Archives
Systematic Review: Beta-blockers to Prevent Death or Serious Events After Non-Cardiac Surgery
27 Sep, 2019 | 08:30h | UTCPerioperative beta‐blockers for preventing surgery‐related mortality and morbidity in adults undergoing non‐cardiac surgery – Cochrane Library (free)
Summary: Beta-blockers to prevent death or serious events after surgery not involving the heart – Cochrane Library (free)
Evidence Synthesis: Should Antidepressants be Used for Major Depressive Disorder?
27 Sep, 2019 | 08:33h | UTCShould antidepressants be used for major depressive disorder? – BMJ Evidence-Based Medicine (free)
Related Meta-analysis: Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis – The Lancet (free)
Related Commentary: Do Antidepressants Work? – The New York Times (10 articles per month are free)
“Generally, all the previous reviews show that antidepressants seem to have statistically significant effects on depressive symptoms, but the size of the effect has questionable importance to most patients.”
Clinical Approach to Lactose Intolerance
27 Sep, 2019 | 08:31h | UTCClinical Approach to Lactose Intolerance – JAMA (free for a limited period)
Related Reviews: Update on lactose malabsorption and intolerance: pathogenesis, diagnosis and clinical management – Gut (free) AND Lactose Intolerance, Dairy Avoidance, and Treatment Options – Nutrients (free)
Study: BCG Vaccination in Childhood Associated with Reduced Risk of Lung Cancer
27 Sep, 2019 | 08:24h | UTCCommentaries: BCG Vaccination and Cancer Risk: What’s the Link? – MPR (free) AND BCG Vax: A Shot Against Lung Cancer in Native Populations? – MedPage Today (free registration required)
ACOG Committee Opinion: Over-the-Counter Access to Hormonal Contraception
27 Sep, 2019 | 08:28h | UTCSummary: Over-the-Counter Access to Hormonal Contraception (free)
News Release: ACOG Updates Guidance on Over-the-Counter Access to Hormonal Contraception (free)
Commentaries: Hormonal Contraceptives Should Be Available OTC, ACOG Recommends – NEJM Journal Watch (free) AND All hormonal birth control should be available over the counter, OB-GYN group says – NBC News (free)
[Abstract Only] Randomized Trial: Total Hip Arthroplasty or Hemiarthroplasty for Hip Fracture
27 Sep, 2019 | 08:26h | UTCTotal Hip Arthroplasty or Hemiarthroplasty for Hip Fracture – New England Journal of Medicine (free)
Commentary: International study finds similar results from total or partial hip replacement – McMaster University (free)
[Abstract Only] Randomized Trial: Dual Antiplatelet Therapy vs. Monotherapy with a P2Y12 Inhibitor in High-Risk Patients after PCI
27 Sep, 2019 | 08:25h | UTCTicagrelor with or without Aspirin in High-Risk Patients after PCI – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Ticagrelor With Aspirin or Alone in High-Risk Patients After Coronary Intervention – TWILIGHT – American College of Cardiology (free) AND TWILIGHT: Ticagrelor Monotherapy Lowers Bleeding Without Increasing Ischemic Events – TCTMD (free)
This is How Attitudes to Vaccines Compare Around the World
27 Sep, 2019 | 08:23h | UTCThis is how attitudes to vaccines compare around the world – World Economic Forum (free)
Systematic Review: Effect of Organization-Directed Workplace Interventions on Physician Burnout
27 Sep, 2019 | 08:22h | UTCRelated: Physician Burnout: A Global Crisis (several resources on the subject)
Thu September 26 – 10 Stories of The Day!
26 Sep, 2019 | 10:44h | UTC
Commentaries: Human versus machine in medicine: can scientific literature answer the question? – The Lancet Digital Health (free) AND First systematic review and meta-analysis suggests artificial intelligence may be as effective as health professionals at diagnosing disease – The Lancet (free) AND Can AI really interpret images as well as physicians? – Health Imaging (free) AND Expert reaction to a study looking at the effectiveness of AI at diagnosing disease compared to health professionals – Science Media Centre (free)
Commentaries: Outcomes of birth options after a previous Cesarean section – PLOS (free) AND Repeat C-sections safer option for some women – OnMedica (free)
Commentaries: First-of-its-kind guideline sets out best practices for delivering injectable opioid agonist treatment – The University of British Columbia (free) AND New national guideline sets out best practices for delivering injectable opioid agonist treatment – Canadian Medical Association Journal (free)
7 – Step-Up Therapy in Black Children and Adults with Poorly Controlled Asthma – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Study assesses asthma treatment options in African American children and adults – NIH News Release (free)
8 – Alex Nowbar’s journal review, 24 September 2019 – The BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.
