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Wed, September 19 – 10 Stories of The Day!

19 Sep, 2018 | 02:19h | UTC

 

1 – Global Tuberculosis Report 2018 – World Health Organization (free PDF)

Commentaries: UN tuberculosis summit ‘historic opportunity’ to put response ‘back on track’: new WHO report – UN News (free) AND WHO TB Report Sets Stage for Historic U.N.TB Meeting – American Thoracic Society (free) AND WHO report warns efforts to end TB are falling short – CIDRAP (free)

 

2 – Positive Pressure Ventilation in the Cardiac Intensive Care Unit – Journal of the American College of Cardiology (free for a limited period) (via @Abraham_RMI)

 

3 – Can Artificial Intelligence Reliably Report Chest X-Rays?: Radiologist Validation of an Algorithm trained on 1.2 Million X-Rays – Cornell University Library (free PDF)

News Release: Qure.ai’s qXR Algorithm can ID Abnormal Chest X-rays With Unprecedented Accuracy (free)

Commentary: AI algorithm IDs abnormal chest x-rays with 90% accuracy – Health Imaging (free) AND AI startup trains algorithm with 1.2M chest x-rays, confirms its accuracy – Radiology Business (free)

 

4 – Classification and mutation prediction from non–small cell lung cancer histopathology images using deep learning – Nature Medicine (link to abstract – $ for full-text)

Commentaries: Artificial intelligence can determine lung cancer type – eCancer News (free) AND Google AI Tool Identifies a Tumor’s Mutations From An Image – WIRED (free)

 

5 – Behavioral Weight Loss Interventions to Prevent Obesity-Related Morbidity and Mortality in Adults: US Preventive Services Task Force Recommendation Statement – JAMA (free)

Author Interview: USPSTF Recommendation: Behavioral Interventions to Prevent Adult Obesity-Related Outcomes (free)

Editorials: Weight Management in Adults With Obesity: What Is a Primary Care Clinician to Do? (free for a limited period) AND Treating Obesity—Moving From Recommendation to Implementation (free for a limited period)

Commentaries: Intensive lifestyle changes best for people with BMI above 30, task force says – UPI (free) AND Doctors Should Send Obese Patients To Diet Counseling, Panel Says. But Many Don’t – NPR (free)

 

6 – Efficacy and Safety of Short‐term Dual Antiplatelet Therapy (≤ 6 Months) after Percutaneous Coronary Intervention for Acute Coronary Syndrome; A Systematic Review and Meta‐analysis of Randomized Controlled Trials – Clinical Cardiology (free PDF)

 

7 – Daily Fasting Improves Health and Survival in Male Mice Independent of Diet Composition and Calories – Cell Metabolism (link to abstract and infographic – $ for full-text)

Commentaries: Fasting increases health and lifespan in male mice – NIH Research Matters (free) AND Study: Mice healthier, live longer with increased daily fasting times – UPI (free) AND Study: Daily Fasting Improves Health and Longevity in Male Mice – Sci News (free)

 

8 – Higher Whole-Grain Intake Is Associated with Lower Risk of Type 2 Diabetes among Middle-Aged Men and Women: The Danish Diet, Cancer, and Health Cohort – The Journal of Nutrition (link to abstract – $ for full-text)

Commentary: What you need to know about claims that whole grains can prevent diabetes – Health News Review (free)

 

9 – Association of Hospital Participation in a Medicare Bundled Payment Program With Volume and Case Mix of Lower Extremity Joint Replacement Episodes – JAMA (link to abstract – $ for full-text)

Commentaries: Can Paying for a Health Problem as a Whole, Not Piece by Piece, Save Medicare Money? – The New York Times (10 articles per month are free) AND Medicare’s Bundled Payment Program–Does it Change Hospital Volume or Case Mix? – MedicalResearch.com (free) AND One of Obamacare’s big experiments to lower costs is working surprisingly well – VOX (free)

 

10 – Prevalence of Burnout Among Physicians: A Systematic Review – JAMA (link to abstract – $ for full-text)

Commentaries: Doctors Today May Be Miserable, But Are They ‘Burnt Out’? – NPR (free) AND Physician burnout taking center stage – Reuters (free) AND Burnout Found to Be Common Among U.S. Resident Physicians – Psychiatric News Alert (free)

