Archives

Clinical Guide and Update on Porphyrias

26 Jul, 2019 | 01:11h | UTC

Clinical Guide and Update on Porphyrias – Gastroenterology (free)

Viewpoint: Realizing Shared Decision-making in Practice

26 Jul, 2019 | 01:01h | UTC

Realizing Shared Decision-making in Practice – JAMA (free for a limited period)

Related Viewpoint: Shared Decision Making and the Importance of Time – JAMA (free)

Meta-Analysis: Risk of Recurrent Thromboembolism after Discontinuation of Anticoagulant Treatment for First Unprovoked Venous Thromboembolism Event

26 Jul, 2019 | 01:06h | UTC

Long term risk of symptomatic recurrent venous thromboembolism after discontinuation of anticoagulant treatment for first unprovoked venous thromboembolism event: systematic review and meta-analysis – The BMJ (free)

Commentary: Long-Term Risk for Recurrent VTE Significant After Stopping Anticoagulation – NEJM Journal Watch (free)

“the risk of recurrent VTE was 10% in the first year after treatment, 16% at two years, 25% at five years, and 36% at 10 years, with 4% of recurrent VTE events resulting in death.”

Related Commentary on Twitter

Excited to share my first study published today in @bmj_latest on recurrence risk after stopping #anticoagulation for unprovoked #VTE. Big thanks to the MARVELOUS collaborators, @CIHR_IRSC for funding/support & @RodgerMarc for continued mentorship https://t.co/jnT86dRzHK #phdlife pic.twitter.com/SSVTYwkXth

— Faizan Khan, PhD (@FaizanK91) July 25, 2019

Viewpoint: Harms from Uninformative Clinical Trials

26 Jul, 2019 | 01:04h | UTC

Harms from Uninformative Clinical Trials – JAMA (free)

“An uninformative trial is one that provides results that are not of meaningful use for a patient, clinician, researcher, or policy maker.”

Meta-Analysis: Impact of Furosemide on Mortality and the Requirement for Renal Replacement Therapy in Acute Kidney Injury

26 Jul, 2019 | 00:45h | UTC

Impact of furosemide on mortality and the requirement for renal replacement therapy in acute kidney injury: a systematic review and meta-analysis of randomised trials – Annals of Intensive Care (free)

Randomized Trial: Proton Pump Inhibitor Not Effective for Prevention of Gastroduodenal Events in Patients Receiving Low-dose Anticoagulation and/or Aspirin

26 Jul, 2019 | 00:44h | UTC

Pantoprazole to Prevent Gastroduodenal Events in Patients Receiving Rivaroxaban and/or Aspirin in a Randomized, Double-Blind, Placebo-Controlled Trial – Gastroenterology (free)

[Abstract Only] Meta-Analysis: Catheter Ablation Improves Outcomes in Patients with Atrial Fibrillation Complicated with Heart Failure

26 Jul, 2019 | 00:29h | UTC

Rhythm control for patients with atrial fibrillation complicated with heart failure in the contemporary era of catheter ablation: a stratified pooled analysis of randomized data – European Heart Journal (link to abstract – $ for full-text)

Commentary: Rhythm Control for Atrial Fibrillation With Heart Failure – American College of Cardiology (free)

Systematic Review: Interventions for Preventing Obesity in Children

26 Jul, 2019 | 00:32h | UTC

Interventions for preventing obesity in children – Cochrane Library (free)

Summary: Do diet and physical activity strategies help prevent obesity in children (aged 0 to 18 years)? – Cochrane Library (free)

Thu July 25 – 10 Stories of The Day!

25 Jul, 2019 | 02:20h | UTC

1 – Preventing dementia by preventing stroke: The Berlin Manifesto – Alzheimer’s & Dementia (free)

Commentaries: Group calls on international community to prevent dementia by preventing stroke – University of Western Ontario (free) AND Stroke Prevention Best Path to Dementia Reduction, Experts Say – Medscape (free registration required)

2 – Association Between Stress Testing–Induced Myocardial Ischemia and Clinical Events in Patients With Multivessel Coronary Artery Disease – JAMA Internal Medicine (free)

Commentary: Baseline Ischemia Not Linked to 10-Year Events in Stable CAD: MASS II Analysis – TCTMD (free) AND Stress Testing–Induced Myocardial Ischemia and Clinical Events in Multivessel CAD – Latest in Cardiology (free)

3 – How a data detective exposed suspicious medical trials – Nature (free)

Related: Dozens of recent clinical trials may contain wrong or falsified data (free study by John Carlisle)

“Anaesthetist John Carlisle has spotted problems in hundreds of research papers — and spurred a leading medical journal to change its practice.”

