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Perspective – A Reality Check on Artificial Intelligence: Are Health Care Claims Overblown?

8 Jan, 2020 | 01:09h | UTC

A Reality Check on Artificial Intelligence: Are Health Care Claims Overblown? – Kaiser Health News (free)

 


Editorial: The Harms of Promoting ‘Zero Harm’

8 Jan, 2020 | 01:07h | UTC

The harms of promoting ‘Zero Harm’ – BMJ Quality & Safety (free for a limited period) (via @brhospitalist)

Related Viewpoint: Managing risk in hazardous conditions: improvisation is not enough – BMJ Quality & Safety (free)

 


The Good, the Bad and the Ugly in Global Health in 2019

8 Jan, 2020 | 01:07h | UTC

The good, the bad and the ugly in global health in 2019 – CNN (free)

 


[Abstract Only] Randomized Trial: Direct Oral Anticoagulant Similarly Effective as Standard Anticoagulants for the Treatment of Acute Venous Thromboembolism in Children

8 Jan, 2020 | 01:02h | UTC

Rivaroxaban compared with standard anticoagulants for the treatment of acute venous thromboembolism in children: a randomised, controlled, phase 3 trial – The Lancet Haematology (link to abstract – $ for full-text)

Commentary: Thrombosis: Anticoagulant Rivaroxaban soon also available for children – Medical University of Vienna (free)

 


Perspective: What Is the Keto Diet and Does It Work?

8 Jan, 2020 | 00:59h | UTC

What Is the Keto Diet and Does It Work? – The New York Times (10 articles per month are free)

Related: The Ketogenic Diet: Pros and Cons (free articles on the subject)

 


Randomized Trial: Safety and Adverse Events after Targeted Lung Denervation for Symptomatic Moderate to Severe COPD

8 Jan, 2020 | 01:04h | UTC

Safety and Adverse Events after Targeted Lung Denervation for Symptomatic Moderate to Severe Chronic Obstructive Pulmonary Disease (AIRFLOW). A Multicenter Randomized Controlled Clinical Trial – American Journal of Respiratory and Critical Care Medicine (free)

 


Clinical Guideline Highlights for the Hospitalist: Diagnosis and Management of Measles

8 Jan, 2020 | 01:00h | UTC

Clinical Guideline Highlights for the Hospitalist: Diagnosis and Management of Measles – Journal of Hospital Medicine (free)

Original Guideline: Centers for Disease Control and Prevention. Measles (Rubeola): For Healthcare Professionals. 2019 (free)

 


Consensus Statement: Insufficient Evidence to Recommend Brain Health Supplements

8 Jan, 2020 | 00:57h | UTC

The Real Deal on Brain Health Supplements: GCBH Recommendations on Vitamins, Minerals, and Other Dietary Supplements – Global Council and Brain Health (free)

Commentary: AARP report: Insufficient evidence that dietary supplements benefit brain health – Science-Based Medicine (free)

 


Low Carbohydrate Diets for Diabetes: A Review of the Clinical Effectiveness and Guidelines

8 Jan, 2020 | 00:58h | UTC

Low Carbohydrate Diets for Diabetes: A Review of the Clinical Effectiveness and Guidelines – Canadian Agency for Drugs and Technologies in Health (free)

 


Meta-Analysis: Comparative Effects of 18 Antipsychotics on Metabolic Function in Patients with Schizophrenia

8 Jan, 2020 | 00:56h | UTC

Comparative effects of 18 antipsychotics on metabolic function in patients with schizophrenia, predictors of metabolic dysregulation, and association with psychopathology: a systematic review and network meta-analysis – The Lancet Psychiatry (free)

Commentaries: Insights into metabolic dysregulations associated with antipsychotics – The Lancet Psychiatry (free) AND Not all antipsychotics increase the risk of diabetes and raise cholesterol – some may be protective – The Conversation (free)

 


[Abstract Only] Study: Nonculprit-lesion PCI Timing in Patients With ST-Segment Elevation Myocardial Infarction

8 Jan, 2020 | 00:54h | UTC

Timing of Staged Nonculprit Artery Revascularization in Patients With ST-Segment Elevation Myocardial Infarction COMPLETE Trial – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: New COMPLETE Data Affirm Benefit of Nonculprit PCI in STEMI Regardless of Timing – TCTMD (free) AND Timing of Staged Nonculprit Artery Revascularization in Patients With ST-Segment Elevation Myocardial Infarction: COMPLETE Trial – F1000Prime (free)