Related: Why Physician Burnout Is Endemic, and How Health Care Must Respond – NEJM Catalyst (free) AND Counting the costs: U.S. hospitals feeling the pain of physician burnout – Reuters (free) AND To Care Is Human — Collectively Confronting the Clinician-Burnout Crisis – New England Journal of Medicine (free) AND Beyond Burnout — Redesigning Care to Restore Meaning and Sanity for Physicians (free) AND The Burnout Crisis in American Medicine – The Atlantic (free) AND To Combat Physician Burnout and Improve Care, Fix the Electronic Health Record (free commentaries)

 


Tue, September 18 – 10 Stories of The Day!

18 Sep, 2018 | 00:01h | UTC

 

1 – Implementing Optimal Team-Based Care to Reduce Clinician Burnout – National Academy of Medicine (free)

Commentaries: Optimal team-based health care is associated with improved patient outcomes and physician well-being – ACP Newsroom (free) AND New Review Shows Team-Based Care May Reduce Physician Burnout – Medscape (free registration required)

 

2 – Diagnosis and management of Aspergillus diseases: executive summary of the 2017 ESCMID-ECMM-ERS guideline – Clinical Microbiology and Infection (free)

Related: Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America (free)

Source: Critical Care Reviews Newsletter

 

3 – Viewpoint: Probiotic Safety—No Guarantees – JAMA Internal Medicine (free for a limited period)

Related: Probiotics: Does the Evidence Match the Hype? (free articles and commentaries) AND Systematic Review: Harms Reporting in Trials with Probiotics (link to abstract and commentaries)

 

4 – Zackary Berger’s journal reviews, 17 September 2018 – The BMJ Opinion (free)

Zackary Berger reviews the latest research from the top medical journals.

 

5 – Opinion: Medicine’s Financial Contamination – The New York Times (10 articles per month are free)

 

6 – Infant Walker–Related Injuries in the United States – Pediatrics (free)

News Release: Study: Infant walker injuries support AAP’s call for a ban (free)

Commentaries: As Injuries Continue, Doctors Renew Call For Ban On Infant Walkers – NPR (free) AND Injuries associated with infant walkers still sending children to the emergency department – Nationwide Children’s Hospital (free)

 

7 – Ensuring Comprehensive Care and Support for Transgender and Gender-Diverse Children and Adolescents – Pediatrics (free)

News release: AAP Policy Statement Urges Support and Care of Transgender and Gender-Diverse Children and Adolescents (free) AND New Guidance for Care of Transgender Children, Teenagers – Medscape (free registration required)

 

8 – Let’s stop the burning and the bleeding at Cochrane—there’s too much at stake – The BMJ Opinion (free)

Related: Evidence-based medicine group in turmoil after expulsion of co-founder – Science (free) AND Trish Greenhalgh: The Cochrane Collaboration—what crisis? – The BMJ Opinion (free) AND Cochrane – A sinking ship? – BMJ EBM Spotlight (free) AND Turmoil erupts over expulsion of member from leading evidence-based medicine group – STAT (free)

See also: Statement from Cochrane’s Governing Board (free)

 

9 – Treatments of Primary Basal Cell Carcinoma of the Skin: A Systematic Review and Network Meta-analysis – Annals of Internal Medicine (free)

 

10 – Development of a New Classification System for Idiopathic Inflammatory Myopathies Based on Clinical Manifestations and Myositis-Specific Autoantibodies – JAMA Neurology (link to abstract – $ for full-text)

Commentary: New Classification of Idiopathic Inflammatory Myopathies – RheumNow (free)

 


Report: Variation in Childhood Diarrheal Morbidity and Mortality in Africa

20 Sep, 2018 | 15:32h | UTC

Variation in Childhood Diarrheal Morbidity and Mortality in Africa, 2000–2015 – New England Journal of Medicine (free)

News Release: Discomfort or death? New study maps hot spots of child mortality from diarrhea across Africa – Institute for Health Metrics and Evaluation (free)

Quick Take Video Summary: Variation in Childhood Diarrheal Morbidity and Mortality in Africa (free)

 


Cohort Study: Elevated Blood Pressure and Risk of Aortic Valve Disease

14 Sep, 2018 | 02:30h | UTC

Elevated blood pressure and risk of aortic valve disease: a cohort analysis of 5.4 million UK adults – European Heart Journal (free)

