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Cohort Study: Proton Pump Inhibitors Linked to Small Increased Risk of Fracture in Children

18 Mar, 2020 | 09:46h | UTC

Association Between Proton Pump Inhibitor Use and Risk of Fracture in Children – JAMA Pediatrics (free for a limited period)

Commentary: Proton-Pump Inhibitors: Small Increased Risk of Fractures in Children – MedicalResearch.com (free)

 


[Abstract Only] Study: Machine Learning for Early Prediction of Circulatory Failure in the Intensive Care Unit

18 Mar, 2020 | 09:43h | UTC

Early prediction of circulatory failure in the intensive care unit using machine learning – Nature Medicine (link to abstract – $ for full-text)

Commentary: Circulatory failure is predictable – ETH Zurich (free)

 


Radiology Department Preparedness for COVID-19: Radiology Scientific Expert Panel

17 Mar, 2020 | 08:47h | UTC

Radiology Department Preparedness for COVID-19: Radiology Scientific Expert Panel – Radiology (free)

Commentary: Experts stress radiology preparedness for COVID-19 – Radiology Society of North America (free)

 


Study: Using Artificial Intelligence to Analyze CT Scans may Better Predict Cardiovascular Risk than Established Clinical Parameters

18 Mar, 2020 | 09:45h | UTC

Automated CT biomarkers for opportunistic prediction of future cardiovascular events and mortality in an asymptomatic screening population: a retrospective cohort study – The Lancet Digital Health (free)

Commentaries: Artificial intelligence-derived imaging biomarkers to improve population health – The Lancet Digital Health (free) AND Artificial Intelligence Predicts Heart Disease Risk from CT Scans – NIH Research Matters (free)

 


Tue March 17 – 10 Stories of The Day!

17 Mar, 2020 | 08:55h | UTC

 

1 – Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV2) – Science (free)

Commentaries: 80% of COVID-19 spreads from people who don’t know they are sick – UPI (free) AND Coronavirus Is Hiding in Plain Sight – The New York Times (10 articles per month are free)

Related: COVID-19: Who Is Infectious? – Forbes (free) AND Infected people without symptoms might be driving the spread of coronavirus more than we realized – CNN (free)

 

2 – ‘A ticking time bomb’: Scientists worry about coronavirus spread in Africa – Science (free)

Related: Managing COVID-19 in Low- and Middle-Income Countries – JAMA (free) AND Inside the Efforts to Prepare African Countries for COVID-19 – TIME (free) AND Looming threat of COVID-19 infection in Africa: act collectively, and fast – The Lancet (free) AND Is the Africa prepared for tackling the COVID-19 (SARS-CoV-2) epidemic? – lessons from past outbreaks, ongoing pan-African public health efforts, and implications for the future – International Journal of Infectious Diseases (free PDF)

 

3 – Radiology Department Preparedness for COVID-19: Radiology Scientific Expert Panel – Radiology (free)

Commentary: Experts stress radiology preparedness for COVID-19 – Radiology Society of North America (free)

 

4 – Epidemiological Characteristics of 2143 Pediatric Patients With 2019 Coronavirus Disease in China – Pediatrics (free PDF)

Commentary: Children with COVID-19 Impacted Less Severely Than Adults: Study – American Academy of Pediatrics (free)

 

5 – Antibiotic Use and Outcomes in Children in the Emergency Department with Suspected Pneumonia – Pediatrics (free)

Commentary: Study questions role of antibiotics in kids’ pneumonia – CIDRAP (free)

 

6 – Dual Versus Triple Therapy for Atrial Fibrillation After Percutaneous Coronary Intervention: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Dual therapy for afib after PCI may reduce bleeding risk better than triple therapy – ACP Internist (free) AND Dual therapy reduces risk for bleeding better than triple therapy for patients with atrial fibrillation – American College of Physicians (free)

Related Meta-Analysis: Dual vs. Triple Antithrombotic Therapy in Patients with Atrial Fibrillation following PCI – European Heart Journal (free) AND Meta-analysis comparing double versus Triple Anti-thrombotic Therapy in Patients with Atrial Fibrillation and Coronary Artery Disease – The American Journal of Cardiology (free)

 

7 – #199 NephMadness: Hyperkalemia, Diet, K+ Binders, Exercise – The Curbsiders Internal Medicine Podcast (free)

See also: Episode List

 

8 – Tinnitus – JAMA (free for a limited period)

Related Guideline: Tinnitus: assessment and management – National Institute for Health and Care Excellence (free)

 

