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“IBM has big plans for how its Watson artificial intelligence software could change the medical industry. But a number of hospitals have ended their experiments with the platform, arguing that it doesn’t help diagnose or treat diseases.”

The Illness Is Bad Enough. The Hospital May Be Even Worse

11 Aug, 2018 | 02:04h | UTC

The Illness Is Bad Enough. The Hospital May Be Even Worse – The New York Times (10 articles per month are free)

“The elderly are particularly vulnerable to “post-hospital syndrome,” some experts believe, and that may be why so many patients return.”

Bias in Medical Research: A Glossary of Common Research Biases

11 Aug, 2018 | 02:05h | UTC

Bias in medical research: A glossary of common research biases – First10Em (free) (via @pash22)

WHO: Ebola Outbreak in the Democratic Republic of Congo

11 Aug, 2018 | 02:03h | UTC

Disease Outbreak News: Ebola virus disease – Democratic Republic of the Congo – World Health Organization (free)

Study: Quantifying Excess Deaths Related to Heatwaves Under Climate Change Scenarios

11 Aug, 2018 | 02:04h | UTC

Quantifying excess deaths related to heatwaves under climate change scenarios: A multicountry time series modelling study – PLOS Medicine (free)

Commentaries: Heatwave deaths will rise steadily by 2080 as globe warms up – Monash University, via ScienceDaily (free) AND Heatwave deaths likely to rise steadily by 2080 without appropriate climate and health policies – London School of Hygiene & Tropical Medicine (free)

Related Lancet Editorial: Heatwaves and health (free)

Related Report: Lancet Countdown: Traking Progress on Health and Climate Change (free report, commentaries, infographics, video and other resources)

Randomized Trial: Peer-Delivered Self-Management Programs in Mental Health

11 Aug, 2018 | 02:01h | UTC

Peer-supported self-management for people discharged from a mental health crisis team: a randomised controlled trial – The Lancet (free)

Commentaries: Peer-delivered self-management programmes in mental health – The Lancet (free) AND After the crisis: self-management and peer-support – The Mental Elf (free) AND Peer Support Helps Reduce Mental Crisis Readmissions – MedPage Today (free registration required)

Systematic Review: Colloids vs Crystalloids for Fluid Resuscitation in Critically Ill People

11 Aug, 2018 | 02:02h | UTC

Colloids versus crystalloids for fluid resuscitation in critically ill people – Cochrane Library (link to abstract – $ for full-text)

Summary: Colloids or crystalloids for fluid replacement in critically people – Cochrane Library (free)

“Using starches, dextrans, albumin or FFP (moderate-certainty evidence), or gelatins (low-certainty evidence), versus crystalloids probably makes little or no difference to mortality. Starches probably slightly increase the need for blood transfusion and RRT (moderate-certainty evidence), and albumin or FFP may make little or no difference to the need for renal replacement therapy (low-certainty evidence)”.

Fri, August 10 – 10 Stories of The Day!

10 Aug, 2018 | 02:01h | UTC

1 – Dietary Diversity: Implications for Obesity Prevention in Adult Populations: A Science Advisory From the American Heart Association – Circulation (free PDF)

News Release: A diverse diet may not be the healthiest one (free)

Commentary: Diet Recommendations for Obesity Prevention: Time to Ditch Diversity (free)

Top Ten Things to Know: Dietary Diversity: Implications for Obesity Prevention in Adult Populations (free PDF)

2 – Opioid prescribing decreases after learning of a patient’s fatal overdose – Science (free for a limited period)

Commentary: Notification of patient overdose deaths reduces clinician opioid prescriptions – NIH News Releases (free) AND Clinicians were told their patient had died of an overdose. Then opioid prescribing dropped – STAT (free)

3 – Comparative efficacy and tolerability of medications for attention-deficit hyperactivity disorder in children, adolescents, and adults: a systematic review and network meta-analysis – The Lancet Psychiatry (free)

Commentaries: Refining treatment choices for ADHD – The Lancet Psychiatry (free) AND ADHD medications: Of all available drugs, methylphenidate should be first option for short-term treatment in children – ScienceDaily (free) AND Analysis of ADHD Drugs: Use Methylphenidate in Kids, Amphetamines in Adults – Physician’s First Watch (free)

4 – Viewpoint: Clinical Practice Guidelines: What’s Next? – JAMA (free for a limited period)

5 – Urinary sodium excretion, blood pressure, cardiovascular disease, and mortality: a community-level prospective epidemiological cohort study – The Lancet (link to abstract – $ for full-text)

Commentary: Lancet Paper Adds To Evidence That Reducing Salt To Very Low Levels May Be Dangerous – CardioBrief (free)

Related Report: Salt intake and Cardiovascular Disease (free report and commentaries)

6 – Are the “Best Buys” for Alcohol Control Still Valid? An Update on the Comparative Cost-Effectiveness of Alcohol Control Strategies at the Global Level – Journal of Studies on Alcohol and Drugs (free)

Commentary: Higher alcohol taxes are cost-effective in reducing alcohol harms – ScienceDaily (free)

