Archives
A Randomized Trial of Prophylactic Antibiotics for Miscarriage Surgery
14 Mar, 2019 | 01:00h | UTCA Randomized Trial of Prophylactic Antibiotics for Miscarriage Surgery – New England Journal of Medicine (free for a limited period)
Video Summary: Prophylactic Antibiotics before Miscarriage Surgery (free)
Commentaries: Research shines light on preventing infection after miscarriage – University of Birmingham (free) AND Antibiotics before miscarriage surgery not tied to fewer infections – CIDRAP (free)
Related Commentary on Twitter
Antibiotic prophylaxis before miscarriage surgery did not result in a significantly lower risk of pelvic infection, as defined by pragmatic broad criteria, than placebo. However, benefit was observed in a secondary analysis that defined pelvic infection by strict criteria.
— NEJM (@NEJM) March 13, 2019
Progress in Adolescent Health and Wellbeing: Tracking 12 Headline Indicators for 195 Countries and Territories
14 Mar, 2019 | 00:58h | UTCCommentaries: Improving adolescent health: an evidence-based call to action – The Lancet (free) AND Disease, violence and inequality threaten more adolescents worldwide than ever before – The Lancet (free) AND The world’s adolescents: large unmet needs and growing inequalities – University of Melbourne (free) AND Adolescent health, education needs unmet in many countries, study says – UPI (free)
Related Commentary on Twitter
First study to track progress in 12 indicators of #adolescenthealth in 195 countries, incl. risk factors & social issues impacting health, highlights slow pace of change in health, education & legal systems, leaving #adolescent needs unmet @LancetYouth https://t.co/UdM5owjI9Q pic.twitter.com/OPCTdF23kj
— The Lancet (@TheLancet) March 13, 2019
Trends in Cause-specific Mortality Among Children Aged 5–14 years in India, China, Brazil, and Mexico
14 Mar, 2019 | 00:55h | UTCCommentaries: Shedding light on a million annual deaths in mid-childhood – The Lancet (free) AND Most deaths in children aged 5 to 14 in India, China, Brazil, Mexico are preventable – St. Michael’s Hospital (free)
Related Commentary on Twitter
Most deaths that occurred between 2005 & 2016 in children aged 5–14 years in #India, #China, #Brazil & #Mexico arose from preventable or treatable conditions: finding from new analysis of nationally representative mortality studies @WHO @UofThttps://t.co/KfcylsWDu0 pic.twitter.com/A9n1kvhhtv
— The Lancet (@TheLancet) March 12, 2019
SIGN Guideline: Risk Reduction and Management of Delirium
14 Mar, 2019 | 00:52h | UTCRisk reduction and management of delirium – Scottish Intercollegiate Guidelines Network (SIGN) (free guideline and summary)
News Release: First delirium clinical guidelines for Scotland published on World Delirium Awareness Day (free)
EAN Guideline on Trigeminal Neuralgia
14 Mar, 2019 | 00:50h | UTCEAN guideline on trigeminal neuralgia – European Journal of Neurology (free PDF)
Review: Clinical Assessment of Peripheral Tissue Perfusion in Septic Shock
14 Mar, 2019 | 00:47h | UTCRelated Research: Randomized Trial: Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels in Patients with Septic Shock (link to abstract $ for full-text)
Ten Myths Around Open Scholarly Publishing
14 Mar, 2019 | 00:38h | UTCTen myths around open scholarly publishing – PeerJ Preprints (free PDF)
Related: UC Terminates Subscriptions with World’s Largest Scientific Publisher in Push for Open Access (several commentaries on the subject)
Special Issue: Infections in Solid Organ Transplantation Guidelines
14 Mar, 2019 | 00:35h | UTCInfections in Solid Organ Transplantation – Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice (free PDF articles)
– BK Polyomavirus in Solid Organ Transplantation
– Adenovirus in Solid Organ Transplant Recipients
– Mycobacterium tuberculosis Infections in Solid Organ Transplantation
– Nocardia Infections in Solid Organ Transplantation
– Urinary Tract Infections in Solid Organ Transplant Recipients
– Herpes Simplex Virus Infections in Solid Organ Transplantation
– RNA Respiratory Viral Infections in Solid Organ Transplant Recipients
– Interactions between Anti‐infective Agents and Immunosuppressants
– Travel Medicine, Transplant Tourism, and the Solid Organ Transplant Recipient
– Solid Organ Transplantation in the HIV‐Infected Patient
– Cytomegalovirus in Solid Organ Transplant Recipients
– Human Herpesvirus 6, 7 and 8 in Solid Organ Transplantation
– Strategies for Safe Living Following Solid Organ Transplantation
– Emerging Fungal Infections in Solid Organ Transplant Recipients
Pro/Con Debate: Should Asymptomatic Patients with Moderate-to-severe OSA be Treated?