Commentary: Elevated blood pressure is linked to increased risk of aortic valve disease – European Society of Cardiology (free)

 


AHA Guideline: Resistant Hypertension

14 Sep, 2018 | 02:31h | UTC

Resistant Hypertension: Detection, Evaluation, and Management: A Scientific Statement From the American Heart Association – Hypertension (free PDF)

News Release: Diagnosing and treating resistant hypertension (free)

Commentaries: Tackling Resistant Hypertension – Opportunities and Challenges (free) AND Heart Group Updates Guidelines on Resistant Hypertension – Physician’s First Watch (free)

Top Ten Things to Know: Resistant Hypertension: Detection, Evaluation, and Management (free PDF)

 


Mon, September 17 – 10 Stories of The Day!

17 Sep, 2018 | 00:09h | UTC

 

1 – Effect of Aspirin on All-Cause Mortality in the Healthy Elderly – New England Journal of Medicine (free) (via @EricTopol)

Related Studies: Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly – New England Journal of Medicine (free) AND Effect of Aspirin on Disability-free Survival in the Healthy Elderly – New England Journal of Medicine (free)

Commentaries: Daily low-dose aspirin found to have no effect on healthy life span in older people- NIH News Releases (free) AND Low-Dose Aspirin Late in Life? Healthy People May Not Need It – The New York Times (10 articles per month are free)

 

2 – WHO water, sanitation and hygiene strategy 2018-2025 – World Health Organization (free PDF)

 

3 – Optimizing medications in older adults with cognitive impairment: Considerations for primary care clinicians – Canadian Family Physicians (free)

 

4 – Viewpoint: Antibiotics for Sepsis—Finding the Equilibrium – JAMA (free for a limited period)

 

5 – Shared Decision-Making: Staying Focused on the Ultimate Goal – NEJM Catalyst (free)

 

6 – Ig Nobel win for kidney stone removing roller-coaster – BBC (free)

Related: Ig Nobel prizes honor do-it-yourself colonoscopies, a curious use for postage stamps, and other peculiar research – Science (free)

 

7 – Can health services handle the Apple Watch? – BBC (free)

Related: The New Apple Watch 4: Cardiac Accuracy Unknown, “Game-Changing” Benefits Overblown – The Skeptical Cardiologist (free) AND The New ECG Apple Watch Could do More Harm Than Good – Wired (a few articles per month are free)

See also: New Watch can Help Doctors Monitor your Heart in Real Time (free commentaries)

 

8 – Patients vs. paywalls: Is the U.S. ready for open-access publishing? – STAT (free)

Related: Scientific publishing is a rip-off. We fund the research – it should be free – The Guardian (free) AND cOAlition S: Making Open Access a Reality by 2020 (free Statement and commentaries)

 

9 – Prevalence of Chronic Pain and High-Impact Chronic Pain Among Adults — United States, 2016 – Centers for Disease Control and Prevention (free)

Commentaries: Chronic Pain Affects 20% of Americans, CDC Reports – MedPage Today (free registration required) AND CDC: About 1 in 5 US Adults Have Chronic Pain – MPR (free) AND One-fifth of American adults experience chronic pain, CDC estimates – CNBC (free)

 

10 – Total Medicare Costs Associated With Diagnosis and Treatment of Prostate Cancer in Elderly Men – JAMA Oncology (link to abstract – $ for full-text)

Commentaries: Are Older Prostate Cancer Patients Overtreated? – MedPage Today (free registration required)

 


Systematic Review: Are Invasive Procedures Effective for Chronic Pain?

