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Randomized Trial: Continuous Transversus Abdominis Plane Block, Epidural or Patient‐controlled Analgesia for Patients Undergoing Laparoscopic Colorectal Cancer Surgery

14 Jan, 2020 | 00:19h | UTC

Randomized clinical trial of continuous transversus abdominis plane block, epidural or patient‐controlled analgesia for patients undergoing laparoscopic colorectal cancer surgery – British Journal of Surgery (free)

Expert Consensus on the Management of Brain Arteriovenous Malformations

14 Jan, 2020 | 00:24h | UTC

Expert Consensus on the Management of Brain Arteriovenous Malformations – Asian Journal of Neurosurgery (free)

Perspective: FDA and NIH Let Clinical Trial Sponsors Keep Results Secret and Break the Law

14 Jan, 2020 | 00:21h | UTC

FDA and NIH let clinical trial sponsors keep results secret and break the law – Science (a few articles per month are free)

Related Commentary on Twitter

Shameful lack, non-compliance of reporting of clinical trials by academic medical centershttps://t.co/dmbSeUNJur #openaccess @sciencemagazine by @cpiller
comparison with industry striking pic.twitter.com/5aXMIvjGvQ

— Eric Topol (@EricTopol) January 13, 2020

Systematic Review: Patient Safety in Inpatient Mental Health Settings

14 Jan, 2020 | 00:18h | UTC

Patient safety in inpatient mental health settings: a systematic review – BMJ Open (free)

Meta-Analysis: Tranexamic Acid in Hip Fracture Surgery

14 Jan, 2020 | 00:16h | UTC

Tranexamic acid in hip fracture surgery: A systematic review and meta-analysis – Journal of Orthopedic Surgery (free)

Opinion – Should Bed Up Head Elevated be the New Standard Position for Rapid Sequence Intubation in the ED?

14 Jan, 2020 | 00:17h | UTC

Should Bed Up Head Elevated (BUHE) be the New Standard Position for RSI in the ED? – RebelEM (free)

Original Study: Comparison of Macintosh Laryngoscopy in Bed-up-Head–Elevated Position With GlideScope Laryngoscopy: A Randomized, Controlled, Noninferiority Trial – Anesthesia & Analgesia (link to abstract – $ for full-text)

[Abstract Only] Randomized Trial: Metoprolol and Aspirin Reduce Surrogate Measures of Cardiovascular Risk in Bereavement

14 Jan, 2020 | 00:14h | UTC

The effect of METOPROLOL and aspirin on cardiovascular risk in bereavement: A randomized controlled trial – American Heart Journal (link to abstract – $ for full-text)

[Abstract Only] Randomized Trial: Adding Acetaminophen to Ibuprofen Does Not Improve Symptoms in Acute Low Back Pain

14 Jan, 2020 | 00:12h | UTC

Ibuprofen Plus Acetaminophen Versus Ibuprofen Alone for Acute Low Back Pain: An Emergency Department–based Randomized Study – Academic Emergency Medicine (link to abstract – $ for full-text)

Commentary: RCT – Ibuprofen + Acetaminophen for Low Back Pain – JournalFeed (free)

Related: Paracetamol for low back pain – Cochrane Library (free)

Review: New Oral Anti-Cancer Drugs and Medication Safety

14 Jan, 2020 | 00:11h | UTC

New Oral Anti-Cancer Drugs and Medication Safety – Deutsches Ärzteblatt international (free)

Pregnancy-related Cardiovascular risk Indicators: Primary Care Approach to Postpartum Management and Prevention of Future Disease

14 Jan, 2020 | 00:07h | UTC

Review: The Use of Medication in Pregnancy

14 Jan, 2020 | 00:09h | UTC

The Use of Medication in Pregnancy – Deutsches Ärzteblatt international (free)

Review: Brainstem Dysfunction in Critically Ill Patients

14 Jan, 2020 | 00:05h | UTC

Brainstem dysfunction in critically ill patients – Critical Care (free)

Yes, Size Does Matter! Sample Size Calculations for Randomized Trials

14 Jan, 2020 | 00:06h | UTC

Yes, size does matter! Sample size calculations for randomised trials – British Journal of Obstetrics and Gynaecology (free)

