Archives
Fri December 13 – 10 Stories of The Day!
13 Dec, 2019 | 10:29h | UTC
News Release: AGA releases guideline on management of gastric intestinal metaplasia – American Gastroenterological Association (free)
News Release: WHO gets new advice on curbing deadly noncommunicable diseases – World Health Organization (free)
News Releases: Climate risks to health are growing but prioritized funding lacking to safeguard human health from climate change – World Health Organization (free) AND Only one in five countries has a healthcare strategy to deal with climate change – UN News (free)
Related: The 2019 Report of The Lancet Countdown on Health and Climate Change (free resources – registration required) AND Climate Change — A Health Emergency (free reports and commentaries on the subject) AND NEJM Editorial: Prioritizing Health in a Changing Climate (free commentaries) AND Climate change threatens the achievement of effective universal healthcare – The BMJ (free) AND Climate Change Is Having a Major Impact on Global Health – Scientific American (free)
4 – Effect of Fresh vs Standard-issue Red Blood Cell Transfusions on Multiple Organ Dysfunction Syndrome in Critically Ill Pediatric Patients: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Age of Red Blood Cells for Transfusion in Critically Ill Pediatric Patients (free for a limited period)
Commentaries: Fresh red blood cell transfusions do not help critically ill children more than older cells – NIH News Releases (free) AND Blood transfusions: Fresh red blood cells no better than older ones – University of Montreal (free)
5 – Perioperative care of the geriatric patient for noncardiac surgery – Clinical Cardiology (free)
Related: Optimal Perioperative Management of the Geriatric Patient: A Best Practices Guideline from the American College of Surgeons NSQIP and the American Geriatrics Society (free) AND The Perioperative Care of Older Patients: Time for a New, Interdisciplinary Approach – Deutsches Ärzteblatt international (free) AND Peri‐operative optimisation of elderly and frail patients: a narrative review – Anaesthesia (free) AND Peri-operative care of the elderly 2014: Association of Anaesthetists of Great Britain and Ireland (free)
7 – Shortened treatment regimens versus the standard regimen for drug‐sensitive pulmonary tuberculosis – Cochrane Library (free)
Summary: Shorter treatment regimens for people with pulmonary tuberculosis – Cochrane Library (free)
Commentaries: The High Burden of Sexually Transmitted Infections in Persons Initiating Preexposure Prophylaxis—Challenge or Opportunity? – JAMA Network Open (free) AND High burden of STIs in people starting treatment to prevent HIV infection – World Health Organization (free) AND STD Infections Common Among Those Starting or Staying on Prep For HIV Prevention – MedicalResearch.com (free)
9 – Effects of physical activity calorie equivalent food labelling to reduce food selection and consumption: systematic review and meta-analysis of randomised controlled studies – Journal of Epidemiology & Community Health (free)
Commentaries: Exercise advice on food labels could ‘change eating habits’ – NHS Choices (free) AND Labelling foods with physical activity needed to burn calories linked to healthier choices – The BMJ (free) AND ‘Four hours to walk off pizza calories’ warning works, experts say – BBC (free)
Commentary: Study examines the relationship between sugars and heart health – St. Michael’s Hospital (free)
[Abstract Only] Randomized Trial: Rocuronium NOT Non-inferior to Succinylcholine for Endotracheal Intubation Success Rate Among Patients Undergoing Out-of-Hospital Rapid Sequence Intubation
5 Jan, 2020 | 12:57h | UTCEffect of Rocuronium vs Succinylcholine on Endotracheal Intubation Success Rate Among Patients Undergoing Out-of-Hospital Rapid Sequence Intubation: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary: Newer Drug Falls Short for Quick Prehospital Intubation – MedPage Today (free registration required)
Related Commentary on Twitter
In this RCT, #rocuronium did not demonstrate noninferiority vs #succinylcholine in first-attempt intubation success rate in patients undergoing endotracheal intubation in out-of-hospital emergency settings. #rapidsequenceintubation https://t.co/rgw7oVVp3v
— JAMA (@JAMA_current) December 18, 2019
[Abstract Only] Randomized Trial: Aggressive Vasodilation Does Not Improve Outcomes Among Patients with Acute Heart Failure
5 Jan, 2020 | 12:53h | UTCEffect of a Strategy of Comprehensive Vasodilation vs Usual Care on Mortality and Heart Failure Rehospitalization Among Patients With Acute Heart Failure: The GALACTIC Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary: No Survival Gain From Aggressive Vasodilator Strategy in Acute HF: GALACTIC – Medscape (free registration required)
