Archives
Systematic Review: Higher vs. Lower Fraction of Inspired Oxygen or Targets of Arterial Oxygenation for Adults Admitted to the Intensive Care Unit
29 Nov, 2019 | 08:32h | UTCHigher versus lower fraction of inspired oxygen or targets of arterial oxygenation for adults admitted to the intensive care unit – Cochrane Library (free)
Summary: Supplemental oxygen for adults admitted to the intensive care unit – Cochrane Library (free)
Related: Oxygen therapy for acutely ill medical patients: a clinical practice guideline – The BMJ (free) AND Oxygen Treatment in Intensive Care and Emergency Medicine – Deutsches Ärzteblatt International (free) AND Meta-Analysis: Liberal vs Conservative Oxygen Therapy in Acutely ill Adults (link to abstract and commentary) AND A Systematic Review of the Effects of Hyperoxia in Acutely Ill Patients: Should We Aim for Less? – BioMed Research International (free) AND Things We Do For No Reason: Supplemental Oxygen for Patients without Hypoxemia – Journal of Hospital Medicine (free)
Meta-Analysis: The Clinical Efficacy and Safety of Vancomycin Loading Dose
29 Nov, 2019 | 08:09h | UTCRelated: Vancomycin Therapeutic Guidelines: A Summary of Consensus Recommendations from the Infectious Diseases Society of America, the American Society of Health-System Pharmacists, and the Society of Infectious Diseases Pharmacists – Clinical Infectious Diseases (free) AND Therapeutic drug monitoring of vancomycin: a guideline of the Division of Therapeutic Drug Monitoring, Chinese Pharmacological Society – Journal of Antimicrobial Therapy (free) AND Practice Guidelines for Therapeutic Drug Monitoring of Vancomycin: A Consensus Review of the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring – Journal of Infection and Chemotherapy (free PDF)
Ten-year Outcomes in Men with Localized Prostate Cancer from the ProtecT Randomized Controlled Trial According to Treatment Received
29 Nov, 2019 | 08:24h | UTCOriginal Study: 10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer – New England Journal of Medicine (free)
Related Commentary on Twitter
Ten-year Mortality, Disease Progression, and Treatment-related Side Effects in Men with Localised Prostate Cancer from the ProtecT Randomised Controlled Trial According to Treatment Received@Freddie_Hamdy @JimCatto https://t.co/sNfevwU3R4 pic.twitter.com/uqnoZUgSRm
— European Urology (@EUplatinum) November 25, 2019
Post-extubation Dysphagia: A Problem Needing Multidisciplinary Efforts
29 Nov, 2019 | 07:55h | UTCPost-extubation dysphagia: a problem needing multidisciplinary efforts – Intensive Care Medicine (free for a limited period)
Related: Dysphagia in the intensive care unit: epidemiology, mechanisms, and clinical management – Critical Care (free)
Bridging Anticoagulation Therapy: A Teachable Moment
29 Nov, 2019 | 07:37h | UTCBridging Anticoagulation Therapy: A Teachable Moment – JAMA Internal Medicine (free for a limited period)
Related: 2017 ACC Expert Consensus Decision Pathway for Periprocedural Management of Anticoagulation in Patients With Nonvalvular Atrial Fibrillation (free) AND Bridging Anticoagulation: Primum Non Nocere – Journal of the American College of Cardiology (free) AND Periprocedural heparin bridging in patients receiving oral anticoagulation: a systematic review and meta-analysis – BMC Cardiovascular Disorders (free) AND Perioperative Bridging Anticoagulation in Patients with Atrial Fibrillation – New England Journal of Medicine (free)
Thu November 28 – 10 Stories of The Day!
