Archives
Systematic Review: Effective Healthcare Cost-Containment Policies
16 Nov, 2018 | 01:03h | UTCEffective healthcare cost-containment policies: a systematic review – Health Policy (free)
“Ten Commandments” for the 2018 ESC/EACTS Guidelines on Myocardial Revascularization
16 Nov, 2018 | 00:58h | UTCSee Original Article: ESC/EACTS Guidelines on Myocardial Revascularization (free)
Systematic Review: Perioperative Alcohol Cessation Intervention for Postoperative Complications
16 Nov, 2018 | 01:01h | UTCPerioperative alcohol cessation intervention for postoperative complications – Cochrane Library (free)
Summary: Effects of perioperative alcohol cessation interventions on postoperative complications following surgery – Cochrane Library (free)
“Intensive alcohol cessation interventions offered for four to eight weeks to participants undergoing all types of surgical procedures to achieve complete alcohol cessation before surgery probably reduced the number of postoperative complications.”
Fri, November 16 – 10 Stories of The Day!
16 Nov, 2018 | 00:03h | UTC
3 – Perspective: Addressing Health-Related Misinformation on Social Media – JAMA (free for a limited period)
Commentary: Choosing Wisely: 5 Antibiotic Strategies to Avoid in Children – NEJM Journal Watch (free)
See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Commentaries: New diabetes drug may increase the risk of serious adverse events – Karolinska Institutet (free) AND SGLT2 Inhibitors Tied to Increased Risk for Amputation, Diabetic Ketoacidosis – NEJM Journal Watch (free) AND SGLT2 Inhibitor Amputation Risk Seen in Real-World Diabetes Study – Medscape (free registration required)
6 – Review: A time to fast – Science (free for a limited period) (via @EricTopol)
7 – Review: Interruption and Reversal of Direct Oral Anticoagulants in Preprocedural and Acute Settings – Journal of the American Board of Family Medicine (free)
Source: Medscape
8 – Acute mesenteric ischaemia: a pictorial review – Insights into Imaging (free)
Summary: Ways to help pregnant women avoid preterm birth – Cochrane Library (free)
Related: Post-Contrast Acute Kidney Injury (free reviews) AND Does contrast cause kidney injury? The evidence (free) AND Meta-Analysis: Acute Kidney Injury After Computed Tomography (link to abstract and commentaries)
Thu, November 15 – 10 Stories of The Day!
15 Nov, 2018 | 01:41h | UTC
“Prednisone treatment during the first 4 weeks after the initiation of ART for HIV infection resulted in a lower incidence of tuberculosis-associated immune reconstitution inflammatory syndrome than placebo, without evidence of an increased risk of severe infections or cancers.”
Commentaries: Expert reaction to study looking at low carbohydrate diets and weight maintenance – Science Media Centre (free) AND How a Low-Carb Diet Might Help You Maintain a Healthy Weight – The New York Times (10 articles per month are free) AND Low carb diets can help maintain weight loss by increasing number of calories burned – The BMJ (free)
3 – Increasing Safe Outpatient Management of Emergency Department Patients With Pulmonary Embolism: A Controlled Pragmatic Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Electronic Decision Support Facilitates Home Discharge of Some PE Patients From ER – MedicalResearch.com (free) AND EMR-Integrated Tool Lets More PE Patients Be Discharged from the ED – NEJM Journal Watch (free)
4 – Perspective: Benjamin Mazer: Are medical errors a huge problem that’s simple to fix? – The BMJ Opinion (free)
6 – Review: Neuroinfections caused by fungi – Infection (free)
7 – Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild cognitive impairment – Cochrane Library (free)
“The evidence on vitamin and mineral supplements as treatments for mild cognitive Impairment is very limited. “
8 – One Month of Cannabis Abstinence in Adolescents and Young Adults Is Associated With Improved Memory – Journal of Clinical Psychiatry (link to abstract – $ for full-text)
Commentaries: When Adolescents Give Up Pot, Their Cognition Quickly Improves – NPR (free) AND Stopping Cannabis Tied to Memory Improvements – NEJM Journal Watch (free)
9 – Long-term Survival following Multivessel Revascularization in Patients with Diabetes (FREEDOM Follow-On Study) – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Long-term FREEDOM: At Nearly 8 years, CABG Maintains Mortality Benefit Over PCI – TCTMD (free) AND FREEDOM Follow-On Study Findings Further Support CABG Over PCI in DM Patients With CAD – American College of Cardiology (free) AND AHA: CABG Still Better for Multivessel Disease in Diabetes – MedPage Today (free registration required)
10 – Antipsychotic drug use and pneumonia: Systematic review and meta-analysis – Journal of Psychopharmacology (link to abstract – $ for full-text)
Commentary: Antipsychotics May Increase Risk of Pneumonia, Meta-Analysis Suggests – Psychiatric News Alert (free)
“Although antipsychotic use was associated with a higher risk of pneumonia, the researchers stopped short of claiming causality, citing a lack of data from randomized, controlled trials and a failure of observational studies to control for relevant confounders like tobacco use and weight.” (from Psychiatric News Alert)
Wed, November 14 – 10 Stories of The Day!
