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Meta-Analysis: Surgical Management vs. Non-surgical Management of Rib Fractures in Chest Trauma

30 Mar, 2019 | 17:03h | UTC

Surgical management versus non-surgical management of rib fractures in chest trauma: a systematic review and meta-analysis – Journal of Cardiothoracic Surgery (free)

 


Meta-Analysis: Corticosteroids Increase Mortality in Patients with Influenza Pneumonia

29 Mar, 2019 | 07:51h | UTC

The effect of corticosteroids on mortality of patients with influenza pneumonia: a systematic review and meta-analysis – Critical Care (free)

 


Fri, March 29 – 10 Stories of The Day!

29 Mar, 2019 | 07:57h | UTC

 

1 – Lung cancer: diagnosis and management – National Institute for Health and Care Excellence (free)

Related Quality Standard: Lung cancer in adults – National Institute for Health and Care Excellence (free)

 

2 – The European guideline on management of major bleeding and coagulopathy following trauma: fifth edition – Critical Care (free)

 

3 – The effect of corticosteroids on mortality of patients with influenza pneumonia: a systematic review and meta-analysis – Critical Care (free)

 

4 – Comparative efficacy and acceptability of non-surgical brain stimulation for the acute treatment of major depressive episodes in adults: systematic review and network meta-analysis – The BMJ (free)

Commentary: Consider non-surgical brain stimulation for severe depression, say experts – The BMJ (free)

 

5 – Cefazolin versus anti-staphylococcal penicillins for the treatment of patients with Staphylococcus aureus bacteremia: a systematic review and meta-analysis – Clinical Microbiology and Infection (free)

 

6 – Systematic Review: Adverse Effects of Pharmacological Treatments of Major Depression in Older Adults – Agency for Healthcare Research and Quality (free)

See also: Full Report (free PDF) AND Evidence Summary (free PDF)

 

7 – Standards for the diagnosis and management of complex regional pain syndrome: Results of a European Pain Federation task force – European Journal of Pain (free)

Related: Complex regional pain syndrome in adults (2nd edition) – UK guidelines for diagnosis, referral and management in primary and secondary care 2018 – Royal College of Physicians (free PDF)

 

8 – Direct healthcare costs of sedentary behaviour in the UK – Journal of Epidemiology & Community Practice (free)

Commentaries: Does prolonged sitting really kill 70,000 people a year in the UK? – NHS Choices (free) AND Queen’s research shows sedentary lifestyle linked to 70,000 deaths per year in the UK – Queen’s University Belfast (free) AND Expert reaction to study looking at sitting down and death – Science Media Centre (free)

 

9 – A comparison of gender-linked population cancer risks between alcohol and tobacco: how many cigarettes are there in a bottle of wine? – BMC Public Health (free)

Commentaries: How many cigarettes are there in a bottle of wine? – BMC Series Blog (free) AND Cigarettes and alcohol: should we be communicating cancer risk in terms of cigarettes smoked? – Cancer Research UK (free)

 

10 – Global expansion and redistribution of Aedes-borne virus transmission risk with climate change – PLOS Neglected Tropical Diseases (free)

Commentaries: CHART: Where Disease-Carrying Mosquitoes Will Go In The Future – NPR (free) AND Mosquito-spread diseases may endanger millions in new places due to climate change – The Guardian (free)

Related: Climate Change — A Health Emergency (free reports and commentaries on the subject)

 


NICE Guideline: Lung Cancer

29 Mar, 2019 | 07:54h | UTC

Lung cancer: diagnosis and management – National Institute for Health and Care Excellence (free)

Related Quality standard: Lung cancer in adults – National Institute for Health and Care Excellence (free)

 


European Guideline on Management of Major Bleeding and Coagulopathy Following Trauma

29 Mar, 2019 | 07:53h | UTC

The European guideline on management of major bleeding and coagulopathy following trauma: fifth edition – Critical Care (free)

 


Meta-Analysis: Non-surgical Brain Stimulation for Major Depressive Episodes

29 Mar, 2019 | 07:49h | UTC

Comparative efficacy and acceptability of non-surgical brain stimulation for the acute treatment of major depressive episodes in adults: systematic review and network meta-analysis – The BMJ (free)

Commentary: Consider non-surgical brain stimulation for severe depression, say experts – The BMJ (free)

 


Meta-Analysis: Cefazolin vs. Anti-staphylococcal Penicillins for the Treatment of Staphylococcus aureus Bacteremia

29 Mar, 2019 | 07:47h | UTC

Cefazolin versus anti-staphylococcal penicillins for the treatment of patients with Staphylococcus aureus bacteremia: a systematic review and meta-analysis – Clinical Microbiology and Infection (free)

