Archives
Study: Immediate Hypersensitivity to Contrast Agents
16 Aug, 2018 | 23:13h | UTCImmediate Hypersensitivity to Contrast Agents: The French 5-year CIRTACI Study – EclinicalMedicine (free)
Guideline: Pediatric CAR T-Cell Therapy
16 Aug, 2018 | 23:16h | UTCCommentary: Guidelines for Pediatric CAR T-Cell Therapy Developed – The ASCO Post (free)
Perspective: Managing De-implementation in General Practice
16 Aug, 2018 | 23:11h | UTCManaging de-implementation in general practice – Royal Australian College of General Practitioners (free)
Study: Nuts as a Replacement for Carbohydrates in the Diabetic Diet
16 Aug, 2018 | 23:10h | UTC
Study: Factors in Men’s Choice of Active Surveillance for Low-risk Prostate Cancer
16 Aug, 2018 | 23:12h | UTCFactors in men’s choice of active surveillance for low-risk prostate cancer – NIHR Signal (free)
Original Article: Factors Influencing Men’s Choice of and Adherence to Active Surveillance for Low-risk Prostate Cancer: A Mixed-method Systematic Review – European Urology (link to abstract – $ for full-text)
Study: Sex and BMI Alter the Benefits and Risks of Sulfonylureas and Thiazolidinediones in Type 2 Diabetes
16 Aug, 2018 | 23:09h | UTCSex and BMI Alter the Benefits and Risks of Sulfonylureas and Thiazolidinediones in Type 2 Diabetes: A Framework for Evaluating Stratification Using Routine Clinical and Individual Trial Data – Diabetes Care (link to abstract – $ for full-text)
Commentary: Doctors should use gender and body mass to personalise diabetes care, study says – The Irish News (free)
Source: The BMJ Research News ($)
Study: Use of Oximetry to Determine Need for Adenotonsillectomy for Sleep-Disordered Breathing
16 Aug, 2018 | 23:11h | UTCUse of Oximetry to Determine Need for Adenotonsillectomy for Sleep-Disordered Breathing – Pediatrics (link to abstract – $ for full-text)
Commentary: Oximetry Results Help Determine Need for Adenotonsillectomy – Medscape (free registration required)
Review: Genetic Testing and Counseling After Sudden Cardiac Death
16 Aug, 2018 | 23:06h | UTC
Things We Do for No Reason: Blood Cultures for Uncomplicated Skin and Soft Tissue Infections in Children
16 Aug, 2018 | 23:08h | UTC
Guideline: Management of Adrenocortical Carcinoma in Adults
16 Aug, 2018 | 23:08h | UTCEuropean Society of Endocrinology Clinical Practice Guidelines on the Management of Adrenocortical Carcinoma in Adults, in collaboration with the European Network for the Study of Adrenal Tumors – European Journal of Endocrinology (free PDF)
Wed, August 15 – 10 Stories of The Day!
15 Aug, 2018 | 02:32h | UTC
1 – State of the Art Review: Overdiagnosis in primary care: framing the problem and finding solutions – The BMJ (free for two weeks)
2 – Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations – Nature Genetics (link to abstract – $ for full-text)
Commentaries: Researchers predict risk for common deadly diseases from millions of genetic variants – Broad Institute of MIT and Harvard, ScienceDaily (free) AND Clues to Your Health Are Hidden at 6.6 Million Spots in Your DNA – The New York Times (10 articles per month are free) AND Multi-gene test may find risk for heart disease and more – Associated Press (free) AND A Harvard Scientist Thinks He Has a Gene Test for Heart Attack Risk. He Wants to Give It Away Free – Forbes (free)
3 – Fixed Low-Dose Triple Combination Antihypertensive Medication vs Usual Care for Blood Pressure Control in Patients With Mild to Moderate Hypertension in Sri Lanka: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Video Summary: Fixed-Dose Combination Pill for Hypertension Treatment in Sri Lanka (free)
Commentaries: Three-in-one pill lowers blood pressure significantly, study say – UPI (free) AND Innovative triple pill significantly lowers blood pressure, study finds – George Institute for Global Health, via EurekAlert (free)
4 – Richard Smith: The polypill and the long journey to major impact – The BMJ Opinion (free)
Related Reviews: Strengths and Limitations of Using the Polypill in Cardiovascular Prevention – Current Cardiology Reports (free) AND The polypill approach – An innovative strategy to improve cardiovascular health in Europe – BMC Pharmacology and Toxicology (free)
6 – Opinion: Lessons for physicians from ‘The Bleeding Edge’: If you see something, say something – STAT (free)
“…physicians must act decisively when they identify the rare outlier in their midst. To do anything less would risk our credibility. Worse still, it could risk the lives of the people we took an oath not to harm.”
