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“Overall, little or no relation was found between the USNWR ranking of the medical school from which a physician graduated and subsequent patient mortality or readmission rates.”

9 – Modifying the consistency of food and fluids for swallowing difficulties in dementia – Cochrane Library (free for a limited period)

Summary: Modifying the consistency of food and fluids for swallowing difficulties in dementia (free)

“We are uncertain about the immediate and long-term effects of modifying the consistency of fluid for swallowing difficulties in dementia”

10 – Healthy dietary indices and risk of depressive outcomes: a systematic review and meta-analysis of observational studies – Molecular Psychiatry (link to abstract – $ for full-text)

Commentaries: Plant-rich diets may help prevent depression – new evidence – The Conversation (free) AND Eating a Mediterranean diet ‘may lower your risk of depression’ – NHS Choices (free) AND Expert reaction to observational studies on diet and depression – Science Media Centre (free) AND Mediterranean diet could prevent depression, new study finds – CNN (free)

“The current evidence is not sufficient to prove plant-rich diets can prevent depression as most of the evidence so far simply shows that those with poorer mental health eat worse, so it may be that those more prone to depression also choose less health” (from CNN)

Tue, September 25 – 10 Stories of The Day!

25 Sep, 2018 | 01:21h | UTC

1 – Noncommunicable Diseases Country Profiles 2018 – World Health Organization (free PDF)

See also: NCDs profile by country (free)

2 – Transcatheter Mitral-Valve Repair in Patients with Heart Failure – New England Journal of Medicine (free)

Commentary: COAPT: MitraClip Reduces Repeat Hospitalizations, Mortality in Functional MR Patients With Severe HF – TCTMD (free)

“Physicians responded with shock and excitement to findings, but struggled to reconcile the results with the MITRA-FR trial.” (from TCTMD)

3 – Effect of Variation in Published Stroke Rates on the Net Clinical Benefit of Anticoagulation for Atrial Fibrillation – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentary: Benefit of anticoagulation for stroke prevention may vary in patients with afib, study finds – ACP Internist (free)

4 – Review: Streptococcal toxic shock syndrome in the intensive care unit – Annals of Intensive Care (free)

Source: Critical Care Reviews Newsletter

5 – Targeted temperature management in patients with intracerebral haemorrhage, subarachnoid haemorrhage, or acute ischaemic stroke: consensus recommendations – British Journal of Anaesthesia (free)

Source: Critical Care Reviews Newsletter

6 – Podcast: #115 Geriatric Depression – The Curbsiders Internal Medicine Podcast (free)

Summary: #115 Geriatric Depression: Diagnosis, Antidepressants, and More (free)

7 – Ann Robinson’s research reviews, 24 September 2018 – The BMJ Opinion (free)

Ann Robinson reviews the latest research from the top medical journals.

8 – Congratulations. Your Study Went Nowhere – The New York Times (10 articles per month are free) (via @kennylinafp)

“Researchers should embrace negative results instead of accentuating the positive, which is one of several biases that can lead to bad science.”

9 – Just Started! Free Online Course: Antibiotic Stewardship – Stanford University and Coursera (via @classcentral)

10 – Double check patients with ‘penicillin allergy’ to avoid increased MRSA risk – NICE News and Features (free)

Related Study: Risk of Meticillin Resistant Staphylococcus Aureus and Clostridium Difficile in Patients with a Documented Penicillin Allergy (free article and commentaries)

Wed, September 26 – 10 Stories of The Day!