9 – Development and Validation of a Penicillin Allergy Clinical Decision Rule – JAMA Internal Medicine (free for a limited period)

 

10 – Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 17 March 2020 Edition

17 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

 


Epidemiological Characteristics of 2143 Pediatric Patients With 2019 Coronavirus Disease in China

17 Mar, 2020 | 08:45h | UTC

Epidemiological Characteristics of 2143 Pediatric Patients With 2019 Coronavirus Disease in China – Pediatrics (free PDF)

Commentary: Children with COVID-19 Impacted Less Severely Than Adults: Study – American Academy of Pediatrics (free)

 


‘A Ticking Time Bomb’: Scientists Worry About Coronavirus Spread in Africa

17 Mar, 2020 | 08:48h | UTC

‘A ticking time bomb’: Scientists worry about coronavirus spread in Africa – Science (free)

Related: Managing COVID-19 in Low- and Middle-Income Countries – JAMA (free) AND Inside the Efforts to Prepare African Countries for COVID-19 – TIME (free) AND Looming threat of COVID-19 infection in Africa: act collectively, and fast – The Lancet (free) AND Is the Africa prepared for tackling the COVID-19 (SARS-CoV-2) epidemic? – lessons from past outbreaks, ongoing pan-African public health efforts, and implications for the future – International Journal of Infectious Diseases (free PDF)

 


Podcast: Hyperkalemia, Diet, K+ Binders, Exercise

17 Mar, 2020 | 08:40h | UTC

#199 NephMadness: Hyperkalemia, Diet, K+ Binders, Exercise – The Curbsiders Internal Medicine Podcast (free)

See also: Episode List

 


COVID-19: Undocumented Infections are the Infection Source for 79% of Documented Cases

17 Mar, 2020 | 08:51h | UTC

Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV2) – Science (free)

Commentaries: 80% of COVID-19 spreads from people who don’t know they are sick – UPI (free) AND Coronavirus Is Hiding in Plain Sight – The New York Times (10 articles per month are free)

Related: COVID-19: Who Is Infectious? – Forbes (free) AND Infected people without symptoms might be driving the spread of coronavirus more than we realized – CNN (free)

 


[Abstract Only] Meta-Analysis: Dual Versus Triple Therapy for Atrial Fibrillation After Percutaneous Coronary Intervention

17 Mar, 2020 | 08:41h | UTC

Dual Versus Triple Therapy for Atrial Fibrillation After Percutaneous Coronary Intervention: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Dual therapy for afib after PCI may reduce bleeding risk better than triple therapy – ACP Internist (free) AND Dual therapy reduces risk for bleeding better than triple therapy for patients with atrial fibrillation – American College of Physicians (free)

Related Meta-Analysis: Dual vs. Triple Antithrombotic Therapy in Patients with Atrial Fibrillation following PCI – European Heart Journal (free) AND Meta-analysis comparing double versus Triple Anti-thrombotic Therapy in Patients with Atrial Fibrillation and Coronary Artery Disease – The American Journal of Cardiology (free)

 


Clinical Update: Tinnitus

17 Mar, 2020 | 08:38h | UTC

Tinnitus – JAMA (free for a limited period)

Related Guideline: Tinnitus: assessment and management – National Institute for Health and Care Excellence (free)

 


Observational Study Suggests Antibiotic Use Does Not Improve Outcomes in Children in the Emergency Department with Suspected Pneumonia

17 Mar, 2020 | 08:43h | UTC

Antibiotic Use and Outcomes in Children in the Emergency Department with Suspected Pneumonia – Pediatrics (free)

Commentary: Study questions role of antibiotics in kids’ pneumonia – CIDRAP (free)

 


Study: Development and Validation of a Penicillin Allergy Clinical Decision Rule

17 Mar, 2020 | 08:37h | UTC

Development and Validation of a Penicillin Allergy Clinical Decision Rule – JAMA Internal Medicine (free for a limited period)

 


Interim Guidance: Clinical Management of Severe Acute Respiratory Infection When Novel Coronavirus (nCoV) Infection is Suspected

16 Mar, 2020 | 08:01h | UTC

Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected – World Health Organization (free PDF)

Related: Severe SARS-CoV-2 Infections: Practical Considerations and Management Strategy for Intensivists (free studies and reviews)

 

Related Commentary on Twitter

 


Mon March 16 – 10 Stories of The Day!

