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Tue March 31 – 10 Stories of The Day!

31 Mar, 2020 | 05:04h | UTC

 

1 – CSC Expert Consensus on Principles of Clinical Management of Patients with Severe Emergent Cardiovascular Diseases during the COVID-19 Epidemic – Circulation

 

2 – Report 13: ­­Estimating the number of infections and the impact of non-pharmaceutical interventions on COVID-19 in 11 European countries – Imperial College London

See also: Summary

 

3 – Estimates of the severity of coronavirus disease 2019: a model-based analysis – The Lancet Infectious Diseases

Commentaries: Likelihood of survival of coronavirus disease 2019 – The Lancet Infectious Diseases AND New coronavirus study reveals increased risks from middle age – The Guardian

 

4 – Efficacy of hydroxychloroquine in patients with COVID-19: results of a randomized clinical trial – medRxiv

 

5 – COVID-19: Risks Related to the Use of Hydroxychloroquine

 

6 – Be it resolved, we are making high-stakes decisions about the COVID-19 pandemic without reliable data. – Munk Debates Podcast

Related Video: Perspectives on the Pandemic with Dr. John Ioannidis

Related Article: Editorial by John P.A. Ioannidis: COVID-19: The Harms of Exaggerated Information and Non‐evidence‐based Measures (free study and commentaries)

 

7 – The Mathematics of Predicting the Course of the Coronavirus – Wired

See also: Mathematics of life and death: How disease models shape national shutdowns and other pandemic policies – Science AND How to model a pandemic – The Conversation AND Coronavirus exposes the problems and pitfalls of modelling – The Guardian AND Systematic review and critical appraisal of prediction models for diagnosis and prognosis of COVID-19 infection – medRxiv

 

8 – SARS-CoV-2–Positive Sputum and Feces After Conversion of Pharyngeal Samples in Patients With COVID-19 – Annals of Internal Medicine

Commentary: COVID-19 found in sputum and feces samples after pharyngeal specimens no longer positive – American College of Physicians

 

9 – “Immunity Certificates” to Leave Lockdown Early?

 

10 – Coronavirus Disease (COVID-19) Updates / 31 March 2020 Edition

31 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

 


The Lancet Commission: Sustainable Care for Children with Cancer

1 Apr, 2020 | 05:37h | UTC

Sustainable care for children with cancer – The Lancet Oncology (free articles – registration required)

 


Expert Consensus: Management of Severe Emergent Cardiovascular Diseases during the COVID-19 Epidemic

31 Mar, 2020 | 04:57h | UTC

CSC Expert Consensus on Principles of Clinical Management of Patients with Severe Emergent Cardiovascular Diseases during the COVID-19 Epidemic – Circulation

 


Estimates of the Severity of COVID-19: A Model-based Analysis

31 Mar, 2020 | 04:53h | UTC

Estimates of the severity of coronavirus disease 2019: a model-based analysis – The Lancet Infectious Diseases

Commentaries: Likelihood of survival of coronavirus disease 2019 – The Lancet Infectious Diseases AND New coronavirus study reveals increased risks from middle age – The Guardian

 


Report: Estimating the Number of Infections and the Impact of Non-pharmaceutical Interventions on COVID-19 in 11 European Countries

31 Mar, 2020 | 04:55h | UTC

Report 13: ­­Estimating the number of infections and the impact of non-pharmaceutical interventions on COVID-19 in 11 European countries – Imperial College London

See also: Summary

 


Debate Podcast: John Ioannidis vs. Sten Vermund – Be It Resolved; We Are Making High-stakes Decisions About the COVID-19 Pandemic Without Reliable Data

31 Mar, 2020 | 04:45h | UTC

Be it resolved, we are making high-stakes decisions about the COVID-19 pandemic without reliable data. – Munk Debates Podcast

Related Video: Perspectives on the Pandemic with Dr. John Ioannidis

Related Article: Editorial by John P.A. Ioannidis: COVID-19: The Harms of Exaggerated Information and Non‐evidence‐based Measures (free study and commentaries)

 


COVID-19: Risks Related to the Use of Hydroxychloroquine

31 Mar, 2020 | 04:48h | UTC

 


Study: SARS-CoV-2–Positive Sputum and Feces After Conversion of Pharyngeal Samples in Patients With COVID-19

31 Mar, 2020 | 04:40h | UTC

SARS-CoV-2–Positive Sputum and Feces After Conversion of Pharyngeal Samples in Patients With COVID-19 – Annals of Internal Medicine

Commentary: COVID-19 found in sputum and feces samples after pharyngeal specimens no longer positive – American College of Physicians

 


[Preprint] COVID-19: Hydroxychloroquine Beneficial in Small Trial

31 Mar, 2020 | 04:51h | UTC

Efficacy of hydroxychloroquine in patients with COVID-19: results of a randomized clinical trial – medRxiv

 


