Archives
Study Commentary: ‘As-needed’ Combination Asthma Inhalers Can be More Effective than Regular Inhaled Steroids
9 Jan, 2020 | 23:12h | UTCOriginal Study: Randomized Trial: In Adults with Mild to Moderate Asthma, As-Needed Long-acting Beta-agonist Plus an Inhaled Corticosteroid is as Effective as Maintenance Inhaled Corticosteroid Therapy Plus As-needed Short-acting Beta-agonist – The Lancet (link to abstract and commentary)
Study Commentary: Very Small Babies Appear not to be Affected by the Rate of Increasing Milk Feeds
9 Jan, 2020 | 23:18h | UTCVery small babies appear not to be affected by the rate of increasing milk feeds – NIHR Signal (free)
Original Study: Controlled Trial of Two Incremental Milk-Feeding Rates in Preterm Infants – New England Journal of Medicine (link to abstract – $ for full-text)
Thu January 09 – 10 Stories of The Day!
9 Jan, 2020 | 09:34h | UTC
1 – Perforated and bleeding peptic ulcer: WSES guidelines – World Society of Emergency Surgery (free)
News Release: ACR and Arthritis foundation release updated treatment guideline for OA – American College of Rheumatology (free)
Related Reviews: Step-up approach for the management of pancreatic necrosis: a review of the literature – Trauma Surgery & Acute Care Open (free) AND Management of severe acute pancreatitis – The BMJ (free for a limited period)
Related Guidelines: 2019 WSES guidelines for the management of severe acute pancreatitis – World Journal of Emergency Surgery (free) AND American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis (free) AND Pancreatitis – National Institute for Health and Care Excellence (free) AND American College of Gastroenterology Guideline: Management of Acute Pancreatitis (free)
4 – Practices to Foster Physician Presence and Connection With Patients in the Clinical Encounter – JAMA (free for a limited period)
Editorials: Can an Evidence-Based Approach Improve the Patient-Physician Relationship? (free for a limited period) AND Connecting With Patients—The Missing Links (free for a limited period)
Author Interview: Practices to Foster Physician Presence and Connection with Patients in the Clinical Encounter (free)
Video: Connecting With Patients in Medicine (free)
5 – Health Care Hotspotting — A Randomized, Controlled Trial – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Reduce Health Costs By Nurturing The Sickest? A Much-Touted Idea Disappoints – Kaiser Health News (free) AND Did a high-profile program really slash hospital spending? Or was it a cautionary tale of ‘regression to the mean’? – STAT (free)
6 – Alex Nowbar’s weekly review, 8 January 2020 – The BMJ Opinion (free)
Commentary: Virtual instruction for inhaler technique nearly as effective as in-person instruction, study finds – ACP Hospitalist (free)
9 – Public-access defibrillation and neurological outcomes in patients with out-of-hospital cardiac arrest in Japan: a population-based cohort study – The Lancet (link to abstract – $ for full-text)
Related: The Effects of Public Access Defibrillation on Survival After Out-of-Hospital Cardiac Arrest: A Systematic Review of Observational Studies – Circulation (free) AND Bystander Efforts and 1-Year Outcomes in Out-of-Hospital Cardiac Arrest – New England Journal of Medicine (free) AND Impact of Bystander Automated External Defibrillator Use on Survival and Functional Outcomes in Shockable Observed Public Cardiac Arrests – Circulation (free)
10 – Expanding Heart Transplant in the Era of Direct-Acting Antiviral Therapy for Hepatitis C – JAMA Cardiology (link to abstract – $ for full-text)
Commentaries: Hepatitis C-positive donors a viable option to expand heart donor pool – Vanderbilt University Medical Center (free) AND Expanding heart transplant in the era of direct-acting antiviral therapy for hepatitis C – 2 Minute Medicine (free)
Related Studies: Transplant of Hepatitis C–Infected Kidneys Into Uninfected Recipients (link to abstract and commentaries) AND Heart and Lung Transplants from HCV-Infected Donors to Uninfected Recipients (link to abstract and commentaries) AND Direct-Acting Antiviral Prophylaxis in Kidney Transplantation From Hepatitis C Virus–Infected Donors to Noninfected Recipients (link to abstract and commentaries) AND Favorable 1-Year Outcomes with Transplantation of HCV-Viremic Kidneys (link to abstract and commentaries)
Study Commentary: Twenty MPH Speed Zones Reduce the Danger to Pedestrians and Cyclists
9 Jan, 2020 | 23:10h | UTCTwenty mph speed zones reduce the danger to pedestrians and cyclists – NIHR Signal (free)
