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Wed, October 10 – 10 Stories of The Day!

10 Oct, 2018 | 00:29h | UTC

 

1 – Cluster Randomized Clinical Trial of FAITH (Faith-Based Approaches in the Treatment of Hypertension) in Blacks – Circulation: Cardiovascular Quality and Outcomes (free)

Editorial: Of Barbershops and Churches: Can Community-Based Interventions Improve Cardiovascular Risk in High-Risk Patients? (free)

Commentaries: Faith-based approach to changing lifestyle lowers blood pressure – AHA Newsroom (free) AND How church communities can help lower African-Americans’ blood pressure – CNN (free) AND Church-Based Lifestyle Intervention Shows Promise for Lowering BP in Hypertensive African-Americans – TCTMD (free)

Related Study: Cluster-Randomized Trial of Blood-Pressure Reduction in Black Barbershops (free study and commentaries)

 

2 – Fluoroquinolone and quinolone antibiotics: PRAC recommends new restrictions on use following review of disabling and potentially long-lasting side effects – European Medicines Agency (free)

Commentaries: EMA committee recommends restrictions on fluoroquinolone, quinolone antibiotics – Reuters (free) AND PRAC Recommends Restrictions on Fluoroquinolone, Quinolones – Medscape (free registration required)

Related FDA Safety Alert: Warnings for Fluoroquinolones on Risks of Mental Health and Low Blood Sugar Adverse Reactions (free statement and commentaries)

 

3 – Evidence synthesis for health policy and systems: a methods guide – World Health Organization (free PDF) (via @trishgreenhalgh)

 

4 – Non-celiac gluten/wheat sensitivity (NCGS)—a currently undefined disorder without validated diagnostic criteria and of unknown prevalence – Position statement of the task force on food allergy of the German Society of Allergology and Clinical Immunology (DGAKI) (free)

 

5 – Review: Managing the Patient with Heart Failure in the Emergency Department – European Heart Journal (free) (via @gonzaeperez)

 

6 – Review: Office approach to small fiber neuropathy – Cleveland Clinic Journal of Medicine (free)

 

7 – Review: Bicuspid aortic valve: Basics and beyond – Cleveland Clinic Journal of Medicine (free)

 

8 – Nine ways research could save the NHS money – NHS Dissemination Centre (free)

New infographic series with selected NIHR Signals covering a range of treatments and initiatives that are cost effective.

 

9 – 800,000 people kill themselves every year. What can we do? – The Guardian (free) (via @onisillos)

Related Guidelines: Preventing suicide: A community engagement toolkit – World Health Organization (free PDF) AND Preventing suicide in community and custodial settings – National Institute for Health and Care Excellence (free)

“In too many places mental health support services are non-existent and those with treatable conditions are criminalized. Bold action is long overdue”

 

10 – Electronic cigarette explosion and burn injuries, US Emergency Departments 2015–2017 – Tobacco Control (link to abstract – $ for full-text)

Commentaries: E-cigarette explosion and burn injuries have been underestimated by federal agencies – George Mason University (free) AND Study: E-Cigarette Injuries Drastically Underestimated – MedPage Today (free registration required)

 


Study: Acceleration of BMI in Early Childhood and Risk of Sustained Obesity

5 Oct, 2018 | 02:45h | UTC

Acceleration of BMI in Early Childhood and Risk of Sustained Obesity – New England Journal of Medicine (link to abstract – $ for full-text)

Quick Take Video Summary: Childhood BMI Acceleration and Sustained Obesity (free)

Commentary: BMI in Early Childhood and Sustained Obesity – American College of Cardiology (free)

 


Mon, October 8 – 10 Stories of The Day!