Related Commentary on Twitter
In this RCT, aggressive sustained vasodilation (nitrates, hydralazine, RAI inhibitors) didn't improve 180-d all-cause mortality or acute rehospitalizations vs usual care in patients w acute heart failure https://t.co/yzLxZAoWBx
— JAMA (@JAMA_current) December 17, 2019
It’s Time to Walk the Talk: WHO Commission on Noncommunicable Diseases Final Report
13 Dec, 2019 | 10:22h | UTCNews Release: WHO gets new advice on curbing deadly noncommunicable diseases – World Health Organization (free)
AGA Clinical Practice Guidelines on Management of Gastric Intestinal Metaplasia
13 Dec, 2019 | 10:23h | UTCAGA Clinical Practice Guidelines on Management of Gastric Intestinal Metaplasia – Gastroenterology (free PDF)
News Release: AGA releases guideline on management of gastric intestinal metaplasia – American Gastroenterological Association (free)
WHO Health and Climate Change Survey Report: Tracking Global Progress
13 Dec, 2019 | 10:21h | UTCWHO Health and Climate Change Survey Report: Tracking Global Progress – World Health Organization (free PDF)
News Releases: Climate risks to health are growing but prioritized funding lacking to safeguard human health from climate change – World Health Organization (free) AND Only one in five countries has a healthcare strategy to deal with climate change – UN News (free)
Related: The 2019 Report of The Lancet Countdown on Health and Climate Change (free resources – registration required) AND Climate Change — A Health Emergency (free reports and commentaries on the subject) AND NEJM Editorial: Prioritizing Health in a Changing Climate (free commentaries) AND Climate change threatens the achievement of effective universal healthcare – The BMJ (free) AND Climate Change Is Having a Major Impact on Global Health – Scientific American (free)
Review: Selective Decontamination of the Digestive Tract in Critically Ill Patients
13 Dec, 2019 | 10:17h | UTC
Randomized Trial: Fresh Red Blood Cell Transfusions Not Better Than Standard-issue Red Blood Cell Transfusions in Critically Ill Pediatric Patients
13 Dec, 2019 | 10:20h | UTCEffect of Fresh vs Standard-issue Red Blood Cell Transfusions on Multiple Organ Dysfunction Syndrome in Critically Ill Pediatric Patients: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Age of Red Blood Cells for Transfusion in Critically Ill Pediatric Patients (free for a limited period)
Commentaries: Fresh red blood cell transfusions do not help critically ill children more than older cells – NIH News Releases (free) AND Blood transfusions: Fresh red blood cells no better than older ones – University of Montreal (free)
Review: Perioperative Care of the Geriatric Patient for Noncardiac Surgery
13 Dec, 2019 | 10:18h | UTCPerioperative care of the geriatric patient for noncardiac surgery – Clinical Cardiology (free)
Related: Optimal Perioperative Management of the Geriatric Patient: A Best Practices Guideline from the American College of Surgeons NSQIP and the American Geriatrics Society (free) AND The Perioperative Care of Older Patients: Time for a New, Interdisciplinary Approach – Deutsches Ärzteblatt international (free) AND Peri‐operative optimisation of elderly and frail patients: a narrative review – Anaesthesia (free) AND Peri-operative care of the elderly 2014: Association of Anaesthetists of Great Britain and Ireland (free)
Study Shows High Burden of STI Among Individuals Using Preexposure Prophylaxis for the Prevention of HIV Infection
13 Dec, 2019 | 10:15h | UTCCommentaries: The High Burden of Sexually Transmitted Infections in Persons Initiating Preexposure Prophylaxis—Challenge or Opportunity? – JAMA Network Open (free) AND High burden of STIs in people starting treatment to prevent HIV infection – World Health Organization (free) AND STD Infections Common Among Those Starting or Staying on Prep For HIV Prevention – MedicalResearch.com (free)
Meta-Analysis of Cohort Studies: Relation of Total Sugars, Sucrose, Fructose, and Added Sugars With the Risk of Cardiovascular Disease
13 Dec, 2019 | 10:12h | UTCCommentary: Study examines the relationship between sugars and heart health – St. Michael’s Hospital (free)
Systematic Review: Not Enough Evidence to Recommend Shorter Treatment Regimens for People with Pulmonary TB
13 Dec, 2019 | 10:16h | UTCShortened treatment regimens versus the standard regimen for drug‐sensitive pulmonary tuberculosis – Cochrane Library (free)
Summary: Shorter treatment regimens for people with pulmonary tuberculosis – Cochrane Library (free)
Thu December 12 – 10 Stories of The Day!
