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Systematic Review: Beta-blockers to Prevent Death or Serious Events After Non-Cardiac Surgery

27 Sep, 2019 | 08:30h | UTC

Perioperative beta‐blockers for preventing surgery‐related mortality and morbidity in adults undergoing non‐cardiac surgery – Cochrane Library (free)

Summary: Beta-blockers to prevent death or serious events after surgery not involving the heart – Cochrane Library (free)

 


Evidence Synthesis: Should Antidepressants be Used for Major Depressive Disorder?

27 Sep, 2019 | 08:33h | UTC

Should antidepressants be used for major depressive disorder? – BMJ Evidence-Based Medicine (free)

Related Meta-analysis: Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis – The Lancet (free)

Related Commentary: Do Antidepressants Work? – The New York Times (10 articles per month are free)

“Generally, all the previous reviews show that antidepressants seem to have statistically significant effects on depressive symptoms, but the size of the effect has questionable importance to most patients.”

 


Clinical Approach to Lactose Intolerance

27 Sep, 2019 | 08:31h | UTC

Clinical Approach to Lactose Intolerance – JAMA (free for a limited period)

Related Reviews: Update on lactose malabsorption and intolerance: pathogenesis, diagnosis and clinical management – Gut (free) AND Lactose Intolerance, Dairy Avoidance, and Treatment Options – Nutrients (free)

 


Study: BCG Vaccination in Childhood Associated with Reduced Risk of Lung Cancer

27 Sep, 2019 | 08:24h | UTC

Association of BCG Vaccination in Childhood With Subsequent Cancer Diagnoses: A 60-Year Follow-up of a Clinical Trial – JAMA Network Open (free)

Commentaries: BCG Vaccination and Cancer Risk: What’s the Link? – MPR (free) AND BCG Vax: A Shot Against Lung Cancer in Native Populations? – MedPage Today (free registration required)

 


ACOG Committee Opinion: Over-the-Counter Access to Hormonal Contraception

27 Sep, 2019 | 08:28h | UTC

Over-the-Counter Access to Hormonal Contraception – American College of Obstetricians and Gynecologists (free)

Summary: Over-the-Counter Access to Hormonal Contraception (free)

News Release: ACOG Updates Guidance on Over-the-Counter Access to Hormonal Contraception (free)

Commentaries: Hormonal Contraceptives Should Be Available OTC, ACOG Recommends – NEJM Journal Watch (free) AND All hormonal birth control should be available over the counter, OB-GYN group says – NBC News (free)

 


[Abstract Only] Randomized Trial: Total Hip Arthroplasty or Hemiarthroplasty for Hip Fracture

27 Sep, 2019 | 08:26h | UTC

Total Hip Arthroplasty or Hemiarthroplasty for Hip Fracture – New England Journal of Medicine (free)

Commentary: International study finds similar results from total or partial hip replacement – McMaster University (free)

 


[Abstract Only] Randomized Trial: Dual Antiplatelet Therapy vs. Monotherapy with a P2Y12 Inhibitor in High-Risk Patients after PCI

27 Sep, 2019 | 08:25h | UTC

Ticagrelor with or without Aspirin in High-Risk Patients after PCI – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Ticagrelor With Aspirin or Alone in High-Risk Patients After Coronary Intervention – TWILIGHT – American College of Cardiology (free) AND TWILIGHT: Ticagrelor Monotherapy Lowers Bleeding Without Increasing Ischemic Events – TCTMD (free)

 


This is How Attitudes to Vaccines Compare Around the World

27 Sep, 2019 | 08:23h | UTC

This is how attitudes to vaccines compare around the world – World Economic Forum (free)

 


Systematic Review: Effect of Organization-Directed Workplace Interventions on Physician Burnout

27 Sep, 2019 | 08:22h | UTC

Effect of Organization-Directed Workplace Interventions on Physician Burnout: A Systematic Review – Mayo Clinic Proceedings: Innovations, Quality & Outcomes (free)

Related: Physician Burnout: A Global Crisis (several resources on the subject)

 


Thu September 26 – 10 Stories of The Day!