7 – Yoga, Depression, & Clinical Trial Critique 101 – Hilda Bastian, in Absolutely Maybe Blog (free)
“5 steps to unpack a randomized trial!” (via @hildabast, see Tweet)
8 – DRC Ebola cases surpass earlier outbreak total, virus infects 4 more health workers – CIDRAP (free)
Related: DRC may provide model for containing future Ebola outbreaks – The Conversation (free)
9 – Book: Diabetes in America, 3rd Edition – National Institutes of Health (free chapters)
News Release: New NIH reference book is one-stop resource for diabetes medical information – National Institutes of Health (free)
10 – Treatments for women with gestational diabetes mellitus: an overview of Cochrane systematic reviews – Cochrane Library (free)
Thu, August 16 – 10 Stories of The Day!
16 Aug, 2018 | 00:15h | UTC
1 – Risk Factors, Mortality, and Cardiovascular Outcomes in Patients with Type 2 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: In Type 2 Diabetes, Five Risk Factor Targets Keep MI, Stroke, and Death in Check – TCTMD (free) AND How People With Type 2 Diabetes Can Lower Their Risk of Health Problems – TIME (free) AND T2D, Without Other Risks, Not Tied to Excess Mortality – MedPage Today (free registration required)
Commentary: Brain scan checklist set to boost care for stroke survivors – University of Edinburgh, via EurekAlert (free)
Commentaries: Daily Chest X-Rays Still Overused in Mechanically Ventilated Patients – MedicalResearch.com (free) AND Routine daily CXRs for ventilated patients: de-adoption is lagging – Univadis (free registration required) AND Chest x-rays overused on ventilation patients despite ACR guideline – HealthImaging (free)
4 – Editorial: Making diagnostic tests as essential as medicines – BMJ Global Health (free)
Related: Report: First-ever WHO List of Essential Diagnostic Tests (free report and news release) AND The WHO Essential Diagnostic List: A Tool for the Future (free commentaries)
5 – How Unpaywall is transforming open science – Nature News (free)
Related: Unlocking paywalled research papers (legally) (free commentaries) AND Half of papers searched for online are free to read (free)
We have been using the Unpaywall Extension for a while, and it is indeed a handy tool to find free versions (entirely legal) of paywalled articles.
6 – Long-Term Prognosis of Patients With Takotsubo Syndrome – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Long-Term Prognosis of Takotsubo Syndrome – American College of Cardiology (free) AND How deadly is Takotsubo syndrome? It depends on the trigger – Cardiovascular Business (free)
Related: International Expert Consensus Document on Takotsubo Syndrome (free)
7 – Perspective: Medical students are skipping class in droves — and making lectures increasingly obsolete – STAT (free)
Related: WHO chief calls for end to fighting in Congo to halt Ebola spread – The Guardian (free) AND Ebola cases mounting in DRC as region prepares for more – CIDRAP (free)
9 – Association Between Traumatic Brain Injury and Risk of Suicide – JAMA (link to abstract – $ for full-text)
Commentaries: Traumatic brain injury tied to increased risk of suicide – Reuters (free) AND Risk of Suicide Increases After TBI, Study Finds – Psychiatric News Alert (free) AND Expert reaction to traumatic brain injury and suicide – Science Media Centre (free)
10 – Amisulpride and olanzapine followed by open-label treatment with clozapine in first-episode schizophrenia and schizophreniform disorder (OPTiMiSE): a three-phase switching study – The Lancet Psychiatry (link to abstract – $ for full-text)
Commentaries: Switching Anti-Psychotic Medications Doesn’t Improve Outcomes in First-Episode Schizophrenia Patients – Mount Sinai (free) AND No Benefit of Switching Antipsychotics in Early Schizophrenia – Medscape (free registration required) AND No Gain with Antipsych Meds Switch in Schizophrenia – MedPage Today (free registration required)
Tue, August 14 – 10 Stories of The Day!
