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“Some experts question whether the surgery is being done too often or too soon on patients who have not adequately explored less invasive approaches.”

Antibiotics May Soon Become Useless. Now What?

16 Oct, 2018 | 21:27h | UTC

Antibiotics May Soon Become Useless. Now What? – WIRED (a few articles per month are free)

Cohort Study: Outcomes of Patients With Asymptomatic Aortic Stenosis

16 Oct, 2018 | 21:25h | UTC

Outcomes of Patients With Asymptomatic Aortic Stenosis Followed Up in Heart Valve Clinics – JAMA Cardiology (free)

Commentaries: Study IDs predictors of mortality in asymptomatic aortic stenosis – Cardiovascular Business (free) AND Silent Aortic Stenosis Outcomes Good With Close Surveillance – MedPage Today (free registration required)

Study: Screening with Breast Tomosynthesis vs. Mammography

16 Oct, 2018 | 21:25h | UTC

One-view breast tomosynthesis versus two-view mammography in the Malmö Breast Tomosynthesis Screening Trial (MBTST): a prospective, population-based, diagnostic accuracy study – The Lancet Oncology (link to abstract – $ for full-text)

Commentary: 3D mammography detected 34% more breast cancers in screening – Lund University (free)

Study: Biomarkers of Dairy Fat Consumption and Incidence of Type 2 Diabetes

16 Oct, 2018 | 21:24h | UTC

Fatty acid biomarkers of dairy fat consumption and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies – PLOS Medicine (free)

Commentaries: Could cheese help prevent type 2 diabetes? – The Conversation (free) AND Markers of dairy fat consumption linked to lower risk of type two diabetes – Medical Research Council (free)

Tue, October 16 – 10 Stories of The Day!

16 Oct, 2018 | 00:01h | UTC

1 – Attention deficit hyperactivity disorder late birthdate effect common in both high and low prescribing international jurisdictions: systematic review – The Journal of Child Psychology and Psychiatry (free)

Commentary: Global study finds youngest in class more likely to be diagnosed with ADHD – University of Adelaide (free)

“Youngest kids in class much more likely get ADHD diagnosis than oldest. Bad News: Simple immaturity now turned into mental illness & treated with meds” (via @AllenFrancesMD see Tweet)

2 – Many Analysts, One Data Set: Making Transparent How Variations in Analytic Choices Affect Results – Advances in Methods and Practices in Psychological Science (free) (via @f_g_zampieri)

“This is one of most important studies published this century. 29 teams used same data set to address same research question; estimated effect sizes ranged from 0.89 to 2.93 in odds-ratio units. Dramatic implications for observational research.” (via @hmkyale see Tweet)

3 – WHO Statement: Ebola virus disease – Democratic Republic of the Congo – World Health Organization (free)

4 – A pandemic killing tens of millions of people is a real possibility — and we are not prepared for it – VOX (free)

Related: Innovation for Pandemics (free perspectives and video on the subject)

5 – Ann Robinson’s research reviews, 15 October 2018 – The BMJ Opinion (free)

Ann Robinson reviews the latest research from the top medical journals.

6 – Demystifying serotonin syndrome (or serotonin toxicity) – Canadian Family Physician (free)

7 – Approach to the detection and management of chronic kidney disease: What primary care providers need to know – Canadian Family Physician (free)

8 – Oliguria in critically ill patients: a narrative review – Journal of Nephrology (free)

Source: Critical Care Reviews Newsletter

9 – β-Blocker Use in Pregnancy and the Risk for Congenital Malformations: An International Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Beta-Blocker Use in First Trimester Seems Safe – Physician’s First Watch (free) AND Beta-blocker Use in Pregnancy Doesn’t Up Birth Defect Risk, Study Suggests – TCTMD (free)

10 – Identity inference of genomic data using long-range familial searches – Science (free for a limited period)

Commentaries: Most White Americans’ DNA Can Be Identified Through Genealogy Databases – The New York Times (10 articles per month are free) AND How an Unlikely Family History Website Transformed Cold Case Investigations – The New York Times (10 articles per month are free) AND ‘We are increasingly exposed’: New studies show how easy it is to identify people using genetic databases – STAT (free) AND Supercharged crime-scene DNA analysis sparks privacy concerns – Nature (free)

Meta-Analysis: Effect of Antidepressants and Psychological Therapies in Irritable Bowel Syndrome

16 Oct, 2018 | 21:23h | UTC

Effect of Antidepressants and Psychological Therapies in Irritable Bowel Syndrome: An Updated Systematic Review and Meta-analysis – The American Journal of Gastroenterology (link to abstract – $ for full-text)

Commentary: Antidepressants and psychological therapies reduce IBS symptoms, meta-analysis finds – ACP Gastroenterology (free) AND Antidepressants, psychotherapy may help ease irritable bowel syndrome – Reuters (free)

Cohort Study: Association of Depression with Risk of Incident Systemic Lupus Erythematosus

16 Oct, 2018 | 21:22h | UTC

Association of Depression With Risk of Incident Systemic Lupus Erythematosus in Women Assessed Across 2 Decades – JAMA Psychiatry (link to abstract – $ for full-text)

Commentaries: Depression May Increase Risk of Developing an Autoimmune Disease – MedicalResearch.com (free) AND Depression Tied to Double the Risk for Lupus in Women – Medscape (free registration required)

Mon, October 15 – 10 Stories of The Day!