4 – Allergan Recalls Textured Breast Implant Tied to Rare Cancer – Associated Press (free)

Related: FDA Report: 660 Cases of Breast Implant-Associated Anaplastic Large Cell Lymphoma (link to statement and other studies)

5 – Is one dose of human papillomavirus vaccine as effective as three?: A national cohort analysis – Papillomavirus Research (free)

Commentary: One dose of HPV vaccine may be enough, Australian research finds – University of Melbourne (free)

6 – Renal Replacement Therapy in the Critical Care Setting – Critical Care Research and Practice (free)

Related Meta-Analysis: Early Initiation of Renal Replacement Therapy in Critically Ill Patients (free)

Related Randomized Trial: Early vs. Delayed Dialysis in Acute Kidney Injury (link to abstract and commentaries)

Source: Critical Care Reviews Newsletter

7 – Pleural Effusion in Adults—Etiology, Diagnosis, and Treatment – Deutsches Ärzteblatt international (free)

Source: Critical Care Reviews Newsletter

8 – Association of a Multifaceted Intervention With Ordering of Unnecessary Laboratory Tests Among Caregivers in Internal Medicine Departments – JAMA Network Open (free)

9 – Association of Normal-Weight Central Obesity With All-Cause and Cause-Specific Mortality Among Postmenopausal Women – JAMA Network Open (free)

Commentaries: What’s New in Understanding the Risk Associated With Body Size and Shape? Pears, Apples, and Olives on Toothpicks – JAMA Network Open (free) AND Bellyfat in some postmenopausal women linked to higher death risk – UPI (free) AND Expert reaction to central obesity and mortality risk in postmenopausal women of normal weight – Science Media Centre (free)

Related Study: Distribution of Regional Body Fat and Cardiovascular Disease Risk Among Postmenopausal Women with Normal BMI (free study and commentaries)

10 – Quantifying the impact of the Public Health Responsibility Deal on salt intake, cardiovascular disease and gastric cancer burdens: interrupted time series and microsimulation study – Journal of Epidemiology & Community Health (free)

Commentaries: Stricter Regulations Needed to Maximize Cuts in Sodium Intake, UK Study Suggests – TCTMD (free) AND Relaxed UK salt policy tied to more heart disease, cancers – Reuters (free)

Preventing Dementia by Preventing Stroke: The Berlin Manifesto

25 Jul, 2019 | 01:59h | UTC

Preventing dementia by preventing stroke: The Berlin Manifesto – Alzheimer’s & Dementia (free)

Commentaries: Group calls on international community to prevent dementia by preventing stroke – University of Western Ontario (free) AND Stroke Prevention Best Path to Dementia Reduction, Experts Say – Medscape (free registration required)

Study: Stress Testing–Induced Myocardial Ischemia is Not Corelated with Prognosis in Patients with Stable Multivessel Coronary Artery Disease

25 Jul, 2019 | 01:57h | UTC

Association Between Stress Testing–Induced Myocardial Ischemia and Clinical Events in Patients With Multivessel Coronary Artery Disease – JAMA Internal Medicine (free)

Commentary: Baseline Ischemia Not Linked to 10-Year Events in Stable CAD: MASS II Analysis – TCTMD (free) AND Stress Testing–Induced Myocardial Ischemia and Clinical Events in Multivessel CAD – Latest in Cardiology (free)

How a Data Detective Exposed Suspicious Medical Trials

25 Jul, 2019 | 01:56h | UTC

How a data detective exposed suspicious medical trials – Nature (free)

Related: Dozens of recent clinical trials may contain wrong or falsified data (free study by John Carlisle)

“Anaesthetist John Carlisle has spotted problems in hundreds of research papers — and spurred a leading medical journal to change its practice.”

