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Study Commentary: ‘As-needed’ Combination Asthma Inhalers Can be More Effective than Regular Inhaled Steroids

9 Jan, 2020 | 23:12h | UTC

‘As-needed’ combination asthma inhalers can be more effective than regular inhaled steroids – NIHR Signal (free)

Original Study: Randomized Trial: In Adults with Mild to Moderate Asthma, As-Needed Long-acting Beta-agonist Plus an Inhaled Corticosteroid is as Effective as Maintenance Inhaled Corticosteroid Therapy Plus As-needed Short-acting Beta-agonist – The Lancet (link to abstract and commentary)

 


Study Commentary: Very Small Babies Appear not to be Affected by the Rate of Increasing Milk Feeds

9 Jan, 2020 | 23:18h | UTC

Very small babies appear not to be affected by the rate of increasing milk feeds – NIHR Signal (free)

Original Study: Controlled Trial of Two Incremental Milk-Feeding Rates in Preterm Infants – New England Journal of Medicine (link to abstract – $ for full-text)

 


Thu January 09 – 10 Stories of The Day!

9 Jan, 2020 | 09:34h | UTC

 

1 – Perforated and bleeding peptic ulcer: WSES guidelines – World Society of Emergency Surgery (free)

 

2 – 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee – Arthritis & Rheumatology (free)

News Release: ACR and Arthritis foundation release updated treatment guideline for OA – American College of Rheumatology (free)

 

3 – American Gastroenterological Association Clinical Practice Update: Management of Pancreatic Necrosis – Gastroenterology (free)

Related Reviews: Step-up approach for the management of pancreatic necrosis: a review of the literature – Trauma Surgery & Acute Care Open (free) AND Management of severe acute pancreatitis – The BMJ (free for a limited period)

Related Guidelines: 2019 WSES guidelines for the management of severe acute pancreatitis – World Journal of Emergency Surgery (free) AND American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis (free) AND Pancreatitis – National Institute for Health and Care Excellence (free) AND American College of Gastroenterology Guideline: Management of Acute Pancreatitis (free)

 

4 – Practices to Foster Physician Presence and Connection With Patients in the Clinical Encounter – JAMA (free for a limited period)

Editorials: Can an Evidence-Based Approach Improve the Patient-Physician Relationship? (free for a limited period) AND Connecting With Patients—The Missing Links (free for a limited period)

Author Interview: Practices to Foster Physician Presence and Connection with Patients in the Clinical Encounter (free)

Video: Connecting With Patients in Medicine (free)

 

5 – Health Care Hotspotting — A Randomized, Controlled Trial – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Reduce Health Costs By Nurturing The Sickest? A Much-Touted Idea Disappoints – Kaiser Health News (free) AND Did a high-profile program really slash hospital spending? Or was it a cautionary tale of ‘regression to the mean’? – STAT (free)

 

6 – Alex Nowbar’s weekly review, 8 January 2020 – The BMJ Opinion (free)

 

7 – Effectiveness of Virtual vs In-Person Inhaler Education for Hospitalized Patients With Obstructive Lung Disease: A Randomized Clinical Trial – JAMA Network Open (free)

Commentary: Virtual instruction for inhaler technique nearly as effective as in-person instruction, study finds – ACP Hospitalist (free)

 

8 – Beyond depression: Other uses for tricyclic antidepressants – Cleveland Clinic Journal of Medicine (free)

 

9 – Public-access defibrillation and neurological outcomes in patients with out-of-hospital cardiac arrest in Japan: a population-based cohort study – The Lancet (link to abstract – $ for full-text)

Related: The Effects of Public Access Defibrillation on Survival After Out-of-Hospital Cardiac Arrest: A Systematic Review of Observational Studies – Circulation (free) AND Bystander Efforts and 1-Year Outcomes in Out-of-Hospital Cardiac Arrest – New England Journal of Medicine (free) AND Impact of Bystander Automated External Defibrillator Use on Survival and Functional Outcomes in Shockable Observed Public Cardiac Arrests – Circulation (free)

