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Review: Side Effects of Long‐Term Proton Pump Inhibitor Use

2 Nov, 2018 | 03:40h | UTC

Side Effects of Long‐Term Proton Pump Inhibitor Use: A Review – Basic & Clinical Pharmacology & Toxicology (free)

 


Systematic Review: Prophylactic Antibiotic Therapy for COPD

2 Nov, 2018 | 03:36h | UTC

Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD) – Cochrane Library (free)

Summary: Preventative antibiotic therapy for people with COPD – Cochrane Library (free)

“Use of continuous and intermittent prophylactic antibiotics results in a clinically significant benefit in reducing exacerbations in COPD patients.”

 


Cohort Study: BMI of 21-25kg/m2 Linked to Lowest Risk of Dying

2 Nov, 2018 | 03:38h | UTC

Association of BMI with overall and cause-specific mortality: a population-based cohort study of 3·6 million adults in the UK – The Lancet Diabetes & Endocrinology (free)

Commentaries: The association between BMI and mortality: implications for obesity prevention – The Lancet Diabetes & Endocrinology (free) AND BMI of 21-25kg/m2 linked to lowest risk of dying from cancer and heart disease – London School of Hygiene & Tropical Medicine (free) AND Being too fat or too thin ‘can cost four years of life’ – BBC (free)

 


Review: Management of Cancer-Therapy-Induced LV Dysfunction

2 Nov, 2018 | 03:34h | UTC

Management of Cancer-Therapy-Induced LV Dysfunction: Can the Guidelines Help? – American College of Cardiology (free) (via @md_arianemacedo)

Related: Cardio-Onco-Hematology in Clinical Practice (series of reviews and guidelines on the subject)

 


Systematic Review: Effectiveness of Plant-Based Diets in the Management of Type 2 Diabetes

2 Nov, 2018 | 03:37h | UTC

Effectiveness of plant-based diets in promoting well-being in the management of type 2 diabetes: a systematic review – BMJ Open Diabetes Research & Care (free)

Commentaries: Expert reaction to study looking at plant based or vegan diets and type 2 diabetes – Science Media Centre (free) AND Vegan diet linked to better diabetes control and wellbeing – OnMedica (free)

 


Study: Targeted Neurotechnology Restores Walking in Humans with Spinal Cord Injury

2 Nov, 2018 | 03:35h | UTC

Targeted neurotechnology restores walking in humans with spinal cord injury – Nature (free)

Editorial: Paralysed people walk again after spinal-cord stimulation (free)

Commentaries: Spinal implant helps three paralysed men walk again – BBC (free) AND Once Paralyzed, Three Men Take Steps Again With Spinal Implant – The New York Times (10 articles per month are free)

 


Payment Designed for People: Introducing the Primary Care Outcomes Model

2 Nov, 2018 | 03:32h | UTC

Payment Designed for People: Introducing the Primary Care Outcomes Model – NEJM Catalyst (free)

 


Study: Antibiotic and Acid-Suppression Medications During Early Childhood are Associated with Obesity

2 Nov, 2018 | 03:32h | UTC

Antibiotic and acid-suppression medications during early childhood are associated with obesity – Gut (free)

Related Study: Early Antibiotic Exposure and Weight Outcomes in Young Children – Pediatrics (free)

Commentaries: Expert reaction to antibiotic and antacid use in early childhood and risk of obesity – Science Media Centre (free) AND Antibiotic Exposure in Early Life Tied to Slightly Higher Obesity Risk – NEJM Journal Watch (free) AND Antibiotics, H2RAs and PPIs linked to child obesity – OnMedica (free) AND Two studies tie early antibiotic exposure to increased obesity risk – CIDRAP (free)

 


Study: Short Interpregnancy Intervals are Associated with Increased Risks for Adverse Pregnancy Outcomes

2 Nov, 2018 | 03:31h | UTC

Association of Short Interpregnancy Interval With Pregnancy Outcomes According to Maternal Age – JAMA Internal Medicine (free for a limited period)

Commentaries: Balancing the Risks and Desires for Pregnancy in Older Mothers: Increasing Morbidity, Declining Fertility – JAMA Internal Medicine (free for a limited period) AND Women ‘should leave at least a year between pregnancies’ – NHS Choices (free) AND Waiting a year between pregnancies lowers health risks, study says – CNN (free) AND Study: Do Even Older Moms Have To Wait 18 Months Between Pregnancies? – CommonHealth (free)

 


Study: Financial Conflicts of Interest Among Authors of Clinical Guidelines

2 Nov, 2018 | 03:28h | UTC

Prevalence of Financial Conflicts of Interest Among Authors of Clinical Guidelines Related to High-Revenue Medications – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: More Than Half of Physician Guideline Authors for Expensive Medications Have Undeclared Conflicts of Interest – MedicalResearch.com (free) AND Many Clinical Guideline Authors Have Undeclared Payments – Medical Health News (free)

 


Perspective: Unpublished Medical Research ‘a threat to public health’

2 Nov, 2018 | 03:23h | UTC

Unpublished medical research ‘a threat to public health’ – BBC (free)

 


Meta-Analysis: Cannabinoids for the Treatment of Chronic Noncancer Pain Conditions

2 Nov, 2018 | 03:29h | UTC

Cannabis and cannabinoids for the treatment of people with chronic noncancer pain conditions: a systematic review and meta-analysis of controlled and observational studies – Pain (free)

“It seems unlikely that cannabinoids are highly effective medicines for chronic noncancer pain conditions.”

