Archives
Randomized Trial: Hypofractionated Breast Radiotherapy for 1 Week Noninferior to 3 weeks
30 Apr, 2020 | 04:02h | UTCCommentaries: 1-week hypofractionated adjuvant whole-breast radiotherapy: towards a new standard? – The Lancet AND One-week course of radiotherapy could benefit women with early stage breast cancer, study finds – Institute of Cancer Research
General Guidelines in the Management of an Obstetrical Patient on the Labor and Delivery Unit during the COVID-19 Pandemic
30 Apr, 2020 | 04:07h | UTC
[Abstract Only] Feasibility of Blood Testing Combined with PET-CT to Screen for Cancer and Guide Intervention
30 Apr, 2020 | 04:00h | UTCFeasibility of blood testing combined with PET-CT to screen for cancer and guide intervention – Science (link to abstract – $ for full-text)
Commentaries: DNA blood test spots cancers in seemingly cancer-free women, but also produces false alarms – Science AND First study of multicancer blood test to screen for cancer guide intervention – Johns Hopkins Medicine
USPSTF Statement: Primary Care Interventions for Prevention and Cessation of Tobacco Use in Children and Adolescents
30 Apr, 2020 | 03:48h | UTCEditorial: Recommendations From the USPSTF for Prevention and Cessation of Tobacco Use in Children and Adolescents (free for a limited period)
Author Interview: USPSTF Recommendation: Tobacco Use Prevention and Cessation in Children and Adolescents
Commentary: USPSTF: Clinicians Should Counsel Kids to Not Start Smoking – NEJM Journal Watch
Clinical Guidelines for the Management of Eosinophilic Esophagitis
30 Apr, 2020 | 03:55h | UTC
Consensus Statement on Fundamental Concepts in Perioperative Fluid Management
30 Apr, 2020 | 03:51h | UTC
Systematic Review: Treating Disseminated Histoplasmosis in People Living with HIV
30 Apr, 2020 | 03:41h | UTCTreating progressive disseminated histoplasmosis in people living with HIV – Cochrane Library
Summary: How best to treat progressive disseminated histoplasmosis in people with HIV – Cochrane Library
[Abstract Only] Randomized Trial: Olaparib for Metastatic Castration-Resistant Prostate Cancer
30 Apr, 2020 | 03:38h | UTCOlaparib for Metastatic Castration-Resistant Prostate Cancer – New England Journal of Medicine
Advances in Regenerative Medicine for Otolaryngology/Head and Neck Surgery
30 Apr, 2020 | 03:45h | UTCAdvances in regenerative medicine for otolaryngology/head and neck surgery – The BMJ
Perspective: Pandemic Science Out of Control
29 Apr, 2020 | 05:20h | UTCPandemic Science Out of Control – Issues in Science and Technology
Related Commentary on Twitter
"Especially in times of crisis, statistically meaningless, methodologically shoddy, and even fraudulent research can find a receptive audience in desperate patients, credulous doctors, and uninformed journalists."
@JeanneLenzer1 & @ShannonBrownlee https://t.co/Jdw3nT3Z8E— Issues in Science and Technology (@ISSUESinST) April 28, 2020
Perspective: What Policy Makers Need to Know About COVID-19 Protective Immunity
29 Apr, 2020 | 05:19h | UTCWhat policy makers need to know about COVID-19 protective immunity – The Lancet
Related: What Covid-19 antibody tests say — and don’t say — about immunity – Vox AND The False Hope of Antibody Tests – The Atlantic AND What Antibody Studies Can Tell You — and More Importantly, What They Can’t – ProPublica AND What if immunity to covid-19 doesn’t last? – MIT Technology Review AND Beware of Antibody-based COVID-19 “Immunity Passports” – Scientific American AND Coronavirus immunity: Can you catch it twice? – BBC
Related Commentary on Twitter
An especially astute and succinct essay on #COVID19 protective immunity @TheLancet todayhttps://t.co/HFGUGPdson
highlights unknowns on duration, role of T lymphocytes, what constitutes real protection, and herd immunity features pic.twitter.com/oBC48DcGCl— Eric Topol (@EricTopol) April 28, 2020
Thu April 30 – 10 Stories of The Day!
