Archives
Acute Flaccid Myelitis: Something Old and Something New
21 May, 2019 | 18:42h | UTCAcute Flaccid Myelitis: Something Old and Something New – mBio (free)
Related: Acute Flaccid Myelitis: A Clinical Overview for 2019 – Mayo Clinic Proceedings (free) AND CDC Investigates Acute Flaccid Myelitis Cases (free study and commentaries)
Review: Neuroimaging in Lewy Body Dementia
21 May, 2019 | 18:34h | UTCNeuroimaging in Lewy body dementia – Journal of Neurology (free)
A Review of Novel Antidepressants: A Guide for Clinicians
21 May, 2019 | 14:56h | UTCA Review of Novel Antidepressants: A Guide for Clinicians – Cureus (free)
Consensus Statement: Treatment of Paroxysmal Nocturnal Hemoglobinuria
21 May, 2019 | 14:54h | UTC
ASA Policy Statement: Recommendations for the Establishment of Stroke Systems of Care
21 May, 2019 | 13:43h | UTCNews Release: New recommendations for stroke systems of care to improve patient outcomes (free)
Meta-Analysis: Laparoscopic vs. Open Liver Resection for Hepatocellular Carcinoma
21 May, 2019 | 13:28h | UTC
Tue May 21 – 10 Stories of The Day!
21 May, 2019 | 06:23h | UTC
#ATS2019 – Highlights from the 2019 Meeting of the American Thoracic Society
1 – Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis – JAMA (free for a limited period)
Editorial: New Phenotypes for Sepsis: The Promise and Problem of Applying Machine Learning and Artificial Intelligence in Clinical Research (free for a limited period)
Commentary: Big data reveals hidden subtypes of sepsis – University of Pittsburgh (free)
Just Presented at the 2019 Meeting of the American Thoracic Society.
2 – Early Sedation with Dexmedetomidine in Critically Ill Patients – New England Journal of Medicine (link to abstract – $ for full-text)
Just Presented at the 2019 Meeting of the American Thoracic Society.
3 – Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Sedation and controlled paralysis do not improve survival of ICU patients with ARDS – University of Pittsburgh (free)
Just Presented at the 2019 Meeting of the American Thoracic Society.
4 – Controlled Trial of Budesonide–Formoterol as Needed for Mild Asthma – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Treatment Changes for Mild Asthma? – NEJM Journal Watch (free)
Just Presented at the 2019 Meeting of the American Thoracic Society.
5 – Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Large portion of patients with mild persistent asthma and low sputum eosinophils respond equally well to inhaled corticosteroids as placebo – NIH News Releases (free)
Just Presented at the 2019 Meeting of the American Thoracic Society.
6 – Nintedanib for Systemic Sclerosis–Associated Interstitial Lung Disease – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Nintedanib slows lung function decline in SSc-associated interstitial lung disease – Medicine Matters (free)
Just Presented at the 2019 Meeting of the American Thoracic Society.
7 – Google’s AI improves accuracy of lung cancer diagnosis, study shows – STAT (free)
See also: A.I. Took a Test to Detect Lung Cancer. It Got an A. – The New York Times (10 articles per month are free)
Original Article: End-to-end lung cancer screening with three-dimensional deep learning on low-dose chest computed tomography – Nature Medicine (link to abstract – $ for full-text)
8 – Viewpoint: Millions Take Gabapentin for Pain. But There’s Scant Evidence It Works. – The New York Times (10 articles per month are free)
Related: Meta-Analysis: Anticonvulsants in the Treatment of Low Back Pain and Lumbar Radicular Pain (free) AND Benefits and safety of gabapentinoids in chronic low back pain (free) AND Less is More: A Clinical Overview of Off-label Use of Gabapentinoid Drugs (link to abstract)
9 – Viewpoint: Artificial Intelligence in Health Care: Will the Value Match the Hype? – JAMA (free for a limited period)
10 – SCAI clinical expert consensus statement on the classification of cardiogenic shock – Catheterization Cardiovascular Interventions (free) (via @paomorejon)
Commentaries: SCAI releases multi-society endorsed consensus on the classification stages of cardiogenic shock – Society for Cardiovascular Angiography and Interventions (free) AND SCAI Clinical Expert Consensus Statement on Cardiogenic Shock – American College of Cardiology (free)
“Endorsed by the American College of Cardiology (ACC), the American Heart Association (AHA), the Society of Critical Care Medicine (SCCM), and the Society of Thoracic Surgeons (STS) in April 2019”
#ATS2019 – Controlled Trial of Budesonide–Formoterol as Needed for Mild Asthma
21 May, 2019 | 06:16h | UTCControlled Trial of Budesonide–Formoterol as Needed for Mild Asthma – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Treatment Changes for Mild Asthma? – NEJM Journal Watch (free)
Just Presented at the 2019 Meeting of the American Thoracic Society.