Original Randomized Trial: #ESCCongress – Complete Revascularization Superior to Culprit-lesion-only PCI in Patients with ST-segment Elevation Myocardial Infarction (STEMI) and Multivessel Coronary Artery Disease – New England Journal of Medicine (link to abstract, commentaries and resources on the subject)

 


Cohort Study: Risk of Operative and Nonoperative Interventions After Roux-en-Y Gastric Bypass vs. Vertical Sleeve Gastrectomy

8 Jan, 2020 | 00:53h | UTC

Risk of Operative and Nonoperative Interventions Up to 4 Years After Roux-en-Y Gastric Bypass vs Vertical Sleeve Gastrectomy in a Nationwide US Commercial Insurance Claims Database – JAMA Network Open (free)

Commentaries: Comparing future risks associated with gastric bypass and gastric sleeve surgery – Harvard Pilgrim Health Care Institute (free) AND Study Shows Risks for Additional Procedures after Bariatric Surgery – Wake Forest Baptist Health (free)

 


[Abstract Only] Study: Long-term Follow Up of Gene Therapy for Hemophilia A

8 Jan, 2020 | 00:52h | UTC

Multiyear Follow-up of AAV5-hFVIII-SQ Gene Therapy for Hemophilia A – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Study shows safety, long-term beneficial impact of gene therapy for patients with Hemophilia A – Queen Mary University of London (free)

 


[Abstract Only] Randomized Trial: Tucatinib, Trastuzumab, and Capecitabine for HER2-Positive Metastatic Breast Cancer

8 Jan, 2020 | 00:51h | UTC

Tucatinib, Trastuzumab, and Capecitabine for HER2-Positive Metastatic Breast Cancer – New England Journal of Medicine (free)

Commentaries: SABCS 2019: Adding Tucatinib to Capecitabine/Trastuzumab Improved Survival for Patients With Advanced HER2-Positive Breast Cancer – The ASCO Post (free) AND HER2CLIMB and DESTINY-Breast01 Findings in Heavily Pretreated HER2-positive MBC – ESMO (free)

 


[Abstract Only] Randomized Trial: Overall Survival with Ribociclib plus Fulvestrant in Advanced Breast Cancer

8 Jan, 2020 | 00:51h | UTC

Overall Survival with Ribociclib plus Fulvestrant in Advanced Breast Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Targeted therapy drug helps women with aggressive breast cancer live longer – University of California (free) AND Overall Survival With the Addition of Ribociclib to Fulvestrant in Hormone Receptor–Positive, HER2-Negative Advanced Breast Cancer: MONALEESA-3 – The ASCO Post (free)

 


Tue January 07 – 10 Stories of The Day!

7 Jan, 2020 | 07:07h | UTC

 

1 – Gastrointestinal bleeding prophylaxis for critically ill patients: a clinical practice guideline – The BMJ (free)

See also: Efficacy and safety of gastrointestinal bleeding prophylaxis in critically ill patients: systematic review and network meta-analysis – The BMJ (free)

 

2 – European Society of Endocrinology Clinical Practice Guideline: Endocrine work-up in obesity – European Journal of Endocrinology (free)

 

3 – Homepage: Special Issue: Advances in Perioperative Care – BJS / Anaesthesia (free articles)

– Perioperative care and collaboration between surgeons and anaesthetists – it’s about time

– Role of the anaesthetist in postoperative care

– Framework for prehabilitation services

– Role of critical care in improving outcomes for high‐risk surgical patients

– Scoping review of mode of anaesthesia in emergency surgery

– Strategies to minimize intraoperative blood loss during major surgery

– Perioperative care of the obese patient

– Rational performance metrics for operating theatres, principles of efficiency, and how to achieve it

– Acute postoperative pain management

– Meta‐analysis of preoperative high‐sensitivity cardiac troponin measurement in non‐cardiac surgical patients at risk of cardiovascular complications

– Network meta‐analysis of urinary retention and mortality after Lichtenstein repair of inguinal hernia under local, regional or general anaesthesia

– Meta‐analysis of α‐blockade versus no blockade before adrenalectomy for phaeochromocytoma

– Network meta‐analysis of local and regional analgesia following colorectal resection