[Abstract Only] Randomized Trial: Luspatercept in Patients with Lower-Risk Myelodysplastic Syndromes

14 Jan, 2020 | 00:03h | UTC

Luspatercept in Patients with Lower-Risk Myelodysplastic Syndromes – New England Journal of Medicine (link to abstract – $ for full-text)

Study: One Cycle of Bleomycin/Etoposide/Cisplatin May Be as Effective as Two for Patients With Testicular Cancer

14 Jan, 2020 | 00:04h | UTC

One Cycle of Bleomycin/Etoposide/Cisplatin May Be as Effective as Two for Patients With Testicular Cancer – The ASCO Post (free)

Original Study: The 111 Study: A Single-arm, Phase 3 Trial Evaluating One Cycle of Bleomycin, Etoposide, and Cisplatin as Adjuvant Chemotherapy in High-risk, Stage 1 Nonseminomatous or Combined Germ Cell Tumours of the Testis – European Urology (free)

ACC/AHA Appropriate Use Criteria for Multimodality Imaging During the Follow-Up Care of Patients With Congenital Heart Disease

12 Jan, 2020 | 21:29h | UTC

ACC/AHA/ASE/HRS/ISACHD/SCAI/SCCT/SCMR/SOPE 2020 Appropriate Use Criteria for Multimodality Imaging During the Follow-Up Care of Patients With Congenital Heart Disease – Journal of the American College of Cardiology (free)

Commentaries: Appropriate Use Criteria for Imaging of Congenital Heart Disease Patients: Key Points – American College of Cardiology (free) AND New AUC for Cardiac Imaging Follow-up in Congenital Heart Disease – TCTMD (free)

Randomized Trial: A Head-to-head Comparison of the Efficacy and Safety of Ixekizumab and Adalimumab in Biological-naïve Patients with Active Psoriatic Arthritis

14 Jan, 2020 | 00:02h | UTC

A head-to-head comparison of the efficacy and safety of ixekizumab and adalimumab in biological-naïve patients with active psoriatic arthritis: 24-week results of a randomised, open-label, blinded-assessor trial – Annals of Rheumatic Diseases (free)

Commentary: We Have a Winner: Head-to-Head Study Compares Biologics for PsA – MedPage Today (free registration required)

Mon January 13 – 10 Stories of The Day!

13 Jan, 2020 | 00:01h | UTC

1 – ACC/AHA/ASE/HRS/ISACHD/SCAI/SCCT/SCMR/SOPE 2020 Appropriate Use Criteria for Multimodality Imaging During the Follow-Up Care of Patients With Congenital Heart Disease – Journal of the American College of Cardiology (free)

Commentaries: Appropriate Use Criteria for Imaging of Congenital Heart Disease Patients: Key Points – American College of Cardiology (free) AND New AUC for Cardiac Imaging Follow-up in Congenital Heart Disease – TCTMD (free)

2 – Association of Deceased Donor Acute Kidney Injury With Recipient Graft Survival – JAMA Network Open (free)

Commentaries: Less-than-perfect kidneys can be successfully used for transplants, study shows – Johns Hopkins Medicine (free) AND Less than perfect kidneys safe for transplant, study shows – UPI (free) AND Greater Use of Deceased Donor AKI Kidneys Urged – Renal & Urology News (free)

3 – Adverse events in adults with latent tuberculosis infection receiving daily rifampicin or isoniazid: post-hoc safety analysis of two randomised controlled trials – The Lancet Infectious Diseases (free registration required)

Commentaries: What is the best regimen to treat latent tuberculosis infection? – The Lancet Infectious Diseases (free) AND Four Months of Rifampicin May Be Best Option for Latent TB – Medscape / Reuters (free registration required)

4 – Homepage: Palliative Care – Medicine (free articles)