Original Study: Effects of 20 mph interventions on a range of public health outcomes: A meta-narrative evidence synthesis – Journal of Transport & Health (link to abstract – $ for full-text)
WSES Guideline: Perforated and Bleeding Peptic Ulcer
9 Jan, 2020 | 01:33h | UTCPerforated and bleeding peptic ulcer: WSES guidelines – World Society of Emergency Surgery (free)
5 Practices to Foster Physician Presence and Connection with Patients in the Clinical Encounter
9 Jan, 2020 | 01:26h | UTCPractices to Foster Physician Presence and Connection With Patients in the Clinical Encounter – JAMA (free for a limited period)
Editorials: Can an Evidence-Based Approach Improve the Patient-Physician Relationship? (free for a limited period) AND Connecting With Patients—The Missing Links (free for a limited period)
Author Interview: Practices to Foster Physician Presence and Connection with Patients in the Clinical Encounter (free)
Video: Connecting With Patients in Medicine (free)
AGA Clinical Practice Update: Management of Pancreatic Necrosis
9 Jan, 2020 | 01:27h | UTCRelated Reviews: Step-up approach for the management of pancreatic necrosis: a review of the literature – Trauma Surgery & Acute Care Open (free) AND Management of severe acute pancreatitis – The BMJ (free for a limited period)
Related Guidelines: 2019 WSES guidelines for the management of severe acute pancreatitis – World Journal of Emergency Surgery (free) AND American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis (free) AND Pancreatitis – National Institute for Health and Care Excellence (free) AND American College of Gastroenterology Guideline: Management of Acute Pancreatitis (free)
ACR Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee
9 Jan, 2020 | 01:29h | UTCNews Release: ACR and Arthritis foundation release updated treatment guideline for OA – American College of Rheumatology (free)
Review – Beyond Depression: Other Uses for Tricyclic Antidepressants
9 Jan, 2020 | 01:21h | UTCBeyond depression: Other uses for tricyclic antidepressants – Cleveland Clinic Journal of Medicine (free)
Alex Nowbar’s weekly review—8 January 2020
9 Jan, 2020 | 01:23h | UTCAlex Nowbar’s weekly review, 8 January 2020 – The BMJ Opinion (free)
[Abstract Only] Health Care Hotspotting — A Randomized, Controlled Trial
9 Jan, 2020 | 01:24h | UTCHealth Care Hotspotting — A Randomized, Controlled Trial – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Reduce Health Costs By Nurturing The Sickest? A Much-Touted Idea Disappoints – Kaiser Health News (free) AND Did a high-profile program really slash hospital spending? Or was it a cautionary tale of ‘regression to the mean’? – STAT (free)
[Abstract Only] Study: Hepatitis C–positive Donors are a Viable Option for Heart Transplant
9 Jan, 2020 | 01:18h | UTCExpanding Heart Transplant in the Era of Direct-Acting Antiviral Therapy for Hepatitis C – JAMA Cardiology (link to abstract – $ for full-text)
Commentaries: Hepatitis C-positive donors a viable option to expand heart donor pool – Vanderbilt University Medical Center (free) AND Expanding heart transplant in the era of direct-acting antiviral therapy for hepatitis C – 2 Minute Medicine (free)
Related Studies: Transplant of Hepatitis C–Infected Kidneys Into Uninfected Recipients (link to abstract and commentaries) AND Heart and Lung Transplants from HCV-Infected Donors to Uninfected Recipients (link to abstract and commentaries) AND Direct-Acting Antiviral Prophylaxis in Kidney Transplantation From Hepatitis C Virus–Infected Donors to Noninfected Recipients (link to abstract and commentaries) AND Favorable 1-Year Outcomes with Transplantation of HCV-Viremic Kidneys (link to abstract and commentaries)
Randomized Trial: Effectiveness of Virtual vs In-Person Inhaler Education for Hospitalized Patients With Obstructive Lung Disease
9 Jan, 2020 | 01:22h | UTCCommentary: Virtual instruction for inhaler technique nearly as effective as in-person instruction, study finds – ACP Hospitalist (free)
AHA Science Advisory: Dietary Cholesterol and Cardiovascular Risk
8 Jan, 2020 | 22:23h | UTCCommentaries: Heart-healthy diets are naturally low in dietary cholesterol and can help to reduce the risk of heart disease and stroke – American Heart Association (free) AND AHA Recommends a Focus on Healthy Dietary Choices Over Cholesterol Cutoffs – Clinical Advisor (free) AND AHA Plugs ‘Dietary Patterns’ Over Dietary Cholesterol Targets – TCTMD (free)