 


Systematic Review: Adverse Effects of Pharmacological Treatments of Major Depression in Older Adults

29 Mar, 2019 | 07:45h | UTC

Systematic Review: Adverse Effects of Pharmacological Treatments of Major Depression in Older Adults – Agency for Healthcare Research and Quality (free)

See also: Full Report (free PDF) AND Evidence Summary (free PDF)

 


Study: Direct Healthcare Costs of Sedentary Behavior

29 Mar, 2019 | 07:25h | UTC

Direct healthcare costs of sedentary behaviour in the UK – Journal of Epidemiology & Community Practice (free)

Commentaries: Does prolonged sitting really kill 70,000 people a year in the UK? – NHS Choices (free) AND Queen’s research shows sedentary lifestyle linked to 70,000 deaths per year in the UK – Queen’s University Belfast (free) AND Expert reaction to study looking at sitting down and death – Science Media Centre (free)

 


Study: A Comparison of Cancer Risks Between Alcohol and Tobacco

29 Mar, 2019 | 07:22h | UTC

A comparison of gender-linked population cancer risks between alcohol and tobacco: how many cigarettes are there in a bottle of wine? – BMC Public Health (free)

Commentaries: How many cigarettes are there in a bottle of wine? – BMC Series Blog (free) AND Cigarettes and alcohol: should we be communicating cancer risk in terms of cigarettes smoked? – Cancer Research UK (free)

 


Position Paper: Diagnosis and Management of Complex Regional Pain Syndrome

29 Mar, 2019 | 07:36h | UTC

Standards for the diagnosis and management of complex regional pain syndrome: Results of a European Pain Federation task force – European Journal of Pain (free)

Related: Complex regional pain syndrome in adults (2nd edition) – UK guidelines for diagnosis, referral and management in primary and secondary care 2018 – Royal College of Physicians (free PDF)

 


Study: Climate Change will Lead to a Global Expansion of Aedes-borne Virus Infections

29 Mar, 2019 | 06:56h | UTC

Global expansion and redistribution of Aedes-borne virus transmission risk with climate change – PLOS Neglected Tropical Diseases (free)

Commentaries: CHART: Where Disease-Carrying Mosquitoes Will Go In The Future – NPR (free) AND Mosquito-spread diseases may endanger millions in new places due to climate change – The Guardian (free)

Related: Climate Change — A Health Emergency (free reports and commentaries on the subject)

 

Relate Commentary on Twitter (interactive chart – click for more)

 


Thu, March 28 – 10 Stories of The Day!

28 Mar, 2019 | 07:42h | UTC

 

1 – Contemporary Diagnosis and Management of Patients With Myocardial Infarction in the Absence of Obstructive Coronary Artery Disease: A Scientific Statement From the American Heart Association (free PDF)

Related: Review: Management of Myocardial Infarction with Nonobstructive Coronary Arteries (free) AND Cohort Study: Presentation, Clinical Profile, and Prognosis of Young Patients with Myocardial Infarction with Nonobstructive Coronary Arteries (free)

 

2 – Combined Surgery and Extensive Intraoperative Peritoneal Lavage vs Surgery Alone for Treatment of Locally Advanced Gastric Cancer: The SEIPLUS Randomized Clinical Trial – JAMA Surgery (free for a limited period)

Invited Commentary: Extensive Intraoperative Peritoneal Lavage to Prevent Metastases From Gastric Cancer: The Elegance of Simplicity (free)

Commentary: High Marks for EIPL After Gastric Ca Surgery: No deaths, fewer complications, less pain with extended intraperitoneal lavage – MedPage Today (free registration required)

 

3 – Overall Survival with Fulvestrant plus Anastrozole in Metastatic Breast Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Gain in Survival with Fulvestrant plus Anastrozole in Metastatic Breast Cancer – MedicalResearch.com (free) AND Fulvestrant plus anastrozole extends lives of women with advanced HR+ breast cancer – SWOG (free)

 

4 – In-Hospital Cardiac Arrest: A Review – JAMA (free for a limited period)

 

5 – Imaging in trauma in limited-resource settings: A literature review – African Journal of Emergency Medicine (free)

 

6 – The measles virus was down and out. Now it’s primed for a comeback – STAT (free)

 

7 – One gram a day of omega-3 supplements does not reduce the risk of cancer or cardiovascular disease – NIHR Signal (free)

Original Article: Randomized Trial: Marine n−3 Fatty Acids and Prevention of Cardiovascular Disease and Cancer (free)

Related Meta-Analysis: Omega-3 Fatty Acid Supplements Don’t Reduce Cardiovascular Risk (free article and commentary)

