Archives
BRAVO Registry | Brugada substrate ablation results in a significant reduction of ventricular fibrillation events
27 Mar, 2023 | 13:11h | UTCLong-Term Outcomes of Brugada Substrate Ablation: A Report from BRAVO (Brugada Ablation of VF Substrate Ongoing Multicenter Registry) – Circulation (free for a limited period)
Outcomes of ST elevation myocardial infarction in patients with cancer: a nationwide study
27 Mar, 2023 | 13:12h | UTCOutcomes of ST elevation myocardial infarction in patients with cancer: a nationwide study – European Heart Journal – Quality of Care and Clinical Outcomes (free for a limited period)
Commentary on Twitter
Cancer and #STEMI – a worrisome combination of higher short- and long-term mortality, and bleeding risk. https://t.co/kHvhGP0PBE #EHJQCCO #cardiotwitter @cpgale3 @diogoasantosfer pic.twitter.com/SfjyizoJvQ
— European Society of Cardiology Journals (@ESC_Journals) March 26, 2023
Phase 2b RCT | Efficacy and safety of PL-5 (Peceleganan) spray for wound infections
27 Mar, 2023 | 13:08h | UTC
Brief Review | Long-term outcomes of intensive care unit delirium
27 Mar, 2023 | 13:09h | UTCLong-term outcomes of intensive care unit delirium – Intensive Care Medicine
Commentary on Twitter
#ICU delirium
🏥 well described short-term effects: ⬆️ hospital mortality, MV duration, ICU/hospital LoS
📚 more recent findings related to long-term outcomes (≥ 6 months post-ICU)
How to mitigate this serious acute BI & its long-term burden? #FOAMcc
🖇️ https://t.co/kg5TIOmVHm pic.twitter.com/Hnbc1ISKnI— Intensive Care Medicine (@yourICM) March 25, 2023
M-A | The effect of curcumin supplementation on weight loss and anthropometric indices
27 Mar, 2023 | 13:04h | UTC
RCT | No reduction in parastomal hernia rate 3 years after stoma construction with prophylactic Mesh
27 Mar, 2023 | 13:07h | UTC
Review | Neoadjuvant therapy for pancreatic cancer
27 Mar, 2023 | 13:02h | UTCNeoadjuvant therapy for pancreatic cancer – Nature Reviews Clinical Oncology (free for a limited period)
RCT | Topical lidocaine or lidocaine/diltiazem ointment following rubber band ligation of hemorrhoids
27 Mar, 2023 | 13:05h | UTCTopical Lidocaine or Lidocaine/Diltiazem Ointment Following Rubber Band Ligation of Hemorrhoids: A Prospective Three-Armed Randomized Controlled Trial – Diseases of the Colon & Rectum (link to abstract – $ for full-text)
Phase 2 RCT | Semaglutide did not improve fibrosis in NASH-related cirrhosis
27 Mar, 2023 | 13:01h | UTCCommentary: Semaglutide Well-Tolerated, But Shows Lack of Improvement in Liver Fibrosis – HCP Live
Commentary on Twitter
New research – Loomba et al – Semaglutide 2·4 mg once weekly in patients with non-alcoholic steatohepatitis-related cirrhosis: a randomised, placebo-controlled phase 2 trialhttps://t.co/qkydKMpVfO#NASH #NAFLD #cirrhosis #gitwitter #livertwitter #medtwitter @DrLoomba pic.twitter.com/2A1dylSiq3
— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) March 17, 2023
Brief Review | Bronchodilators or inhaled corticosteroids for postinfectious cough
27 Mar, 2023 | 13:00h | UTCBronchodilators or inhaled corticosteroids for postinfectious cough – Canadian Family Physician
RCT | Rituximab is superior to azathioprine for maintenance of remission for patients with ANCA vasculitis and relapsing disease
27 Mar, 2023 | 12:57h | UTC
Review | Lung transplantation for COPD/pulmonary emphysema
27 Mar, 2023 | 12:58h | UTCLung transplantation for COPD/pulmonary emphysema – European Respiratory Review
Guidelines for neuroprognostication in comatose adult survivors of cardiac arrest
27 Mar, 2023 | 12:54h | UTC
Trends of randomized clinical trials citing prior systematic reviews, 2007-2021
27 Mar, 2023 | 12:56h | UTCTrends of Randomized Clinical Trials Citing Prior Systematic Reviews, 2007-2021 – JAMA Network Open
Invited Commentary: Should a Systematic Review Be Required in a Clinical Trial Report? Perhaps, But Not Yet – JAMA Network Open
Commentary on Twitter
The percentage of RCTs citing systematic reviews increased from 36% in 2007-8 to 72% since 2020. RCTs with ≥100 participants, nonindustry funders, and authors from high-income countries were more likely to cite systematic reviews. https://t.co/rMN7eEmkqD
— JAMA Network Open (@JAMANetworkOpen) March 23, 2023
Guidelines for neuroprognostication in adults with Guillain-Barré Syndrome
27 Mar, 2023 | 12:52h | UTCGuidelines for Neuroprognostication in Adults with Guillain–Barré Syndrome – Neurocritical Care
Study shows increased bleeding complications in ESKD patients undergoing AF ablation
24 Mar, 2023 | 13:09h | UTCSummary: The study analyzed 347 procedures in 307 patients with end-stage kidney disease (ESKD) undergoing atrial fibrillation (AF) catheter ablation in 12 referral centers in Japan.