8 Oct, 2018 | 00:01h | UTC

 

1 – Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) – Diabetes Care (free PDF)

Commentaries: New Consensus Report from the American Diabetes Association® (ADA) and the European Association for the Study of Diabetes (EASD) Calls for Paradigm Shift to Patient-Centered Care for Type 2 Diabetes – American Diabetes Association (free) AND New EASD-ADA consensus guidelines on managing hyperglycaemia in type 2 diabetes launched at EASD meeting – Diabetologia (free)

Related Guidelines: WHO Guideline: Medicines for the Treatment of Diabetes in Low-Resource Settings (free guideline and commentaries) AND Pharmacologic Glycemic Management of Type 2 Diabetes in Adults – Canadian Journal of Diabetes (free) AND ADA 2018 Standards of Medical Care in Diabetes (free guideline and commentaries) AND ACP Guideline: Hemoglobin A1c Targets for Glycemic Control in Type 2 Diabetes (free guideline and commentaries)

 

2 – Supplement: ESMO Updated Clinical Practice Guidelines – European Society of Medical Oncology (free)

 

3 – Perspective: What the tests don’t show – The Washington Post (a few articles per month are free)

“Many doctors are surprisingly bad at reading test results and/or fail to grasp how false positives work. This is putting patients at risk” (via @pash22 see Tweet)

 

4 – Perspective: Why Employers Should Stop Giving Away Snacks – Pacific Standart (free)

Source: Global Health NOW Newsletter

 

5 – Outpatient antibiotics widely prescribed without an infection diagnosis – CIDRAP (free)

Related Commentary: Study Finds Almost Half of Antibiotic Prescriptions Written Without a Diagnosis – Pharmacy Times (free)

 

6 – Review: The Diagnosis and Treatment of Anxiety Disorders – Deutsches Ärzteblatt international (free)

 

7 – Review: Cardiovascular disease and COPD: dangerous liaisons? – European Respiratory Review (free)

 

8 – COPD Guidelines: A Review of the 2018 GOLD Report – Mayo Clinic Proceedings (free)

Related: Highlights from the New GOLD COPD Guidelines (free guideline and commentaries)

 

9 – Closed-loop insulin delivery in suboptimally controlled type 1 diabetes: a multicentre, 12-week randomised trial – The Lancet (free)

Commentaries: Enlarging the loop: closed-loop insulin delivery for type 1 diabetes – The Lancet (free) AND Hybrid Closed Loop System Aid for Tighter Glucose Control – MedPage Today (free registration required)

 

10 – Effectiveness of Online vs In-Person Care for Adults With Psoriasis: A Randomized Clinical Trial – JAMA Network Open (free)

Commentary: Treating psoriasis in the future could be as easy as going online – USC News (free)

 


Perspective: Given Their Potential for Harm, It’s Time to Focus on the Safety of Supplements

5 Oct, 2018 | 02:41h | UTC

Given Their Potential for Harm, It’s Time to Focus on the Safety of Supplements – JAMA (free for a limited period) (via @NUNESDOC)

“About 23 000 visits to emergency departments each year can be attributed to adverse events from dietary supplements.”

 


Meta-Analysis: Effects of Vitamin D Supplementation on Musculoskeletal Health

5 Oct, 2018 | 02:44h | UTC

Effects of vitamin D supplementation on musculoskeletal health: a systematic review, meta-analysis, and trial sequential analysis – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

Commentaries: The Lancet Diabetes & Endocrinology: Vitamin D supplementation in adults does not prevent fractures, falls or improve bone mineral density – The Lancet (free) AND Vitamin D supplements don’t help bone health, major study concludes – The Guardian (free) AND Millions of Americans take vitamin D. Most should just stop – VOX (free)

Related: Vitamin D, the Sunshine Supplement, Has Shadowy Money Behind It (free commentaries and NICE Guideline) AND Vitamin D Not Linked to Fracture Risk (free study and commentaries)

 


Study: Effect of Lorcaserin on Prevention and Remission of Type 2 Diabetes in Overweight and Obese Patients

5 Oct, 2018 | 02:38h | UTC

Effect of lorcaserin on prevention and remission of type 2 diabetes in overweight and obese patients (CAMELLIA-TIMI 61): a randomised, placebo-controlled trial – The Lancet (link to abstract – $ for full-text)

Commentaries: Weight loss drug shows positive effect on diabetes – Brigham and Women’s Hospital (free) AND Weight Loss Drug Helped Prevent Diabetes in Overweight People – MedPage Today (free registration required)