The Mathematics of Predicting the Course of the Coronavirus

31 Mar, 2020 | 04:43h | UTC

The Mathematics of Predicting the Course of the Coronavirus – Wired

See also: Mathematics of life and death: How disease models shape national shutdowns and other pandemic policies – Science AND How to model a pandemic – The Conversation AND Coronavirus exposes the problems and pitfalls of modelling – The Guardian AND Systematic review and critical appraisal of prediction models for diagnosis and prognosis of COVID-19 infection – medRxiv

 


Ethical Considerations in the Allocation of Critical Care Resources When Capacity is Overwhelmed

31 Mar, 2020 | 04:37h | UTC

Ethical considerations in the allocation of critical care resources when capacity is overwhelmed – Canadian Journal of Emergency Medicine

 


Review: Oral Step-Down Therapy for the Treatment of Infective Endocarditis

31 Mar, 2020 | 04:33h | UTC

Evaluation of a Paradigm Shift From Intravenous Antibiotics to Oral Step-Down Therapy for the Treatment of Infective Endocarditis: A Narrative Review – JAMA Internal Medicine (free for a limited period)

Author Interview: Evaluation of the Shift From Intravenous Antibiotics to Oral Step-Down Therapy for Infective Endocarditis (free)

 


“Immunity Certificates” to Leave Lockdown Early?

31 Mar, 2020 | 04:39h | UTC

 


ISCHEMIA Trial: Management of Coronary Disease in Patients with Advanced Kidney Disease

31 Mar, 2020 | 04:29h | UTC

Management of Coronary Disease in Patients with Advanced Kidney Disease – New England Journal of Medicine

Commentary: International Study of Comparative Health Effectiveness With Medical and Invasive Approaches–Chronic Kidney Disease – ISCHEMIA-CKD – American College of Cardiology

 


ISCHEMIA Trial: Health-Status Outcomes with Initial Invasive vs. Conservative Care in Stable Coronary Disease

31 Mar, 2020 | 04:26h | UTC

Health-Status Outcomes with Invasive or Conservative Care in Coronary Disease – New England Journal of Medicine

Commentaries: International Study of Comparative Health Effectiveness With Medical and Invasive Approaches – ISCHEMIA – American College of Cardiology AND NIH-funded studies show stents and surgery no better than medication, lifestyle changes at reducing cardiac events – NIH News Releases

 


ISCHEMIA Trial: Health Status after Invasive or Conservative Care in Coronary and Advanced Kidney Disease

31 Mar, 2020 | 04:31h | UTC

Health Status after Invasive or Conservative Care in Coronary and Advanced Kidney Disease – New England Journal of Medicine

Commentary: International Study of Comparative Health Effectiveness With Medical and Invasive Approaches–Chronic Kidney Disease – ISCHEMIA-CKD – American College of Cardiology

 


ISCHEMIA Trial: Initial Invasive vs. Conservative Strategy for Stable Coronary Disease

31 Mar, 2020 | 04:28h | UTC

Initial Invasive or Conservative Strategy for Stable Coronary Disease – New England Journal of Medicine

Commentaries: International Study of Comparative Health Effectiveness With Medical and Invasive Approaches – ISCHEMIA – American College of Cardiology AND NIH-funded studies show stents and surgery no better than medication, lifestyle changes at reducing cardiac events – NIH News Releases

 


Mon March 30 – 10 Stories of The Day!

30 Mar, 2020 | 02:30h | UTC

 

1 – Venous thromboembolic diseases: diagnosis, management and thrombophilia testing – National Institute for Health and Care Excellence

 

2 – Management of Critically Ill Adults With COVID-19 – JAMA

Editorial: Toward Universal Deployable Guidelines for the Care of Patients With COVID-19

Original Guideline: Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19) – Intensive Care Medicine AND Infographics: The Surviving Sepsis Campaign Rapid Guidelines on the Management of Critically Ill Adults with COVID-19

Related Summary: Surviving Sepsis Campaign: COVID-19 Recommendations – CanadiEm

Related Guideline: COVID-19 rapid guideline: critical care – National Institute for Health and Care Excellence

 

3 – Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma – JAMA

Editorial: Convalescent Plasma to Treat COVID-19: Possibilities and Challenges

Commentaries: A new report raises hope that the blood of recovered patients can help treat severe coronavirus cases – Business Insider AND Plasma transfusion shows promise for COVID-19 treatment, says China study – UPI

See also: Investigational COVID-19 Convalescent Plasma – Emergency INDs – U.S. Food & Drug Administration

 

4 – COVID-19: Controversies on the Use of Face Masks

Related Guidance: WHO Recommendations on when and how to use masks – World Health Organization AND Strategies for Optimizing the Supply of Facemasks – Centers for Disease Control and Prevention

 

5 – N95 Re-Use Instructions – SAGES

Related: Conserving Supply of Personal Protective Equipment—A Call for Ideas – JAMA AND N95 mask can be decontaminated without decreasing filtration efficiency – Stanford Medicine