14 Mar, 2019 | 00:43h | UTCPro: should asymptomatic patients with moderate-to-severe OSA be treated? – Breathe (free)
Con: should asymptomatic patients with moderate-to-severe OSA be treated? – Breathe (free)
Related: Obstructive Sleep Apnea in Cardiovascular Disease: A Review of the Literature and Proposed Multidisciplinary Clinical Management Strategy (free reviews) AND Positive airway pressure doesn’t reduce cardiovascular events and death in adults with sleep apnea (link to abstract and commentaries)
Wed, March 13 – 10 Stories of The Day!
13 Mar, 2019 | 06:15h | UTC
Commentaries: Air pollution causes 8.8 million extra early deaths a year – European Society of Cardiology (free) AND Air Pollution Causes 8.8 Million Extra Deaths a Year – U.S. News (free) AND Air pollution kills 8.8 million people per year globally, study says – UPI (free)
Related: 9 out of 10 people worldwide breathe polluted air, but more countries are taking action – World Health Organization (free) AND The cost of a polluted environment: 1.7 million child deaths a year, says WHO – World Health Organization (free) AND Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution: an analysis of data from the Global Burden of Diseases Study 2015 – The Lancet (free) AND Death in the Air: Air Pollution Costs Money and Lives – World Bank (free infographic and report)
2 – Evidence evolving on aspirin as prevention – ACP Internist (free)
Related: Randomized Trial: Aspirin for Primary Prevention of Cardiovascular Disease (link to abstract and commentaries) AND Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes (link to abstract and commentaries) AND Randomized Trial: Effect of Aspirin on All-Cause Mortality in the Healthy Elderly (link to abstract and commentaries) AND Meta-Analysis: Association of Aspirin Use for Primary Prevention with Cardiovascular Events and Bleeding Events (link to abstract and commentaries)
“In patients who have not had a prior cardiovascular event, aspirin’s protective effects are modest and may not necessarily outweigh its potential downsides (namely, risk of bleeding and hemorrhagic stroke).”
4 – Italy bans unvaccinated children from school – BBC (free)
5 – Randomized Trial of Four Treatment Approaches for Actinic Keratosis – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Comparison of Four Treatments for Actinic Keratosis – NEJM Resident 360 (free) AND Actinic keratosis: fluorouracil cream tops other options in randomized trial – Univadis (free registration required)
6 – Podcast: #142 Cirrhosis TIPS for Acute Complications – The Curbsiders Internal Medicine Podcast (free)
See also: Episode List
See also: Largest ever HIV prevention study delivers sobering message – Science (free)
Commentary: The global burden of stroke: persistent and disabling – The Lancet Neurology (free)
Commentary: Navigating Allosensitization in Heart Transplant Candidates and Recipients – American Heart Association (free)
Top Ten Things to Know: Sensitization in Heart Transplantation: Emerging Knowledge – American Heart Association (free)
Cardiovascular Disease Burden from Ambient Air Pollution Reassessed
13 Mar, 2019 | 06:07h | UTCCommentaries: Air pollution causes 8.8 million extra early deaths a year – European Society of Cardiology (free) AND Air Pollution Causes 8.8 Million Extra Deaths a Year – U.S. News (free) AND Air pollution kills 8.8 million people per year globally, study says – UPI (free)
Related: 9 out of 10 people worldwide breathe polluted air, but more countries are taking action – World Health Organization (free) AND The cost of a polluted environment: 1.7 million child deaths a year, says WHO – World Health Organization (free) AND Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution: an analysis of data from the Global Burden of Diseases Study 2015 – The Lancet (free) AND Death in the Air: Air Pollution Costs Money and Lives – World Bank (free infographic and report)
Italy Bans Unvaccinated Children From School
13 Mar, 2019 | 05:48h | UTCItaly bans unvaccinated children from school – BBC (free)
Evidence Evolving on Aspirin as Prevention
13 Mar, 2019 | 06:04h | UTCEvidence evolving on aspirin as prevention – ACP Internist (free)
Related: Randomized Trial: Aspirin for Primary Prevention of Cardiovascular Disease (link to abstract and commentaries) AND Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes (link to abstract and commentaries) AND Randomized Trial: Effect of Aspirin on All-Cause Mortality in the Healthy Elderly (link to abstract and commentaries) AND Meta-Analysis: Association of Aspirin Use for Primary Prevention with Cardiovascular Events and Bleeding Events (link to abstract and commentaries)
“In patients who have not had a prior cardiovascular event, aspirin’s protective effects are modest and may not necessarily outweigh its potential downsides (namely, risk of bleeding and hemorrhagic stroke).”