14 Aug, 2018 | 01:03h | UTC
1 – Clinically applicable deep learning for diagnosis and referral in retinal disease – Nature Medicine (free for a limited period)
Commentaries: Opening the ‘black box,’ Google DeepMind AI system diagnoses eye diseases and shows its work – STAT (free) AND Artificial intelligence tool ‘as good as experts’ at detecting eye problems – The Guardian (free)
2 – Automated deep-neural-network surveillance of cranial images for acute neurologic events – Nature Medicine (free for a limited period)
Commentaries: Artificial Intelligence Platform Screens for Acute Neurological Illnesses at Mount Sinai – Mount Sinai Health System, via NewsWise (free) AND AI diagnoses neurological diseases on CT in 1.2 seconds – Health Imaging (free) AND New AI system can screen for neurological illnesses in seconds – UPI (free)
Commentaries: WPSI says screen all women annually for urinary incontinence – American College of Physicians, via EurekAlert (free)
5 – American Academy of Family Physicians: Twenty Things Physicians and Patients Should Question (free)
Commentary: Choosing Wisely: New Practices to Avoid in Family Medicine – NEJM Journal Watch (free)
See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Commentaries: Should we screen women for abdominal aortic aneurysm? – The Lancet (free) AND Cost-Effectiveness of Screening Women for AAA – American College of Cardiology (free) AND Women Likely Not Good Targets for AAA Screening, Study Suggests – TCTMD (free)
Commentaries: Prevalence of Substandard and Falsified Essential Medicines: Still an Incomplete Picture – JAMA Network Open (free) AND New Study Finds Fake, Low-Quality Medicines Prevalent in the Developing World – University of North Carolina at Chapel Hill, via R&D (free)
8 – Evaluating Shared Decision Making for Lung Cancer Screening – JAMA Internal Medicine (free for a limited period)
Editorial: Failing Grade for Shared Decision Making for Lung Cancer Screening (free for a limited period)
Author Interview: Evaluating Shared Decision Making for Lung Cancer Screening (free audio)
Commentaries: Doctors may not explain pros, cons of lung cancer screening – Reuters (free) AND Shared Decision-Making Flops for Lung Ca Screening – MedPage Today (free registration required)
9 – Perspective: Surrogate End Points Ain’t all that Bad – The Health Care Blog (free) (via @RogueRad)
10 – Excess mortality and cardiovascular disease in young adults with type 1 diabetes in relation to age at onset: a nationwide, register-based cohort study – The Lancet (link to abstract – $ for full-text)
Commentaries: Early type 1 diabetes shortens women’s lives by 18 years – University of Gothenburg, via ScienceDaily (free) AND Early age type 1 diabetes linked to shorter life expectancy than later age diagnosis – OnMedica (free)
Mon, August 13 – 10 Stories of The Day!
13 Aug, 2018 | 00:05h | UTC
1 – Corticosteroid therapy for sepsis: a clinical practice guideline – The BMJ (free)
2 – Outbreaks: Behind the headlines – World Health Organization (free)
Commentaries: Algorithm IDs Patients at Risk of Post-MI Events – MedPage Today (free registration required) AND Risk Model Helps Predict CV Events 1 Year After Acute MI – Medscape (free registration required)
4 – Analysis: Renaming low risk conditions labelled as cancer – The BMJ (free for a limited period)
Commentaries: Is it time to remove the cancer label from low-risk conditions? – The Conversation (free) AND Doctors should avoid saying ‘cancer’ for minor lesions – study – The Guardian (free) Drop ‘cancer’ label to protect patients from over-treatment, researchers say – The Sidney Morning Herald (free)
5 – Review: Dos and Don’ts in the Management of Cirrhosis: A View from the 21st Century – American Journal of Gastroenterology (via @Abraham_RMI)
Related Study: Association of Multivitamin and Mineral Supplementation and Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis – Circulation: Cardiovascular Quality and Outcomes (free) AND Editorial: Multivitamins Do Not Reduce Cardiovascular Disease and Mortality and Should Not Be Taken for This Purpose: How Do We Know That? (free)
“Unless you have a clinically identified deficiency, the research tells us there is little reason to consume supplements.”