14 Sep, 2018 | 02:28h | UTC

Are Invasive Procedures Effective for Chronic Pain? A Systematic Review – Pain Medicine (free)

Commentaries: New study questions effectiveness of invasive procedures for chronic pain – The Reis Group (free) AND Invasive Procedures For Chronic Pain Have Not Been Proven to Work – MedicalResearch.com (free)

Related: Needless procedures: knee arthroscopy is one of the most common but least effective surgeries – The Conversation (free)

 


Report: Global Cancer Statistics 2018

14 Sep, 2018 | 02:29h | UTC

Global Cancer Statistics 2018: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries – CA: A Cancer Journal for Clinicians (free)

See also: Latest global cancer data: Cancer burden rises to 18.1 million new cases and 9.6 million cancer deaths in 2018 – International Agency for Research on Cancer (free PDF)

Infographic: Global Cancer Data 2018 (free)

Commentaries: WHO: 9.6 million cancer deaths, 18 million new cases this year – UPI (free) AND Cancer will kill nearly 10 million people this year, report estimates – CNN (free) AND Cancer deaths rise to 9.6 million as populations grow and age – Reuters (free)

 


The New ECG Apple Watch Could do More Harm Than Good

14 Sep, 2018 | 02:27h | UTC

The New ECG Apple Watch Could do More Harm Than Good – Wired (a few articles per month are free) (via @EricTopol)

See also: New Watch can Help Doctors Monitor your Heart in Real Time (free commentaries)

 


Perspective: What 21st Century Health Care Should Learn from 20th Century Business

14 Sep, 2018 | 02:28h | UTC

What 21st Century Health Care Should Learn from 20th Century Business – NEJM Catalyst (free)

 


Thousands of Scientists Publish a Paper Every Five Days

14 Sep, 2018 | 02:25h | UTC

Thousands of scientists publish a paper every five days – Nature (free)

Related: Some scientists publish more than 70 papers a year. Here’s how—and why—they do it – Science (free)

 


Opinion – Scientific Publishing is a Rip-off. We Fund the Research – It Should be Free

14 Sep, 2018 | 02:26h | UTC

Scientific publishing is a rip-off. We fund the research – it should be free – The Guardian (free)

Related: cOAlition S: Making Open Access a Reality by 2020 (free Statement and commentaries)

 


Cohort Study: Effect of Mammography Screening on Breast Cancer Mortality

14 Sep, 2018 | 02:25h | UTC

Effect of organised mammography screening on breast cancer mortality: A population‐based cohort study in Norway – International Journal of Cancer (free)

Commentaries: Breast cancer screening does not reduce mortality – eCancer News (free) AND Danish study attributes improved treatment, not screening, to decline in breast cancer deaths – Health Imaging (free)

 


NICE Guideline: Chronic Heart Failure in Adults

14 Sep, 2018 | 02:20h | UTC

Chronic heart failure in adults: diagnosis and management – National Institute for Health and Care Excellence (free)

 


Meta-Analysis: Fatal Toxic Effects Associated With Immune Checkpoint Inhibitors

14 Sep, 2018 | 02:22h | UTC

Fatal Toxic Effects Associated With Immune Checkpoint Inhibitors: A Systematic Review and Meta-analysis – JAMA Oncology (free for a limited period)

Commentaries: Study Discerns Rare Risks of Fatal Side Effects From Cancer Immunotherapy – AJMC (free) AND Fatal Toxicities Rare With Checkpoint Inhibitors – MedicalResearch.com (free)

Related Guidelines: Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline (free) AND Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group (free)

Related Review: New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management – Critical Care (free)

 


FDA Takes New Steps to Address Epidemic of Youth E-Cigarette Use

14 Sep, 2018 | 02:07h | UTC

FDA takes new steps to address epidemic of youth e-cigarette use, including a historic action against more than 1,300 retailers and 5 major manufacturers for their roles perpetuating youth access (free)

Commentaries: FDA: we might have to ban some e-cigarettes to stop teens from vaping – VOX (free) AND FDA Intensifies Crackdown On E-Cigarette Sales To Teenagers – NPR (free)

“The agency is eyeing a crackdown on flavored e-cigs in the face of an “epidemic” of teen use.” (from VOX)

 


Review: Arterial Hypertension

14 Sep, 2018 | 02:18h | UTC

Arterial Hypertension: Diagnosis and treatment – Deutsches Ärzteblatt international (free)

 


Overdiagnosis: Causes and Consequences in Primary Health Care

14 Sep, 2018 | 02:09h | UTC

Overdiagnosis: causes and consequences in primary health care – Canadian Family Physician (free) (via @cantaskforce)

Related: Overdiagnosis across medical disciplines: a scoping review – The BMJ Open (free) AND Too much medical care: bad for you, bad for health care systems – STAT News (free) AND Overdiagnosis: what it is and what it isn’t – BMJ Evidence Based Medicine (free) AND Position Paper on Overdiagnosis and Action to be Taken – Wonca (free PDF)

