Archives
Review: Obstructive Sleep Apnea and Comorbidities
20 Apr, 2019 | 13:42h | UTCRelated: Obstructive Sleep Apnea in Cardiovascular Disease: A Review of the Literature and Proposed Multidisciplinary Clinical Management Strategy (free reviews)
Ilececum: A Comprehensive Review
20 Apr, 2019 | 13:34h | UTCIlececum: A Comprehensive Review – Canadian Journal of Gastroenterology and Hepatology (free)
Current Concepts in Joint Pain in Knee Osteoarthritis
20 Apr, 2019 | 13:29h | UTCCurrent concepts in joint pain in knee osteoarthritis – Der Schmerz (free)
Guidelines for Endovascular Recanalization Therapy in Patients with Acute Ischemic Stroke
19 Apr, 2019 | 08:40h | UTCRelated: Guideline: Indications for Thrombectomy in Acute Ischemic Stroke from Emergent Large Vessel Occlusion (free guidelines)
Cochrane Review: Nicotine Replacement for Smoking Cessation More Successful in Combination Form
19 Apr, 2019 | 08:42h | UTCDifferent doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation – Cochrane Library (free)
Commentaries: Nicotine replacement: when quitting cigarettes, consider using more nicotine, not less – The Conversation (free) AND Nicotine replacement therapy: new evidence on help to quit smoking – Evidently Cochrane (free) AND Nicotine replacement therapy more successful in combination form – Nuffield Department of Primary Care Health Sciences (free)
Related Commentary on Twitter
Featured Cochrane Review: Different doses, durations and modes of delivery of #nicotine replacement therapy for #smoking cessation from @CochraneTAG – Read comments from lead author https://t.co/WBvMA74iaK and the full review https://t.co/QFLx9Wb9Xc pic.twitter.com/tk2J6WRT3Z
— Cochrane (@cochranecollab) April 18, 2019
Meta-Analysis: Accuracy of Patient Health Questionnaire-9 (PHQ-9) for Screening to Detect Major Depression
19 Apr, 2019 | 08:39h | UTCCommentaries: The accuracy of the Patient Health Questionnaire-9 for detecting major depression – The BMJ Opinion (free) AND Screening tools for depression offer value when combined with an informed shared decision process – The BMJ Opinion (free) AND Using the Patient Health Questionnaire-9 to Screen for Major Depression – NEJM Journal Watch (free)
Fri April 19 – 10 Stories of The Day!
19 Apr, 2019 | 08:45h | UTC
1 – Different doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation – Cochrane Library (free)
Commentaries: Nicotine replacement: when quitting cigarettes, consider using more nicotine, not less – The Conversation (free) AND Nicotine replacement therapy: new evidence on help to quit smoking – Evidently Cochrane (free) AND Nicotine replacement therapy more successful in combination form – Nuffield Department of Primary Care Health Sciences (free)
Related: Guideline: Indications for Thrombectomy in Acute Ischemic Stroke from Emergent Large Vessel Occlusion (free guidelines)
Commentaries: The accuracy of the Patient Health Questionnaire-9 for detecting major depression – The BMJ Opinion (free) AND Screening tools for depression offer value when combined with an informed shared decision process – The BMJ Opinion (free) AND Using the Patient Health Questionnaire-9 to Screen for Major Depression – NEJM Journal Watch (free)
Commentaries: Diabetes drug Metformin may fight heart disease, study says – UPI (free) AND Diabetic drug shown to reduce the risk of heart disease in non-diabetic patients – University of Dundee (free) AND Metformin reduces left ventricular mass in nondiabetic patients with CAD – Cardiovascular Business (free)
5 – Part-revived pig brains raise slew of ethical quandaries – Nature (free)
Original Study: Restoration of brain circulation and cellular functions hours post-mortem – Nature (free)
See also: Pig Experiment Raises Ethical Questions Around Brain Damage – Case Western Reserve University (free) AND Scientists: We kept pig brains alive 10 hours after death. Bioethicists: “Holy shit.” – Vox (free) AND The pigs were dead. But four hours later, scientists restored cellular functions in their brains – STAT (free) AND Scientists Partly Restore Activity in Dead-Pig Brains – The Atlantic (free)
6 – Hypertension in pregnancy: Pathophysiology and treatment – SAGE Open Medicine (free)
Related Guidelines: WHO recommendations: Drug treatment for severe hypertension in pregnancy – World Health Organization (free) AND Hypertension Canada’s 2018 Guidelines for the Management of Hypertension in Pregnancy (free)
Related Meta-Analysis: Drugs for Treating Severe Hypertension in Pregnancy (free study and commentary)
Related Review: State-of-the-Art Diagnosis and Treatment of Hypertension in Pregnancy – Mayo Clinic Proceedings (free)
8 – Management of Hypertension in Chronic Kidney Disease – Drugs (free)
Commentaries: Some patients with imminently fatal cancer still receive treatment – eCancer News (free) AND With Weeks to Live, Many Cancer Patients Try Useless Treatments – HealthDay (free)