26 Sep, 2019 | 10:44h | UTC

 

1 – A comparison of deep learning performance against health-care professionals in detecting diseases from medical imaging: a systematic review and meta-analysis – The Lancet Digital Health (free)

Commentaries: Human versus machine in medicine: can scientific literature answer the question? – The Lancet Digital Health (free) AND First systematic review and meta-analysis suggests artificial intelligence may be as effective as health professionals at diagnosing disease – The Lancet (free) AND Can AI really interpret images as well as physicians? – Health Imaging (free) AND Expert reaction to a study looking at the effectiveness of AI at diagnosing disease compared to health professionals – Science Media Centre (free)

 

2 – Planned mode of delivery after previous cesarean section and short-term maternal and perinatal outcomes: A population-based record linkage cohort study in Scotland – PLOS Medicine (free)

Commentaries: Outcomes of birth options after a previous Cesarean section – PLOS (free) AND Repeat C-sections safer option for some women – OnMedica (free)

 

3 – State of the clinical science of perioperative brain health: report from the American Society of Anesthesiologists Brain Health Initiative Summit 2018 – British Journal of Anaesthesia (free)

Related: American Geriatrics Society Abstracted Clinical Practice Guideline for Postoperative Delirium in Older Adults – Journal of the American Geriatrics Society (free)

 

4 – Injectable opioid agonist treatment for opioid use disorder: a national clinical guideline – Canadian Medical Association Journal (free)

Commentaries: First-of-its-kind guideline sets out best practices for delivering injectable opioid agonist treatment – The University of British Columbia (free) AND New national guideline sets out best practices for delivering injectable opioid agonist treatment – Canadian Medical Association Journal (free)

 

5 – European Society for Paediatric Gastroenterology, Hepatology and Nutrition Guidelines for Diagnosing Coeliac Disease 2019 – Journal of Pediatric Gastroenterology and Nutrition (free PDF)

 

6 – Efficacy of Neurohormonal Therapies in Preventing Cardiotoxicity in Patients With Cancer Undergoing Chemotherapy – JACC CardioOncology (free)

 

7 – Step-Up Therapy in Black Children and Adults with Poorly Controlled Asthma – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Study assesses asthma treatment options in African American children and adults – NIH News Release (free)

 

8 – Alex Nowbar’s journal review, 24 September 2019 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

 

9 – Changes in nut consumption influence long-term weight change in US men and women – BMJ Nutrition, Prevention & Health (free)

Commentaries: Boosting daily nut consumption linked to less weight gain and lower obesity risk – The BMJ (free) AND Higher daily nut consumption linked to lower weight gain – OnMedica (free) AND Eating more nuts may help prevent weight gain – Medical News Today (free)

 

10 – High-Intensity Versus Low-Intensity Surveillance for Patients With Colorectal Adenomas: A Cost-Effectiveness Analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Model supports high-intensity surveillance after detection of colorectal adenomas – ACP Internist (free) AND High-intensity surveillance colonoscopy reduces CRC risk, is cost-effective for patients with colorectal adenomas – American College of Physicians (free)

 


Meta-Analysis: Performance of Deep Learning Algorithms vs. Health-care Professionals in Detecting Diseases from Medical Imaging

26 Sep, 2019 | 08:46h | UTC

A comparison of deep learning performance against health-care professionals in detecting diseases from medical imaging: a systematic review and meta-analysis – The Lancet Digital Health (free)

Commentaries: Human versus machine in medicine: can scientific literature answer the question? – The Lancet Digital Health (free) AND First systematic review and meta-analysis suggests artificial intelligence may be as effective as health professionals at diagnosing disease – The Lancet (free) AND Can AI really interpret images as well as physicians? – Health Imaging (free) AND Expert reaction to a study looking at the effectiveness of AI at diagnosing disease compared to health professionals – Science Media Centre (free)

 


Report: State of the Clinical Science of Perioperative Brain Health

26 Sep, 2019 | 08:43h | UTC

State of the clinical science of perioperative brain health: report from the American Society of Anesthesiologists Brain Health Initiative Summit 2018 – British Journal of Anaesthesia (free)

Related: American Geriatrics Society Abstracted Clinical Practice Guideline for Postoperative Delirium in Older Adults – Journal of the American Geriatrics Society (free)

 


Cohort Study: After a Previous Cesarean Surgery, Attempting a Vaginal Birth is Associated with Increased Risk of Serious Adverse Maternal and Perinatal Outcomes