14 Nov, 2018 | 00:01h | UTC
Editorials: Screening for Unhealthy Alcohol Use (free) AND Unhealthy Alcohol Use in Primary Care—The Elephant in the Examination Room (free)
Author Interview: USPSTF Recommendation: Screening and Interventions for Unhealthy Alcohol Use (free audio)
JAMA Patient Page: Screening and Counseling to Reduce Unhealthy Alcohol Use (free)
2 – 2018 IDSA Clinical Practice Guideline for the Management of Outpatient Parenteral Antimicrobial Therapy – Clinical Infectious Diseases (free) (via @ABsteward)
Commentary: Updated Guidelines Advise on Outpatient Parenteral Antimicrobial Therapy – Pharmacy Times (free) AND ID specialist input improves outcomes for outpatient parenteral antimicrobial therapy – Infectious Diseases Society of America (free)
Video Summary: Effect of a Pharmacist-Led Intervention on Inappropriate Prescriptions in Older Adults (free)
4 – Effect of Exercise Intervention on Functional Decline in Very Elderly Patients During Acute Hospitalization: A Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)
Commentaries: A Novel Exercise Intervention and Functional Status in Very Elderly Patients During Acute Hospitalization – JAMA Internal Medicine (free for a limited period) AND Exercise intervention benefits elderly in hospital – OnMedica (free)
Author Interview: Effect of Exercise Intervention on Functional Decline in Very Elderly Patients (free audio)
Videos: Morning Exercise Session (free) AND Evening Exercise Session (free) AND Balance and Gait Retraining Exercises (free)
5 – Top 8 Healthcare Predictions for 2019 – Forbes (free)
Source: Hospital Medicine Virtual Journal Club
8 – Review: Advances in optimizing the prescription of antibiotics in outpatient settings – The BMJ (free for a limited period)
9 – Clinical Report: Sport-Related Concussion in Children and Adolescents – Pediatrics (free)
Commentaries: Concussion management embraces earlier light exercise, earlier return to school – AAP News Release (free) AND Pediatrics Group Updates Guidance on Sports-Related Concussion – NEJM Journal Watch (free)
Commentaries: Public health burden of antimicrobial resistance in Europe – The Lancet Infectious Diseases (free) AND 33,000 people die every year due to infections with antibiotic-resistant bacteria – European Centre for Disease Prevention and Control (ECDC) (free) AND European study: 33,000 deaths a year from resistant infections – CIDRAP (free)
Guideline Synopsis: Incidental Pulmonary Nodules Detected on CT Images
9 Nov, 2018 | 03:00h | UTCIncidental Pulmonary Nodules Detected on CT Images – JAMA (free)
Tue, November 13 – 10 Stories of The Day!
13 Nov, 2018 | 00:01h | UTC
1 – The Physical Activity Guidelines for Americans – JAMA (free)
Editorial: New Physical Activity Guidelines: A Call to Activity for Clinicians and Patients (free)
Video Summary: Physical Activity Guidelines for Americans, 2nd Edition (free)
Commentaries: New Physical Activity Guidelines Urge Americans: Move More, Sit Less – NPR (free) AND HHS Releases Physical Activity Guidelines for Americans, 2nd edition – U.S. Department of Health & Human Services (free)
Commentaries: Stopping medication for heart failure with improved ejection fraction – The Lancet (free) AND Remission, Not Cure: No Weaning Off Meds for Dilated Cardiomyopathy Patients, Says TRED-HF – TCTMD (free) AND Drug Withdrawal Inadvisable in ‘Recovered’ Dilated Cardiomyopathy – Medscape (free registration required)
Commentaries: Endoscopic Vein-Graft Harvest for CABG Associated With Similar MACE, Less Pain vs Open Procedure: REGROUP – TCTMD (free) AND AHA: Endoscopic Vein-Graft Harvesting Redeems Itself in CABG – MedPage Today (free)
4 – Perspective: Getting Rid of Stupid Stuff – New England Journal of Medicine (free)
5 – Alex Nowbar’s research reviews, 12 November 2018 – The BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.