– Palliative care: introduction

– Pain control in palliative care

– Interventional management of pain in cancer and palliative care

– Nausea and vomiting in palliative care

– Constipation and malignant bowel obstruction in palliative care

– Breathlessness in advanced disease

– Psychiatric conditions in palliative medicine

– Emergencies in palliative care

– Palliative care in non-malignant disease

– Management of less common symptoms in palliative care

– Complications of systemic anti-cancer treatment

– Care in the last hours and days of life

– Advance care-planning and clinical decision-making

– Ethical principles in end-of-life care

5 – Homepage: Uncommon Severe Infections in the Intensive Care Unit – Clinical Microbiology and Infection (free articles)

– Improving care for the ICU patient with suspected infection: a multidisciplinary perspective

– Necrotizing skin and soft-tissue infections in the intensive care unit

– Management of infected pancreatic necrosis in the intensive care unit: a narrative review

– Mediastinitis in the intensive care unit patient: a narrative review

– When not to start antibiotics: avoiding antibiotic overuse in the intensive care unit

6 – Uterine Balloon Tamponade for the Treatment of Postpartum Hemorrhage: a Systematic Review and Meta-Analysis – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)

Commentaries: Technique is almost 86 percent effective in preventing maternal death from hemorrhaging – Massachusetts General Hospital (free) AND Uterine Balloon Tamponade for Postpartum Bleeding Seems Safe – Physician’s Briefing (free)

7 – Different strategies for pharmacological thromboprophylaxis for lower-limb immobilisation after injury: systematic review and economic evaluation – Health Technology Assessment (free)

Source: EvidenceAlerts

8 – How I set up positive end-expiratory pressure: evidence- and physiology-based! – Critical Care (free)

9 – Mechanical ventilation in patients with acute ischaemic stroke: from pathophysiology to clinical practice – Critical Care (free)

10 – Tea consumption and the risk of atherosclerotic cardiovascular disease and all-cause mortality: The China-PAR project – European Journal of Preventive Cardiology (free for a limited period)

Commentaries: Tea drinkers live longer – European Society of Cardiology (free) AND Habitual Green Tea Drinkers May Live Longer – MedicalResearch.com (free) AND Expert reaction to study looking at tea drinking, and health and longevity – Science Media Centre (free)

Special Issue: Practical Aspects of Palliative Care

12 Jan, 2020 | 21:25h | UTC

Homepage: Palliative Care – Medicine (free articles)

– Palliative care: introduction

– Pain control in palliative care

– Interventional management of pain in cancer and palliative care

– Nausea and vomiting in palliative care

– Constipation and malignant bowel obstruction in palliative care

– Breathlessness in advanced disease

– Psychiatric conditions in palliative medicine

– Emergencies in palliative care

– Palliative care in non-malignant disease

– Management of less common symptoms in palliative care

– Complications of systemic anti-cancer treatment

– Care in the last hours and days of life

– Advance care-planning and clinical decision-making

– Ethical principles in end-of-life care

Study: Less-than-perfect Kidneys from Donors with Acute Kidney Injury can be Used for Transplantation

12 Jan, 2020 | 21:27h | UTC

Association of Deceased Donor Acute Kidney Injury With Recipient Graft Survival – JAMA Network Open (free)

Commentaries: Less-than-perfect kidneys can be successfully used for transplants, study shows – Johns Hopkins Medicine (free) AND Less than perfect kidneys safe for transplant, study shows – UPI (free) AND Greater Use of Deceased Donor AKI Kidneys Urged – Renal & Urology News (free)

Study: Rifampicin is Likely to be the Safest Latent Tuberculosis Infection Treatment Option

12 Jan, 2020 | 21:26h | UTC

Adverse events in adults with latent tuberculosis infection receiving daily rifampicin or isoniazid: post-hoc safety analysis of two randomised controlled trials – The Lancet Infectious Diseases (free registration required)

Commentaries: What is the best regimen to treat latent tuberculosis infection? – The Lancet Infectious Diseases (free) AND Four Months of Rifampicin May Be Best Option for Latent TB – Medscape / Reuters (free registration required)

Related Commentary on Twitter

New study ⁦@McGill_TB⁩: “In patients without a contraindication, rifampicin is likely to be the safest latent tuberculosis infection treatment option.” https://t.co/rg2wmcLcqo

— Madhu Pai, MD, PhD (@paimadhu) January 9, 2020