26 Sep, 2019 | 08:45h | UTC

Planned mode of delivery after previous cesarean section and short-term maternal and perinatal outcomes: A population-based record linkage cohort study in Scotland – PLOS Medicine (free)

Commentaries: Outcomes of birth options after a previous Cesarean section – PLOS (free) AND Repeat C-sections safer option for some women – OnMedica (free)

 


Guideline: Injectable Opioid Agonist Treatment for Opioid Use Disorder

26 Sep, 2019 | 08:40h | UTC

Injectable opioid agonist treatment for opioid use disorder: a national clinical guideline – Canadian Medical Association Journal (free)

Commentaries: First-of-its-kind guideline sets out best practices for delivering injectable opioid agonist treatment – The University of British Columbia (free) AND New national guideline sets out best practices for delivering injectable opioid agonist treatment – Canadian Medical Association Journal (free)

 


Alex Nowbar’s journal review—24 September 2019

26 Sep, 2019 | 08:32h | UTC

Alex Nowbar’s journal review, 24 September 2019 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

 


Meta-analysis: Therapies for Preventing Cardiotoxicity in Patients Undergoing Chemotherapy

26 Sep, 2019 | 08:35h | UTC

Efficacy of Neurohormonal Therapies in Preventing Cardiotoxicity in Patients With Cancer Undergoing Chemotherapy – JACC CardioOncology (free)

 

Related Commentary on Twitter

 


European Guidelines for Diagnosing Celiac Disease

26 Sep, 2019 | 08:36h | UTC

European Society for Paediatric Gastroenterology, Hepatology and Nutrition Guidelines for Diagnosing Coeliac Disease 2019 – Journal of Pediatric Gastroenterology and Nutrition (free PDF)

 


[Abstract Only] Randomized Trial: Step-Up Therapy in Black Children and Adults with Poorly Controlled Asthma

26 Sep, 2019 | 08:33h | UTC

Step-Up Therapy in Black Children and Adults with Poorly Controlled Asthma – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Study assesses asthma treatment options in African American children and adults – NIH News Release (free)

 


Cohort Studies: Increasing Nut Consumption Associated with Less Weight Gain and Lower Risk of Obesity

26 Sep, 2019 | 08:31h | UTC

Changes in nut consumption influence long-term weight change in US men and women – BMJ Nutrition, Prevention & Health (free)

Commentaries: Boosting daily nut consumption linked to less weight gain and lower obesity risk – The BMJ (free) AND Higher daily nut consumption linked to lower weight gain – OnMedica (free) AND Eating more nuts may help prevent weight gain – Medical News Today (free)

 


Wed September 25 – 10 Stories of The Day!

25 Sep, 2019 | 10:35h | UTC

 

1 – Final Recommendation Statement: Screening for Asymptomatic Bacteriuria in Adults – U.S. Preventive Services Task Force (free)

Editorials: Updated Guidelines for Screening for Asymptomatic Bacteriuria (free) AND The 2019 USPSTF Report on Screening for Asymptomatic Bacteriuria—Lessons From History (free)

Author Interview: USPSTF Recommendation: Screening for Asymptomatic Bacteriuria in Adults (free audio)

 

2 – Guideline Synopsis: Prevention and Management of Venous Thromboembolism – JAMA (free for a limited period)

Clinical Review Audio: An Update on the Diagnosis and Treatment of Venous Thromboembolic Disease (free)

Original American Society of Hematology 2018 Guidelines: Prophylaxis for hospitalized and nonhospitalized medical patients (free) AND Diagnosis of venous thromboembolism (free) AND Optimal management of anticoagulation therapy (free) AND Treatment of pediatric venous thromboembolism (free) AND Venous thromboembolism in the context of pregnancy (free) AND Heparin-induced thrombocytopenia (free)

 

3 – Withholding and withdrawing life-support in adults in emergency care: joint position paper from the French Intensive Care Society and French Society of Emergency Medicine – Annals of Intensive Care (free)

 

4 – Injury Risk Associated with Sports Specialization and Activity Volume in Youth – Orthopaedic Journal of Sports Medicine (free)

Commentaries: For young athletes, sport specialization means increased risk of injury – Brown University (free) AND Sports Specialization Hurts Girls More Than Boys – MedicalResearch.com (free)