30 Apr, 2020 | 04:34h | UTC
Commentaries: First randomized trial of remdesivir suggests antiviral drug is not associated with significant clinical benefits, more research needed – The Lancet AND Expert reaction to trial of remdesivir in adults – Science Media Centre
Commentaries: Hopes rise on coronavirus drug remdesivir – Nature AND The COVID-19 research news rollercoaster is running again: STAT News + Gilead’s remdesivir – HealthNews Review
3 – Pooling of samples for testing for SARS-CoV-2 in asymptomatic people – The Lancet Infectious Diseases AND Commentary: Virologists show that sample pooling can massively increase coronavirus testing capacity – Saarland University
Related Preprint Study: Smart Pooled sample Testing for COVID-19: A Possible Solution for Sparsity of Test Kits – medRxiv AND Commentary: ‘Smart sample pooling’ for COVID-19 could solve test kit shortage problem – News Medical
News Release: COVID-19 study shows that men have over double the death rate of women – Frontiers
6 – Audio Interview: Loosening Covid-19 Restrictions – New England Journal of Medicine
7 – Covid-19 — A Reminder to Reason – New England Journal of Medicine
8 – COVID-19 and its implications for thrombosis and anticoagulation – Blood
10 – Coronavirus Disease (COVID-19) Updates / 30 April 2020 Edition
30 April 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Case Series: Atypical Presentation of COVID-19 in Young Infants
29 Apr, 2020 | 05:17h | UTCAtypical presentation of COVID-19 in young infants – The Lancet
“In the pandemic context, infants younger than 3 months with isolated fever should be tested for SARS-CoV-2. “
Case Series: Characterization of Ischemic Cutaneous Lesions Associated with Covid-19
29 Apr, 2020 | 05:14h | UTCSee also: Journal articles on coronavirus with relevance for skin diseases and dermatology – Centre of Evidence Based Dermatology, University of Nottingham AND From ‘COVID Toes’ to Hives, These Are the Skin Conditions Dermatologists Think Could Be Signs of Coronavirus – TIME
Large-Vessel Stroke as a Presenting Feature of Covid-19 in the Young
29 Apr, 2020 | 05:21h | UTC
Covid-19: Concerns Grow Over Inflammatory Syndrome Emerging in Children
29 Apr, 2020 | 05:16h | UTCCovid-19: concerns grow over inflammatory syndrome emerging in children – The BMJ
Related: UK says some children have died from syndrome linked to COVID-19 – Reuters
Lung Pathology of COVID-19: Is AFOP in Play?
29 Apr, 2020 | 04:58h | UTCLung pathology of COVID-19: is AFOP in play? – PulmCrit
Why Don’t Some Coronavirus Patients Sense their Alarmingly Low Oxygen Levels?
29 Apr, 2020 | 05:11h | UTCWhy don’t some coronavirus patients sense their alarmingly low oxygen levels? – Science
How Sweden Has Faced the Virus Without a Lockdown
29 Apr, 2020 | 04:53h | UTC‘Life Has to Go On’: How Sweden Has Faced the Virus Without a Lockdown – The New York Times
Patients with Cancer More Vulnerable to SARS-COV-2
29 Apr, 2020 | 05:00h | UTCCommentaries: COVID-19 Increases Overall Risk of Death, Complications in Patients With Cancer, Study Shows – AJMC AND Patients with blood and lung cancers are three times more at risk of dying of coronavirus than people with other tumors, study finds – Daily Mail AND Coronavirus: Cancer patients nearly three times more likely to die of Covid-19, study says – Independent
Inpatient Care of Patients with COVID-19: A Guide for Hospitalists
29 Apr, 2020 | 04:55h | UTC
Evaluation and Management of Premature Ventricular Complexes
29 Apr, 2020 | 04:52h | UTCEvaluation and Management of Premature Ventricular Complexes – Circulation (free for a limited period)
Randomized Trial: Beta-Blocker Therapy Promising in Severe Traumatic Brain Injury
29 Apr, 2020 | 04:47h | UTCRelated Meta-Analysis: Beta-Blockers and Traumatic Brain Injury: A Systematic Review and Meta-Analysis – Annals of Surgery
“We recommend further high-quality trials to answer questions about the mechanisms of action, effectiveness on subgroups, dose-response, length of therapy, functional outcome, and quality of life after β-blocker use for TBI” (from the 2017 meta-analysis above)
BTS Guideline for the Use of Long-term Macrolides in Adults with Respiratory Disease
29 Apr, 2020 | 04:49h | UTC
Systematic Review: Antidepressants for Smoking Cessation
29 Apr, 2020 | 04:40h | UTCAntidepressants for smoking cessation – Cochrane Library
Summary: Do medicines used to treat depression help people to quit smoking? – Cochrane Library