Related Article: Cardiovascular Safety of Lorcaserin in Overweight or Obese Patients (link to abstract and commentaries)

 


Clinical Update: Immune Checkpoint Inhibitor Toxicity in 2018

5 Oct, 2018 | 02:42h | UTC

Immune Checkpoint Inhibitor Toxicity in 2018 – JAMA (free for a limited period)

Related Guidelines: Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline (free) AND Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group (free)

Related Review: New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management – Critical Care (free)

 


Report: The Future of Healthcare

5 Oct, 2018 | 02:39h | UTC

The future of healthcare – The Economist (free PDF)

 


Perspective: When Conventional Wisdom Is Put on Trial

5 Oct, 2018 | 02:40h | UTC

When Conventional Wisdom Is Put on Trial – UNDark (free) (via @EricTopol)

“The author of “Randomistas” shows how randomized trials have overturned many popular findings, from hormone therapy to the benefits of multivitamins.”

 


Perspective: New Tools in the Ebola Arsenal

5 Oct, 2018 | 02:37h | UTC

New Tools in the Ebola Arsenal – New England Journal of Medicine (free)

Related: DRC Ebola cases rise as security concerns continue – CIDRAP (free) AND Officials fear Ebola epidemic may be spinning beyond their control, threatening regional spread – STAT (free) AND Ebola Likely to Spread From Congo to Uganda, W.H.O. Says – The New York Times (10 articles per month are free)

 


Study: Collaboration Between Academics and Industry in Clinical Trials

5 Oct, 2018 | 02:37h | UTC

Collaboration between academics and industry in clinical trials: cross sectional study of publications and survey of lead academic authors – The BMJ (free)

Commentaries: Shining a light on industry collaboration – The BMJ Opinion (free) AND Industry funders involved in most aspects of funded trials – OnMedica (free)

 


Meta-Analysis: Prescribed Exercise with Compression vs Compression Alone in Treating Patients With Venous Leg Ulcers

5 Oct, 2018 | 02:36h | UTC

Prescribed Exercise With Compression vs Compression Alone in Treating Patients With Venous Leg Ulcers: A Systematic Review and Meta-analysis – JAMA Dermatology (link to abstract – $ for full-text)

Commentaries: Adding Exercise to Compression Improves Outcomes in Venous Leg Ulcers – Physcian’s First Watch (free) AND Compressions May Remedy Venous Leg Ulcers – MedPage Today (free)

 


Study: The Projected Timeframe Until Cervical Cancer Elimination in Australia

5 Oct, 2018 | 02:31h | UTC

The projected timeframe until cervical cancer elimination in Australia: a modelling study – The Lancet Public Health (free)

Commentaries: Modelling cervical cancer elimination – The Lancet Public Health (free) AND Australia on track to wipe out cervical cancer within 20 years – The Guardian (free) AND In Australia, Cervical Cancer Could Soon Be Eliminated – The New York Times (10 articles per month are free)

 


NICE Guideline: Renal Replacement Therapy

5 Oct, 2018 | 02:31h | UTC

Renal replacement therapy and conservative management – National Institute for Health and Care Excellence (free)

 


Global, Regional, and National Burden of Parkinson’s Disease

5 Oct, 2018 | 02:30h | UTC

Global, regional, and national burden of Parkinson’s disease, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 – The Lancet Neurology (free)

Invited Commentary: The burden of Parkinson’s disease: a worldwide perspective (free)

“In 2016, 6·1 million people worldwide had Parkinson’s disease, 2·9 million (48%) women & 3·2 million (52%) men; the increase in burden since 1990 was not exclusively explained by an increasing number of older people” (via @TheLancet see Tweet)

 


Recommendations for the use of Electrophysiological Study

5 Oct, 2018 | 02:28h | UTC

Recommendations for the use of Electrophysiological Study: Update 2018 – Helenic Journal of Cardiology (free)

 


Enhanced Recovery After Surgery Guidelines for Perioperative Care in Esophagectomy