Related Meta-Analysis: Sport Specialization and Risk of Overuse Injuries (link to abstract and commentary)

 

5 – Effects of antihypertensives, lipid-modifying drugs, glycaemic control drugs and sodium bicarbonate on the progression of stages 3 and 4 chronic kidney disease in adults: a systematic review and meta-analysis – BMJ Open (free)

 

6 – A Simple Regimen Can Prevent TB. Why Aren’t More People on It? – The New York Times (10 articles per month are free)

Related Randomized Trial: One Month of Rifapentine plus Isoniazid vs. 9 months of Isoniazid Alone for Preventing Tuberculosis in HIV-infected Patients with Latent Tuberculosis Infection (free)

 

7 – Age to stop? Appropriate screening in older patients – Canadian Family Physician (free)

Editorial: Preventive care at both ends of life (free)

Podcast: Appropriate screening in older patients (free audio)

Source: Canadian Task Force on Preventive Health Care Newsletter

 

8 – Finding the Right Words to Stop Cancer Screening in Older Adults – JAMA (free)

Related Study: Older Adults’ Views and Communication Preferences About Cancer Screening Cessation – JAMA Internal Medicine (free)

 

9 – Acute ischaemic stroke: challenges for the intensivist – Intensive Care Medicine (free)

Source: Critical Care Reviews Newsletter

 

10 – Inherited Thrombophilia and the Risk of Arterial Ischemic Stroke: A Systematic Review and Meta‐Analysis – Journal of the American Heart Association (free)

 


[Abstract Only] Cost-Effectiveness Analysis: High-Intensity Versus Low-Intensity Surveillance for Patients with Colorectal Adenomas

26 Sep, 2019 | 08:29h | UTC

High-Intensity Versus Low-Intensity Surveillance for Patients With Colorectal Adenomas: A Cost-Effectiveness Analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Model supports high-intensity surveillance after detection of colorectal adenomas – ACP Internist (free) AND High-intensity surveillance colonoscopy reduces CRC risk, is cost-effective for patients with colorectal adenomas – American College of Physicians (free)

 


Guideline Synopsis: Prevention and Management of Venous Thromboembolism

25 Sep, 2019 | 08:33h | UTC

Prevention and Management of Venous Thromboembolism – JAMA (free for a limited period)

Clinical Review Audio: An Update on the Diagnosis and Treatment of Venous Thromboembolic Disease (free)

Original American Society of Hematology 2018 Guidelines: Prophylaxis for hospitalized and nonhospitalized medical patients (free) AND Diagnosis of venous thromboembolism (free) AND Optimal management of anticoagulation therapy (free) AND Treatment of pediatric venous thromboembolism (free) AND Venous thromboembolism in the context of pregnancy (free) AND Heparin-induced thrombocytopenia (free)

 


Position Paper: Withholding and Withdrawing Life-support in Adults in Emergency Care

25 Sep, 2019 | 08:31h | UTC

Withholding and withdrawing life-support in adults in emergency care: joint position paper from the French Intensive Care Society and French Society of Emergency Medicine – Annals of Intensive Care (free)

 


USPSTF Recommendation Statement: Screening for Asymptomatic Bacteriuria in Adults

25 Sep, 2019 | 08:35h | UTC

Final Recommendation Statement: Screening for Asymptomatic Bacteriuria in Adults – U.S. Preventive Services Task Force (free)

Editorials: Updated Guidelines for Screening for Asymptomatic Bacteriuria (free) AND The 2019 USPSTF Report on Screening for Asymptomatic Bacteriuria—Lessons From History (free)

Author Interview: USPSTF Recommendation: Screening for Asymptomatic Bacteriuria in Adults (free audio)

 


Meta-Analysis: Effects of Antihypertensives, Lipid-modifying Drugs, Glycemic Control Drugs and Sodium Bicarbonate on the Progression of Chronic Kidney Disease

25 Sep, 2019 | 08:28h | UTC

Effects of antihypertensives, lipid-modifying drugs, glycaemic control drugs and sodium bicarbonate on the progression of stages 3 and 4 chronic kidney disease in adults: a systematic review and meta-analysis – BMJ Open (free)

 


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