Randomized Trial of Four Treatment Approaches for Actinic Keratosis
13 Mar, 2019 | 05:46h | UTCRandomized Trial of Four Treatment Approaches for Actinic Keratosis – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Comparison of Four Treatments for Actinic Keratosis – NEJM Resident 360 (free) AND Actinic keratosis: fluorouracil cream tops other options in randomized trial – Univadis (free registration required)
Low Back Pain, a Comprehensive Review: Pathophysiology, Diagnosis, and Treatment
13 Mar, 2019 | 05:52h | UTC
Podcast: Cirrhosis TIPS for Acute Complications
13 Mar, 2019 | 03:45h | UTC#142 Cirrhosis TIPS for Acute Complications – The Curbsiders Internal Medicine Podcast (free)
See also: Episode List
Perioperative Care of Cannabis Users: A Comprehensive Review of Pharmacological and Anesthetic Considerations
13 Mar, 2019 | 03:38h | UTC
‘Test and Treat’ Reduces new HIV Infections by a Third
13 Mar, 2019 | 03:34h | UTCSee also: Largest ever HIV prevention study delivers sobering message – Science (free)
AHA Scientific Statement: Sensitization in Heart Transplantation
13 Mar, 2019 | 03:18h | UTCCommentary: Navigating Allosensitization in Heart Transplant Candidates and Recipients – American Heart Association (free)
Top Ten Things to Know: Sensitization in Heart Transplantation: Emerging Knowledge – American Heart Association (free)
Global, Regional, and National Burden of Stroke
13 Mar, 2019 | 03:23h | UTCCommentary: The global burden of stroke: persistent and disabling – The Lancet Neurology (free)
Related Commentary on Twitter
The latest study in @TheLancetNeuro series, "Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016" was published today. Read more: https://t.co/nYpXQOG1n6 pic.twitter.com/5bccA8B2Bs
— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) March 12, 2019
Randomized Trial: Thyroidectomy vs. Medical Management for Euthyroid Patients with Hashimoto Disease and Persisting Symptoms
12 Mar, 2019 | 17:28h | UTCThyroidectomy Versus Medical Management for Euthyroid Patients With Hashimoto Disease and Persisting Symptoms: A Randomized Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Thyroidectomy Seems to Improve Quality of Life in Hashimoto Disease – NEJM Journal Watch (free) AND Thyroidectomy more effective than medication for Hashimoto disease with persisting symptoms – 2 Minute Medicine (free)
“Results are applicable only to a subgroup of patients with Hashimoto disease, and follow-up was limited to 18 months.”
Systematic Review: Epidural Analgesia for Adults Undergoing Cardiac Surgery with or Without Cardiopulmonary Bypass
12 Mar, 2019 | 13:29h | UTCEpidural analgesia for adults undergoing cardiac surgery with or without cardiopulmonary bypass – Cochrane Library (free)
Summary: Epidural analgesia for heart surgery with or without the heart lung machine in adults – Cochrane Library (free)
“Compared with systemic analgesia, epidural analgesia may reduce the risk of myocardial infarction, respiratory depression, and atrial fibrillation / atrial flutter, as well as the duration of tracheal intubation and pain, in adults undergoing cardiac surgery.”
Brazilian Guidelines for the Management of Psychomotor Agitation
12 Mar, 2019 | 13:15h | UTCBrazilian guidelines for the management of psychomotor agitation – Brazilian Journal of Psychiatry (free articles)
Part 1. Non-pharmacological approach
Part 2. Pharmacological approach
Consensus on Noninvasive CNS Neuromodulation for Chronic Pain Management
12 Mar, 2019 | 13:06h | UTC
Consensus Statement: Management of Adult Patients with Traumatic Brain Injury Receiving Oral Anticoagulant Therapy
12 Mar, 2019 | 13:01h | UTC