Allergan Recalls Textured Breast Implant Tied to Rare Cancer

25 Jul, 2019 | 01:54h | UTC

Allergan Recalls Textured Breast Implant Tied to Rare Cancer – Associated Press (free)

Related: FDA Report: 660 Cases of Breast Implant-Associated Anaplastic Large Cell Lymphoma (link to statement and other studies)

Review: Renal Replacement Therapy in the Critical Care Setting

25 Jul, 2019 | 01:51h | UTC

Renal Replacement Therapy in the Critical Care Setting – Critical Care Research and Practice (free)

Related Randomized Trial: Early vs. Delayed Dialysis in Acute Kidney Injury (link to abstract and commentaries)

Source: Critical Care Reviews Newsletter

Large Observational Study Suggests One Dose of HPV Vaccine May Be as Effective as Three

25 Jul, 2019 | 01:53h | UTC

Is one dose of human papillomavirus vaccine as effective as three?: A national cohort analysis – Papillomavirus Research (free)

Commentary: One dose of HPV vaccine may be enough, Australian research finds – University of Melbourne (free)

Cohort Study: Association of Normal-Weight Central Obesity with All-Cause and Cause-Specific Mortality Among Postmenopausal Women

25 Jul, 2019 | 01:45h | UTC

Association of Normal-Weight Central Obesity With All-Cause and Cause-Specific Mortality Among Postmenopausal Women – JAMA Network Open (free)

Commentaries: What’s New in Understanding the Risk Associated With Body Size and Shape? Pears, Apples, and Olives on Toothpicks – JAMA Network Open (free) AND Bellyfat in some postmenopausal women linked to higher death risk – UPI (free) AND Expert reaction to central obesity and mortality risk in postmenopausal women of normal weight – Science Media Centre (free)

Pleural Effusion in Adults—Etiology, Diagnosis, and Treatment

25 Jul, 2019 | 01:49h | UTC

Pleural Effusion in Adults—Etiology, Diagnosis, and Treatment – Deutsches Ärzteblatt international (free)

Source: Critical Care Reviews Newsletter

Multifaceted Intervention Associated with Reduced Ordering of Unnecessary Laboratory Tests Among Caregivers in Internal Medicine Departments

25 Jul, 2019 | 01:48h | UTC

Association of a Multifaceted Intervention With Ordering of Unnecessary Laboratory Tests Among Caregivers in Internal Medicine Departments – JAMA Network Open (free)

Study: Relaxed Regulations in Salt Policy May Increase the Burden of Cardiovascular Diseases

25 Jul, 2019 | 01:43h | UTC

Quantifying the impact of the Public Health Responsibility Deal on salt intake, cardiovascular disease and gastric cancer burdens: interrupted time series and microsimulation study – Journal of Epidemiology & Community Health (free)

Commentaries: Stricter Regulations Needed to Maximize Cuts in Sodium Intake, UK Study Suggests – TCTMD (free) AND Relaxed UK salt policy tied to more heart disease, cancers – Reuters (free)

[Abstract Only] Study: Crowding in the Emergency Department Linked to Increased Mortality in Discharged Patients

25 Jul, 2019 | 01:25h | UTC

Associations Between Crowding and Ten-Day Mortality Among Patients Allocated Lower Triage Acuity Levels Without Need of Acute Hospital Care on Departure From the Emergency Department – Annals of Emergency Medicine (link to abstract – $ for full-text)

Commentary: Does Crowding Increase Mortality In Low-Acuity Discharged Patients? – JournalFeed (free)

Systematic Review: Palliative Care for People with Dementia Living at Home

25 Jul, 2019 | 01:32h | UTC

Palliative care for people with dementia living at home: A systematic review of interventions – Palliative Medicine (free)

Perspective: The Superbug Candida Auris is Giving Rise to Warnings — and Big Questions

25 Jul, 2019 | 01:24h | UTC

The superbug Candida auris is giving rise to warnings — and big questions – STAT (free)

Related: Global Epidemiology of Emerging Candida Auris (reviews and commentaries on the subject)