[Abstract Only] Cohort Study: Public-access Defibrillation Linked to Better Neurological Outcomes in Patients with Out-of-hospital Cardiac Arrest
9 Jan, 2020 | 01:19h | UTCPublic-access defibrillation and neurological outcomes in patients with out-of-hospital cardiac arrest in Japan: a population-based cohort study – The Lancet (link to abstract – $ for full-text)
Related: The Effects of Public Access Defibrillation on Survival After Out-of-Hospital Cardiac Arrest: A Systematic Review of Observational Studies – Circulation (free) AND Bystander Efforts and 1-Year Outcomes in Out-of-Hospital Cardiac Arrest – New England Journal of Medicine (free) AND Impact of Bystander Automated External Defibrillator Use on Survival and Functional Outcomes in Shockable Observed Public Cardiac Arrests – Circulation (free)
[Abstract Only] Study: Sustained Weight Loss Linked to Lower Risk of Breast Cancer
8 Jan, 2020 | 22:20h | UTCSustained weight loss and risk of breast cancer in women ≥50 years: a pooled analysis of prospective data – JNCI: Journal of the National Cancer Institute (link to abstract – $ for full-text)
Commentaries: Large study links sustained weight loss to reduced breast cancer risk – American Cancer Society (free) AND Weight loss linked to lower chance of getting breast cancer for women over 50 – NHS Choices (free) AND Study Links Sustained Weight Loss to Reduced Breast Cancer Risk – The ASCO Post (free)
Opinion: Doctors, Nurses and the Paperwork Crisis That Could Unite Them
8 Jan, 2020 | 22:21h | UTCDoctors, Nurses and the Paperwork Crisis That Could Unite Them – The New York Times (10 articles per month are free)
Related: Opinion – “The EMR has changed the doctor-patient duet into a ménage-à-trois” (free resources on the subject)
Randomized Trial: Effects of Alternate-day Fasting on Body Weight and Dyslipidemia in Patients with Non-alcoholic Fatty Liver Disease
8 Jan, 2020 | 22:19h | UTC
Consensus Report: Framing Opioid Prescribing Guidelines for Acute Pain
8 Jan, 2020 | 22:22h | UTCCommentaries: Statement on National Academies of Sciences, Engineering, and Medicine report on framing opioid prescribing guidelines for acute pain – U.S Food & Drug Administration (free) AND National Academies outlines opioid guidelines, aiming to make approach to prescribing more consistent – STAT (free)
[Abstract Only] Randomized Trial: Olanzapine Plus Standard Antiemetic Therapy for the Prevention of Chemotherapy-induced Nausea and Vomiting
8 Jan, 2020 | 22:12h | UTCOlanzapine 5 mg plus standard antiemetic therapy for the prevention of chemotherapy-induced nausea and vomiting (J-FORCE): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)
Related Commentary on Twitter
in phase III trial, patients received anti-emetic combination plus placebo or 5 mg olanzapine (dose lower than standard to avoid somnolence); 5 mg dose was deemed effective https://t.co/urEz3AKFdA
— NatureRevClinOncol (@NatRevClinOncol) December 19, 2019
Can Risk be Predicted? An Umbrella Systematic Review of Current Risk Prediction Models for Cardiovascular Diseases, Diabetes and Hypertension
8 Jan, 2020 | 22:10h | UTC
Systematic Review: Beta‐blockers for Suspected or Diagnosed Acute Myocardial Infarction
8 Jan, 2020 | 22:07h | UTCBeta‐blockers for suspected or diagnosed acute myocardial infarction – Cochrane Library (free)
Summary: Beta-blockers versus placebo or no intervention for patients with suspected or diagnosed myocardial infarction – Cochrane Library (free)
Systematic Review: Selective Serotonin Reuptake Inhibitors (SSRIs) for Stroke Recovery
8 Jan, 2020 | 22:05h | UTCSelective serotonin reuptake inhibitors (SSRIs) for stroke recovery – Cochrane Library (free)
Summary: Selective Serotonin Reuptake Inhibitors for Stroke Recovery – Cochrane Library (free)
Systematic Review: Transcatheter Aortic Valve Implantation vs. Surgical Aortic Valve Replacement for Severe Aortic Stenosis in People with Low Surgical Risk
8 Jan, 2020 | 22:06h | UTCTranscatheter aortic valve implantation versus surgical aortic valve replacement for severe aortic stenosis in people with low surgical risk – Cochrane Library (free)
Summary: Transcatheter aortic valve implantation versus surgical aortic valve replacement in people with severe aortic stenosis and low surgical risk (free)
“Long-term follow-up data are needed to further assess and validate these outcomes, especially durability, in the low surgical risk population.”
Diagnosing Fracture-Related Infection: Current Concepts and Recommendations
8 Jan, 2020 | 21:55h | UTC


