARES: Increased Risk of Death With Febuxostat in Patients With Gout and CV Disease – American College of Cardiology (free) AND
Research: Antifungal Combinations for Treatment of Cryptococcal Meningitis in Africa
16 Mar, 2018 | 02:12h | UTCCommentary: Combo Tx Offers New Hope for Cryptococcal Meningitis – MedPage Today (free registration required)
More Deaths, Strokes Seen with Perioperative Beta Blocker
16 Mar, 2018 | 02:13h | UTCRelated (just published) systematic review: Perioperative beta-blockers for preventing surgery-related mortality and morbidity – Cochrane Library (free)
Guideline: Management of Multi-Casualty Incidents in Mountain Rescue
16 Mar, 2018 | 02:12h | UTCSource: Critical Care Reviews Newsletter
Research: Pregnancy Outcomes after ZIKV Infection
16 Mar, 2018 | 02:11h | UTCEditorial: Recognizing the Global Impact of Zika Virus Infection during Pregnancy (free)
Quick Take Video Summary: Pregnancy Outcomes after Zika (free)
Commentaries: Study: 7% risk of birth defects in Zika pregnancies – CIDRAP (free) AND Birth defect rate pegged at 7 percent for babies born to Zika-infected women – Reuters (free)
Research: Calcium and vitamin D supplementation and increased risk of serrated polyps
16 Mar, 2018 | 02:10h | UTCCalcium and vitamin D supplementation and increased risk of serrated polyps: results from a randomised clinical trial – Gut (link to abstract – $ for full-text)
Commentaries: Calcium and vitamin D supplements may raise risk of polyps – MedicalNewsToday (free) AND Calcium Supplements Up Risk for Precancerous Serrated Polyps – Medscape (free registration required)
See related meta-analysis of RCT showing calcium and vitamin D don’t prevent bone fractures
Statement: ADA Deeply Concerned About New Guidance from ACP Regarding Blood Glucose Targets
16 Mar, 2018 | 02:10h | UTCSee original guideline and commentary: ACP Guideline: Hemoglobin A1c Targets for Glycemic Control in Type 2 Diabetes
Like It Or Not, Personal Health Technology Is Getting Smarter
16 Mar, 2018 | 02:08h | UTCLike It Or Not, Personal Health Technology Is Getting Smarter – NPR (free)
“Nice article about wearables related issues, such as medicalization of the healthy, privacy loss, low adherence, uncertain reliability of measurements and uncertain health benefits”. (via @RasoiniR see Tweet)