#ATS2019 – Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis
21 May, 2019 | 06:21h | UTCDerivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis – JAMA (free for a limited period)
Editorial: New Phenotypes for Sepsis: The Promise and Problem of Applying Machine Learning and Artificial Intelligence in Clinical Research (free for a limited period)
Commentary: Big data reveals hidden subtypes of sepsis – University of Pittsburgh (free)
Just Presented at the 2019 Meeting of the American Thoracic Society.
#ATS2019 – Randomized Trial: Nintedanib for Systemic Sclerosis–Associated Interstitial Lung Disease
21 May, 2019 | 06:13h | UTCNintedanib for Systemic Sclerosis–Associated Interstitial Lung Disease – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Nintedanib slows lung function decline in SSc-associated interstitial lung disease – Medicine Matters (free)
Just Presented at the 2019 Meeting of the American Thoracic Society.
#ATS2019 – [Abstract Only] Randomized Trial: Early Sedation with Dexmedetomidine Not Helpful in Critically Ill Patients
21 May, 2019 | 06:19h | UTCEarly Sedation with Dexmedetomidine in Critically Ill Patients – New England Journal of Medicine (link to abstract – $ for full-text)
Just Presented at the 2019 Meeting of the American Thoracic Society.
#ATS2019 – Randomized Trial: Early Neuromuscular Blockade Do Not Benefit Patients with Acute Respiratory Distress Syndrome
21 May, 2019 | 06:18h | UTCEarly Neuromuscular Blockade in the Acute Respiratory Distress Syndrome – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Sedation and controlled paralysis do not improve survival of ICU patients with ARDS – University of Pittsburgh (free)
Just Presented at the 2019 Meeting of the American Thoracic Society.
Related Commentary on Twitter
This trial revisited research conducted about a decade ago that showed a survival benefit with early neuromuscular blockade in patients with acute respiratory distress syndrome (ARDS). See the results of the new trial: https://t.co/lcLOUirsOM #ATS2019
— NEJM (@NEJM) May 19, 2019
#ATS2019 – Randomized Trial: Patients with Mild Asma and Low Sputum Eosinophil Levels Do Not Benefit from Inhaled Corticosteroids
21 May, 2019 | 06:15h | UTCMometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Large portion of patients with mild persistent asthma and low sputum eosinophils respond equally well to inhaled corticosteroids as placebo – NIH News Releases (free)
Just Presented at the 2019 Meeting of the American Thoracic Society.
Google’s AI Improves Accuracy of Lung Cancer Diagnosis, Study Shows
21 May, 2019 | 06:10h | UTCGoogle’s AI improves accuracy of lung cancer diagnosis, study shows – STAT (free)
See also: A.I. Took a Test to Detect Lung Cancer. It Got an A. – The New York Times (10 articles per month are free)
Original Article: End-to-end lung cancer screening with three-dimensional deep learning on low-dose chest computed tomography – Nature Medicine (link to abstract – $ for full-text)
Viewpoint – “Millions Take Gabapentin for Pain. But There’s Scant Evidence It Works.”
