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Guideline: Pathophysiology and Management of Opioid-induced Constipation

27 Feb, 2019 | 00:38h | UTC

Pathophysiology and management of opioid-induced constipation: European expert consensus statement – United European Gastroenterology Journal (free)

Related Guideline: American Gastroenterological Association Institute Guideline on the Medical Management of Opioid-Induced Constipation (free guideline and commentaries)

 


Tue, February 26 – 10 Stories of The Day!

26 Feb, 2019 | 04:38h | UTC

 

1 – Management of sepsis in neutropenic cancer patients: 2018 guidelines from the Infectious Diseases Working Party (AGIHO) and Intensive Care Working Party (iCHOP) of the German Society of Hematology and Medical Oncology (DGHO) – Annals of Hematology (free)

Related Guidelines: SEOM clinical practice guideline: management and prevention of febrile neutropenia in adults with solid tumors (2018) – Clinical and Translational Oncology (free) AND Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy: American Society of Clinical Oncology and Infectious Diseases Society of America Clinical Practice Guideline Update – Journal of Clinical Oncology (free) AND Diagnosis and empirical treatment of fever of unknown origin (FUO) in adult neutropenic patients: guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO) (free) AND Management of febrile neutropaenia: ESMO Clinical Practice Guidelines (free) AND Guideline for the Management of Fever and Neutropenia in Children With Cancer and Hematopoietic Stem-Cell Transplantation Recipients: 2017 Update (free)

 

2 – AGA Clinical Practice Update on Surgical Risk Assessment and Perioperative Management in Cirrhosis: Expert Review – Clinical Gastroenterology and Hepatology (free)

 

3 – Distracted Driving, Visual Inattention, and Crash Risk Among Teenage Drivers – American Journal of Preventive Medicine (free for a limited period)

Commentary: Reaching for objects while driving may raise teen crash risk nearly sevenfold – NIH News Releases (free)

 

4 – Withholding or withdrawing invasive interventions may not accelerate time to death among dying ICU patients – PLOS One (free)

Commentary: Avoiding invasive treatment in dying patients may not shorten lifespan – Stanford Medicine (free)

 

5 – Limitation of Life-Sustaining Care in the Critically Ill: A Systematic Review of the Literature – Journal of Hospital Medicine (free PDF for a limited period)

Related: Dying with Dignity in the Intensive Care Unit – New England Journal of Medicine (free) AND Palliative care in intensive care units: why, where, what, who, when, how – BMC Anesthesiology (free) AND Ten key points about ICU palliative care – Intensive Care Medicine (free) AND Guidelines for the withdrawal of life-sustaining measures – Intensive Care Medicine (free) AND End-of-life in the ICU: moving from ‘withdrawal of care’ to a palliative care, patient-centred approach – British Journal of Anaesthesia (free) AND New concepts in palliative care in the intensive care unit – Revista Brasileira de Terapia Intensiva (free) AND The Changing Role of Palliative Care in the ICU – Critical Care Medicine (free)

 

6 – Clinical Guidelines on Chronic Rhinosinusitis in Children – Current Allergy and Asthma Reports (free for a limited period)

Note: if the above link is paywalled, try this one

Related Guideline: Clinical Consensus Statement: Pediatric Chronic Rhinosinusitis – Otolaryngology–Head and Neck Surgery (free)

 

7 – Stress Testing Versus CT Angiography in Patients With Diabetes and Suspected Coronary Artery Disease – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentary: CT Angiography Bests Functional Testing in Diabetic Patients With Chest Pain: PROMISE – TCTMD (free)

 

8 – Nuances to the Management of Febrile Patients: Non-Infectious Causes of Fever – emDocs (free)

Related: Pyrexia: aetiology in the ICU – Critical Care (free)

 

9 – Measuring Hospital-Acquired Complications Associated With Low-Value Care – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentary: Low-value procedures harm patients, consume hospital resources – HealthExec (free)

 

10 – Performance Characteristics of Fecal Immunochemical Tests for Colorectal Cancer and Advanced Adenomatous Polyps: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Annual noninvasive stool test effective for colon cancer screening – Regenstrief Institute (free) AND Annual FIT home stool test effective for CRC screening rates – American College of Physicians (free) AND Meta-Analysis Adds Support for FIT for Colorectal Cancer Screening – NEJM Journal Watch (free) AND One-Time FIT Adequately Detects CRC but Not Advanced Adenomas – MedPage Today (free registration required)

 


Systematic Review and Guidelines on the Evaluation and Treatment of Patients with Thoracolumbar Spine Trauma

27 Feb, 2019 | 00:34h | UTC

Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on the Evaluation and Treatment of Patients with Thoracolumbar Spine Trauma – Neurosurgery (free articles)

