Archives
A Decade of Progress in Critical Care Echocardiography
1 May, 2019 | 07:16h | UTCA decade of progress in critical care echocardiography: a narrative review – Intensive Care Medicine (free)
Related Commentary on Twitter
Should all ICU physicians know basic CCE?
Narrative review by @AVBmir @Echotrainer et al on the progress of critical care echocardiograhy (CCE) during the last decade.
Available at https://t.co/K9N4yGXT3M@ClinMedJournals @Dr_Cit @ESICM @pbhjortrup pic.twitter.com/vSWe8Ml5hl— Intensive Care Medicine (@yourICM) April 25, 2019
Diagnostic and Therapeutic Approach to Infectious Diseases in Solid Organ Transplant Recipients
1 May, 2019 | 07:22h | UTCRelated: 10 Tips for Intensive Care Management of Transplanted Patients (free articles) AND Special Issue: Infections in Solid Organ Transplantation Guidelines (free articles)
Source: Critical Care Reviews Newsletter
Wed May 1 – 10 Stories of The Day!
1 May, 2019 | 10:01h | UTC
Related: 10 Tips for Intensive Care Management of Transplanted Patients (free articles) AND Special Issue: Infections in Solid Organ Transplantation Guidelines (free articles)
Source: Critical Care Reviews Newsletter
Commentary: Shorter Treatment Succeeds in Septic Arthritis – RheumNow (free)
4 – Risk‐reducing medications for primary breast cancer: a network meta‐analysis – Cochrane Library (free)
Summary: Medicines to prevent breast cancer in women at above-average risk of developing breast cancer – Cochrane Library (free)
5 – Opinion: How to Make Doctors Think About Death – The New York Times (10 articles per month are free)
“End-of-life treatment guidelines would help families, physicians and nurses confront the inevitable with care and compassion.”
6 – Is It Time for Safeguards in the Adoption of Robotic Surgery? – JAMA (free for a limited period)
Related: FDA Cautions Patients, Providers About Using Robotically-assisted Surgical Devices for Mastectomy and Other Cancer-related Surgeries (free safety alert and commentary)
“To date, most studies demonstrating potential benefits of robotic-assisted surgery have been small, single-centered reports without rigorous controls.”
7 – Clinical Update: Active Surveillance of Low-Risk Thyroid Cancer – JAMA (free for a limited period)
“Individuals should also be aware that there are currently no head-to-head randomized trials that compared active surveillance of low-risk thyroid cancer with thyroid surgery, and that there remain uncertainties related to the risks and benefits of each approach.”
8 – Alex Nowbar’s research reviews, 30 April 2019 – The BMJ Opinion (free)
9 – Perioperative Fluid Therapy for Major Surgery – Anesthesiology (free)
Source: Critical Care Reviews Newsletter
10 – Effect of Initial Management With Aflibercept vs Laser Photocoagulation vs Observation on Vision Loss Among Patients With Diabetic Macular Edema Involving the Center of the Macula and Good Visual Acuity: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Patients With Good Vision and Diabetic Macular Edema Involving the Center of the Macula: To Treat or Not to Treat? (free)
Commentary: Watchful waiting reasonable for patients with diabetic macular edema and good vision – NIH News Releases (free)
See also: Visual Abstract
Randomized Trial: Two Weeks vs. Four Weeks of Antibiotic Therapy for Native Joint Bacterial Arthritis
1 May, 2019 | 07:12h | UTCCommentary: Shorter Treatment Succeeds in Septic Arthritis – RheumNow (free)
Meta-Analysis: Risk‐reducing Medications for Primary Breast Cancer
1 May, 2019 | 07:10h | UTCRisk‐reducing medications for primary breast cancer: a network meta‐analysis – Cochrane Library (free)
Summary: Medicines to prevent breast cancer in women at above-average risk of developing breast cancer – Cochrane Library (free)
Related Commentary on Twitter
New @CochraneBCancer Review – Risk-reducing medications for primary breast cancer https://t.co/NOidQ4HrhV 6 studies enrolling 50,927 women. Specialized method, network meta‐analysis, allowed comparison of medications never directly compared to each other in a study.
— The Cochrane Library (@CochraneLibrary) April 30, 2019
Opinion: How to Make Doctors Think About Death
1 May, 2019 | 07:07h | UTCOpinion: How to Make Doctors Think About Death – The New York Times (10 articles per month are free)
“End-of-life treatment guidelines would help families, physicians and nurses confront the inevitable with care and compassion.”
Opinion: Is It Time for Safeguards in the Adoption of Robotic Surgery?