Related: To improve global health, tax the things that are killing us – Financial Times (free policies, articles and commentaries) AND Policy lessons from health taxes (free research and commentaries)

7 – Nonsurgical Treatments for Urinary Incontinence in Women: A Systematic Review Update – Agency for Healthcare Research and Quality (free)

See also: Full Report (free PDF)

8 – Scaled deployment of Wolbachia to protect the community from Aedes transmitted arboviruses – Gates Open Research (free)

Commentary: Dengue rates plummet in Australian city after release of modified mosquitoes – Nature News (free)

9 – Disease Outbreak News: Ebola virus disease – Democratic Republic of the Congo – World Health Organization (free)

10 – Association of Endometrial Cancer Risk With Postmenopausal Bleeding in Women: A Systematic Review and Meta-analysis – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: How common is endometrial cancer in women with postmenopausal bleeding? – eCancer News (free) AND Postmenopausal Bleeding: Reliable Sign of Endometrial Cancer – Medscape (free registration required)

Mon, August 6 – 10 Stories of The Day!

6 Aug, 2018 | 00:05h | UTC

1 – Delirium in adult cancer patients: ESMO Clinical Practice Guidelines – Annals of Oncology (free)

2 – Comparison of Clinical Outcomes Among Patients With Atrial Fibrillation or Atrial Flutter Stratified by CHA₂DS₂-VASc Score – JAMA Network Open (free)

Commentaries: Ischemic Stroke Risk Scoring May Not Be Accurate for Patients with Atrial Flutter – TCTMD (free) AND Don’t Group Afib, Atrial Flutter Together in Evaluating Stroke Risk – MedPage Today (free registration required)

3 – The Surviving Sepsis Campaign: A Rush to Judgment – NEJM Journal Watch (free)

Original Guideline: The Surviving Sepsis Campaign Bundle: 2018 update – Intensive Care Medicine (free)

Related Opinion: Petition to retire the surviving sepsis campaign guidelines – PulmCrit (free)

4 – Playing Doctor with Watson: Medical Applications Expose Current Limits of AI – Spiegel (free) (via @EricTopol)

5 – Bias in medical research: A glossary of common research biases – First10Em (free) (via @pash22)

6 – The Illness Is Bad Enough. The Hospital May Be Even Worse – The New York Times (10 articles per month are free)

“The elderly are particularly vulnerable to “post-hospital syndrome,” some experts believe, and that may be why so many patients return.”

7 – Quantifying excess deaths related to heatwaves under climate change scenarios: A multicountry time series modelling study – PLOS Medicine (free)

Commentaries: Heatwave deaths will rise steadily by 2080 as globe warms up – Monash University, via ScienceDaily (free) AND Heatwave deaths likely to rise steadily by 2080 without appropriate climate and health policies – London School of Hygiene & Tropical Medicine (free)

Related Lancet Editorial: Heatwaves and health (free)

Related Report: Lancet Countdown: Traking Progress on Health and Climate Change (free report, commentaries, infographics, video and other resources)

8 – Disease Outbreak News: Ebola virus disease – Democratic Republic of the Congo – World Health Organization (free)

9 – Colloids versus crystalloids for fluid resuscitation in critically ill people – Cochrane Library (link to abstract – $ for full-text)

Summary: Colloids or crystalloids for fluid replacement in critically people – Cochrane Library (free)

10 – Peer-supported self-management for people discharged from a mental health crisis team: a randomised controlled trial – The Lancet (free)

Commentaries: Peer-delivered self-management programmes in mental health – The Lancet (free) AND After the crisis: self-management and peer-support – The Mental Elf (free) AND Peer Support Helps Reduce Mental Crisis Readmissions – MedPage Today (free registration required)

Thu, August 9 – 10 Stories of The Day!

9 Aug, 2018 | 01:34h | UTC

1 – Practice guideline update recommendations summary: Disorders of consciousness – American Academy of Neurology (free PDF)

Commentaries: New Guideline Released for Managing Vegetative and Minimally Conscious States – American Academy of Neurology, via NewsWise (free) AND Groups Issue New Disorders of Consciousness Guidelines – MedPage Today (free registration required)

2 – Labor Induction versus Expectant Management in Low-Risk Nulliparous Women – New England Journal of Medicine (link to abstract – $ for full-text)

Quick Take Video Summary: Labor Induction versus Expectant Management in Low-Risk Women (free)

Commentaries: Induced labor at 39 weeks may reduce likelihood of C-section, NIH study suggests – NIH News Releases (free) AND Pregnancy Debate Revisited: To Induce Labor, Or Not? – NPR (free)

3 – Vitamin D Supplementation in Pregnancy and Lactation and Infant Growth – New England Journal of Medicine (free)

Commentary: Maternal Vitamin D Supplementation Doesn’t Improve Infant Growth – Physician’s First Watch (free)

4 – Outcomes of Cardiac Screening in Adolescent Soccer Players – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Footballer heart death risk ‘underestimated’ – BBC (free) AND No Easy Answers on Best Heart Check-Up for Young Athletes – Associated Press, via NYT (free)