Commentaries: Boosting daily nut consumption linked to less weight gain and lower obesity risk – The BMJ (free) AND Higher daily nut consumption linked to lower weight gain – OnMedica (free) AND Eating more nuts may help prevent weight gain – Medical News Today (free)
10 – High-Intensity Versus Low-Intensity Surveillance for Patients With Colorectal Adenomas: A Cost-Effectiveness Analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Model supports high-intensity surveillance after detection of colorectal adenomas – ACP Internist (free) AND High-intensity surveillance colonoscopy reduces CRC risk, is cost-effective for patients with colorectal adenomas – American College of Physicians (free)
Meta-Analysis: Performance of Deep Learning Algorithms vs. Health-care Professionals in Detecting Diseases from Medical Imaging
26 Sep, 2019 | 08:46h | UTCCommentaries: Human versus machine in medicine: can scientific literature answer the question? – The Lancet Digital Health (free) AND First systematic review and meta-analysis suggests artificial intelligence may be as effective as health professionals at diagnosing disease – The Lancet (free) AND Can AI really interpret images as well as physicians? – Health Imaging (free) AND Expert reaction to a study looking at the effectiveness of AI at diagnosing disease compared to health professionals – Science Media Centre (free)
Report: State of the Clinical Science of Perioperative Brain Health
26 Sep, 2019 | 08:43h | UTC
Cohort Study: After a Previous Cesarean Surgery, Attempting a Vaginal Birth is Associated with Increased Risk of Serious Adverse Maternal and Perinatal Outcomes
26 Sep, 2019 | 08:45h | UTCCommentaries: Outcomes of birth options after a previous Cesarean section – PLOS (free) AND Repeat C-sections safer option for some women – OnMedica (free)
Guideline: Injectable Opioid Agonist Treatment for Opioid Use Disorder
26 Sep, 2019 | 08:40h | UTCCommentaries: First-of-its-kind guideline sets out best practices for delivering injectable opioid agonist treatment – The University of British Columbia (free) AND New national guideline sets out best practices for delivering injectable opioid agonist treatment – Canadian Medical Association Journal (free)
Alex Nowbar’s journal review—24 September 2019
26 Sep, 2019 | 08:32h | UTCAlex Nowbar’s journal review, 24 September 2019 – The BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.
Meta-analysis: Therapies for Preventing Cardiotoxicity in Patients Undergoing Chemotherapy
26 Sep, 2019 | 08:35h | UTC
Related Commentary on Twitter
Efficacy of Neurohormonal Therapies to Prevent Cardiotoxicity in Pts w/ Cancer
Featured in Inaugural Issue @JACCJournals
#JACCCardioOnc w/@Hirji1987 @ambarish4786Meta-analysis (n=17): ~4% attenuation of LVEF decline, unmet need for large powered RCTshttps://t.co/TCC4NnxQli pic.twitter.com/G1yLF4b83T
— Muthu Vaduganathan (@mvaduganathan) September 24, 2019
European Guidelines for Diagnosing Celiac Disease
26 Sep, 2019 | 08:36h | UTC
[Abstract Only] Randomized Trial: Step-Up Therapy in Black Children and Adults with Poorly Controlled Asthma
26 Sep, 2019 | 08:33h | UTCStep-Up Therapy in Black Children and Adults with Poorly Controlled Asthma – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Study assesses asthma treatment options in African American children and adults – NIH News Release (free)
Cohort Studies: Increasing Nut Consumption Associated with Less Weight Gain and Lower Risk of Obesity
26 Sep, 2019 | 08:31h | UTCCommentaries: Boosting daily nut consumption linked to less weight gain and lower obesity risk – The BMJ (free) AND Higher daily nut consumption linked to lower weight gain – OnMedica (free) AND Eating more nuts may help prevent weight gain – Medical News Today (free)
Wed September 25 – 10 Stories of The Day!