– Randomized clinical trial of intraoperative dexmedetomidine to prevent delirium in the elderly undergoing major non‐cardiac surgery

– Randomized clinical trial of continuous transversus abdominis plane block, epidural or patient‐controlled analgesia for patients undergoing laparoscopic colorectal cancer surgery

– Qualitative study of clinician and patient perspectives on the mode of anaesthesia for emergency surgery

– Variation in global uptake of the Surgical Safety Checklist

– Safety and efficacy of non‐steroidal anti‐inflammatory drugs to reduce ileus after colorectal surgery

– International multicentre review of perioperative management and outcome for catecholamine‐producing tumours

 

4 – National, regional, and global burdens of disease from 2000 to 2016 attributable to alcohol use: a comparative risk assessment study – The Lancet Public Health (free)

Commentary: The burden of alcohol use: better data and strong policies towards a sustainable development – The Lancet Public Health (free)

Related: Related: WHO Global Status Report on Alcohol and Health 2018 (free report and commentaries) AND Alcohol Use and Burden for 195 Countries and Territories – The Lancet (free study and commentaries) AND Prioritising action on alcohol for health and development – The BMJ (free)

 

5 – Critical Care Management of Toxicities Associated With Targeted Agents and Immunotherapies for Cancer – Critical Care Medicine (free)

Related: Immune Checkpoint Inhibitor Toxicities (free guidelines and reviews on the subject)

 

6 – Artificial Intelligence Is Rushing Into Patient Care – And Could Raise Risks – Scientific American (a few articles per month are free)

“AI systems are not as rigorously tested as other medical devices, and have already made serious mistakes.”

 

7 – Diagnosis and treatment of autoimmune hemolytic anemia in adults: Recommendations from the First International Consensus Meeting – Blood Reviews (free)

Related: Autoimmune hemolytic anemia – Hematology (free) AND Guidelines on the management of drug‐induced immune and secondary autoimmune, haemolytic anaemia – British Journal of Haematology (free)

 

8 – Efficacy of faecal microbiota transplantation for patients with irritable bowel syndrome in a randomised, double-blind, placebo-controlled study – Gut (free)

Related Articles: Faecal microbiota transplantation versus placebo for moderate-to-severe irritable bowel syndrome: a double-blind, randomised, placebo-controlled, parallel-group, single-centre trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text) AND The effect of fecal microbiota transplantation on IBS related quality of life and fatigue in moderate to severe non-constipated irritable bowel: Secondary endpoints of a double blind, randomized, placebo-controlled trial – EbioMedicine (free)

 

9 – Efficacy and Safety of Early vs Elective Colonoscopy for Acute Lower Gastrointestinal Bleeding – Gastroenterology (free)

Commentary: Colonoscopy for Lower Gastrointestinal Bleeding—Time Is Not of the Essence – Gastroenterology (free)

 

10 – Early Colonoscopy Does Not Improve Outcomes of Patients With Lower Gastrointestinal Bleeding: Systematic Review of Randomized Trials – Clinical Gastroenterology & Hepatology (link to abstract – $ for full-text)

Commentary: Early colonoscopy did not improve outcomes in those hospitalized for lower GI bleeding – ACP Gastroenterology (free)

 


Special Issue: Advances in Perioperative Care

7 Jan, 2020 | 01:50h | UTC

Homepage: Special Issue: Advances in Perioperative Care – BJS / Anaesthesia (free articles)

– Perioperative care and collaboration between surgeons and anaesthetists – it’s about time

– Role of the anaesthetist in postoperative care

– Framework for prehabilitation services

– Role of critical care in improving outcomes for high‐risk surgical patients

– Scoping review of mode of anaesthesia in emergency surgery

– Strategies to minimize intraoperative blood loss during major surgery

– Perioperative care of the obese patient

– Rational performance metrics for operating theatres, principles of efficiency, and how to achieve it

– Acute postoperative pain management

– Meta‐analysis of preoperative high‐sensitivity cardiac troponin measurement in non‐cardiac surgical patients at risk of cardiovascular complications

– Network meta‐analysis of urinary retention and mortality after Lichtenstein repair of inguinal hernia under local, regional or general anaesthesia

– Meta‐analysis of α‐blockade versus no blockade before adrenalectomy for phaeochromocytoma

– Network meta‐analysis of local and regional analgesia following colorectal resection