15 Oct, 2018 | 00:01h | UTC

1 – WHO recommendations: non-clinical interventions to reduce unnecessary caesarean sections – World Health Organization (free PDF)

News Release: New WHO guidance on non-clinical interventions specifically designed to reduce unnecessary caesarean sections (free)

Related Cochrane Review: Non‐clinical interventions for reducing unnecessary caesarean section (free review and summary)

2 – Series: Optimising caesarean section use – The Lancet (free articles and commentaries, registration required)

Commentaries: Caesarean section use has almost doubled globally since 2000 – The Lancet (free) AND C-section births rise rapidly to more than 20 percent worldwide – Reuters (free) AND Rate Of C-Sections Is Rising At An ‘Alarming’ Rate, Report Says – NPR (free) AND C-section deliveries nearly doubled worldwide since 2000, study finds – CNN (free) AND C-section births surge to ‘alarming’ rates worldwide – study – BBC (free)

3 – A blueprint for the primary prevention of cancer: Targeting established, modifiable risk factors – CA: A Cancer Journal for Clinicians (free)

Commentary: Comprehensive report says tobacco control must be highest priority in cancer control – American Cancer Society (free)

4 – Analysis: Treatment burden should be included in clinical practice guidelines – The BMJ (free for a limited period)

5 – Opinion: Professional Societies Should Abstain From Authorship of Guidelines and Disease Definition Statements – Circulation: Cardiovascular Quality and Outcomes (free)

Commentaries: Professional Societies, Clinical Specialists, and Guidelines – Circulation: Cardiovascular Quality and Outcomes (free) AND Turn Cardiology Guidelines Over to Outsiders – MedPage Today (free registration required)

John Ioannidis, MD. “questioned whether cardiovascular guidelines “homogenize biased, collective, and organized ignorance” through use of predominantly “insider” experts as authors.” (from MedPage Today)

6 – Diagnosis and management of non-dialysis chronic kidney disease in ambulatory care: a systematic review of clinical practice guidelines – BMC Nephrology (free)

7 – KAAACI Evidence-Based Clinical Practice Guidelines for Chronic Cough in Adults and Children in Korea – Allergy, Asthma & Immunology Research (free)

Related: Managing Patients with Chronic Cough (free CHEST guidelines on the subject)

8 – Supplement: Digital Health and Health Systems of the Future – Global Health: Science and Practice (free articles)

Source: International Health Policies Newsletter

9 – Association of Mechanical Bowel Preparation and Oral Antibiotics Before Elective Colorectal Surgery With Surgical Site Infection: A Network Meta-analysis – JAMA Network Open (free)

Invited Commentary: When Will the Surgical Community Acknowledge the Evidence Regarding Prophylaxis With Oral Antibiotics for Scheduled Colorectal Operations? (free)

“Bowel Preparation and Oral Antibiotics Before Elective Colorectal Surgery. Once again the combination of oral antibiotic and oral mechanical cathartic bowel preparation yields the lowest rates of surgical site infections” (via @SWexner see Tweet)

10 – Unapproved Pharmaceutical Ingredients Included in Dietary Supplements Associated With US Food and Drug Administration Warnings – JAMA Network Open (free)

Editorial: The FDA and Adulterated Supplements—Dereliction of Duty – JAMA Network Open (free)

Commentaries: Nearly 800 dietary supplements contained unapproved drug ingredients, study finds – CNN (free) AND No Wonder It Works So Well – NPR (free) AND Hundreds of Dietary Supplements Are Tainted with Prescription Drugs – Scientific American (free) AND Hundreds of health, weight loss products contain unapproved ingredients: Study – UPI (free) AND Some dietary supplements contain potentially harmful drugs – Reuters (free)

CDC Report: Current Tobacco Smoking, Quit Attempts, and Knowledge About Harm in 28 Countries

16 Oct, 2018 | 21:22h | UTC

Current Tobacco Smoking, Quit Attempts, and Knowledge About Smoking Risks Among Persons Aged ≥15 Years — Global Adult Tobacco Survey, 28 Countries, 2008–2016 – Centers for Disease Control and Prevention (free)

How to Prevent Brain-Sapping Delirium in the ICU

12 Oct, 2018 | 01:50h | UTC

How To Prevent Brain-Sapping Delirium In The ICU – NPR (free text and podcast)

Review: What Treatments are Effective for Common Cold in Adults and Children?

