Archives
Alex Nowbar’s weekly research review—17 January 2020
21 Jan, 2020 | 02:59h | UTCAlex Nowbar’s weekly research review, 17 January 2020 – BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.
Practical Guidelines for the Treatment of Patellar Fractures in Adults
21 Jan, 2020 | 01:33h | UTCPractical guidelines for the treatment of patellar fractures in adults – Swiss Medical Weekly (free)
ASTRO Guideline: Definitive and Postoperative Radiation Therapy for Basal and Squamous Cell Cancers of the Skin
21 Jan, 2020 | 01:35h | UTCCommentary: ASTRO Issues Clinical Guideline on Radiation Therapy for Basal Cell and Cutaneous Squamous Cell Carcinomas – The ASCO Post (free)
Perspective: Is Defending Science-Based Medicine Worth It?
21 Jan, 2020 | 01:31h | UTCIs defending science-based medicine worth it? – Science-Based Medicine (free)
Guidelines for the Management of Retinal Vein Occlusion
21 Jan, 2020 | 01:32h | UTC
Cohort Study: Premature Menopause Linked to Increased Risk of Development of Chronic Conditions and Multimorbidity
21 Jan, 2020 | 01:30h | UTCCommentary: Premature menopause increases the risk of multiple health problems in your 60s – European Society of Human Reproduction and Embryology (free)
Onco-cardiology: Drug-drug Interactions of Antineoplastic and Cardiovascular Drugs
21 Jan, 2020 | 01:27h | UTC
The Health of Adolescents in Detention: A Global Scoping Review
21 Jan, 2020 | 01:28h | UTCThe health of adolescents in detention: a global scoping review – The Lancet Public Health (free)
Cohort Study: Association Between Physical Activity and Risk of Incident Arrhythmias
21 Jan, 2020 | 01:24h | UTC
[Abstract Only] Meta-Analysis: Thrombolysis for Acute Ischemic Stroke in the Unwitnessed or Extended Therapeutic Time Window
21 Jan, 2020 | 01:15h | UTCThrombolysis for acute ischemic stroke in the unwitnessed or extended therapeutic time window – Neurology (link to abstract – $ for full-text)
Source: EvidenceAlerts
Systematic Review: Metformin for Ovulation Induction in Women with a Diagnosis of Polycystic Ovary Syndrome and Subfertility
21 Jan, 2020 | 01:21h | UTCMetformin for ovulation induction (excluding gonadotrophins) in women with polycystic ovary syndrome – Cochrane Library (free)
Summary: Metformin for ovulation induction in women with a diagnosis of polycystic ovary syndrome and subfertility – Cochrane Library (free)
Related Commentary on Twitter
Just published! In #women with #PCOS, #metformin may increase live birth rates but probably increases gastrointestinal side effects compared to #placebo. We are uncertain if metformin plus CC improves live birth compared to CC alone#Cochrane #blogshot https://t.co/4PRR4YHOvM pic.twitter.com/pj2ZqCinxi
— Cochrane Gynaecology & Fertility (@CochraneCGF) December 17, 2019
Update on the Management of Inflammatory Bowel Disease During Pregnancy and Breastfeeding
21 Jan, 2020 | 01:17h | UTC
Systematic Review: Impact of Health Outcomes from Food Fortification with Multiple Micronutrients
21 Jan, 2020 | 01:19h | UTCFood fortification with multiple micronutrients: impact on health outcomes in general population – Cochrane Library (free)
Summary: Impact of food fortification with multiple micronutrients on health – Cochrane Library (free)
Clinical Management of Seafood Allergy
21 Jan, 2020 | 01:11h | UTCClinical Management of Seafood Allergy – The Journal of Allergy and Clinical Immunology: In Practice (free)
Meta-analysis: Stage-Specific Sensitivity of Fecal Immunochemical Tests for Detecting Colorectal Cancer
21 Jan, 2020 | 01:13h | UTCSource: EvidenceAlerts
Meta-Analysis of Randomized Trials: Effects of Metformin on Blood Lipid Profiles in Nondiabetic Adults
21 Jan, 2020 | 01:09h | UTC
Recommendations for Therapeutic Apheresis
21 Jan, 2020 | 01:10h | UTC
[Abstract Only] Randomized Trial: Satralizumab for Neuromyelitis Optica Spectrum Disorder
21 Jan, 2020 | 01:05h | UTCTrial of Satralizumab in Neuromyelitis Optica Spectrum Disorder – New England Journal of Medicine (link to abstract – $ for full-text)
Review: New‐onset Postoperative Atrial Fibrillation After Heart Surgery
21 Jan, 2020 | 01:04h | UTCRelated: Society of Cardiovascular Anesthesiologists/European Association of Cardiothoracic Anaesthetists Practice Advisory for the Management of Perioperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery – Anesthesia & Analgesia (free) AND New-Onset Atrial Fibrillation in Adult Patients After Cardiac Surgery – Current Anesthesiology Reports (free)