28 Nov, 2019 | 10:51h | UTC
1 – Diagnosis of Pulmonary Embolism with d-Dimer Adjusted to Clinical Probability – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Diagnosis of Pulmonary Embolism – American College of Cardiology (free)
2 – Aupplemental MRI Screening for Women with Extremely Dense Breast Tissue – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Does MRI Screening Benefit Women With Extremely Dense Breasts? – U.S. News (free) AND Mixed Results With Mammo Plus MRI Screening – MedPage Today (free)
“The benefits need to be carefully weighed against the harms, as MRI examination is more expensive, and it requires the injection of a contrast agent into the body. MRI will also detect abnormalities that later turn out not to be breast cancer after all” (from U.S News)
3 – Randomized Trial of Three Anticonvulsant Medications for Status Epilepticus – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Head-to-head comparison finds three anti-seizure drugs equally effective for severe form of epilepsy – NIH News Release (free)
Commentary: Depression in Docs Leads to Medical Errors and Vice Versa – Medscape (free registration required)
Commentaries: WHO Releases New HIV Testing Guidelines To Help Expand Treatment Coverage, Reduce HIV Transmission – Health Policy Watch (free) AND WHO releases new HIV testing guidelines – Global ID News (free)
Related: Immune Thrombocytopenia – Current Diagnostics and Therapy: Recommendations of a Joint Working Group of DGHO, ÖGHO, SGH, GPOH, and DGTI – Oncology Research and Treatment (free) AND Clinical updates in adult immune thrombocytopenia – Blood (free) AND Management of immune thrombocytopenia: Korean experts recommendation in 2017 – Blood Research (free)
Commentaries: FDA’s Warning On CBD: Cannabis Stocks Drop, Companies Object – Forbes (free) AND ‘CBD has the potential to harm you,’ FDA warns consumers – MarketWatch (free)
Related: Cannabidiol Products Are Everywhere, but Should People Be Using Them? – JAMA (free for a limited period) AND NICE Guideline: Cannabis-Based Medicinal Products (free Guideline and other resources)
8 – What Are the Benefits of Probiotics? – The New York Times (free)
Related: Systematic Review: Harms Reporting in Trials with Probiotics (link to abstract and commentaries) AND The Problem With Probiotics – The New York Times (free)
9 – News Release: Antibiotic-Resistant Bacteria More Prevalent in Device-Related Infections – Society for Healthcare Epidemiology of America (free)
Original Studies: Antimicrobial-resistant pathogens associated with adult healthcare-associated infections: Summary of data reported to the National Healthcare Safety Network, 2015–2017 – Infection Control & Hospital Epidemiology (free) AND Antimicrobial-resistant pathogens associated with pediatric healthcare-associated infections: Summary of data reported to the National Healthcare Safety Network, 2015–2017 – Infection Control & Hospital Epidemiology (free)
Commentary: CDC: Medical devices key source of antibiotic-resistant infections – CIDRAP (free)
Related meta-analysis: Milk and dairy consumption and risk of cardiovascular diseases and all-cause mortality: dose–response meta-analysis of prospective cohort studies – European Journal of Epidemiology (free)
[Abstract Only] Randomized Trial of Three Anticonvulsant Medications for Status Epilepticus
28 Nov, 2019 | 10:36h | UTCRandomized Trial of Three Anticonvulsant Medications for Status Epilepticus – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Head-to-head comparison finds three anti-seizure drugs equally effective for severe form of epilepsy – NIH News Release (free)
Related Commentary on Twitter
Intravenous valproate, levetiracetam, and fosphenytoin stopped status epilepticus that was resistant to initial treatment with lorazepam in approximately half the patients and did not differ significantly in effectiveness. https://t.co/RfO7YKEoue
— NEJM (@NEJM) November 28, 2019
Study: Proton Pump Inhibitors May be Associated with Increased the Risk of Viral Gastroenteritis
29 Nov, 2019 | 07:46h | UTCCommentaries: Further Evidence to Monitor Long-term Proton Pump Inhibitor Use – JAMA Network Open (free) AND Prescription antacids may increase risk for stomach infections – UPI (free)
[Abstract Only] Randomized Trial: Supplemental MRI Screening vs. Usual Care with Mammography Only for Women with Extremely Dense Breast Tissue