12 Dec, 2019 | 08:41h | UTC
3 – European Guidelines for the treatment of HIV-positive adults – European AIDS Clinical Society (free PDF)
Source: HIV Infection Clinical Practice Guidelines (2019): European AIDS Clinical Society (EACS) – Medscape (free summary – registration required)
4 – Comorbidities in Persons With HIV: The Lingering Challenge – JAMA (free for a limited period)
Author Interview: Comorbidities in Persons With HIV (free)
Commentary: Efforts to end the HIV epidemic must not ignore people already living with HIV – NIH News Releases (free)
Commentary: High doses of vitamin D for critically ill patients yield minimal benefit – CU Anschutz Medical Campus (free)
Invited Commentary: Angiotensin-II receptor blockade in Marfan syndrome – The Lancet (free)
7 – Predatory journals: no definition, no defence – Nature (free)
Related: Many Academics Eager to Publish in Worthless Journals – The New York Times (10 articles per month are free) AND Predatory Journals Are Such a Big Problem It’s Not Even Funny – HIV and ID Observations (free)
“Leading scholars and publishers from ten countries have agreed a definition of predatory publishing that can protect scholarship. It took 12 hours of discussion, 18 questions and 3 rounds to reach.”
Commentary: Managing Dyspepsia with “Test and Treat” Ranked Best Strategy – NEJM Journal Watch (free)
9 – Prioritising action on alcohol for health and development – The BMJ (free)
See Complete Collection: Solutions for Prevention and Control of Non-communicable Diseases – WHO / The BMJ (free)
Related: WHO Global Status Report on Alcohol and Health 2018 (free report and commentaries) AND Alcohol Use and Burden for 195 Countries and Territories – The Lancet (free study and commentaries)
Editorial: Coding infections in primary care (free)
Commentaries: Up to two-fifths of antibiotic prescriptions in the US could be inappropriate – University of Bristol (free) AND Up to 43% of Antibiotic Prescriptions in the U.S. Are Unnecessary or Improperly Written, Analysis Finds – TIME (free) AND Over 40% of Antibiotic Prescriptions Potentially Inappropriate – NEJM Journal Watch (free)
Meta-Analysis of Randomized Trials: Effects of Physical Activity Calorie Equivalent Food Labelling to Reduce Food Selection and Consumption
13 Dec, 2019 | 10:13h | UTCEffects of physical activity calorie equivalent food labelling to reduce food selection and consumption: systematic review and meta-analysis of randomised controlled studies – Journal of Epidemiology & Community Health (free)
Commentaries: Exercise advice on food labels could ‘change eating habits’ – NHS Choices (free) AND Labelling foods with physical activity needed to burn calories linked to healthier choices – The BMJ (free) AND ‘Four hours to walk off pizza calories’ warning works, experts say – BBC (free)
Guideline: Duodeno-pancreatic and Extrahepatic Biliary Tree Trauma
12 Dec, 2019 | 08:30h | UTC
European Guidelines for the Treatment of HIV-positive Adults
12 Dec, 2019 | 08:29h | UTCEuropean Guidelines for the treatment of HIV-positive adults – European AIDS Clinical Society (free PDF)
Source: HIV Infection Clinical Practice Guidelines (2019): European AIDS Clinical Society (EACS) – Medscape (free summary – registration required)
ASA Practice Guidelines for Central Venous Access 2020
12 Dec, 2019 | 08:31h | UTC
Comorbidities in Persons With HIV: The Lingering Challenge