– Randomized clinical trial of intraoperative dexmedetomidine to prevent delirium in the elderly undergoing major non‐cardiac surgery

– Randomized clinical trial of continuous transversus abdominis plane block, epidural or patient‐controlled analgesia for patients undergoing laparoscopic colorectal cancer surgery

– Qualitative study of clinician and patient perspectives on the mode of anaesthesia for emergency surgery

– Variation in global uptake of the Surgical Safety Checklist

– Safety and efficacy of non‐steroidal anti‐inflammatory drugs to reduce ileus after colorectal surgery

– International multicentre review of perioperative management and outcome for catecholamine‐producing tumours

 

Related Commentary on Twitter

 


Guideline: Endocrine Work-up in Obesity

7 Jan, 2020 | 01:52h | UTC

European Society of Endocrinology Clinical Practice Guideline: Endocrine work-up in obesity – European Journal of Endocrinology (free)

 


The BMJ Guideline: Gastrointestinal Bleeding Prophylaxis for Critically Ill Patients

7 Jan, 2020 | 01:53h | UTC

Gastrointestinal bleeding prophylaxis for critically ill patients: a clinical practice guideline – The BMJ (free)

See also: Efficacy and safety of gastrointestinal bleeding prophylaxis in critically ill patients: systematic review and network meta-analysis – The BMJ (free)

 


Perspective: Artificial Intelligence Is Rushing into Patient Care – And Could Raise Risks

7 Jan, 2020 | 01:44h | UTC

Artificial Intelligence Is Rushing Into Patient Care – And Could Raise Risks – Scientific American (a few articles per month are free)

“AI systems are not as rigorously tested as other medical devices, and have already made serious mistakes.”

 


National, Regional, and Global Burdens of Disease Attributable to Alcohol Use

7 Jan, 2020 | 01:46h | UTC

National, regional, and global burdens of disease from 2000 to 2016 attributable to alcohol use: a comparative risk assessment study – The Lancet Public Health (free)

Commentary: The burden of alcohol use: better data and strong policies towards a sustainable development – The Lancet Public Health (free)

Related: Related: WHO Global Status Report on Alcohol and Health 2018 (free report and commentaries) AND Alcohol Use and Burden for 195 Countries and Territories – The Lancet (free study and commentaries) AND Prioritising action on alcohol for health and development – The BMJ (free)

 


Randomized Trial: Efficacy of Fecal Microbiota Transplantation for Patients with Irritable Bowel Syndrome

7 Jan, 2020 | 01:40h | UTC

Efficacy of faecal microbiota transplantation for patients with irritable bowel syndrome in a randomised, double-blind, placebo-controlled study – Gut (free)

Related Articles: Faecal microbiota transplantation versus placebo for moderate-to-severe irritable bowel syndrome: a double-blind, randomised, placebo-controlled, parallel-group, single-centre trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text) AND The effect of fecal microbiota transplantation on IBS related quality of life and fatigue in moderate to severe non-constipated irritable bowel: Secondary endpoints of a double blind, randomized, placebo-controlled trial – EbioMedicine (free)

 


Randomized Trial: Efficacy and Safety of Early vs. Elective Colonoscopy for Acute Lower Gastrointestinal Bleeding

7 Jan, 2020 | 01:38h | UTC

Efficacy and Safety of Early vs Elective Colonoscopy for Acute Lower Gastrointestinal Bleeding – Gastroenterology (free)

Commentary: Colonoscopy for Lower Gastrointestinal Bleeding—Time Is Not of the Essence – Gastroenterology (free)

 


Consensus: Diagnosis and Treatment of Autoimmune Hemolytic Anemia in Adults

7 Jan, 2020 | 01:41h | UTC

Diagnosis and treatment of autoimmune hemolytic anemia in adults: Recommendations from the First International Consensus Meeting – Blood Reviews (free)

Related: Autoimmune hemolytic anemia – Hematology (free) AND Guidelines on the management of drug‐induced immune and secondary autoimmune, haemolytic anaemia – British Journal of Haematology (free)

 


Critical Care Management of Toxicities Associated with Targeted Agents and Immunotherapies for Cancer

7 Jan, 2020 | 01:45h | UTC

Critical Care Management of Toxicities Associated With Targeted Agents and Immunotherapies for Cancer – Critical Care Medicine (free)

Related: Immune Checkpoint Inhibitor Toxicities (free guidelines and reviews on the subject)

 


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