28 Nov, 2019 | 10:39h | UTCSupplemental MRI Screening for Women with Extremely Dense Breast Tissue – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Does MRI Screening Benefit Women With Extremely Dense Breasts? – U.S. News (free) AND Mixed Results With Mammo Plus MRI Screening – MedPage Today (free)
“The benefits need to be carefully weighed against the harms, as MRI examination is more expensive, and it requires the injection of a contrast agent into the body. MRI will also detect abnormalities that later turn out not to be breast cancer after all” (from U.S News)
Related Commentary on Twitter
In this randomized trial, women with extremely dense breast tissue were invited to undergo MRI screening or received only mammography during a 2-year screening period. https://t.co/tZmcappO00
— NEJM (@NEJM) November 27, 2019
[Abstract Only] New Strategy for Diagnosing Pulmonary Embolism with D-Dimer Adjusted to Clinical Probability Could Reduce the Use of Imaging Tests
28 Nov, 2019 | 10:41h | UTCDiagnosis of Pulmonary Embolism with d-Dimer Adjusted to Clinical Probability – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Diagnosis of Pulmonary Embolism – American College of Cardiology (free)
WHO Consolidated Guidelines on HIV Testing Services for a Changing Epidemic
28 Nov, 2019 | 10:33h | UTCConsolidated guidelines on HIV testing services for a changing epidemic – World Health Organization (free)
Commentaries: WHO Releases New HIV Testing Guidelines To Help Expand Treatment Coverage, Reduce HIV Transmission – Health Policy Watch (free) AND WHO releases new HIV testing guidelines – Global ID News (free)
Consensus Report: Investigation and Management of Primary Immune Thrombocytopenia
28 Nov, 2019 | 10:31h | UTCRelated: Immune Thrombocytopenia – Current Diagnostics and Therapy: Recommendations of a Joint Working Group of DGHO, ÖGHO, SGH, GPOH, and DGTI – Oncology Research and Treatment (free) AND Clinical updates in adult immune thrombocytopenia – Blood (free) AND Management of immune thrombocytopenia: Korean experts recommendation in 2017 – Blood Research (free)
FDA Issues Safety Warning on Cannabidiol Products
28 Nov, 2019 | 10:29h | UTCCommentaries: FDA’s Warning On CBD: Cannabis Stocks Drop, Companies Object – Forbes (free) AND ‘CBD has the potential to harm you,’ FDA warns consumers – MarketWatch (free)
Related: Cannabidiol Products Are Everywhere, but Should People Be Using Them? – JAMA (free for a limited period) AND NICE Guideline: Cannabis-Based Medicinal Products (free Guideline and other resources)
Meta-Analysis: Physician Depression Associated with Medical Errors
28 Nov, 2019 | 10:35h | UTCCommentary: Depression in Docs Leads to Medical Errors and Vice Versa – Medscape (free registration required)
CDC: Antibiotic-Resistant Bacteria More Prevalent in Device-Related Infections
28 Nov, 2019 | 10:26h | UTCNews Release: Antibiotic-Resistant Bacteria More Prevalent in Device-Related Infections – Society for Healthcare Epidemiology of America (free)
Original Studies: Antimicrobial-resistant pathogens associated with adult healthcare-associated infections: Summary of data reported to the National Healthcare Safety Network, 2015–2017 – Infection Control & Hospital Epidemiology (free) AND Antimicrobial-resistant pathogens associated with pediatric healthcare-associated infections: Summary of data reported to the National Healthcare Safety Network, 2015–2017 – Infection Control & Hospital Epidemiology (free)
Commentary: CDC: Medical devices key source of antibiotic-resistant infections – CIDRAP (free)
Perspective: What Are the Benefits of Probiotics?
28 Nov, 2019 | 10:28h | UTCWhat Are the Benefits of Probiotics? – The New York Times (free)
Related: Systematic Review: Harms Reporting in Trials with Probiotics (link to abstract and commentaries) AND The Problem With Probiotics – The New York Times (free)
Cohort Study: Associations of Dairy Intake with Risk of Mortality in Women and Men
28 Nov, 2019 | 10:24h | UTCRelated meta-analysis: Milk and dairy consumption and risk of cardiovascular diseases and all-cause mortality: dose–response meta-analysis of prospective cohort studies – European Journal of Epidemiology (free)
Breast Cancer Screening and Diagnosis: A Synopsis of the European Breast Guidelines
27 Nov, 2019 | 08:19h | UTCCommentary: European guidelines for breast cancer screening differ from U.S. recommendations – ACP Internist (free)
Related: ACP Guideline: Screening for Breast Cancer in Average-Risk Women (other guidelines and commentaries on the subject)
Wed November 27 – 10 Stories of The Day!