 

10 – Expanding Heart Transplant in the Era of Direct-Acting Antiviral Therapy for Hepatitis C – JAMA Cardiology (link to abstract – $ for full-text)

Commentaries: Hepatitis C-positive donors a viable option to expand heart donor pool – Vanderbilt University Medical Center (free) AND Expanding heart transplant in the era of direct-acting antiviral therapy for hepatitis C – 2 Minute Medicine (free)

Related Studies: Transplant of Hepatitis C–Infected Kidneys Into Uninfected Recipients (link to abstract and commentaries) AND Heart and Lung Transplants from HCV-Infected Donors to Uninfected Recipients (link to abstract and commentaries) AND Direct-Acting Antiviral Prophylaxis in Kidney Transplantation From Hepatitis C Virus–Infected Donors to Noninfected Recipients (link to abstract and commentaries) AND Favorable 1-Year Outcomes with Transplantation of HCV-Viremic Kidneys (link to abstract and commentaries)

 


Study Commentary: Twenty MPH Speed Zones Reduce the Danger to Pedestrians and Cyclists

9 Jan, 2020 | 23:10h | UTC

Twenty mph speed zones reduce the danger to pedestrians and cyclists – NIHR Signal (free)

Original Study: Effects of 20 mph interventions on a range of public health outcomes: A meta-narrative evidence synthesis – Journal of Transport & Health (link to abstract – $ for full-text)

 


WSES Guideline: Perforated and Bleeding Peptic Ulcer

9 Jan, 2020 | 01:33h | UTC

Perforated and bleeding peptic ulcer: WSES guidelines – World Society of Emergency Surgery (free)

 


5 Practices to Foster Physician Presence and Connection with Patients in the Clinical Encounter

9 Jan, 2020 | 01:26h | UTC

Practices to Foster Physician Presence and Connection With Patients in the Clinical Encounter – JAMA (free for a limited period)

Editorials: Can an Evidence-Based Approach Improve the Patient-Physician Relationship? (free for a limited period) AND Connecting With Patients—The Missing Links (free for a limited period)

Author Interview: Practices to Foster Physician Presence and Connection with Patients in the Clinical Encounter (free)

Video: Connecting With Patients in Medicine (free)

 


AGA Clinical Practice Update: Management of Pancreatic Necrosis

9 Jan, 2020 | 01:27h | UTC

American Gastroenterological Association Clinical Practice Update: Management of Pancreatic Necrosis – Gastroenterology (free)

Related Reviews: Step-up approach for the management of pancreatic necrosis: a review of the literature – Trauma Surgery & Acute Care Open (free) AND Management of severe acute pancreatitis – The BMJ (free for a limited period)

Related Guidelines: 2019 WSES guidelines for the management of severe acute pancreatitis – World Journal of Emergency Surgery (free) AND American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis (free) AND Pancreatitis – National Institute for Health and Care Excellence (free) AND American College of Gastroenterology Guideline: Management of Acute Pancreatitis (free)

 


ACR Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee

9 Jan, 2020 | 01:29h | UTC

2019 American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee – Arthritis & Rheumatology (free)

News Release: ACR and Arthritis foundation release updated treatment guideline for OA – American College of Rheumatology (free)

 


Review – Beyond Depression: Other Uses for Tricyclic Antidepressants

9 Jan, 2020 | 01:21h | UTC

Beyond depression: Other uses for tricyclic antidepressants – Cleveland Clinic Journal of Medicine (free)

 


Alex Nowbar’s weekly review—8 January 2020

9 Jan, 2020 | 01:23h | UTC

Alex Nowbar’s weekly review, 8 January 2020 – The BMJ Opinion (free)

 