Editorial: Perils of Observational Data Analyses (free)
Commentary: Statins for primary prevention: do benefits outweigh DM risk? – Univadis (free registration required)
Related: Cohort Study: Statin Use Associated with a 38% Higher Risk of Incident Type 2 Diabetes (free study and commentaries)
Small Randomized Trial Suggests Metformin May be Effective for Left Ventricular Hypertrophy in Patients with Coronary Artery Disease Without Diabetes
19 Apr, 2019 | 08:37h | UTCCommentaries: Diabetes drug Metformin may fight heart disease, study says – UPI (free) AND Diabetic drug shown to reduce the risk of heart disease in non-diabetic patients – University of Dundee (free) AND Metformin reduces left ventricular mass in nondiabetic patients with CAD – Cardiovascular Business (free)
Part-revived Pig Brains Raise Slew of Ethical Quandaries
19 Apr, 2019 | 08:35h | UTCPart-revived pig brains raise slew of ethical quandaries – Nature (free)
Original Study: Restoration of brain circulation and cellular functions hours post-mortem – Nature (free)
See also: Pig Experiment Raises Ethical Questions Around Brain Damage – Case Western Reserve University (free) AND Scientists: We kept pig brains alive 10 hours after death. Bioethicists: “Holy shit.” – Vox (free) AND The pigs were dead. But four hours later, scientists restored cellular functions in their brains – STAT (free) AND Scientists Partly Restore Activity in Dead-Pig Brains – The Atlantic (free)
Management of Hypertension in Chronic Kidney Disease
19 Apr, 2019 | 08:28h | UTCManagement of Hypertension in Chronic Kidney Disease – Drugs (free)
Hypertension in Pregnancy: Pathophysiology and Treatment
19 Apr, 2019 | 08:33h | UTCHypertension in pregnancy: Pathophysiology and treatment – SAGE Open Medicine (free)
Related Guidelines: WHO recommendations: Drug treatment for severe hypertension in pregnancy – World Health Organization (free) AND Hypertension Canada’s 2018 Guidelines for the Management of Hypertension in Pregnancy (free)
Related Meta-Analysis: Drugs for Treating Severe Hypertension in Pregnancy (free study and commentary)
Related Review: State-of-the-Art Diagnosis and Treatment of Hypertension in Pregnancy – Mayo Clinic Proceedings (free)
Another Observational Study Showing Association of Statin Use with Risk of New‐Onset Diabetes Mellitus
19 Apr, 2019 | 08:25h | UTCEditorial: Perils of Observational Data Analyses (free)
Commentary: Statins for primary prevention: do benefits outweigh DM risk? – Univadis (free registration required)
Related: Cohort Study: Statin Use Associated with a 38% Higher Risk of Incident Type 2 Diabetes (free study and commentaries)
Review: Drug-induced Hypersensitivity Syndrome (DiHS)/Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
19 Apr, 2019 | 08:31h | UTC
Study: Aggressive Treatment Common in Patients with Imminently Fatal de Novo Metastatic Cancer
19 Apr, 2019 | 08:26h | UTCCommentaries: Some patients with imminently fatal cancer still receive treatment – eCancer News (free) AND With Weeks to Live, Many Cancer Patients Try Useless Treatments – HealthDay (free)
Thu April 18 – 10 Stories of The Day!
18 Apr, 2019 | 08:05h | UTC
News Release: WHO releases first guideline on digital health interventions (free)
Related Guidelines: Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline (free) AND Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group (free)
Related Reviews: New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management – Critical Care (free) AND Severe toxicity from checkpoint protein inhibitors: What intensive care physicians need to know? – Annals of Intensive Care (free) AND Checkpoint Inhibitors: The diagnosis and treatment of side effects – Deutsches Ärzteblatt international (free)
5 – Reducing surgical mortality in Scotland by use of the WHO Surgical Safety Checklist – BJS (free)
Commentaries: Hospital deaths after surgery fall after launch of surgical safety checklists in Scotland – Wiley (free) AND Surgical safety checklist linked to decline in hospital deaths – UPI (free)
See also: WHO Surgical Safety Checklist – World Health Organization (free resources)
Commentaries: Expert reaction to screen time and inattention in preschoolers – Science Media Centre (free) AND More Screen Time = More Behavioral Problems in Preschoolers – NEJM Journal Watch (free) AND Increased screen time in preschool is linked to inattention – PLOS (free)
Commentary: Physical Inactivity Not Tied to Dementia – NEJM Journal Watch (free)
Commentaries: Smoking cessation in people with serious mental illness – The Lancet Psychiatry (free) AND New intervention doubles quit rate among smokers with severe mental illness – University of York (free) AND Smoking cessation for people with severe mental illness? “Oh yes they can!” SCIMITAR+ – The Mental Elf (free)