27 Nov, 2019 | 08:40h | UTC
Commentary: European guidelines for breast cancer screening differ from U.S. recommendations – ACP Internist (free)
Related: ACP Guideline: Screening for Breast Cancer in Average-Risk Women (other guidelines on the subject)
3 – Implementation Strategies for Cardiovascular Polypills – JAMA (free for a limited period)
See also: Cardiovascular Disease Prevention at a Crossroads: Precision Medicine or Polypill? – JAMA (free)
Author Interview: Implementation Strategies for Cardiovascular Polypills (free)
Related: The Polypill Revisited: Why We Still Need Population-Based Approaches in the Precision Medicine Era (free for a limited period) AND Randomized Trial: Polypill for Cardiovascular Disease Prevention in an Underserved Population (randomized trials, commentaries and guideline on the subject)
4 – #184 Update in Sleep Medicine: LIVE from CHEST 2019! – The Curbsiders Internal Medicine Podcast (free)
Commentary: PPIs linked to adverse neurological effects – Univadis (free registration required)
Related: WHO Guidelines for Peri-Operative Hyperoxia Questioned (free)
Source: EvidenceAlerts
8 – Nonpowder Firearm Injuries to Children Treated in Emergency Departments – Pediatrics (free)
Commentaries: Pediatric eye injuries from nonpowder firearms – Nationwide Children’s Hospital (free) AND BB guns dangerous for kids as they increase risk of eye injuries – News Medical (free) AND Overall childhood injuries from nonpowder firearms are decreasing, eye injuries are increasing – 2 Minute Medicine (free)
Related: Neurosurgical Care of Nonpowder Firearm Injuries: A Narrative Review of the Literature – Emergency Medicine International (free)
9 – Long-term Outcomes of Cognitive Behavioral Therapy for Anxiety-Related Disorders: A Systematic Review and Meta-analysis – JAMA Psychiatry (free for a limited period)
10 – Follow‐up strategies following completion of primary cancer treatment in adult cancer survivors – Cochrane Library (free)
Summary: Follow-up strategies after completion of primary cancer treatment – Cochrane Library (free)
White Paper: Searching for Atrial Fibrillation Poststroke
27 Nov, 2019 | 08:21h | UTC
Podcast: Update in Sleep Medicine
27 Nov, 2019 | 08:08h | UTC#184 Update in Sleep Medicine: LIVE from CHEST 2019! – The Curbsiders Internal Medicine Podcast (free)
Viewpoint: Implementation Strategies for Cardiovascular Polypills
27 Nov, 2019 | 08:09h | UTCImplementation Strategies for Cardiovascular Polypills – JAMA (free for a limited period)
See also: Cardiovascular Disease Prevention at a Crossroads: Precision Medicine or Polypill? – JAMA (free)
Author Interview: Implementation Strategies for Cardiovascular Polypills (free)
Related: The Polypill Revisited: Why We Still Need Population-Based Approaches in the Precision Medicine Era (free for a limited period) AND Randomized Trial: Polypill for Cardiovascular Disease Prevention in an Underserved Population (randomized trials, commentaries and guideline on the subject)
Observational Study: Proton-pump Inhibitor Use is Associated with a Broad Spectrum of Neurological Adverse Events Including Impaired Hearing, Vision, and Memory
27 Nov, 2019 | 08:06h | UTCCommentary: PPIs linked to adverse neurological effects – Univadis (free registration required)
Refeeding Syndrome in the Critically Ill: a Literature Review and Clinician’s Guide
27 Nov, 2019 | 08:03h | UTC
Meta-Analysis: Comparing the Effects of Giving Perioperative Oxygen Therapy of 30% FiO2 to 80% FiO2 on Surgical Site Infection and Mortality
27 Nov, 2019 | 08:04h | UTCRelated: WHO Guidelines for Peri-Operative Hyperoxia Questioned (free)
Source: EvidenceAlerts