26 Sep, 2018 | 00:20h | UTC

1 – Five-Year Follow-up of Antibiotic Therapy for Uncomplicated Acute Appendicitis in the APPAC Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Podcast: Treating Appendicitis Without Surgery – 5-Year Follow-up from a Randomized Clinical Trial of Antibiotic Treatment (free)

Video Summary: Five-Year Follow-up of Patients Given Antibiotic Therapy for Uncomplicated Acute Appendicitis (free)

Commentaries: Pills for appendicitis? Surgery often not needed, study says – STAT (free) AND Antibiotics Alone Seem Reasonable for Uncomplicated Appendicitis in Adults – Physician’s First Watch (free) AND Appendicitis? Antibiotics May Be All You Need – The New York Times (10 articles per month are free)

Related: Randomized clinical trial of antibiotic therapy for uncomplicated appendicitis (link to abstract and commentaries) AND Antibiotics Versus Surgical Therapy for Uncomplicated Appendicitis (link to abstract and commentaries) AND Antibiotic Therapy versus Appendectomy for Acute Uncomplicated Appendicitis (free study and commentaries) AND New appendicitis guideline incorporates the possibility of non-operative treatment for uncomplicated disease (free guideline)

2 – Type 1 Diabetes in Children and Adolescents: A Position Statement by the American Diabetes Association – Diabetes Care (free)

3 – Recovery of Over-Ground Walking after Chronic Motor Complete Spinal Cord Injury – New England Journal of Medicine (free)

Commentaries: Technology and therapy help individuals with chronic spinal cord injuries take steps – University of Louisville (free) AND Epidural Stimulation Helps Patients Walk After Total Paralysis – MedPage Today (free registration required) AND Paralyzed Patients Able to Walk Following Epidural Stimulation, Intense Rehab – Physician’s First Watch (free)

4 – Prevalence of drug–herb and drug–supplement interactions in older adults: a cross-sectional survey – British Journal of General Practice (free)

Commentaries: New study finds concurrent use of prescription drugs and dietary supplements could pose health risks – University of Hertfordshire (free) AND Concerns raised about older adults mixing prescription drugs and herbal remedies – NHS Choices (free)

5 – Development and Validation of Deep Learning–based Automatic Detection Algorithm for Malignant Pulmonary Nodules on Chest Radiographs – Radiology (link to abstract – $ for full-text)

Commentary: Deep learning algorithm detects malignant pulmonary nodules better than radiologists – Radiology Business (free)

Related Studies: Deep Learning for the Diagnosis of Fibrotic Lung Disease (link to abstract and commentaries) AND Can Artificial Intelligence Reliably Report Chest X-Rays? (free study and commentaries) AND Artificial Intelligence Can Determine Lung Cancer Type (link to abstract and commentaries)

6 – Measuring human capital: a systematic analysis of 195 countries and territories, 1990–2016 – The Lancet (free)

Commentary: Unprecedented study finds nations failing to invest in education and health care at risk of slow economic growth – Institute for Health Metrics and Evaluation (free)

Infographic: What is human capital and why is it relevant? – Institute for Health Metrics and Evaluation (free)

“The first-ever study ranking countries by human capital has been published in @TheLancet. This novel approach looks at nations’ investments in health and education and their relation to GDP growth” (via @IHME_UW see Tweet)

7 – Pharmacokinetics–pharmacodynamics issues relevant for the clinical use of beta-lactam antibiotics in critically ill patients – Critical Care (free)

Related: Extended Antibiotic Infusions Could Save Lives: Here’s How to Do It (free commentary) AND Mortality lower with prolonged vs. short-term IV infusion of antipseudomonal beta-lactams (link to abstract and free commentary)

8 – Ebola response faces ‘grave obstacles’ as count hits 150 – CIDRAP (free)

9 – Adverse outcomes after arthroscopic partial meniscectomy: a study of 700 000 procedures in the national Hospital Episode Statistics database for England – The Lancet (free)

Invited Commentary: Potential harms of isolated arthroscopic partial meniscectomy (free)

10 – Effect of Algorithm-Based Therapy vs Usual Care on Clinical Success and Serious Adverse Events in Patients with Staphylococcal Bacteremia: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Treatment Algorithms for Staphylococcal Bacteremia: Improving Clinical Care and Enhancing Antimicrobial Stewardship (free for a limited period)

Commentary: Algorithm may reduce antibiotics for staph bloodstream infections – CIDRAP (free)