25 Sep, 2019 | 10:35h | UTC
Editorials: Updated Guidelines for Screening for Asymptomatic Bacteriuria (free) AND The 2019 USPSTF Report on Screening for Asymptomatic Bacteriuria—Lessons From History (free)
Author Interview: USPSTF Recommendation: Screening for Asymptomatic Bacteriuria in Adults (free audio)
2 – Guideline Synopsis: Prevention and Management of Venous Thromboembolism – JAMA (free for a limited period)
Clinical Review Audio: An Update on the Diagnosis and Treatment of Venous Thromboembolic Disease (free)
Original American Society of Hematology 2018 Guidelines: Prophylaxis for hospitalized and nonhospitalized medical patients (free) AND Diagnosis of venous thromboembolism (free) AND Optimal management of anticoagulation therapy (free) AND Treatment of pediatric venous thromboembolism (free) AND Venous thromboembolism in the context of pregnancy (free) AND Heparin-induced thrombocytopenia (free)
Commentaries: For young athletes, sport specialization means increased risk of injury – Brown University (free) AND Sports Specialization Hurts Girls More Than Boys – MedicalResearch.com (free)
Related Meta-Analysis: Sport Specialization and Risk of Overuse Injuries (link to abstract and commentary)
6 – A Simple Regimen Can Prevent TB. Why Aren’t More People on It? – The New York Times (10 articles per month are free)
Related Randomized Trial: One Month of Rifapentine plus Isoniazid vs. 9 months of Isoniazid Alone for Preventing Tuberculosis in HIV-infected Patients with Latent Tuberculosis Infection (free)
7 – Age to stop? Appropriate screening in older patients – Canadian Family Physician (free)
Editorial: Preventive care at both ends of life (free)
Podcast: Appropriate screening in older patients (free audio)
Source: Canadian Task Force on Preventive Health Care Newsletter
8 – Finding the Right Words to Stop Cancer Screening in Older Adults – JAMA (free)
Related Study: Older Adults’ Views and Communication Preferences About Cancer Screening Cessation – JAMA Internal Medicine (free)
9 – Acute ischaemic stroke: challenges for the intensivist – Intensive Care Medicine (free)
Source: Critical Care Reviews Newsletter
[Abstract Only] Cost-Effectiveness Analysis: High-Intensity Versus Low-Intensity Surveillance for Patients with Colorectal Adenomas
26 Sep, 2019 | 08:29h | UTCHigh-Intensity Versus Low-Intensity Surveillance for Patients With Colorectal Adenomas: A Cost-Effectiveness Analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Model supports high-intensity surveillance after detection of colorectal adenomas – ACP Internist (free) AND High-intensity surveillance colonoscopy reduces CRC risk, is cost-effective for patients with colorectal adenomas – American College of Physicians (free)
Guideline Synopsis: Prevention and Management of Venous Thromboembolism
25 Sep, 2019 | 08:33h | UTCPrevention and Management of Venous Thromboembolism – JAMA (free for a limited period)
Clinical Review Audio: An Update on the Diagnosis and Treatment of Venous Thromboembolic Disease (free)
Original American Society of Hematology 2018 Guidelines: Prophylaxis for hospitalized and nonhospitalized medical patients (free) AND Diagnosis of venous thromboembolism (free) AND Optimal management of anticoagulation therapy (free) AND Treatment of pediatric venous thromboembolism (free) AND Venous thromboembolism in the context of pregnancy (free) AND Heparin-induced thrombocytopenia (free)
Position Paper: Withholding and Withdrawing Life-support in Adults in Emergency Care
25 Sep, 2019 | 08:31h | UTC
USPSTF Recommendation Statement: Screening for Asymptomatic Bacteriuria in Adults
25 Sep, 2019 | 08:35h | UTCEditorials: Updated Guidelines for Screening for Asymptomatic Bacteriuria (free) AND The 2019 USPSTF Report on Screening for Asymptomatic Bacteriuria—Lessons From History (free)
Author Interview: USPSTF Recommendation: Screening for Asymptomatic Bacteriuria in Adults (free audio)
Meta-Analysis: Effects of Antihypertensives, Lipid-modifying Drugs, Glycemic Control Drugs and Sodium Bicarbonate on the Progression of Chronic Kidney Disease
25 Sep, 2019 | 08:28h | UTC