– Executive Summary

– Classification of Injury

– Radiological Evaluation

– Neurological Assessment

– Pharmacological Treatment

– Prophylaxis and Treatment of Thromboembolic Events

– Hemodynamic Management

– Nonoperative Care

– Operative Versus Nonoperative Treatment

– Timing of Surgical Intervention

– Surgical Approaches

– Novel Surgical Strategies

 


AGA Clinical Practice Update on Surgical Risk Assessment and Perioperative Management in Cirrhosis

26 Feb, 2019 | 02:31h | UTC

AGA Clinical Practice Update on Surgical Risk Assessment and Perioperative Management in Cirrhosis: Expert Review – Clinical Gastroenterology and Hepatology (free)

 


Guideline: Management of Sepsis in Neutropenic Cancer Patients

26 Feb, 2019 | 02:32h | UTC

Management of sepsis in neutropenic cancer patients: 2018 guidelines from the Infectious Diseases Working Party (AGIHO) and Intensive Care Working Party (iCHOP) of the German Society of Hematology and Medical Oncology (DGHO) – Annals of Hematology (free)

Related Guidelines: SEOM clinical practice guideline: management and prevention of febrile neutropenia in adults with solid tumors (2018) – Clinical and Translational Oncology (free) AND Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy: American Society of Clinical Oncology and Infectious Diseases Society of America Clinical Practice Guideline Update – Journal of Clinical Oncology (free) AND Diagnosis and empirical treatment of fever of unknown origin (FUO) in adult neutropenic patients: guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO) (free) AND Management of febrile neutropaenia: ESMO Clinical Practice Guidelines (free) AND Guideline for the Management of Fever and Neutropenia in Children With Cancer and Hematopoietic Stem-Cell Transplantation Recipients: 2017 Update (free)

 


Withholding or Withdrawing Invasive Interventions May Not Accelerate Time to Death Among Dying ICU Patients

26 Feb, 2019 | 02:28h | UTC

Withholding or withdrawing invasive interventions may not accelerate time to death among dying ICU patients – PLOS One (free)

Commentary: Avoiding invasive treatment in dying patients may not shorten lifespan – Stanford Medicine (free)

 


Distracted Driving, Visual Inattention, and Crash Risk Among Teenage Drivers

26 Feb, 2019 | 02:29h | UTC

Distracted Driving, Visual Inattention, and Crash Risk Among Teenage Drivers – American Journal of Preventive Medicine (free for a limited period)

Commentary: Reaching for objects while driving may raise teen crash risk nearly sevenfold – NIH News Releases (free)

 


Clinical Guidelines on Chronic Rhinosinusitis in Children

26 Feb, 2019 | 02:23h | UTC

Clinical Guidelines on Chronic Rhinosinusitis in Children – Current Allergy and Asthma Reports (free for a limited period)

Note: if the above link is paywalled, try this one

Related Guideline: Clinical Consensus Statement: Pediatric Chronic Rhinosinusitis – Otolaryngology–Head and Neck Surgery (free)

 


Systematic Review: Limitation of Life-Sustaining Care in the Critically Ill

26 Feb, 2019 | 02:25h | UTC

Limitation of Life-Sustaining Care in the Critically Ill: A Systematic Review of the Literature – Journal of Hospital Medicine (free PDF for a limited period)

Related: Dying with Dignity in the Intensive Care Unit – New England Journal of Medicine (free) AND Palliative care in intensive care units: why, where, what, who, when, how – BMC Anesthesiology (free) AND Ten key points about ICU palliative care – Intensive Care Medicine (free) AND Guidelines for the withdrawal of life-sustaining measures – Intensive Care Medicine (free) AND End-of-life in the ICU: moving from ‘withdrawal of care’ to a palliative care, patient-centred approach – British Journal of Anaesthesia (free) AND New concepts in palliative care in the intensive care unit – Revista Brasileira de Terapia Intensiva (free) AND The Changing Role of Palliative Care in the ICU – Critical Care Medicine (free)

 


Study: Stress Testing Versus CT Angiography in Patients with Diabetes and Suspected Coronary Artery Disease

26 Feb, 2019 | 02:21h | UTC

Stress Testing Versus CT Angiography in Patients With Diabetes and Suspected Coronary Artery Disease – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentary: CT Angiography Bests Functional Testing in Diabetic Patients With Chest Pain: PROMISE – TCTMD (free)

 


Meta-analysis: Performance of Fecal Immunochemical Tests for Colorectal Cancer Screening