 


Guidelines for Blunt Cerebrovascular Injury

2 Nov, 2018 | 03:21h | UTC

Best practice guidelines for blunt cerebrovascular injury (BCVI) – Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine (free)

 


Randomized Trial: Oral Curcumin in Elective Abdominal Aortic Aneurysm Repair

2 Nov, 2018 | 03:19h | UTC

Oral curcumin in elective abdominal aortic aneurysm repair: a multicentre randomized controlled trial – Canadian Medical Association Journal (free)

Editorial: Take turmeric with a grain of salt (free)

Commentary: Oral curcumin shows no benefit in reducing inflammation following vascular surgery – Canadian Medical Association Journal (free)

 


Deep Learning for MR Angiography: Automated Detection of Cerebral Aneurysms

2 Nov, 2018 | 03:20h | UTC

Deep Learning for MR Angiography: Automated Detection of Cerebral Aneurysms – Radiology (free) (@EricTopol)

 


The Safe Food Imperative: Accelerating Progress in Low- and Middle-Income Countries

2 Nov, 2018 | 03:18h | UTC

Book: The Safe Food Imperative: Accelerating Progress in Low- and Middle-Income Countries – The World Bank (free PDF)

 


Perspective: Surgical Value — Beyond Bundled Payments

2 Nov, 2018 | 03:22h | UTC

Surgical Value — Beyond Bundled Payments – NEJM Catalyst (free)

 


WHO Report: Air Pollution and Child Health

2 Nov, 2018 | 02:57h | UTC

Air pollution and child health: prescribing clean air – World Health Organization (free)

Commentaries: WHO says air pollution kills 600,000 children every year – Reuters (free) AND 90% of world’s children are breathing toxic air, WHO study finds – The Guardian (free)

Related: How air pollution is destroying our health – World Health Organization (free) AND Air pollution is the ‘new tobacco’, warns WHO head – The Guardian (free)

 


Modernized Classification of Cardiac Antiarrhythmic Drugs

2 Nov, 2018 | 02:55h | UTC

Modernized Classification of Cardiac Antiarrhythmic Drugs – Circulation (free)

 


Systematic Review: Interventions for Preventing Thromboembolic Events in Patients With Atrial Fibrillation

2 Nov, 2018 | 03:18h | UTC

Interventions for Preventing Thromboembolic Events in Patients With Atrial Fibrillation: A Systematic Review – Annals of Internal Medicine (free)

Commentary: DOACs in AF: Observational and Randomized Studies Don’t Always Agree – Medscape (free registration required)

 


Alex Nowbar’s research reviews – 29 October 2018

2 Nov, 2018 | 02:52h | UTC

Alex Nowbar’s research reviews, 29 October 2018 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

 


Cohort Study: Comparative Effectiveness and Safety of Bariatric Procedures for Weight Loss

2 Nov, 2018 | 02:56h | UTC

Comparative Effectiveness and Safety of Bariatric Procedures for Weight Loss: A PCORnet Cohort Study – Annals of Internal Medicine (free)

Commentaries: Effectiveness and Safety of Bariatric Procedures for Weight Loss – Annals of Internal Medicine (free) AND Gastric bypass surgery associated with greater weight loss in adults – Kaiser Permanente (free)

 


Systematic Review: Drug-Induced Interstitial Lung Disease

2 Nov, 2018 | 02:54h | UTC

Drug-Induced Interstitial Lung Disease: A Systematic Review – Journal of Clinical Medicine (free)

Commentary: Drugs’ side effects in lungs ‘more widespread than thought’ – The University of Manchester (free)

 


Perspective: What a Massive Database of Retracted Papers Reveals About Science Publishing’s ‘Death Penalty’

2 Nov, 2018 | 02:46h | UTC

What a massive database of retracted papers reveals about science publishing’s ‘death penalty’ – Science (free)

Related: A huge database of scientific retractions is live. That’s great for science. – VOX (free)

 


Cohort Study: Benefits and Harms of Antihypertensive Treatment in Low-Risk Patients With Mild Hypertension

2 Nov, 2018 | 02:44h | UTC

Benefits and Harms of Antihypertensive Treatment in Low-Risk Patients With Mild Hypertension – JAMA Internal Medicine (free for a limited period)

Commentaries: Treatment for moderately high blood pressure may be best saved for those at high risk – University of Cambridge (free) AND Study Questions Whether Treating Mild Hypertension Benefits Patients – NEJM Journal Watch (free)

 


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