12 Oct, 2018 | 01:51h | UTC

What treatments are effective for common cold in adults and children? – The BMJ (free review and infographic)

Commentaries: What works for treating children’s colds? – BBC (free) AND Doctors should steer young children away from decongestants – OnMedica (free)

Perspective: The Approach to Predictive Medicine that is Taking Genomics Research by Storm

12 Oct, 2018 | 01:49h | UTC

The approach to predictive medicine that is taking genomics research by storm – Nature (free)

“Polygenic risk scores represent a giant leap for gene-based diagnostic tests. Here’s why they’re still so controversial.”

Correspondence: Real-Time Patient–Provider Video Telemedicine Integrated with Clinical Care

12 Oct, 2018 | 01:49h | UTC

Real-Time Patient–Provider Video Telemedicine Integrated with Clinical Care – New England Journal of Medicine (free)

Environmental Noise Guidelines for the European Region

12 Oct, 2018 | 01:43h | UTC

Environmental Noise Guidelines for the European Region (2018) – World Health Organization (free PDF)

Commentary: Noise: The other pollution hurting our health – CNN (free)

Review: A New Vaccine for Shingles

12 Oct, 2018 | 01:44h | UTC

Shingrix: A New Vaccine for Shingles – Therapeutics Initiative (free)

“Need to vaccinate 31 people to prevent one instance of HZ; Need to vaccinate 358 people to prevent one instance on post herpetic neuralgia” (via @amtejani)

Consensus Statement: Management of Cutaneous Adverse Events in Patients on Targeted Anticancer Therapies and Immunotherapies

12 Oct, 2018 | 01:42h | UTC

Clinical management of cutaneous adverse events in patients on targeted anticancer therapies and immunotherapies: a national consensus statement by the Spanish Academy of Dermatology and Venereology and the Spanish Society of Medical Oncology – Clinical and Translational Oncology (free)

Evidence-Based Analysis: Venous Thromboembolism Prophylaxis May Cause More Harm than Benefit

12 Oct, 2018 | 01:45h | UTC

Venous thromboembolism prophylaxis may cause more harm than benefit: an evidence-based analysis of Canadian and international guidelines – Thrombosis Journal (free) (via @amtejani)

Fri, October 12 – 10 Stories of The Day!

12 Oct, 2018 | 00:01h | UTC

1 – Review: What treatments are effective for common cold in adults and children? – The BMJ (free review and infographic)

Commentaries: What works for treating children’s colds? – BBC (free) AND Doctors should steer young children away from decongestants – OnMedica (free)

2 – How To Prevent Brain-Sapping Delirium In The ICU – NPR (free text and podcast)

3 – Correspondence: Real-Time Patient–Provider Video Telemedicine Integrated with Clinical Care – New England Journal of Medicine (free)

4 – Perspective: The approach to predictive medicine that is taking genomics research by storm – Nature (free)

“Polygenic risk scores represent a giant leap for gene-based diagnostic tests. Here’s why they’re still so controversial.”

5 – Review: Venous thromboembolism prophylaxis may cause more harm than benefit: an evidence-based analysis of Canadian and international guidelines – Thrombosis Journal (free) (via @amtejani)

6 – Review: A New Vaccine for Shingles – Therapeutics Initiative (free)

“Need to vaccinate 31 people to prevent one instance of HZ; Need to vaccinate 358 people to prevent one instance on post herpetic neuralgia” (via @amtejani)

7 – Environmental Noise Guidelines for the European Region (2018) – World Health Organization (free PDF)

Commentary: Noise: The other pollution hurting our health – CNN (free)

8 – Clinical management of cutaneous adverse events in patients on targeted anticancer therapies and immunotherapies: a national consensus statement by the Spanish Academy of Dermatology and Venereology and the Spanish Society of Medical Oncology – Clinical and Translational Oncology (free)

9 – Effectiveness of the Stand More AT (SMArT) Work intervention: cluster randomised controlled trial – The BMJ (free)

Editorial: Reducing sedentary behaviour in the workplace (free)

Commentaries: Standing-desk workers ‘less tired, more engaged’ – BBC (free) AND Sit-stand desks may improve job performance, psychological health – UPI (free)

10 – Association of Unrecognized Myocardial Infarction With Long-term Outcomes in Community-Dwelling Older Adults: The ICELAND MI Study – JAMA (free for a limited period)

Commentaries: Silent Infarcts Have Similar Mortality Over 10 Years as Clinically Recognized MI – TCTMD (free) AND Association of Unrecognized MI With Long-Term Outcomes – American College of Cardiology (free)

Related Study: Silent Myocardial Infarction and Long-Term Risk of Heart Failure (link to abstract and commentaries)