26 Feb, 2019 | 02:15h | UTC

Performance Characteristics of Fecal Immunochemical Tests for Colorectal Cancer and Advanced Adenomatous Polyps: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Annual noninvasive stool test effective for colon cancer screening – Regenstrief Institute (free) AND Annual FIT home stool test effective for CRC screening rates – American College of Physicians (free) AND Meta-Analysis Adds Support for FIT for Colorectal Cancer Screening – NEJM Journal Watch (free) AND One-Time FIT Adequately Detects CRC but Not Advanced Adenomas – MedPage Today (free registration required)

 


Measuring Hospital-Acquired Complications Associated with Low-Value Care

26 Feb, 2019 | 02:17h | UTC

Measuring Hospital-Acquired Complications Associated With Low-Value Care – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentary: Low-value procedures harm patients, consume hospital resources – HealthExec (free)

 


Nuances to the Management of Febrile Patients: Non-Infectious Causes of Fever

26 Feb, 2019 | 02:19h | UTC

Nuances to the Management of Febrile Patients: Non-Infectious Causes of Fever – emDocs (free)

Related: Pyrexia: aetiology in the ICU – Critical Care (free)

 


Guideline: Diagnosis and Management of Acute Lower Gastrointestinal Bleeding

25 Feb, 2019 | 01:20h | UTC

Diagnosis and management of acute lower gastrointestinal bleeding: guidelines from the British Society of Gastroenterology – Gut (free)

Related: ACG Clinical Guideline: Management of Patients With Acute Lower Gastrointestinal Bleeding (free)

 


Mon, February 25 – 10 Stories of The Day!

25 Feb, 2019 | 01:32h | UTC

 

1 – Diagnosis and management of acute lower gastrointestinal bleeding: guidelines from the British Society of Gastroenterology – Gut (free)

Related: ACG Clinical Guideline: Management of Patients With Acute Lower Gastrointestinal Bleeding (free)

 

2 – Copenhagen Consensus statement 2019: physical activity and ageing – British Journal of Sports Medicine (free)

 

3 – Best Practices for Evaluation and Treatment of Agitated Children and Adolescents (BETA) in the Emergency Department: Consensus Statement of the American Association for Emergency Psychiatry – West Journal of Emergency Medicine (free PDF)

Related Guideline: Evaluation and Management of Children and Adolescents With Acute Mental Health or Behavioral Problems. Part I: Common Clinical Challenges of Patients With Mental Health and/or Behavioral Emergencies – Pediatrics (free)

 

4 – Association Between Push-up Exercise Capacity and Future Cardiovascular Events Among Active Adult Men – JAMA Network Open (free)

Commentaries: Push-up capacity linked with lower incidence of cardiovascular disease events among men – Harvard T.H. Chan School of Public Health (free) AND Struggling to do push-ups? You may be at risk of heart disease – NHS (free) AND How Many Push-Ups Can You Do? It May Be a Good Predictor of Heart Health – The New York Times (10 articles per month are free)

 

5 – FDA adds Boxed Warning for increased risk of death with gout medicine Uloric (febuxostat) – U.S. Food & Drug Administration (free)

Commentaries: FDA Adds Boxed Warning About CV Risks to Gout Drug Febuxostat – TCTMD (free) AND FDA: Gout Drug Raises Death Risk – MedPage Today (free)

Related Research: Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (free study and commentaries)

 

6 – Updates in Management and Timing of Dialysis in Acute Kidney Injury – Journal of Hospital Medicine (free PDF for a limited period)

Related Research: Early vs. Delayed Dialysis in Acute Kidney Injury (link to abstract and commentary)

 

7 – Pharmacological treatments for generalised anxiety disorder: a systematic review and network meta-analysis – The Lancet (link to abstract – $ for full-text)

Commentary: Pharmacotherapy for Generalized Anxiety: An Update – NEJM Journal Watch (free for a limited period)

 

8 – Strategy for a globally coordinated response to a priority neglected tropical disease: Snakebite envenoming – PLOS Neglected Tropical Diseases (free)

News Release: New WHO strategy aims to halve the global impact of snakebite – The University of Melbourne (free)

Related: Global Mapping of Vulnerability to Snakebite Envenoming (free study and commentaries) AND Why Are So Many People Still Dying from Snake Bites? (free) AND Snakebite finally makes a WHO list of top global health priorities (free) AND Snakebites Make The List Of ‘Neglected Tropical Diseases’ (free)

 

9 – Management of Cardiovascular Disease in Women With Breast Cancer – Circulation (free)

Related: AHA Scientific Statement on Cardio-Oncology (several guidelines on the subject)

 

10 – A Review of the Role of Breast Arterial Calcification for Cardiovascular Risk Stratification in Women – Circulation (free)

Commentary: Breast Calcifications May Hold Important Clues for CV Risk Stratification – TCTMD (free)

 