21 May, 2019 | 06:04h | UTCMillions Take Gabapentin for Pain. But There’s Scant Evidence It Works. – The New York Times (10 articles per month are free)
Related: Meta-Analysis: Anticonvulsants in the Treatment of Low Back Pain and Lumbar Radicular Pain (free) AND Benefits and safety of gabapentinoids in chronic low back pain (free) AND Less is More: A Clinical Overview of Off-label Use of Gabapentinoid Drugs (link to abstract)
SCAI Clinical Expert Consensus Statement on the Classification of Cardiogenic Shock
21 May, 2019 | 05:59h | UTCSCAI clinical expert consensus statement on the classification of cardiogenic shock – Catheterization Cardiovascular Interventions (free) (via @paomorejon)
Related: Cardiogenic shock: evolving definitions and future directions in management – openheart (free)
Commentaries: SCAI releases multi-society endorsed consensus on the classification stages of cardiogenic shock – Society for Cardiovascular Angiography and Interventions (free) AND SCAI Clinical Expert Consensus Statement on Cardiogenic Shock – American College of Cardiology (free)
“Endorsed by the American College of Cardiology (ACC), the American Heart Association (AHA), the Society of Critical Care Medicine (SCCM), and the Society of Thoracic Surgeons (STS) in April 2019”
Observational Study Suggests Opioids, SSRIs and Steroids May Increase Fracture Risk in Patients with Rheumatoid Arthritis
20 May, 2019 | 22:42h | UTCMedications associated with fracture risk in patients with rheumatoid arthritis – Annals of Rheumatic Diseases (link to abstract – $ for full-text)
Commentary: Opioids, SSRIs and Steroids Increase Fracture Risk in RA – RheumNow (free)
Viewpoint – “Artificial Intelligence in Health Care: Will the Value Match the Hype?”
21 May, 2019 | 06:02h | UTCArtificial Intelligence in Health Care: Will the Value Match the Hype? – JAMA (free for a limited period)
Final Overall Survival Analysis of the LATITUDE Trial in Newly Diagnosed, High-Risk, Metastatic, Castration-Sensitive Prostate Cancer
20 May, 2019 | 22:47h | UTCOriginal Article: Abiraterone acetate plus prednisone in patients with newly diagnosed high-risk metastatic castration-sensitive prostate cancer (LATITUDE): final overall survival analysis of a randomised, double-blind, phase 3 trial – The Lancet Oncology (link to abstract – 4 for full-text)
Blood Pressure and the New ACC/AHA Hypertension Guidelines
20 May, 2019 | 17:09h | UTCBlood Pressure and the New ACC/AHA Hypertension Guidelines – Trends in Cardiovascular Medicine (free)
Original Guideline: 2017 Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines (free)
Related: 2018 ESC/ESH Guidelines for the management of arterial hypertension – European Heart Journal (free) AND What’s New in the ESC 2018 Guidelines for Arterial hypertension: The Ten Most Important Messages (free) AND AAFP Decides to Not Endorse AHA/ACC Hypertension Guideline – American Academy of Family Physicians (free) AND Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Synopsis of the 2017 American College of Cardiology/American Heart Association Hypertension Guideline – Annals of Internal Medicine (free) AND Hypertension Canada’s 2018 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults and Children – Canadian Journal of Cardiology (free)
[Abstract Only] Meta-Analysis: Vitamin C Does Not Improve Outcomes in Critically Ill Patients
20 May, 2019 | 22:26h | UTCThe Effect of Vitamin C on Clinical Outcome in Critically Ill Patients: A Systematic Review With Meta-Analysis of Randomized Controlled Trials – Critical Care Medicine (link to abstract – $ for full-text)
Podcast: Best Practices Update and the Future of Heart Failure with Preserved EF
20 May, 2019 | 22:22h | UTCBest practices update and the future of heart failure with preserved EF – The Curbsiders Internal Medicine Podcast (free audio and summary)
Review: Pediatric Hand and Wrist Fractures
20 May, 2019 | 15:23h | UTCPediatric Hand and Wrist Fractures – Clinics in Plastic Surgery (free)
Review: Hand Infections
20 May, 2019 | 15:24h | UTCHand Infections – Clinics in Plastic Surgery (free)
Review: Managing Mutilating Hand Injuries
20 May, 2019 | 15:21h | UTCManaging Mutilating Hand Injuries – Clinics in Plastic Surgery (free)