1 May, 2019 | 07:05h | UTCIs It Time for Safeguards in the Adoption of Robotic Surgery? – JAMA (free for a limited period)
Related: FDA Cautions Patients, Providers About Using Robotically-assisted Surgical Devices for Mastectomy and Other Cancer-related Surgeries (free safety alert and commentary)
“To date, most studies demonstrating potential benefits of robotic-assisted surgery have been small, single-centered reports without rigorous controls.”
Alex Nowbar’s research reviews – 30 April 2019
1 May, 2019 | 07:02h | UTCAlex Nowbar’s research reviews, 30 April 2019 – The BMJ Opinion (free)
Perioperative Fluid Therapy for Major Surgery
1 May, 2019 | 07:00h | UTCPerioperative Fluid Therapy for Major Surgery – Anesthesiology (free)
Source: Critical Care Reviews Newsletter
Clinical Update: Active Surveillance of Low-Risk Thyroid Cancer
1 May, 2019 | 07:04h | UTCActive Surveillance of Low-Risk Thyroid Cancer – JAMA (free for a limited period)
“Individuals should also be aware that there are currently no head-to-head randomized trials that compared active surveillance of low-risk thyroid cancer with thyroid surgery, and that there remain uncertainties related to the risks and benefits of each approach.”
Randomized Trial Evaluates Watchful Waiting for Patients with Diabetic Macular Edema and Good Vision
1 May, 2019 | 06:58h | UTCEffect of Initial Management With Aflibercept vs Laser Photocoagulation vs Observation on Vision Loss Among Patients With Diabetic Macular Edema Involving the Center of the Macula and Good Visual Acuity: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Patients With Good Vision and Diabetic Macular Edema Involving the Center of the Macula: To Treat or Not to Treat? (free)
Commentary: Watchful waiting reasonable for patients with diabetic macular edema and good vision – NIH News Releases (free)
See also: Visual Abstract
Tue April 30 – 10 Stories of The Day!
30 Apr, 2019 | 02:51h | UTC
1 – Report: No Time to Wait: Securing the future from drug-resistant infections – World Health Organization (free PDF)
News Release: New report calls for urgent action to avert antimicrobial resistance crisis – World Health Organization (free)
Commentary: UN report calls for urgent action against antimicrobial resistance – CIDRAP (free)
3 – Heart failure in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference – Kidney International (free) (via @paomorejon)
Commentaries: Childhood mortality declining globally but disability on the rise – Reuters (free) AND Child and adolescent deaths decreased by half worldwide since 1990 Journalist’s Resource (free)
5 – Association Between Peripheral Neuropathy and Exposure to Oral Fluoroquinolone or Amoxicillin-Clavulanate Therapy – JAMA Neurology (free for a limited period)
Editorial: On the Association Between Fluoroquinolones and Neuropathy (free)
Related: Committee Recommends New Restrictions on the use of Fluoroquinolones (free report and commentaries)
6 – Restrictive strategy versus usual care for cholecystectomy in patients with gallstones and abdominal pain (SECURE): a multicentre, randomised, parallel-arm, non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Commentary: Applying Strict Criteria for Gallbladder Removal Doesn’t Improve Pain – NEJM Journal Watch (free)
Source: EvidenceAlerts
“Our findings suggest that to provide clinical benefit with the least effect on growth, the number of repeat treatment courses should be limited to a maximum of three and the total dose to between 24 mg and 48 mg.”
Commentary: NNT with statins is 400 for lower risk eligible patients, researchers estimate – Pulse (free)
9 – Effect of Gastric Residual Evaluation on Enteral Intake in Extremely Preterm Infants: A Randomized Clinical Trial – JAMA Pediatrics (free for a limited period)
10 – Release of “13 Reasons Why” associated with increase in youth suicide rates – NIH News Releases (free)
Original Study: Association Between the Release of Netflix’s 13 Reasons Why and Suicide Rates in the United States: An Interrupted Times Series Analysis – Journal of the American Academy of Child and Adolescent Psychiatry (link to abstract – $ for full-text)
Related Study: Internet Searches for Suicide Following the Release of “13 Reasons Why” (free study and commentaries)
“NIH-supported study highlights the importance of responsible portrayal of suicide by the media.”