7 – Tick- and Mosquito-Borne Diseases Are Increasing Dramatically – Scientific American (free)
Related: CDC Report: U.S Trends in Vector-borne Diseases (link to report and commentaries)
8 – Infographic: High burden, low budget: non-communicable diseases in low- and middle-income countries – Institute for Health Metrics and Evaluation (free) (via @equitylist)
News release and visual abstract: KI article shows the doubling incidence, prevalence and mortality of CKD – International Society of Nephrology (free)
Commentary: Global Burden of Kidney Disease on the Rise, Unequally Distributed – Medscape (free registration required)
Study: Opioid Prescribing Decreases After Learning of a Patient’s Fatal Overdose
11 Aug, 2018 | 03:25h | UTCOpioid prescribing decreases after learning of a patient’s fatal overdose – Science (free for a limited period)
Commentary: Notification of patient overdose deaths reduces clinician opioid prescriptions – NIH News Releases (free) AND Clinicians were told their patient had died of an overdose. Then opioid prescribing dropped – STAT (free)
Meta-Analysis: Treatment Choices for ADHD
11 Aug, 2018 | 03:23h | UTCCommentaries: Refining treatment choices for ADHD – The Lancet Psychiatry (free) AND ADHD medications: Of all available drugs, methylphenidate should be first option for short-term treatment in children – ScienceDaily (free) AND Analysis of ADHD Drugs: Use Methylphenidate in Kids, Amphetamines in Adults – Physician’s First Watch (free)
Related: Cochrane Review: Adverse Events of Methylphenidate for ADHD in Children and Adolescents (link to abstract and free summary) AND Short Review: Stimulants for ADHD in children (free) AND Opinion: Drug treatment of ADHD – tenuous scientific basis (free)
Clinical Practice Guidelines: What’s Next?
11 Aug, 2018 | 03:22h | UTCClinical Practice Guidelines: What’s Next? – JAMA (free for a limited period)
AHA Scientific Advisory: A Diverse Diet May Not Be the Healthiest One
11 Aug, 2018 | 03:26h | UTCNews Release: A diverse diet may not be the healthiest one (free)
Commentary: Diet Recommendations for Obesity Prevention: Time to Ditch Diversity (free)
Top Ten Things to Know: Dietary Diversity: Implications for Obesity Prevention in Adult Populations (free PDF)
Cohort Study: Urinary Sodium Excretion, Blood Pressure, Cardiovascular Disease, and Mortality
11 Aug, 2018 | 03:21h | UTCUrinary sodium excretion, blood pressure, cardiovascular disease, and mortality: a community-level prospective epidemiological cohort study – The Lancet (link to abstract – $ for full-text)
Commentary: Lancet Paper Adds To Evidence That Reducing Salt To Very Low Levels May Be Dangerous – CardioBrief (free)
Related Report: Salt intake and Cardiovascular Disease (free report and commentaries)
Study: Comparative Cost-Effectiveness of Alcohol Control Strategies at the Global Level
11 Aug, 2018 | 03:20h | UTCCommentary: Higher alcohol taxes are cost-effective in reducing alcohol harms – ScienceDaily (free)
Related: To improve global health, tax the things that are killing us – Financial Times (free policies, articles and commentaries) AND Policy lessons from health taxes (free research and commentaries)
Study: Modified Mosquitoes to Reduce Dengue Rates
11 Aug, 2018 | 03:18h | UTCCommentary: Dengue rates plummet in Australian city after release of modified mosquitoes – Nature News (free)
WHO: Update on Ebola Outbreak
11 Aug, 2018 | 03:16h | UTCDisease Outbreak News: Ebola virus disease – Democratic Republic of the Congo – World Health Organization (free)
Related: DRC probes more suspected Ebola cases, rules out 3 – CIDRAP (free) AND War zone complicates roll-out of Ebola vaccine in latest outbreak – Nature News (free)
Systematic Review: Nonsurgical Treatments for Urinary Incontinence in Women
11 Aug, 2018 | 03:19h | UTCSee also: Full Report (free PDF)
Meta-Analysis: Postmenopausal Bleeding and Endometrial Cancer Risk
11 Aug, 2018 | 03:15h | UTCAssociation of Endometrial Cancer Risk With Postmenopausal Bleeding in Women: A Systematic Review and Meta-analysis – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: How common is endometrial cancer in women with postmenopausal bleeding? – eCancer News (free) AND Postmenopausal Bleeding: Reliable Sign of Endometrial Cancer – Medscape (free registration required)
AAN Guideline: Disorders of Consciousness
11 Aug, 2018 | 03:14h | UTCRelated: Ethical, palliative, and policy considerations in disorders of consciousness – Neurology (free PDF) AND Comprehensive systematic review update summary: Disorders of consciousness – Neurology (free PDF)
Commentaries: New Guideline Released for Managing Vegetative and Minimally Conscious States – American Academy of Neurology, via NewsWise (free) AND Groups Issue New Disorders of Consciousness Guidelines – MedPage Today (free registration required)