Best Practices for Evaluation and Treatment of Agitated Children and Adolescents in the Emergency Department

25 Feb, 2019 | 01:18h | UTC

Best Practices for Evaluation and Treatment of Agitated Children and Adolescents (BETA) in the Emergency Department: Consensus Statement of the American Association for Emergency Psychiatry – West Journal of Emergency Medicine (free PDF)

Related Guideline: Evaluation and Management of Children and Adolescents With Acute Mental Health or Behavioral Problems. Part I: Common Clinical Challenges of Patients With Mental Health and/or Behavioral Emergencies – Pediatrics (free)

 


Consensus Statement: Physical Activity and Ageing

25 Feb, 2019 | 01:19h | UTC

Copenhagen Consensus statement 2019: physical activity and ageing – British Journal of Sports Medicine (free)

 


Updates in Management and Timing of Dialysis in Acute Kidney Injury

25 Feb, 2019 | 01:14h | UTC

Updates in Management and Timing of Dialysis in Acute Kidney Injury – Journal of Hospital Medicine (free PDF for a limited period)

Related Research: Early vs. Delayed Dialysis in Acute Kidney Injury (link to abstract and commentary)

 


Cohort Study: Association Between Push-up Exercise Capacity and Future Cardiovascular Events

25 Feb, 2019 | 01:17h | UTC

Association Between Push-up Exercise Capacity and Future Cardiovascular Events Among Active Adult Men – JAMA Network Open (free)

Commentaries: Push-up capacity linked with lower incidence of cardiovascular disease events among men – Harvard T.H. Chan School of Public Health (free) AND Struggling to do push-ups? You may be at risk of heart disease – NHS (free) AND How Many Push-Ups Can You Do? It May Be a Good Predictor of Heart Health – The New York Times (10 articles per month are free)

 


FDA Adds Boxed Warning for Increased Risk of Death with Gout Medicine Febuxostat

25 Feb, 2019 | 01:15h | UTC

FDA adds Boxed Warning for increased risk of death with gout medicine Uloric (febuxostat) – U.S. Food & Drug Administration (free)

Commentaries: FDA Adds Boxed Warning About CV Risks to Gout Drug Febuxostat – TCTMD (free) AND FDA: Gout Drug Raises Death Risk – MedPage Today (free)

Related Research: Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (free study and commentaries)

 


Meta-Analysis: Pharmacological Treatments for Generalized Anxiety Disorder

25 Feb, 2019 | 01:11h | UTC

Pharmacological treatments for generalised anxiety disorder: a systematic review and network meta-analysis – The Lancet (link to abstract – $ for full-text)

Commentary: Pharmacotherapy for Generalized Anxiety: An Update – NEJM Journal Watch (free for a limited period)

 


Management of Cardiovascular Disease in Women With Breast Cancer

25 Feb, 2019 | 01:09h | UTC

Management of Cardiovascular Disease in Women With Breast Cancer – Circulation (free)

Related: AHA Scientific Statement on Cardio-Oncology (several guidelines on the subject)

 

Related Commentary on Twitter

 


New WHO Strategy Aims to Halve the Global Impact of Snakebite

25 Feb, 2019 | 01:10h | UTC

Strategy for a globally coordinated response to a priority neglected tropical disease: Snakebite envenoming – PLOS Neglected Tropical Diseases (free)

News Release: New WHO strategy aims to halve the global impact of snakebite – The University of Melbourne (free)

Related: Global Mapping of Vulnerability to Snakebite Envenoming (free study and commentaries) AND Why Are So Many People Still Dying from Snake Bites? (free) AND Snakebite finally makes a WHO list of top global health priorities (free) AND Snakebites Make The List Of ‘Neglected Tropical Diseases’ (free)

 


Review: Role of Breast Arterial Calcification for Cardiovascular Risk Stratification in Women

25 Feb, 2019 | 01:07h | UTC

A Review of the Role of Breast Arterial Calcification for Cardiovascular Risk Stratification in Women – Circulation (free)

Commentary: Breast Calcifications May Hold Important Clues for CV Risk Stratification – TCTMD (free)

 

Related Commentary on Twitter

 


Meta-Analysis: Increasing the Dose Intensity of Chemotherapy in Early Breast Cancer

25 Feb, 2019 | 01:02h | UTC

Increasing the dose intensity of chemotherapy by more frequent administration or sequential scheduling: a patient-level meta-analysis of 37 298 women with early breast cancer in 26 randomised trials – The Lancet (free)

Commentaries: Dose intensification of chemotherapy for early breast cancer in the age of de-escalation – The Lancet (free) AND Meta-analysis of Outcomes With Dose-Intense Adjuvant Chemotherapy in Early Breast Cancer – The ASCO Post (free)

 


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