Guideline: Unscheduled Procedural Sedation
30 Apr, 2019 | 02:47h | UTC
WHO Report: Urgent Action Needed to Avert Antimicrobial Resistance Crisis
30 Apr, 2019 | 02:49h | UTCReport: No Time to Wait: Securing the future from drug-resistant infections – World Health Organization (free PDF)
News Release: New report calls for urgent action to avert antimicrobial resistance crisis – World Health Organization (free)
Commentary: UN report calls for urgent action against antimicrobial resistance – CIDRAP (free)
KDIGO Controversies Conference: Heart Failure in Chronic Kidney Disease
30 Apr, 2019 | 02:44h | UTCHeart failure in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference – Kidney International (free) (via @paomorejon)
Study: Fluoroquinolones Associated with Peripheral Neuropathy
30 Apr, 2019 | 02:40h | UTCAssociation Between Peripheral Neuropathy and Exposure to Oral Fluoroquinolone or Amoxicillin-Clavulanate Therapy – JAMA Neurology (free for a limited period)
Editorial: On the Association Between Fluoroquinolones and Neuropathy (free)
Related: Committee Recommends New Restrictions on the use of Fluoroquinolones (free report and commentaries)
Randomized Trial: Restrictive Strategy vs. Usual Care for Cholecystectomy in Patients with Gallstones and Abdominal Pain
30 Apr, 2019 | 02:38h | UTCRestrictive strategy versus usual care for cholecystectomy in patients with gallstones and abdominal pain (SECURE): a multicentre, randomised, parallel-arm, non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Commentary: Applying Strict Criteria for Gallbladder Removal Doesn’t Improve Pain – NEJM Journal Watch (free)
Related Commentary on Twitter
NEW Research—Restrictive strategy versus usual care for cholecystectomy in patients with #gallstones and #abdominalpain (SECURE): a multicentre, randomised, parallel-arm, non-inferiority trial https://t.co/kRMnZScaM9 pic.twitter.com/pdrzLLnZs8
— The Lancet (@TheLancet) April 29, 2019
Global Burden of Diseases Study: Diseases, Injuries, and Risk Factors in Child and Adolescent Health
30 Apr, 2019 | 02:42h | UTCCommentaries: Childhood mortality declining globally but disability on the rise – Reuters (free) AND Child and adolescent deaths decreased by half worldwide since 1990 – Journalist’s Resource (free)
Relate Commentary on Twitter
Our latest study, "Diseases, Injuries, and Risk Factors in Child and Adolescent Health, 1990 to 2017," was just published in @JAMAPediatrics. Read the full study online: https://t.co/3K0l08WzpF pic.twitter.com/TIRksZBiD6
— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) April 29, 2019
Meta-Analysis: Effects of Repeat Prenatal Corticosteroids Given to Women at Risk of Preterm Birth
30 Apr, 2019 | 02:37h | UTCSource: EvidenceAlerts
“Our findings suggest that to provide clinical benefit with the least effect on growth, the number of repeat treatment courses should be limited to a maximum of three and the total dose to between 24 mg and 48 mg.”
Study: Benefits of Statins Questioned for Primary Prevention of Cardiovascular Disease
30 Apr, 2019 | 02:35h | UTCCommentary: NNT with statins is 400 for lower risk eligible patients, researchers estimate – Pulse (free)
Randomized Trial: Omission of Gastric Residual Evaluation Seems to Be Safe and Increases Enteral Intake in Extremely Preterm Infants
30 Apr, 2019 | 02:34h | UTCEffect of Gastric Residual Evaluation on Enteral Intake in Extremely Preterm Infants: A Randomized Clinical Trial – JAMA Pediatrics (free for a limited period)
Release of “13 Reasons Why” Associated with Increase in Youth Suicide Rates
30 Apr, 2019 | 02:32h | UTCRelease of “13 Reasons Why” associated with increase in youth suicide rates – NIH News Releases (free)
Original Study: Association Between the Release of Netflix’s 13 Reasons Why and Suicide Rates in the United States: An Interrupted Times Series Analysis – Journal of the American Academy of Child and Adolescent Psychiatry (link to abstract – $ for full-text)
Related Study: Internet Searches for Suicide Following the Release of “13 Reasons Why” (free study and commentaries)
“NIH-supported study highlights the importance of responsible portrayal of suicide by the media.”
Strategies for Optimal Calorie Administration in Critically Ill Patients
30 Apr, 2019 | 02:22h | UTCStrategies for optimal calorie administration in critically ill patients – Journal of Intensive Care (free)
Related Guidelines: ASPEN/SCCM Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Adult Critically Ill Patient (free) AND ESPEN guideline on clinical nutrition in the intensive care unit – Clinical Nutrition (free)
Cochrane Review: Interventions for Hand Eczema
30 Apr, 2019 | 02:21h | UTCInterventions for hand eczema – Cochrane Library (free)
Summary: Treatments for hand eczema – Cochrane Library (free)
Randomized Trial: When Is It Best to Start the Parkinson’s Drug, Levodopa?
30 Apr, 2019 | 02:18h | UTCWhen is it best to start the Parkinson’s drug, levodopa? – NIHR Signal (free)
Original Study: Randomized Delayed-Start Trial of Levodopa in Parkinson’s Disease (link to abstract and commentary)