[Abstract Only] Health Care Hotspotting — A Randomized, Controlled Trial

9 Jan, 2020 | 01:24h | UTC

Health Care Hotspotting — A Randomized, Controlled Trial – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Reduce Health Costs By Nurturing The Sickest? A Much-Touted Idea Disappoints – Kaiser Health News (free) AND Did a high-profile program really slash hospital spending? Or was it a cautionary tale of ‘regression to the mean’? – STAT (free)

 


[Abstract Only] Study: Hepatitis C–positive Donors are a Viable Option for Heart Transplant

9 Jan, 2020 | 01:18h | UTC

Expanding Heart Transplant in the Era of Direct-Acting Antiviral Therapy for Hepatitis C – JAMA Cardiology (link to abstract – $ for full-text)

Commentaries: Hepatitis C-positive donors a viable option to expand heart donor pool – Vanderbilt University Medical Center (free) AND Expanding heart transplant in the era of direct-acting antiviral therapy for hepatitis C – 2 Minute Medicine (free)

Related Studies: Transplant of Hepatitis C–Infected Kidneys Into Uninfected Recipients (link to abstract and commentaries) AND Heart and Lung Transplants from HCV-Infected Donors to Uninfected Recipients (link to abstract and commentaries) AND Direct-Acting Antiviral Prophylaxis in Kidney Transplantation From Hepatitis C Virus–Infected Donors to Noninfected Recipients (link to abstract and commentaries) AND Favorable 1-Year Outcomes with Transplantation of HCV-Viremic Kidneys (link to abstract and commentaries)

 


Randomized Trial: Effectiveness of Virtual vs In-Person Inhaler Education for Hospitalized Patients With Obstructive Lung Disease

9 Jan, 2020 | 01:22h | UTC

Effectiveness of Virtual vs In-Person Inhaler Education for Hospitalized Patients With Obstructive Lung Disease: A Randomized Clinical Trial – JAMA Network Open (free)

Commentary: Virtual instruction for inhaler technique nearly as effective as in-person instruction, study finds – ACP Hospitalist (free)

 


AHA Science Advisory: Dietary Cholesterol and Cardiovascular Risk

8 Jan, 2020 | 22:23h | UTC

Dietary Cholesterol and Cardiovascular Risk: A Science Advisory from the American Heart Association – Circulation (free PDF)

Commentaries: Heart-healthy diets are naturally low in dietary cholesterol and can help to reduce the risk of heart disease and stroke – American Heart Association (free) AND AHA Recommends a Focus on Healthy Dietary Choices Over Cholesterol Cutoffs – Clinical Advisor (free) AND AHA Plugs ‘Dietary Patterns’ Over Dietary Cholesterol Targets – TCTMD (free)

 


[Abstract Only] Cohort Study: Public-access Defibrillation Linked to Better Neurological Outcomes in Patients with Out-of-hospital Cardiac Arrest

9 Jan, 2020 | 01:19h | UTC

Public-access defibrillation and neurological outcomes in patients with out-of-hospital cardiac arrest in Japan: a population-based cohort study – The Lancet (link to abstract – $ for full-text)

Related: The Effects of Public Access Defibrillation on Survival After Out-of-Hospital Cardiac Arrest: A Systematic Review of Observational Studies – Circulation (free) AND Bystander Efforts and 1-Year Outcomes in Out-of-Hospital Cardiac Arrest – New England Journal of Medicine (free) AND Impact of Bystander Automated External Defibrillator Use on Survival and Functional Outcomes in Shockable Observed Public Cardiac Arrests – Circulation (free)

 


[Abstract Only] Study: Sustained Weight Loss Linked to Lower Risk of Breast Cancer

8 Jan, 2020 | 22:20h | UTC

Sustained weight loss and risk of breast cancer in women ≥50 years: a pooled analysis of prospective data – JNCI: Journal of the National Cancer Institute (link to abstract – $ for full-text)