 


European Union Standards for Tuberculosis Care

14 Sep, 2018 | 02:19h | UTC

European Union Standards for Tuberculosis Care – European Centre for Disease Prevention and Control (free PDF in several languages) (via @ECDC_TB and @Onisillos)

 


Meta-Analysis: Restrictive vs. Liberal Transfusion Strategies in Cardiac Surgery

14 Sep, 2018 | 02:07h | UTC

Restrictive compared with liberal red cell transfusion strategies in cardiac surgery: a meta-analysis – European Heart Journal (free)

Related study: Outcomes after Restrictive or Liberal Transfusion for Cardiac Surgery (link to abstract)

 


Study: Factors Associated With Long-term Benzodiazepine Use Among Older Adults

14 Sep, 2018 | 02:04h | UTC

Factors Associated With Long-term Benzodiazepine Use Among Older Adults – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: 1 in 4 Older Adults Prescribed a Benzodiazepine Goes on to Risky Long-Term Use, Study Finds – Michigan Medicine, via NewsWise (free) AND Long-Term Benzodiazepine Use Common Among Older Adults – Physician’s First Watch (free) AND Factors Predicting Long-term Benzodiazepine Use Identified – Medscape (free registration required) AND Larger Number of Benzodiazepine Pills in Initial Prescription Associated With Long Term Use – MedicalResearch.com (free)

Related: A Quiet Drug Problem Among the Elderly – The New York Times (free) AND Our Other Prescription Drug Problem – New England Journal of Medicine (free) AND Benzodiazepines: our other prescription drug epidemic – STAT (free) AND Deprescribing benzodiazepine receptor agonists – Canadian Family Physician (free)

 


USPSTF Draft Statement: Ocular Prophylaxis for Gonococcal Ophthalmia Neonatorum

14 Sep, 2018 | 02:16h | UTC

USPSTF Draft Recommendation Statement: Ocular Prophylaxis for Gonococcal Ophthalmia Neonatorum (free)

Commentaries: USPSTF Again Recommends Ointment to Prevent Gonococcal Eye Infection in Newborns – Physician’s First Watch (free) AND USPSTF Reaffirms Ocular Prophylaxis for All Newborns – MedPage Today (free)

 


Report: Egg Freezing in Fertility Treatment Trends and Figures

14 Sep, 2018 | 02:06h | UTC

Egg freezing in fertility treatment Trends and figures: 2010-2016 – Human Fertilisation and Embryology Authority (HFEA) (free PDF)

Press release: Age is the key factor for egg freezing success says new HFEA report, as overall treatment numbers remain low (free)

Commentaries: Expert reaction to HFEA report on trends in egg freezing – Science Media Centre (free) AND Freeze eggs before 35 for a better chance of IVF success, says report – The Guardian (free)

 


Randomized Trial: Piperacillin-Tazobactam vs for Patients With E coli or Klebsiella pneumoniae Bloodstream Infection and Ceftriaxone Resistance

14 Sep, 2018 | 02:03h | UTC

Effect of Piperacillin-Tazobactam vs Meropenem on 30-Day Mortality for Patients With E coli or Klebsiella pneumoniae Bloodstream Infection and Ceftriaxone Resistance: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Video Summary: Effect of Piperacillin-Tazobactam vs Meropenem on Mortality in Gram-Negative Bloodstream Infection – JAMA (free)

Commentaries: Combo antibiotic found inferior for MDR bloodstream infections – CIDRAP (free) AND Drug Combo No Better for Hard-to-Treat Bloodstream Infections – Medscape (free registration required)

“The results do not support the use of Pip/Tazo as 30 d mortality was 12.3% in Pip/Tazo vs 3.7% in Mero arms” (via @CarlosdelRio7 see Tweet)

 


Opinion: Are We Being Misled About Precision Medicine?

14 Sep, 2018 | 02:01h | UTC

Are We Being Misled About Precision Medicine? – The New York Times (10 articles per month are free)

“Doctors and hospitals love to talk about the cancer patients they’ve saved, and reporters love to write about them. But deaths still vastly outnumber the rare successes.”

 


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