5 – Would technology enabled remote consulting save time and add value in primary care? – The BMJ Opinion (free)

“Would remote consulting save time and add value in primary care? Rising multimorbidity makes the evaluation of potentially time saving technologies ever more necessary” (via @bmj_latest see Tweet)

6 – Treatment for Bipolar Disorder in Adults: A Systematic Review – Agency for Healthcare Research and Quality (free)

See also: Full Report (free PDF) AND Evidence Summary (free PDF)

7 – WHO MERS Global Summary and Assessment of Risk – World Health Organization (free PDF)

Commentary: WHO highlights ongoing hospital MERS outbreak threat – CIDRAP (free)

8 – Perspective: Addressing Barriers to Inclusion of Pregnant Women in Clinical Trials – JAMA (free for a limited period)

9 – Publication bias: The answer to your research question may be sitting in somebody’s file drawer – Students 4 Best Evidence (free)

10 – Association between physical exercise and mental health in 1·2 million individuals in the USA between 2011 and 2015: a cross-sectional study – The Lancet Psychiatry (link to abstract – $ for full-text)

Commentaries: Expert reaction to physical activity linked to improved mental health – Science Media Centre (free) AND Regular exercise ‘best for mental health’ – BBC (free) AND Exercise is good for your body and your mind, study says – CNN (free)

Guideline: Management of Heart Failure 2018

3 Aug, 2018 | 11:51h | UTC

National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand: Australian clinical guidelines for the management of heart failure 2018 – The Medical Journal of Australia (free for 10 days)

Wed, August 8 – 10 Stories of The Day!

8 Aug, 2018 | 02:21h | UTC

1 – Screening for Atrial Fibrillation With Electrocardiography: US Preventive Services Task Force Recommendation Statement – JAMA (free)

Editorials: Screening for Atrial Fibrillation Comes With Many Snags (free for a limited period) AND Electrocardiography Screening for Atrial Fibrillation: We Can Do Better (free for a limited period)

Author Interview: USPSTF Recommendation: Screening for Atrial Fibrillation With Electrocardiography (free audio)

“The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for atrial fibrillation with ECG. (I statement)”

2 – Mortality effects of timing alternatives for hip fracture surgery – Canadian Medical Association Journal (free)

Commentaries: Lower death rate when senior hip fractures are repaired quickly – Reuters (free) AND Delayed surgery for hip fractures cause of preventable deaths, study finds – The Globe and Mail (free) AND The sun should not set twice before hip fracture repair – CMAJ, via ScienceDaily (free)

3 – Update: Interim Guidance for Preconception Counseling and Prevention of Sexual Transmission of Zika Virus for Men with Possible Zika Virus Exposure — United States, August 2018 – CDC, MMWR (free)

Commentaries: 1 in 7 kids exposed to Zika in utero suffers defects, delays – CIDRAP (free) AND 1 in 7 babies exposed to Zika in the womb have health problems, CDC reports – STAT (free) AND One in 7 babies prenatally exposed to Zika has health problems, CDC says – CNN (free)

4 – Corticosteroid use and intensive care unit-acquired weakness: a systematic review and meta-analysis – Critical Care (free)

5 – The use of viscoelastic haemostatic assays in the management of major bleeding: A British Society for Haematology Guideline – British Journal of Haematology (free)

Source: Critical Care Reviews Newsletter

6 – Perspective: Workplace Wellness Programs Don’t Work Well. Why Some Studies Show Otherwise. – The New York Times (10 articles per month are free)

7 – Last Month in Oncology with Dr. Bishal Gyawali: July 2018 – eCancer News (free)

8 – Cardiotoxicity and Cardiac Monitoring Among Chemotherapy-Treated Breast Cancer Patients – JACC: Cardiovascular Imaging (link to abstract – $ for full-text)

Commentaries: Prioritize cardiac monitoring for high-risk breast cancer patients, study suggests – ACP Internist (free) AND Cardiac monitoring may benefit high-risk breast cancer patients against heart failure – Cardiovascular Business (free) AND After Cardiotoxic Chemo, Less Than Half of Women With Breast Cancer Get Recommended Monitoring – TCTMD (free) AND Study Shows Importance of Cardiac Monitoring in High-Risk Breast Cancer Patients – American College of Cardiology (free)

9 – Special Issue: Roles of Physicians in Healthy Dying- AMA Journal of Ethics (free articles)

“What the roles of clinicians and patients should be in defining what constitutes a quality dying experience and good care of dying people has received less attention than issues like euthanasia and assisted death. Which parts of dying, if any, should be medicalized and why? What do patients and clinicians need to know about dying and why? The August 2018 issue of the AMA Journal of Ethics explores these and other questions.”

10 – Twelve-Month Outcomes After Transplant of Hepatitis C–Infected Kidneys Into Uninfected Recipients: A Single-Group Trial – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Patients who accepted infected kidneys cured of hepatitis C – STAT (free) AND Good Outcomes for HCV-Negative Recipients of HCV Kidneys – Renal & Urology News (free)