Despite a vast majority of patients having subtherapeutic international normalized ratio (INR) values during the peri-procedural period, 35 patients (10%) experienced major complications, with the majority being major bleeding events (19 patients; 5.4%), including 11 cases of cardiac tamponade (3.2%). There were also two peri-procedural deaths (0.6%), both related to bleeding events. A pre-procedural INR value of 2.0 or higher was identified as the only independent predictor of major bleeding.
Current peri-procedural anticoagulation guidelines state that patients undergoing AF ablation should be under therapeutic anticoagulation throughout the peri-procedural period. The findings of this study suggest that these guidelines may not be appropriate for ESKD patients undergoing the procedure, and the role of peri-procedural anticoagulation in this population should be further investigated.
Commentary on Twitter
Peri-procedural anticoagulation in patients with end-stage kidney disease undergoing #afib ablation 👉 despite undertreatment with warfarin, the rate of haemorrhagic complications is high! https://t.co/3W8gEtZYdy#kidney #afib #anticoagulation #ablation #cardiotwitter #europace pic.twitter.com/vI27UeIpRf
— European Society of Cardiology Journals (@ESC_Journals) March 16, 2023
Review of noninvasive neuromonitoring modalities in children: EEG, qEEG
27 Mar, 2023 | 12:50h | UTCReview of Noninvasive Neuromonitoring Modalities in Children II: EEG, qEEG – Neurocritical Care (if the link is paywalled, try this one)
Epidural-related maternal fever: incidence, pathophysiology, outcomes, and management
24 Mar, 2023 | 13:07h | UTCEpidural-related maternal fever: incidence, pathophysiology, outcomes, and management – American Journal of Obstetrics & Gynecology (free for a limited period)
Commentary on Twitter
AJOG Expert Review in Labor: Epidural-related maternal fever: incidence, pathophysiology, outcomes and management – Proposed mechanisms of sterile inflammation resulting in epidural-related maternal fever https://t.co/iTaQTKBlc3 pic.twitter.com/z0yrxzoMlh
— AJOG (@AJOG_thegray) March 19, 2023
Review | Unapparent systemic effects of regional anticoagulation with citrate in continuous renal replacement therapy
24 Mar, 2023 | 13:04h | UTC
Consensus Paper | Connective tissue disease-associated pulmonary arterial hypertension
24 Mar, 2023 | 13:06h | UTC
Review | Navigating the new eating disorder landscape: atypical anorexia and avoidant/restrictive food intake disorder
24 Mar, 2023 | 13:03h | UTCPitfalls and Risks of “New Eating Disorders”: Let the Expert Speak! – Nutrients
Commentary: A review on two novel eating disorders – News Medical
M-A | Prevalence, imaging patterns and risk factors of interstitial lung disease in connective tissue disease
24 Mar, 2023 | 13:02h | UTC
Study shows there is little evidence of heightened pregnancy risks for IVF-conceived parents
24 Mar, 2023 | 12:53h | UTCNews Release: Little evidence that IVF conception heightens future pregnancy risks – BMJ Newsroom
Role of sleep in peripheral artery disease risk: Insights from cohort and mendelian randomization studies
24 Mar, 2023 | 13:01h | UTCNews Release: Short night-time sleep linked with nearly doubled risk of clogged leg arteries – European Society of Cardiology
Cohort Study | Functional recovery, symptoms, and quality of life 1 to 5 years after traumatic brain injury
24 Mar, 2023 | 12:52h | UTC