Randomized Trial: Electrocatheter-mediated High-voltage Pulsed Radiofrequency of the Dorsal Root Ganglion in the Treatment of Chronic Lumbosacral Neuropathic Pain
21 Jan, 2020 | 01:07h | UTCSource: EvidenceAlerts
WHO Report: Lack of New Antibiotics Threatens Global Efforts to Contain Drug-resistant Infections
19 Jan, 2020 | 21:46h | UTCSee Reports: Antibacterial agents in clinical development – an analysis of the antibacterial clinical development pipeline – World Health Organization (free PDF) AND Antibacterial agents in preclinical development – World Health Organization (free PDF)
Commentary: W.H.O. Warns That Pipeline for New Antibiotics Is Running Dry – The New York Times (10 articles per month are free)
Meta-Analysis: Prophylactic Intra-Abdominal Drainage Following Colorectal Anastomoses
21 Jan, 2020 | 01:02h | UTC
AGA Clinical Practice Guidelines on the Management of Moderate to Severe Ulcerative Colitis
19 Jan, 2020 | 21:47h | UTCRelated: British Society of Gastroenterology Guidelines on the Management of Inflammatory Bowel Disease (guidelines on the subject)
Mon January 20 – 10 Stories of The Day!
20 Jan, 2020 | 00:44h | UTC
Related: British Society of Gastroenterology Guidelines on the Management of Inflammatory Bowel Disease (guidelines on the subject)
See Reports: Antibacterial agents in clinical development – an analysis of the antibacterial clinical development pipeline – World Health Organization (free PDF) AND Antibacterial agents in preclinical development – World Health Organization (free PDF)
Commentary: W.H.O. Warns That Pipeline for New Antibiotics Is Running Dry – The New York Times (10 articles per month are free)
4 – Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Lack of Benefit of High-Dose Vitamin C, Thiamine, and Hydrocortisone Combination for Patients With Sepsis (free)
Conference Presentation: Effect of Vitamin C and Thiamine on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock (free)
Commentaries: JC: The Vitamins trial. Hydrocortisone, Vit C and Thiamine (Marik protocol – or not?) in sepsis – St Emlyn’s (free) AND Vitamin Treatment For Sepsis Fails In Large Trial – NPR (free) AND Metabolic Resuscitation: Was the answer inside us all along? – PulmCrit (free)
Editorial: Proton Pump Inhibitors vs Histamine-2 Receptor Blockers for Stress Ulcer Prophylaxis in Critically Ill Patients: Issues of Interpretability in Pragmatic Trials (free for a limited period)
Conference Presentation: Effect of Stress Ulcer Prophylaxis With PPIs vs H2RBs on Mortality in Ventilated ICU Patients (free)
Commentaries: JC: The PEPTIC study PPI vs H2RBs on the ICU – St Emlyn’s (free) AND Risks And Benefits Of Proton Pump Inhibitors To Prevent Gi Bleeds In Intensive Care Patients – MedicalResearch.com (free)
6 – A review of cancer immunotherapy toxicity – CA: A Cancer Journal for Clinicians (free)
Related: Immune Checkpoint Inhibitor Toxicities (free guidelines and reviews on the subject)
7 – New Chinese virus ‘will have infected hundreds’ – BBC (free)
Original Analysis: Estimating the potential total number of novel Coronavirus cases in Wuhan City, China – Imperial College London (free)
See also: As Thailand notes 2nd nCoV case, CDC begins airport screening – CIDRAP (free) AND China reports new virus cases, raising concern globally before key holiday – Reuters (free) AND China to step up countermeasures as virus outbreak grows – Reuters (free) AND China Reports New Cases of Deadly Virus, Adding to Fears of Outbreak – The New York Times (10 articles per month are free)
Related: CDC: Vaping Lung Illness Probably Caused by Vitamin E Acetate (free resources)
Original Article: 3 versus 6 months of adjuvant oxaliplatin-fluoropyrimidine combination therapy for colorectal cancer (SCOT): an international, randomised, phase 3, non-inferiority trial – The Lancet Oncology (free)
Source: EvidenceAlerts
10 – Femtosecond laser-assisted versus phacoemulsification cataract surgery (FEMCAT): a multicentre participant-masked randomised superiority and cost-effectiveness trial – The Lancet (link to abstract – $ for full-text)
ESC Position Paper: Peripartum Management of Hypertension
19 Jan, 2020 | 21:51h | UTC