16 Mar, 2020 | 08:04h | UTC

 

1 – Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected – World Health Organization (free PDF)

Related: Severe SARS-CoV-2 Infections: Practical Considerations and Management Strategy for Intensivists (free studies and reviews)

 

2 – Mental Health and Psychosocial Considerations During COVID-19 Outbreak – World Health Organization (free PDF)

Related: The psychological impact of quarantine and how to reduce it: rapid review of the evidence – The Lancet (free) AND Behavioural scientists form new front in battle against coronavirus – The Guardian (free)

“Minimize watching, reading or listening to news that causes you to feel anxious or distressed; seek information only from trusted sources and mainly to take practical steps to prepare your plans and protect yourself and loved ones.”

 

3 – Critical Care Utilization for the COVID-19 Outbreak in Lombardy, Italy: Early Experience and Forecast During an Emergency Response – JAMA (free)

Related Video: Coronavirus in Italy – Report From The Front Lines – JAMA (free)

 

4 – Coronavirus Infections in Children Including COVID-19: An Overview of the Epidemiology, Clinical Features, Diagnosis, Treatment and Prevention Options in Children – The Pediatric Infectious Diseases Journal (free PDF)

Commentary: COVID-19 appears less severe in children – Wolters Kluwer Health (free)

Related: A Review of Coronavirus Disease-2019 (COVID-19) – Indian Journal of Pediatrics (free) AND Detection of Covid-19 in Children in Early January 2020 in Wuhan, China – New England Journal of Medicine (free) AND Coronavirus with a baby: what you need to know to prepare and respond – The Conversation (free)

 

5 – Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding – Nature Medicine (free)

Commentaries: How Does The Coronavirus Affect Kids? What We Know So Far About COVID-19 In Children – Forbes (free) AND Coronavirus study finds children with COVID-19 show milder symptom pattern – Reuters (free)

“Children infected with the #COVID19 outbreak coronavirus, SARS-CoV-2, show mild symptoms but prolonged shedding of viral RNA in feces, suggesting that the fecal–oral route might play a role in virus transmission #CORONAVIRUS” (via @NatureMedicine see Tweet)

 

6 – COVID-19 Airway Management Principles – Intensive Care Society; The Faculty of Intensive Care Management; Association of Anaesthetists; and Royal College of Anaesthetists (free)

Summary: COVID-19 Airway management principles (free PDF)

 

7 – When Guidelines Recommend Shared Decision-making – JAMA (free)

Author Interview: When Guidelines Recommend Shared Decision-making (free audio)

 

8 – Association of Functional, Cognitive, and Psychological Measures With 1-Year Mortality in Patients Undergoing Major Surgery – JAMA Surgery (free for a limited period)

 

9 – The Palliative Care of Patients with Incurable Cancer – Deutsches Ärzteblatt international (free)

 

10 – Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 16 March 2020 Edition

16 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

 


Critical Care Utilization for the COVID-19 Outbreak in Lombardy, Italy: Early Experience and Forecast During an Emergency Response

16 Mar, 2020 | 07:55h | UTC

Critical Care Utilization for the COVID-19 Outbreak in Lombardy, Italy: Early Experience and Forecast During an Emergency Response – JAMA (free)

Related Video: Coronavirus in Italy – Report From The Front Lines – JAMA (free)

 


Study: Characteristics of Pediatric SARS-CoV-2 Infection and Potential Evidence for Persistent Fecal Viral Shedding

16 Mar, 2020 | 07:50h | UTC

Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding – Nature Medicine (free)

Commentaries: How Does The Coronavirus Affect Kids? What We Know So Far About COVID-19 In Children – Forbes (free) AND Coronavirus study finds children with COVID-19 show milder symptom pattern – Reuters (free)

“Children infected with the #COVID19 outbreak coronavirus, SARS-CoV-2, show mild symptoms but prolonged shedding of viral RNA in feces, suggesting that the fecal–oral route might play a role in virus transmission #CORONAVIRUS” (via @NatureMedicine see Tweet)

 


WHO Guidance: Mental Health and Psychosocial Considerations During COVID-19 Outbreak

16 Mar, 2020 | 07:57h | UTC

Mental Health and Psychosocial Considerations During COVID-19 Outbreak – World Health Organization (free PDF)

Related: The psychological impact of quarantine and how to reduce it: rapid review of the evidence – The Lancet (free) AND Behavioural scientists form new front in battle against coronavirus – The Guardian (free)

“Minimize watching, reading or listening to news that causes you to feel anxious or distressed; seek information only from trusted sources and mainly to take practical steps to prepare your plans and protect yourself and loved ones.”