12 Dec, 2019 | 08:27h | UTCComorbidities in Persons With HIV: The Lingering Challenge – JAMA (free for a limited period)
Author Interview: Comorbidities in Persons With HIV (free)
Commentary: Efforts to end the HIV epidemic must not ignore people already living with HIV – NIH News Releases (free)
[Abstract Only] Randomized Trial: Vitamin D Not Beneficial for Critically Ill Patients
12 Dec, 2019 | 08:25h | UTCCommentaryy High doses of vitamin D for critically ill patients yield minimal benefit – CU Anschutz Medical Campus (free)
Predatory Journals: No Definition, No Defense
12 Dec, 2019 | 08:19h | UTCPredatory journals: no definition, no defence – Nature (free)
Related: Many Academics Eager to Publish in Worthless Journals – The New York Times (10 articles per month are free) AND Predatory Journals Are Such a Big Problem It’s Not Even Funny – HIV and ID Observations (free)
“Leading scholars and publishers from ten countries have agreed a definition of predatory publishing that can protect scholarship. It took 12 hours of discussion, 18 questions and 3 rounds to reach.”
Related Commentary on Twitter
Define what predatory journals actually are in order to combat them. https://t.co/c4e2oCqt89
— nature (@Nature) December 11, 2019
Study: Up to 43% of Antibiotic Prescriptions in the US Could be Inappropriate or are Improperly Documented
12 Dec, 2019 | 08:11h | UTCEditorial: Coding infections in primary care (free)
Commentaries: Up to two-fifths of antibiotic prescriptions in the US could be inappropriate – University of Bristol (free) AND Up to 43% of Antibiotic Prescriptions in the U.S. Are Unnecessary or Improperly Written, Analysis Finds – TIME (free) AND Over 40% of Antibiotic Prescriptions Potentially Inappropriate – NEJM Journal Watch (free)
Meta-Analysis: Effectiveness of Management Strategies for Uninvestigated Dyspepsia
12 Dec, 2019 | 08:15h | UTCCommentary: Managing Dyspepsia with “Test and Treat” Ranked Best Strategy – NEJM Journal Watch (free)
Related Commentary on Twitter
#BMJResearch on the effectiveness of management strategies for uninvestigated dyspepsia found that testing for H pylori and eradication treatment in those who test positive ranked first but was not superior to other strategies @alex_ford12399 https://t.co/tmpbSCfjpc
— The BMJ (@bmj_latest) December 11, 2019
Randomized Trial: Angiotensin-II Receptor Blockade Reduces the Rate of Aortic Dilatation in Patients with Marfan Syndrome
12 Dec, 2019 | 08:24h | UTCInvited Commentary: Angiotensin-II receptor blockade in Marfan syndrome – The Lancet (free)
Related Commentary on Twitter
NEW—Irbesartan is associated with a reduction in the rate of aortic dilatation in children and young adults with #Marfansyndrome and could reduce the incidence of aortic complications: finding from AIMS, double-blind, placebo-controlled randomised trial https://t.co/uVUWOC062A pic.twitter.com/FPiph5RcJu
— The Lancet (@TheLancet) December 11, 2019
Analysis: Prioritizing Action on Alcohol for Health and Development
12 Dec, 2019 | 08:13h | UTCPrioritising action on alcohol for health and development – The BMJ (free)
See Complete Collection: Solutions for Prevention and Control of Non-communicable Diseases – WHO / The BMJ (free)
Related: WHO Global Status Report on Alcohol and Health 2018 (free report and commentaries) AND Alcohol Use and Burden for 195 Countries and Territories – The Lancet (free study and commentaries)
Wed December 11 – 10 Stories of The Day!