6 – Last Month in Oncology with Dr. Bishal Gyawali – The Health Care Blog (free)
Commentary: WHO uncovers big national variations in antibiotics consumption – Reuters (free)
9 – SGLT2 inhibitors for primary and secondary prevention of cardiovascular and renal outcomes in type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials – The Lancet (link to abstract – $ for full-text)
Commentary: SGLT2 Inhibitors and CV and Renal Outcomes in Type 2 Diabetes – American College of Cardiology (free)
10 – Risk of Malignant Ovarian Cancer Based on Ultrasonography Findings in a Large Unselected Population – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Most simple ovarian cysts require no treatment, surveillance – UPI (free) AND Less surveillance needed for simple ovarian cysts – University of California, San Francisco (free)
“New study finds that simple cysts should be considered normal and ignored” (from The University of California)
Mon, November 12 – 10 Stories of The Day!
12 Nov, 2018 | 00:01h | UTC
#AHA2018 – Highlights from the AHA Scientific Sessions 2018
1 – Global Burden of Disease Study 2017 – The Lancet (8 free articles)
See also: Infographics with GBD 2017 Study Highlights – Institute for Health Metrics and Evaluation (all free) AND Updated GBD Compare Visualization Tool – Institute for Health Metrics and Evaluation (free resource)
“All eight Global Burden of Disease 2017 papers providing 38 billion estimates of 359 diseases & injuries & 84 risk factors in 195 countries & territories” (via @TheLancet see Tweet)
2 – #AHA2018 – 2018 AHA/ACC Guideline on the Management of Blood Cholesterol – Circulation – A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines (free PDF)
Summary: 2018 ACC/AHA Multisociety Guideline on the Management of Blood Cholesterol – American College of Cardiology (free)
See also: Cholesterol Guideline Hub (free resources)
3 – #AHA2018 – Use of Risk Assessment Tools to Guide Decision-Making in the Primary Prevention of Atherosclerotic Cardiovascular Disease – A Special Report From the American Heart Association and American College of Cardiology (free PDF)
Summary: Use of Risk Assessment Tools to Guide Decision-Making in ASCVD Prevention – American College of Cardiology (free)
4 – #AHA2018 – Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease – New England Journal of Medicine (free)
Editorial: VITAL Signs for Dietary Supplementation to Prevent Cancer and Heart Disease (free)
Commentaries: Vitamin D And Fish Oil Supplements Mostly Disappoint In Long-Awaited Research Results – NPR (free) AND Fish Oil And Vitamin D Pills No Guard Against Cancer Or Serious Heart Trouble – Kaiser Health News (free)
5 – #AHA2018 – Marine n−3 Fatty Acids and Prevention of Cardiovascular Disease and Cancer – New England Journal of Medicine (free)
Commentaries: Vitamin D, omega-3 supplements do not prevent cancer or heart disease, study says – CNN (free) AND Vitamin D and Fish Oils Are Ineffective for Preventing Cancer and Heart Disease – The New York Times (10 articles per month are free)
Related Systematic Review: Omega-3 fatty Acids for the Prevention of Cardiovascular Disease (free review and commentaries)
6 – #AHA2018 – Amarin’s Fish-Oil-Derived Drug Shows Great Promise — With Big Caveats – Forbes (free) (via @cardiobrief)
Original Article: Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia – New England Journal of Medicine (free)
“what seriously bothered five of the six cardiologists I spoke to was that the mineral oil had not behaved as a placebo at all.”
7 – Effective healthcare cost-containment policies: a systematic review – Health Policy (free)
8 – Perioperative alcohol cessation intervention for postoperative complications – Cochrane Library (free)
Summary: Effects of perioperative alcohol cessation interventions on postoperative complications following surgery – Cochrane Library (free)
“Intensive alcohol cessation interventions offered for four to eight weeks to participants undergoing all types of surgical procedures to achieve complete alcohol cessation before surgery probably reduced the number of postoperative complications.”
See Original Article: ESC/EACTS Guidelines on Myocardial Revascularization (free)
WHO Guideline: Management of Physical Health Conditions in Adults with Severe Mental Disorders
9 Nov, 2018 | 03:02h | UTCGuideline: Management of physical health conditions in adults with severe mental disorders – World Health Organization (free PDF)
News Release: WHO guidelines: Management of physical health conditions in adults with severe mental disorders (free)
WHO Video: Improving the physical health of people with severe mental disorders (free)
Randomized Trial: New Single-Dose Oral Drug for Treatment of Gonorrhea
9 Nov, 2018 | 02:56h | UTCSingle-Dose Zoliflodacin (ETX0914) for Treatment of Urogenital Gonorrhea – New England Journal of Medicine (link to abstract – $ for full-text)
Related Perspective: Neisseria gonorrhoeae — Rising Infection Rates, Dwindling Treatment Options – New England Journal of Medicine (free)
Commentaries: Novel antibiotic shows promise in treatment of uncomplicated gonorrhea – NIH News Release (free) AND Experimental treatment appears effective against gonorrhea in small study – STAT (free) AND Single Dose of New Oral Antibiotic Cures Most Gonorrhea – Medscape (free registration required)
Randomized Trial: Triple-Drug Treatment for Lymphatic Filariasis
9 Nov, 2018 | 02:58h | UTCA Trial of a Triple-Drug Treatment for Lymphatic Filariasis – New England Journal of Medicine (free)
Editorial: Advancing toward the Elimination of Lymphatic Filariasis (free)
Commentary: Triple-Drug Therapy Superior to Two Drugs for Treating Lymphatic Filariasis – NEJM Journal Watch (free)
Randomized Trial: Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome
9 Nov, 2018 | 02:55h | UTCCommentaries: Among heart attack survivors, drug reduces chances of second heart attack or stroke – University of Colorado Anschutz Medical Campus (free) AND Alirocumab Linked to Lower Risk for Recurrent Ischemic CV Events – NEJM Journal Watch (free)
“An estimated 49 patients would need to be treated for 4 years to prevent one CV event.” (from NEJM Journal Watch)
Review: Gastroesophageal Reflux Disease, Functional Dyspepsia and Irritable Bowel Syndrome
9 Nov, 2018 | 02:53h | UTC
Debate: Could AI Make Doctors Obsolete?