 

6 – Renin-Angiotensin System Blockers and the COVID-19 Pandemic: At Present There Is No Evidence to Abandon Renin-Angiotensin System Blockers – Hypertension

Commentary: COVID-19 alert: Heart and kidney patients should keep taking their medicines – University of Miami Miller School of Medicine

Related Guidelines: HFSA/ACC/AHA Statement Addresses Concerns Re: Using RAAS Antagonists in COVID-19 – American College of Cardiology AND The Renal Association, UK position statement on COVID-19 and ACE Inhibitor/Angiotensin Receptor Blocker use AND Position Statement of the ESC Council on Hypertension on ACE-Inhibitors and Angiotensin Receptor Blockers – European Society of Cardiology 

Related Article: Is There an Association Between COVID-19 Mortality and the Renin-Angiotensin System—a Call for Epidemiologic Investigations – Clinical Infectious Diseases

 

7 – A War on Two Fronts: Cancer Care in the Time of COVID-19 – Annals of Internal Medicine

Related Guidelines: COVID-19 rapid guideline: delivery of systemic anticancer treatments – National Institute for Health and Care Excellence AND Managing Cancer Care During the COVID-19 Pandemic: Agility and Collaboration Toward a Common Goal – Journal of the National Comprehensive Cancer Network

 

8 – Primary care & Coronavirus (COVID 19): key guidance, information and support – Medium

Related: Coronavirus disease 2019 (covid-19): a guide for UK GPs – The BMJ AND Covid-19: a remote assessment in primary care

 

9 – Potential Effects of Coronaviruses on the Cardiovascular System: A Review – JAMA Cardiology

Editorial: Association of Coronavirus Disease 2019 (COVID-19) With Myocardial Injury and Mortality

Related Articles: Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China – JAMA Cardiology AND Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19) – JAMA Cardiology

Commentary: A Heart Attack? No, It Was the Coronavirus – The New York Times

 

10 – Coronavirus Disease (COVID-19) Updates / 30 March 2020 Edition

30 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

 


JAMA Guideline Synopsis: Management of Critically Ill Adults With COVID-19

30 Mar, 2020 | 02:17h | UTC

Management of Critically Ill Adults With COVID-19 – JAMA

Editorial: Toward Universal Deployable Guidelines for the Care of Patients With COVID-19

Original Guideline: Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19) – Intensive Care Medicine

Related Summary: Surviving Sepsis Campaign: COVID-19 Recommendations – CanadiEm

Related Guideline: COVID-19 rapid guideline: critical care – National Institute for Health and Care Excellence

 


NICE Guideline: Venous Thromboembolic Diseases

30 Mar, 2020 | 02:27h | UTC

Venous thromboembolic diseases: diagnosis, management and thrombophilia testing – National Institute for Health and Care Excellence

 


Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma

30 Mar, 2020 | 02:12h | UTC

Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma – JAMA

Editorial: Convalescent Plasma to Treat COVID-19: Possibilities and Challenges

Commentaries: A new report raises hope that the blood of recovered patients can help treat severe coronavirus cases – Business Insider AND Plasma transfusion shows promise for COVID-19 treatment, says China study – UPI

See also: Investigational COVID-19 Convalescent Plasma – Emergency INDs – U.S. Food & Drug Administration

 


N95 Re-Use Instructions

30 Mar, 2020 | 02:06h | UTC

N95 Re-Use Instructions – SAGES

Related: Conserving Supply of Personal Protective Equipment—A Call for Ideas – JAMA AND N95 mask can be decontaminated without decreasing filtration efficiency – Stanford Medicine

 


COVID-19: Controversies on the Use of Face Masks

30 Mar, 2020 | 02:10h | UTC

Related Guidance: WHO Recommendations on when and how to use masks – World Health Organization AND Strategies for Optimizing the Supply of Facemasks – Centers for Disease Control and Prevention

 


Primary Care & Coronavirus (COVID 19): Key Guidance, Information and Support

30 Mar, 2020 | 01:45h | UTC

Primary care & Coronavirus (COVID 19): key guidance, information and support – Medium

Related: Coronavirus disease 2019 (covid-19): a guide for UK GPs – The BMJ AND Covid-19: a remote assessment in primary care – The BMJ

 

Related Commentary on Twitter

 


A War on Two Fronts: Cancer Care in the Time of COVID-19

30 Mar, 2020 | 01:51h | UTC

A War on Two Fronts: Cancer Care in the Time of COVID-19 – Annals of Internal Medicine

Related Guidelines: COVID-19 rapid guideline: delivery of systemic anticancer treatments – National Institute for Health and Care Excellence AND Managing Cancer Care During the COVID-19 Pandemic: Agility and Collaboration Toward a Common Goal – Journal of the National Comprehensive Cancer Network

 


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