9 – Intensive Care Utilization in Stable Patients With ST-Segment Elevation Myocardial Infarction Treated with Rapid Reperfusion – JACC: Cardiovascular Interventions (link to abstract – $ for full-text)’
Commentaries: Many heart attack patients may be needlessly treated in ICU, study suggests – American College of Cardiology (free) AND Reperfusion Timing May Predict Post-PCI ICU Complication Rate in Stable STEMI – Cardiology Advisor (free) AND Most STEMI Patients Head to ICU After PCI, but Not All Need to Go – TCTMD (free) AND ICUs overused for STEMI patients – Cardiovascular Business (free)
Commentaries: Even moderate red and processed meat eaters at risk of bowel cancer – Cancer Research UK (free) AND Expert reaction to red and processed meat consumption and risk of colorectal cancer – Science Media Centre (free)
ESC Position Paper: Heart Failure in Cardiomyopathies
18 Apr, 2019 | 08:02h | UTC
WHO Guideline: Recommendations on Digital Interventions for Health System Strengthening
18 Apr, 2019 | 08:04h | UTCNews Release: WHO releases first guideline on digital health interventions (free)
NCCN Guideline: Management of Immunotherapy-Related Toxicities
18 Apr, 2019 | 08:00h | UTCRelated Guidelines: Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline (free) AND Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group (free)
Related Reviews: New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management – Critical Care (free) AND Severe toxicity from checkpoint protein inhibitors: What intensive care physicians need to know? – Annals of Intensive Care (free) AND Checkpoint Inhibitors: The diagnosis and treatment of side effects – Deutsches Ärzteblatt international (free)
KDIGO Consensus Statement: Dialysis Initiation, Modality Choice, Access, and Prescription
18 Apr, 2019 | 07:58h | UTC
Cohort Study: Screen-time is Associated with Inattention Problems in Preschoolers
18 Apr, 2019 | 07:53h | UTCCommentaries: Expert reaction to screen time and inattention in preschoolers – Science Media Centre (free) AND More Screen Time = More Behavioral Problems in Preschoolers – NEJM Journal Watch (free) AND Increased screen time in preschool is linked to inattention – PLOS (free)
Reducing Surgical Mortality by Use of the WHO Surgical Safety Checklist
18 Apr, 2019 | 07:56h | UTCReducing surgical mortality in Scotland by use of the WHO Surgical Safety Checklist – BJS (free)
Commentaries: Hospital deaths after surgery fall after launch of surgical safety checklists in Scotland – Wiley (free) AND Surgical safety checklist linked to decline in hospital deaths – UPI (free)
See also: WHO Surgical Safety Checklist – World Health Organization (free resources)
Meta-Analysis: Physical Inactivity, Cardiometabolic Disease, and Risk of Dementia
18 Apr, 2019 | 07:51h | UTCCommentary: Physical Inactivity Not Tied to Dementia – NEJM Journal Watch (free)
Cohort Study: Red and Processed Meat Consumption and Risk of Colorectal Cancer
18 Apr, 2019 | 07:46h | UTCCommentaries: Even moderate red and processed meat eaters at risk of bowel cancer – Cancer Research UK (free) AND Expert reaction to red and processed meat consumption and risk of colorectal cancer – Science Media Centre (free)
Randomized Trial: Smoking Cessation for People with Severe Mental Illness
18 Apr, 2019 | 07:50h | UTCCommentaries: Smoking cessation in people with serious mental illness – The Lancet Psychiatry (free) AND New intervention doubles quit rate among smokers with severe mental illness – University of York (free) AND Smoking cessation for people with severe mental illness? “Oh yes they can!” SCIMITAR+ – The Mental Elf (free)
Observational Study Suggests Many Patients with STEMI Treated with Rapid Reperfusion are Being Needlessly Treated in the ICU
18 Apr, 2019 | 07:48h | UTCIntensive Care Utilization in Stable Patients With ST-Segment Elevation Myocardial Infarction Treated with Rapid Reperfusion – JACC: Cardiovascular Interventions (link to abstract – $ for full-text)’
Commentaries: Many heart attack patients may be needlessly treated in ICU, study suggests – American College of Cardiology (free) AND Reperfusion Timing May Predict Post-PCI ICU Complication Rate in Stable STEMI – Cardiology Advisor (free) AND Most STEMI Patients Head to ICU After PCI, but Not All Need to Go – TCTMD (free) AND ICUs overused for STEMI patients – Cardiovascular Business (free)
Related Commentary on Twitter
Cardiac ICUs – make space for those who actually need it!
Analysis of STEMI patients treated at ICUs (>80%!), <20% actually needed ICU support (still surprisingly high number?)
whats your procedure?#CICU #CCU #Cardiology #Cardiotwitter https://t.co/252FzN2rmH pic.twitter.com/lhCIm75qo5
— Konstantin Krychtiuk (@krychtiukmd) April 15, 2019