9 Nov, 2018 | 02:51h | UTCHead To Head: Could artificial intelligence make doctors obsolete? – The BMJ (free)
Commentaries: Could machines using artificial intelligence make doctors obsolete? – The BMJ (free) AND Stop hyping artificial intelligence—patients will always need human doctors – The BMJ (free)
Study: Artificial Intelligence may Predict Alzheimer’s Years Before Diagnosis
9 Nov, 2018 | 02:50h | UTCA Deep Learning Model to Predict a Diagnosis of Alzheimer Disease by Using 18F-FDG PET of the Brain – Radiology (free for a limited period)
Commentaries: Artificial intelligence predicts Alzheimer’s years before diagnosis – Radiology Society of North America (free) AND Expert reaction to study looking at AI technology, brain imaging and Alzheimer’s disease detection – Science Media Centre (free) AND AI May Detect Alzheimer’s Years Before Diagnosis – Medscape (free registration required)
Meta-Analysis: Triple Therapy in the Management of COPD
9 Nov, 2018 | 02:46h | UTCCommentary: Triple Therapy for COPD Tied to Fewer Exacerbations, More Pneumonia – NEJM Journal Watch (free)
Perspective: Why Doctors Hate Their Computers
9 Nov, 2018 | 02:42h | UTCWhy Doctors Hate Their Computers – The New Yorker (free)
“Digitization promises to make medical care easier and more efficient. But are screens coming between doctors and patients?”
In Win for Open Access, Two Major Funders Won’t Cover Publishing in Hybrid Journals
9 Nov, 2018 | 02:40h | UTCIn win for open access, two major funders won’t cover publishing in hybrid journals – Science (free)
See also: Wellcome and Gates join bold European open-access plan – Nature (free) AND Wellcome is updating its open access policy (free) AND Big funders back plan for instant free access to journals, but researchers say it is risky for science – Science|Business (free)
Related: cOAlition S: Making Open Access a Reality by 2020 (free Statement and commentaries)
WHO Guide: Basic Emergency Care
9 Nov, 2018 | 02:44h | UTCBasic Emergency Care: approach to the acutely ill and injured – World Health Organization (free PDF)
Study: Health-Motivated Taxes on Red and Processed Meat
9 Nov, 2018 | 02:36h | UTCCommentaries: Should there be a tax on red meat? – BBC (free) AND Taxing red meat would save many lives, research shows – The Guardian (free)
Related: To improve global health, tax the things that are killing us – Financial Times (free policies, articles and commentaries) AND Policy lessons from health taxes (free research and commentaries) AND Fiscal policies for diet and the prevention of noncommunicable diseases – World Health Organization (free) AND The Lancet taskforce on NCDs and economics (free series and commentaries)
Podcast: Battle of the Heart Societies: Who Is Right–the US or Europe–Regarding How to Manage Hypertension?
9 Nov, 2018 | 02:27h | UTCRelated: Impact of the Discordance Between Blood Pressure Guidelines (free perspective and commentaries)
Study: Link Between Vaccines and Allergies Dismissed
9 Nov, 2018 | 02:32h | UTCCommentary: Link between vaccines and allergies dismissed – Karolinska Institutet (free)
2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay
9 Nov, 2018 | 02:36h | UTCSee also: Executive Summary (free) AND Summary form AAC (free) AND Bradycardia Guideline Hub (free resources)
Guideline Summary: Prevention, Diagnosis and Treatment of Hospital-Acquired Pneumonia in ICU
9 Nov, 2018 | 02:20h | UTCRelated: Summary of the international clinical guidelines for the management of hospital-acquired and ventilator-acquired pneumonia (free) AND International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia (free) AND Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society (free)