Related Systematic Review: Omega-3 fatty Acids for the Prevention of Cardiovascular Disease (free review and commentaries)

 

8 – Adenosine deaminase for diagnosis of tuberculous pleural effusion: A systematic review and meta-analysis – PLOS One (free)

 

9 – Prostate Imaging Reporting & Data System – American College of Radiology (free PDF)

News Release: PI-RADS Steering Committee Releases New Version of the Prostate Imaging Reporting and Data System (v2.1 2019) – American College of Radiology (free)

 

10 – Proton Pump Inhibitors and Risk of Acute and Chronic Kidney Disease: A Retrospective Cohort Study – Pharmacotherapy (free)

Commentary: Study: Research ties common heartburn medications to kidney disease and failure – University at Buffalo (free)

Related: Meta-Analysis of Observational Studies: Proton Pump Inhibitors are Associated with Increased Risk of Kidney Disease (link to abstract – $ for full-text) AND Proton Pump Inhibitors: Review of Emerging Concerns (free reviews) AND Deprescribing Proton Pump Inhibitors (free guidelines and reviews)

 


Randomized Trial: Surgery + Extensive Intraoperative Peritoneal Lavage vs. Surgery Alone for Treatment of Locally Advanced Gastric Cancer

28 Mar, 2019 | 07:35h | UTC

Combined Surgery and Extensive Intraoperative Peritoneal Lavage vs Surgery Alone for Treatment of Locally Advanced Gastric Cancer: The SEIPLUS Randomized Clinical Trial – JAMA Surgery (free for a limited period)

Invited Commentary: Extensive Intraoperative Peritoneal Lavage to Prevent Metastases From Gastric Cancer: The Elegance of Simplicity (free)

Commentary: High Marks for EIPL After Gastric Ca Surgery: No deaths, fewer complications, less pain with extended intraperitoneal lavage – MedPage Today (free registration required)

 


AHA Scientific Statement: Management of Myocardial Infarction in the Absence of Obstructive Coronary Artery Disease

28 Mar, 2019 | 07:37h | UTC

Contemporary Diagnosis and Management of Patients With Myocardial Infarction in the Absence of Obstructive Coronary Artery Disease: A Scientific Statement From the American Heart Association (free PDF)

Related: Review: Management of Myocardial Infarction with Nonobstructive Coronary Arteries (free) AND Cohort Study: Presentation, Clinical Profile, and Prognosis of Young Patients with Myocardial Infarction with Nonobstructive Coronary Arteries (free)

 

Related Commentary on Twitter

 


In-Hospital Cardiac Arrest: A Review

28 Mar, 2019 | 07:31h | UTC

In-Hospital Cardiac Arrest: A Review – JAMA (free for a limited period)

 


Randomized Trial: Treatments for Hormone Receptor–Positive Metastatic Brest Cancer Compared

28 Mar, 2019 | 07:32h | UTC

Overall Survival with Fulvestrant plus Anastrozole in Metastatic Breast Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Gain in Survival with Fulvestrant plus Anastrozole in Metastatic Breast Cancer – MedicalResearch.com (free) AND Fulvestrant plus anastrozole extends lives of women with advanced HR+ breast cancer – SWOG (free)

 


The Measles Virus was Down and Out. Now it’s Primed for a Comeback

28 Mar, 2019 | 07:27h | UTC

The measles virus was down and out. Now it’s primed for a comeback – STAT (free)

 


Review: Imaging in Trauma in Limited-resource Settings

28 Mar, 2019 | 07:29h | UTC

Imaging in trauma in limited-resource settings: A literature review – African Journal of Emergency Medicine (free)

 


Meta-Analysis: Adenosine Deaminase for Diagnosis of Tuberculous Pleural Effusion

28 Mar, 2019 | 07:21h | UTC

Adenosine deaminase for diagnosis of tuberculous pleural effusion: A systematic review and meta-analysis – PLOS One (free)

 


Omega-3 Supplements Do Not Reduce the Risk of Cancer or Cardiovascular Disease

28 Mar, 2019 | 07:24h | UTC

One gram a day of omega-3 supplements does not reduce the risk of cancer or cardiovascular disease – NIHR Signal (free)

Original Article: Randomized Trial: Marine n−3 Fatty Acids and Prevention of Cardiovascular Disease and Cancer (free)

Related Meta-Analysis: Omega-3 Fatty Acid Supplements Don’t Reduce Cardiovascular Risk (free article and commentary)

Related Systematic Review: Omega-3 fatty Acids for the Prevention of Cardiovascular Disease (free review and commentaries)

 


PI-RADS Steering Committee Releases New Version of the Prostate Imaging Reporting and Data System