 


Review: Coronavirus Infections in Children Including COVID-19

16 Mar, 2020 | 07:52h | UTC

Coronavirus Infections in Children Including COVID-19: An Overview of the Epidemiology, Clinical Features, Diagnosis, Treatment and Prevention Options in Children – The Pediatric Infectious Diseases Journal (free PDF)

Commentary: COVID-19 appears less severe in children – Wolters Kluwer Health (free)

Related: A Review of Coronavirus Disease-2019 (COVID-19) – Indian Journal of Pediatrics (free) AND Detection of Covid-19 in Children in Early January 2020 in Wuhan, China – New England Journal of Medicine (free) AND Coronavirus with a baby: what you need to know to prepare and respond – The Conversation (free)

 


Guidance: COVID-19 Airway Management Principles

16 Mar, 2020 | 07:47h | UTC

COVID-19 Airway Management Principles – Intensive Care Society; The Faculty of Intensive Care Management; Association of Anaesthetists; and Royal College of Anaesthetists (free)

Summary: COVID-19 Airway management principles (free PDF)

 


Cohort Study: Association of Functional, Cognitive, and Psychological Measures With 1-Year Mortality in Patients Undergoing Major Surgery

16 Mar, 2020 | 07:43h | UTC

Association of Functional, Cognitive, and Psychological Measures With 1-Year Mortality in Patients Undergoing Major Surgery – JAMA Surgery (free for a limited period)

 


Fri March 13 – 10 Stories of The Day!

13 Mar, 2020 | 08:04h | UTC

 

 

1 – The SIFIPAC/WSES/SICG/SIMEU guidelines for diagnosis and treatment of acute appendicitis in the elderly (2019 edition) – World Journal of Emergency Surgery (free)

 

2 – Canadian Cardiovascular Society/Canadian Cardiac Transplant Network Position Statement on Heart Transplantation: Patient Eligibility, Selection, and Post-Transplantation Care – Canadian Journal of Cardiology (free for a limited period)

 

3 – Canadian Cardiovascular Society/Canadian Heart Failure Society Joint Position Statement on the Evaluation and Management of Patients With Cardiac Amyloidosis – Canadian Journal of Cardiology (free for a limited period)

 

4 – 5 Ways Research Could Save the NHS Money – NIHR Highlight (free)

 

5 – Evidence for HIV-1 cure after CCR5Δ32/Δ32 allogeneic haemopoietic stem-cell transplantation 30 months post analytical treatment interruption: a case report – The Lancet HIV (free)

Commentaries: A cure for HIV: how would we know? – The Lancet HIV (free) AND Second patient has been cured of HIV, study suggests – The Lancet (free) AND Second Patient Cured of HIV Still Clear – Science-Based Medicine (free) AND Second patient cured of HIV, say doctors – BBC (free)

 

6 – A systematic review on the causes of the transmission and control measures of outbreaks in long-term care facilities: Back to basics of infection control – PLOS One (free)

 

7 – Prevention of Psychosis: Advances in Detection, Prognosis, and Intervention – JAMA Psychiatry (free for a limited period)

Author Interview: Prevention of Psychosis—Advances in Detection, Prognosis, and Intervention (free audio)

 

8 – Omega‐3 fatty acids for the primary and secondary prevention of cardiovascular disease – Cochrane Library (free)

Summary: Omega-3 intake for cardiovascular disease – Cochrane Library (free)

Author Interview: Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease – Cochrane Library (free)

Commentary: Omega-3s Show No Overall Benefits for Heart Health or Cancer Prevention – The New York Times (free)

 

9 – Omega-3, omega-6 and total dietary polyunsaturated fat on cancer incidence: systematic review and meta-analysis of randomised trials – British Journal of Cancer (link to abstract – $ for full-text)

Commentary: Omega-3 fats do not protect against cancer – University of East Anglia (free)

 

10 – Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 13 March 2020 Edition

13 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

 


When Guidelines Recommend Shared Decision-making

16 Mar, 2020 | 07:45h | UTC

When Guidelines Recommend Shared Decision-making – JAMA (free)

Author Interview: When Guidelines Recommend Shared Decision-making (free audio)

 


Guideline: The Palliative Care of Patients with Incurable Cancer

16 Mar, 2020 | 07:42h | UTC

The Palliative Care of Patients with Incurable Cancer – Deutsches Ärzteblatt international (free)

 


Position Statement on Heart Transplantation: Patient Eligibility, Selection, and Post-Transplantation Care

13 Mar, 2020 | 08:00h | UTC

Canadian Cardiovascular Society/Canadian Cardiac Transplant Network Position Statement on Heart Transplantation: Patient Eligibility, Selection, and Post-Transplantation Care – Canadian Journal of Cardiology (free for a limited period)

 


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