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Randomized Trial: Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome

30 Nov, 2018 | 02:49h | UTC

Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome – New England Journal of Medicine (link to abstract – $ for full-text)

Video Summary: Alirocumab and CV Events after Acute Coronary Syndrome (free)

 


Study: Youngest in Class More Likely to be Diagnosed with ADHD

30 Nov, 2018 | 02:50h | UTC

Attention Deficit–Hyperactivity Disorder and Month of School Enrollment – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: When starting school, younger children are more likely to be diagnosed with ADHD – Harvard Medical School (free) AND Youngest Children In A Class Are Most Likely To Get ADHD Diagnosis – NPR (free) AND Younger school entry could set stage for ADHD diagnosis – Associated Press (free)

Related: Systematic Review: Youngest in Class More Likely to be Diagnosed with ADHD (free study and commentaries)

 


Perspective: Is Our Constant Use of Digital Technologies Affecting our Brain Health?

30 Nov, 2018 | 02:46h | UTC

Is our constant use of digital technologies affecting our brain health? We asked 11 experts – VOX (free)

 


Global Burden of Pneumonia in Children Younger than 5 Years

30 Nov, 2018 | 02:44h | UTC

Global, regional, and national estimates of pneumonia morbidity and mortality in children younger than 5 years between 2000 and 2015: a systematic analysis – The Lancet Global Health (free)

Invited Commentary: Global childhood pneumonia: the good news, the bad news, and the way ahead (free)

 


Europe’s Bold Open-Access Plan Detailed

30 Nov, 2018 | 02:47h | UTC

Plan S: From Principles to Implementation. cOAlition S Releases Implementation Guidance on Plan S (free)

Commentary: Funders flesh out details of Europe’s bold open-access plan (free)

Related: In Win for Open Access, Two Major Funders Won’t Cover Publishing in Hybrid Journals (free commentaries) AND cOAlition S: Making Open Access a Reality by 2020 (free Statement and commentaries)

 


WHO Housing and Health Guidelines

30 Nov, 2018 | 02:45h | UTC

WHO Housing and health guidelines – World Health Organization (free)

 


Survey Snapshot: What Would Accelerate the Adoption of Value-Based Care?

30 Nov, 2018 | 02:36h | UTC

Survey Snapshot: What Would Accelerate the Adoption of Value-Based Care? – NEJM Catalyst (free)

 


Study: Screenning for Colorectal Cancer with FOBT Only Effective in Men

30 Nov, 2018 | 02:41h | UTC

Sex differences in faecal occult blood test screening for colorectal cancer – British Journal of Surgery (free)

Commentaries: Screen­ing for colorectal can­cer spares male pa­tients from in­tense treat­ments – University of Helsinki (free) AND FOBT Colorectal Cancer Screening Only Effective in Men – Medscape (free registration required)

 


Global Burden of Alzheimer’s Disease and Other Dementias

30 Nov, 2018 | 02:43h | UTC

Global, regional, and national burden of Alzheimer’s disease and other dementias, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 – The Lancet Neurology (free)

Invited Commentary: Statistics on the burden of dementia: need for stronger data – The Lancet (free)

“In 2016, globally, 43·8 million individuals lived with dementia, increased from 20.2 million in 1990; dementia was the fifth leading cause of death globally (2·4 million) and more women than men had dementia” (via @TheLancet see Tweet with infographic)

 


Review: Therapy and Management of Pneumocystis Jirovecii

30 Nov, 2018 | 02:39h | UTC

Therapy and Management of Pneumocystis jirovecii – Infection – Journal of Fungi (free)

This article belongs to the Special Issue Treatments for Fungal Infections (free reviews)

 


Study: Trazodone Associated Risks

30 Nov, 2018 | 02:40h | UTC

Comparative risk of harm associated with trazodone or atypical antipsychotic use in older adults with dementia: a retrospective cohort study – Canadian Medical Association Journal (free)

Commentaries: Study finds alternative to antipsychotic medication for seniors also has drawbacks – The Globe and Mail (free) AND Trazadone linked to more falls, major fractures in dementia patients – UPI (free) AND Trazadone associated with similar risk of falls and major fractures as antipsychotics in seniors with dementia – Canadian Medical Association Journal (free) AND Aggression in Dementia: Alternatives to Antipsychotics Also Have Side Effects – MedicalResearch.com (free)

 


Review: Arterial Thrombosis in Unusual Sites

30 Nov, 2018 | 02:38h | UTC

Arterial thrombosis in unusual sites: A practical review – European Journal of Haematology (free)

 