28 Mar, 2019 | 07:16h | UTC

Prostate Imaging Reporting & Data System – American College of Radiology (free PDF)

News Release: PI-RADS Steering Committee Releases New Version of the Prostate Imaging Reporting and Data System (v2.1 2019) – American College of Radiology (free)

 


Study: Proton Pump Inhibitors and Risk of Acute and Chronic Kidney Disease

28 Mar, 2019 | 07:11h | UTC

Proton Pump Inhibitors and Risk of Acute and Chronic Kidney Disease: A Retrospective Cohort Study – Pharmacotherapy (free)

Commentary: Study: Research ties common heartburn medications to kidney disease and failure – University at Buffalo (free)

Related: Meta-Analysis of Observational Studies: Proton Pump Inhibitors are Associated with Increased Risk of Kidney Disease (link to abstract – $ for full-text) AND Proton Pump Inhibitors: Review of Emerging Concerns (free reviews) AND Deprescribing Proton Pump Inhibitors (free guidelines and reviews)

 


KDOQI US Commentary on the 2017 ACC/AHA Hypertension Guideline

27 Mar, 2019 | 06:22h | UTC

KDOQI US Commentary on the 2017 ACC/AHA Hypertension Guideline – American Journal of Kidney Diseases (free)

 


Wed, March 27 – 10 Stories of The Day!

27 Mar, 2019 | 06:26h | UTC

 

1 – KDOQI US Commentary on the 2017 ACC/AHA Hypertension Guideline – American Journal of Kidney Diseases (free)

 

2 – Clinical guideline for the diagnosis and management of work-related mental health conditions in general practice – National Health and Medical Research Council, Australian Government (NHMRC) (free PDF)

See also: Short Form Guideline (free PDF) AND GP Summary (free PDF)

Commentary: Managing work-related mental health conditions in family medicine – Canadian Medical Association Journal (free for a limited period)

 

3 – Pregnancy-Adapted YEARS Algorithm for Diagnosis of Suspected Pulmonary Embolism – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: YEARS algorithm adaptation for pregnant women helped avoid CT scans for suspected PE – ACP Hospitalist (free) AND Pregnancy-adapted algorithm avoids diagnostic imaging for PE – MedicalXpress (free) AND PE in Pregnancy & YEARS Protocol – Emergency Medicine Literature of Note (free)

 

4 – Antithrombotic Therapy after Acute Coronary Syndrome or PCI in Atrial Fibrillation – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Atrial Fibrillation: Antithrombotic Therapy after Acute Coronary Syndrome or PCI – MedicalResearch.com (free) AND Antithrombotic Regimens Evaluated in Patients With Nonvalvular Atrial Fibrillation After ACS or PCI – MPR (free)

 

5 – Evidence Review: Tranexamic Acid (TXA) for Everything that Bleeds? – REBEL EM (free)

Related: Meta-analysis – Tranexamic acid: is it about time? (free study and commentaries) AND Randomized Controlled Trial: Tranexamic Acid for Hyperacute Primary Intracerebral Hemorrhage (free) AND Systematic Review: Tranexamic Acid for Patients with Epistaxis (free) AND Systematic Review: Antifibrinolytic drugs for treating primary postpartum haemorrhage (free) AND WHO Recommendation on Tranexamic Acid for the Treatment of Postpartum Haemorrhage (free) AND Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (free) AND Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial (landmark trial on the subject)

 

6 – Alex Nowbar’s research reviews, 26 March 2019 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

 

7 – Lipid-lowering agents in older individuals: A systematic Review and Meta-analysis of Randomized Clinical Trials – The Journal of Clinical Endocrinology & Metabolism (free PDF)

 

8 – Evaluation of an Intervention to Reduce Low-Value Preoperative Care for Patients Undergoing Cataract Surgery at a Safety-Net Health System – JAMA Internal Medicine (free for a limited period)

Commentary: Cataract Surgery: QI Initiative Markedly Reduced Low-Value Preoperative Care – MedicalResearch.com (free)

Related: Systematic Review: Routine Preoperative Medical Testing for Cataract Surgery (free)

 

9 – Things We Do For No Reason: Failing to Question a Penicillin Allergy History – Journal of Hospital Medicine (free)

See Complete Series: Things We Do For No Reason (free articles)

 

10 – Night work and miscarriage: a Danish nationwide register-based cohort study – Occupational and Environmental Medicine (free)

Commentaries: Link Between Night Shift Work and Miscarriage – MedicalResearch.com (free) AND Miscarriage risk linked with night shift work – OnMedica (free) AND Night shift work linked to a higher risk of miscarriage – Reuters (free) AND Expert reaction to night shifts and miscarriage – Science Media Centre (free)

 


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