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Deprescribing in Older Adults With Cardiovascular Disease

– its hard, it takes time, but it is probably as important as prescribing!#Cardiology #Cardiotwitter #publichealth https://t.co/1urlIi61RD pic.twitter.com/hOXUlZ5M7u

— Konstantin Krychtiuk (@krychtiukmd) May 25, 2019

Study: Preventable Cancer Burden Associated with Poor Diet

28 May, 2019 | 00:47h | UTC

Preventable Cancer Burden Associated with Poor Diet in the United States – JNCI Cancer Spectrum (free PDF)

Commentaries: New study estimates preventable cancer burden linked to poor diet in the US – Tufts University (free) AND Poor diet may increase risk for preventable cancers – UPI (free)

[Abstract Only] Randomized Trial: Gentamicin vs. Ceftriaxone for the Treatment of Gonorrhea

28 May, 2019 | 00:51h | UTC

Gentamicin compared with ceftriaxone for the treatment of gonorrhoea (G-ToG): a randomised non-inferiority trial – The Lancet (link to abstract – $ for full-text)

Commentaries: Clinical trial finds gentamicin inferior to ceftriaxone for gonorrhea – CIDRAP (free) AND Drug combination could be effective for treatment resistant gonorrhea – NIHR (free) AND New drug combination could be effective for treatment-resistant gonorrhea – OnMedica (free) AND Quick Take: Gentamicin compared with ceftriaxone for the treatment of gonorrhoea (G-ToG) – 2 Minute Medicine (free)

Guideline: Change in Renal Function Associated with Drug Treatment in Heart Failure

26 May, 2019 | 20:16h | UTC

Change in renal function associated with drug treatment in heart failure: national guidance – Heart (free)

Mon May 27 – 10 Stories of The Day!

27 May, 2019 | 00:01h | UTC

1 – Deprescribing in Older Adults with Cardiovascular Disease – Journal of the American College of Cardiology (free for a limited period)

Related: Position Statement: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject)

2 – Change in renal function associated with drug treatment in heart failure: national guidance – Heart (free)

3 – Solutions for non-communicable disease prevention and control – The BMJ / World Health Organization (free articles)

Editorial: Mobilising society to implement solutions for non-communicable diseases

– National action plans to tackle NCDs: role of stakeholder network analysis

– Asking the right question: implementation research to accelerate national non-communicable disease responses

– Using economic evidence to support policy decisions to fund interventions for non-communicable diseases

– Medical education must change if we are to tackle the causes of non-communicable diseases

– Tackling NCDs in humanitarian settings is a growing challenge

– Better health and wellbeing for billion more people: integrating non-communicable diseases in primary care

– Social determinants and non-communicable diseases: time for integrated action

– Integrating mental health with other non-communicable diseases

– Environmental risks and non-communicable diseases

– A life-course approach to the prevention and control of noncommunicable diseases

– Transforming the food system to fight non-communicable diseases

4 – Daily Self‐Weighing to Prevent Holiday‐Associated Weight Gain in Adults – Obesity (free)

Commentaries: Daily self-weighing can prevent holiday weight gain – University of Georgia (free) AND Researchers reveal new strategy for preventing holiday weight gain – The Obesity Society (free) AND Weighing yourself every day could prevent weight gain – Medical News Today (free)

5 – Long term tapering versus standard prednisolone treatment for first episode of childhood nephrotic syndrome: phase III randomised controlled trial and economic evaluation – The BMJ (free)

6 – Evolving Issues in the Treatment of Depression – JAMA (free for a limited period)

Author Interview: New Approaches to Management of Depression (free audio)

7 – Trends in Incidence and Stage at Diagnosis of Colorectal Cancer in Adults Aged 40 Through 49 Years, 1975-2015 – JAMA (free for a limited period)

Commentaries: CRC rates appear to be rising among younger adults in U.S., Europe – ACP Gastroenterology (free) AND More Younger People Getting Later Stage Colon Cancer – MedicalResearch.com (free)

Related: Two Studies Point to Increase in Colorectal Cancer Incidence in Young Adults (link to abstracts and commentaries)

8 – At $2.1 Million, New Gene Therapy Is The Most Expensive Drug Ever – NPR (free)

“The price set by the Swiss drugmaker Novartis may be the world’s highest for a single treatment — prompting renewed debate about how society will pay for gene-therapy breakthroughs.” (from the New York Times)

9 – Current Concepts in the Management of the Difficult Pediatric Airway – Current Anesthesiology Reports (free)

10 – Risks and clinical predictors of cirrhosis and hepatocellular carcinoma diagnoses in adults with diagnosed NAFLD: real-world study of 18 million patients in four European cohorts – BMC Medicine (free)

Commentaries: Diabetes patients at higher risk of deadly liver disease, finds study of 18 million people – Queen Mary University of London (free) AND Diabetes patients at high risk of serious NAFLD outcomes – Medwire News (free) AND Cirrhosis and liver cancer risk higher in people with type 2 diabetes – Medical News Today (free)