5 Oct, 2018 | 02:29h | UTC

Guidelines for Perioperative Care in Esophagectomy: Enhanced Recovery After Surgery (ERAS®) Society Recommendations – World Journal of Surgery (free for a limited period)

 


Study: Evaluating Progression-Free Survival as a Surrogate Outcome for Health-Related Quality of Life in Oncology

5 Oct, 2018 | 02:26h | UTC

Evaluating Progression-Free Survival as a Surrogate Outcome for Health-Related Quality of Life in Oncology: A Systematic Review and Quantitative Analysis – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: Health-related quality of life overlooked in cancer drug studies – McMaster University (free) AND Investigators Question the Use of PFS as a Surrogate End Point – Cancer Therapy Advisor (free) AND Preventing tumor spread may not improve quality of life – Reuters (free) AND Research: Consider quality of life when evaluating cancer drug studies – UPI (free)

 


Guideline: Congenital Adrenal Hyperplasia Due to Steroid 21-Hydroxylase Deficiency

5 Oct, 2018 | 02:27h | UTC

Congenital Adrenal Hyperplasia Due to Steroid 21-Hydroxylase Deficiency: An Endocrine Society Clinical Practice Guideline – Journal of Clinical Endocrinology and Metabolism (free PDF)

News Release: Managing congenital adrenal hyperplasia requires shared decisions among patients, families, and heal – The Endocrine Society (free)

 


ACOG Committee Opinion: Well-Woman Visit

5 Oct, 2018 | 02:25h | UTC

Well-Woman Visit – American College of Obstetrics and Gynecology (free)

News Release: ACOG and WPSI Release Materials to Support Women’s Preventive Care at Every Life Stage (free)

Commentary: ACOG Stresses Role of Ob/Gyns in Preventive Care For Women – Medscape (free registration required)

 


Study: Teen Cannabis Use and Cognitive Development

5 Oct, 2018 | 02:23h | UTC

A Population-Based Analysis of the Relationship Between Substance Use and Adolescent Cognitive Development – American Journal of Psychiatry (link to abstract – $ for full-text)

Commentaries: Teen cannabis use is not without risk to cognitive development – Université de Montréal (free) AND Cannabis ‘more harmful than alcohol’ for teen brains – BBC (free)

 


Two Antiplatelet Drugs may Prevent Further Strokes but Increase Major Bleeds

5 Oct, 2018 | 02:24h | UTC

Two antiplatelet drugs may prevent further strokes but increase major bleeds – NIHR Signal (free)

Original Article: Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA – New England Journal of Medicine (link to abstract – $ for full-text)

 


Randomized Trial: Early Surgery vs Physical Therapy on Knee Function Among Patients With Nonobstructive Meniscal Tears

5 Oct, 2018 | 02:21h | UTC

Effect of Early Surgery vs Physical Therapy on Knee Function Among Patients With Nonobstructive Meniscal Tears: The ESCAPE Randomized Clinical Trial – JAMA (free for a limited period)

Commentary: PT an Alternative to Surgery for Some Meniscal Tears – Physician’s First Watch (free)

Related: Adverse Outcomes After Arthroscopic Partial Meniscectomy (free study, commentary and guideline on the subject)

“Our Dutch multi center RCT demonstrates noninferiority of physical therapy compared with early surgery with arthroscopic partial meniscectomy for improving self-reported knee function in patients with nonobstructive meniscal tears.” (via @RudolfPoolman see Tweet)

 


Ten Principles for More Conservative, Care-Full Diagnosis

5 Oct, 2018 | 02:22h | UTC

Ten Principles for More Conservative, Care-Full Diagnosis – Annals of Internal Medicine (free) (via @EricTopol)

 


Guideline: Management of Malignant Pleural Effusions

5 Oct, 2018 | 02:21h | UTC

Management of Malignant Pleural Effusions. An Official ATS/STS/STR Clinical Practice Guideline – American Journal of Respiratory and Critical Care Medicine (free)

Related Guideline: ERS/EACTS statement on the management of malignant pleural effusions – European Respiratory Journal (free)

 


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