Commentaries: Large study links sustained weight loss to reduced breast cancer risk – American Cancer Society (free) AND Weight loss linked to lower chance of getting breast cancer for women over 50 – NHS Choices (free) AND Study Links Sustained Weight Loss to Reduced Breast Cancer Risk – The ASCO Post (free)

 


Opinion: Doctors, Nurses and the Paperwork Crisis That Could Unite Them

8 Jan, 2020 | 22:21h | UTC

Doctors, Nurses and the Paperwork Crisis That Could Unite Them – The New York Times (10 articles per month are free)

Related: Opinion – “The EMR has changed the doctor-patient duet into a ménage-à-trois” (free resources on the subject)

 


Randomized Trial: Effects of Alternate-day Fasting on Body Weight and Dyslipidemia in Patients with Non-alcoholic Fatty Liver Disease

8 Jan, 2020 | 22:19h | UTC

Effects of alternate-day fasting on body weight and dyslipidaemia in patients with non-alcoholic fatty liver disease: a randomised controlled trial – BMC Gastroenterology (free)

 


Consensus Report: Framing Opioid Prescribing Guidelines for Acute Pain

8 Jan, 2020 | 22:22h | UTC

Framing Opioid Prescribing Guidelines for Acute Pain – National Academies of Sciences, Engineering, and Medicine (free PDF)

Commentaries: Statement on National Academies of Sciences, Engineering, and Medicine report on framing opioid prescribing guidelines for acute pain – U.S Food & Drug Administration (free) AND National Academies outlines opioid guidelines, aiming to make approach to prescribing more consistent – STAT (free)

 


[Abstract Only] Randomized Trial: Olanzapine Plus Standard Antiemetic Therapy for the Prevention of Chemotherapy-induced Nausea and Vomiting

8 Jan, 2020 | 22:12h | UTC

Olanzapine 5 mg plus standard antiemetic therapy for the prevention of chemotherapy-induced nausea and vomiting (J-FORCE): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)

 

Related Commentary on Twitter

 


Can Risk be Predicted? An Umbrella Systematic Review of Current Risk Prediction Models for Cardiovascular Diseases, Diabetes and Hypertension

8 Jan, 2020 | 22:10h | UTC

Can risk be predicted? An umbrella systematic review of current risk prediction models for cardiovascular diseases, diabetes and hypertension – BMJ Open (free)

 


Systematic Review: Beta‐blockers for Suspected or Diagnosed Acute Myocardial Infarction

8 Jan, 2020 | 22:07h | UTC

Beta‐blockers for suspected or diagnosed acute myocardial infarction – Cochrane Library (free)

Summary: Beta-blockers versus placebo or no intervention for patients with suspected or diagnosed myocardial infarction – Cochrane Library (free)

 


Systematic Review: Selective Serotonin Reuptake Inhibitors (SSRIs) for Stroke Recovery

8 Jan, 2020 | 22:05h | UTC

Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery – Cochrane Library (free)

Summary: Selective Serotonin Reuptake Inhibitors for Stroke Recovery – Cochrane Library (free)

 


Systematic Review: Transcatheter Aortic Valve Implantation vs. Surgical Aortic Valve Replacement for Severe Aortic Stenosis in People with Low Surgical Risk

8 Jan, 2020 | 22:06h | UTC

Transcatheter aortic valve implantation versus surgical aortic valve replacement for severe aortic stenosis in people with low surgical risk – Cochrane Library (free)

Summary: Transcatheter aortic valve implantation versus surgical aortic valve replacement in people with severe aortic stenosis and low surgical risk (free)

“Long-term follow-up data are needed to further assess and validate these outcomes, especially durability, in the low surgical risk population.”

 


Diagnosing Fracture-Related Infection: Current Concepts and Recommendations

8 Jan, 2020 | 21:55h | UTC

Diagnosing Fracture-Related Infection: Current Concepts and Recommendations – Journal of Orthopaedic Trauma (free)

 


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