Study: Some Research May be Encouraging Ineffective Prescriptions

30 Nov, 2018 | 02:32h | UTC

Assessment of Pregabalin Postapproval Trials and the Suggestion of Efficacy for New Indications: A Systematic Review – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentary: Some research may be encouraging ineffective prescriptions, says new study – McGill University (free)

“Our point is not to condemn these individual trials. Instead, we are saying that—when you zoom out and look at what’s happening at the level of the forest—the trees begin to look less healthy.” (from McGill University)

 


Viewpoint: A Global Public Health Victory for Tobacco Plain-Packaging Laws in Australia

30 Nov, 2018 | 02:29h | UTC

A Global Public Health Victory for Tobacco Plain-Packaging Laws in Australia – JAMA Internal Medicine (free for a limited period)

 


Ten Simple Rules for Collaboratively Writing a Multi-Authored Paper

30 Nov, 2018 | 02:35h | UTC

Ten simple rules for collaboratively writing a multi-authored paper – PLOS Computational Biology (free) (via @Abraham_RMI)

 


Genome-Edited Baby Provokes International Outcry

30 Nov, 2018 | 02:02h | UTC

Genome-edited baby claim provokes international outcry – Nature (free)

See also: A Reckless and Needless Use of Gene-Editing on Human Embryos – The Atlantic (free) AND Chinese researcher claims first gene-edited babies – Associated Press (free) AND EXCLUSIVE: Chinese scientists are creating CRISPR babies – MIT Technology Review (free) AND Expert reaction to reports of the first genome edited baby – Science Media Centre (free) AND What we know — and what we don’t — about the claim of world’s first gene-edited babies – STAT (free)

 


Study Confirms Effectiveness of Fractional-Dose Yellow Fever Vaccination

30 Nov, 2018 | 02:28h | UTC

Long-Term Protection After Fractional-Dose Yellow Fever Vaccination: Follow-up Study of a Randomized, Controlled, Noninferiority Trial – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentary: Study affirms fractional dosing with yellow fever vaccine – CIDRAP (free)

Related: Fractional-Dose Yellow Fever Vaccination (free research and perspective)

 


NICE Guideline: Catheter-Associated Urinary Tract Infection

30 Nov, 2018 | 02:27h | UTC

Urinary tract infection (catheter-associated): antimicrobial prescribing – National Institute for Health and Care Excellence (free)

Related: NICE Antimicrobial Prescribing Guidelines (free guidelines and resources)

 


Guideline: Febrile Neutropenia in Adults with Solid Tumors

30 Nov, 2018 | 02:25h | UTC

SEOM clinical practice guideline: management and prevention of febrile neutropenia in adults with solid tumors (2018) – Clinical and Translational Oncology (free)

Related: Guideline: Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy (free guidelines on the subject)

 


Investigation: The Implant Files

30 Nov, 2018 | 02:01h | UTC

Implant Files – The International Consortium of Investigative Journalists (free articles)

News Releases: Medical Devices Harm Patients Worldwide As Governments Fail On Safety (free) AND ICIJ publishes new investigation: the Implant Files (free) AND About The Implant Files Investigation (free)

Commentaries: How lobbying blocked European safety checks for dangerous medical implants – The BMJ (free) AND Revealed: faulty medical implants harm patients around world – The Guardian (free) AND Medical device rules need ‘drastic change’ to protect patients – BBC (free)

 


Podcast: STIs: Syphilis, Gonorrhea and Chlamydia

30 Nov, 2018 | 01:59h | UTC

#127 STIs: Syphilis, Gonorrhea and Chlamydia – The Curbsiders Internal Medicine Podcast (free)

 


AAP Guideline: Maintenance Intravenous Fluids in Children

30 Nov, 2018 | 02:00h | UTC

Clinical Practice Guideline: Maintenance Intravenous Fluids in Children – Pediatrics (free)

News Release: Evidence-based guideline recommends isotonic solutions for children who need intravenous fluids – AAP News (free)

 


Acute Liver Failure: Evidence-Based Evaluation and Management

30 Nov, 2018 | 01:55h | UTC

Acute Liver Failure: Evidence-Based Evaluation and Management – emDocs (free)

 


Ann Robinson’s Research Reviews – 26 November 2018

30 Nov, 2018 | 01:57h | UTC

Ann Robinson’s research reviews, 26 November 2018 – The BMJ Opinion (free)

Ann Robinson reviews the latest research from the top medical journals.

 


Guideline Synopsis: Diagnosis and Management of Nonalcoholic Liver Disease

30 Nov, 2018 | 01:56h | UTC

Diagnosis and Management of Nonalcoholic Liver Disease – JAMA (free for a limited period)

 


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