11 Dec, 2019 | 10:41h | UTC
1 – Recommendation Statement: Screening for Abdominal Aortic Aneurysm – US Preventive Services Task Force (free)
Evidence Report: Primary Care Screening for Abdominal Aortic Aneurysm – JAMA (free)
JAMA Editorials: Updated Guidelines on Screening for Abdominal Aortic Aneurysms (free) AND Updated US Preventive Services Task Force Recommendations for Abdominal Aortic Aneurysm—Are We Really Up To Date? (free) AND Screening for Abdominal Aortic Aneurysm—A Call to Arms? (free)
Author Interview: USPSTF Recommendation: Screening for Abdominal Aortic Aneurysm (free audio)
2 – AAP Policy Statement: Unique Needs of the Adolescent – Pediatrics (free)
News Releases: American Academy of Pediatrics Describes the Unique Needs of Adolescents With New Policy Statement – American Academy of Pediatrics (free) AND AAP policy: What doctors need to consider when caring for 11- to 21-year-olds – AAP News (free)
4 – Risk of Nephrogenic Systemic Fibrosis in Patients With Stage 4 or 5 Chronic Kidney Disease Receiving a Group II Gadolinium-Based Contrast Agent: A Systematic Review and Meta-analysis – JAMA Internal Medicine (free for a limited period)
Invited Commentary: Risk of Gadolinium-Based Contrast Agents in Chronic Kidney Disease—Is Zero Good Enough? – JAMA Internal Medicine (free for a limited period)
5 – How Twitter is Changing Medical Research – Nature (free)
Related: Keeping Up With Cardiology: Old-School Learning Versus the Twittersphere – TCTMD (free) AND Scientists on Twitter: Preaching to the choir or singing from the rooftops? – Facets (free) AND Rise of the Tweetorial – Precious Bodily Fluids (free) AND Social Medicine: Twitter in Healthcare – Journal of Clinical Medicine (free) AND University of Twitter? Scientists give impromptu lecture critiquing nutrition research – CBC (free) AND Twitter-Based Medicine: How Social Media is Changing the Public’s View of Medicine – The Health Care Blog (free) AND What’s your doctor reading? How social media is disrupting medical education – National Post (free)
“From online journal clubs to ‘tweetorials’ to conference updates, social media is changing the dissemination and discussion of biomedicine.”
6 – BBC Investigation on the Reporting of the EXCEL Trial Raises Concerns Over the Safety of Stents for Left Main Disease in Patients at Low Risk for Surgery
Surgeons withdraw support for heart disease advice – BBC (free)
YouTube Video: European guidelines on heart disease under review – BBC Newsnight (free)
See also: EACTS responds to BBC Newsnight’s investigation on the EXCEL trial – European Association for Cardio-Thoracic Surgery (free)
Commentary: EACTS Pulls Out of Left Main Guidelines After BBC Bombshell Alleging EXCEL Trial Cover-up – TCTMD (free)
See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Source: NEJM Journal Watch
Related: Management of hyperkalemia in the acutely ill patient – Annals of Intensive Care (free) AND Acute Management of Hyperkalemia – Current Heart Failure Reports (free) AND Diagnosis and treatment of hyperkalemia – Cleveland Clinic Journal of Medicine (free) AND Potassium Disorders: Hypokalemia and Hyperkalemia – American Family Physician (free) AND Management of hyperkalemia in patients with kidney disease: a position paper endorsed by the Italian Society of Nephrology – Journal of Nephrology (free)
Source: Critical Care Reviews
9 – Does general anesthesia affect neurodevelopment in infants and children? – The BMJ (free for a limited period)
Related Study: Randomized Trial: General Anesthesia in Infancy Does Not Seem to Impair Neurodevelopmental Outcomes (link to abstract and commentary)


