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“We must never lose sight of all the other patients who need our care today. Patients with any symptom indicating an emergency or severe disease must NOT stay at home.”

Guidance Statement: Mechanical Thrombectomy in the Era of the COVID-19 Pandemic

11 May, 2020 | 00:32h | UTC

Mechanical Thrombectomy in the Era of the COVID-19 Pandemic: Emergency Preparedness for Neuroscience Teams: A Guidance Statement From the Society of Vascular and Interventional Neurology – Stroke

Commentaries: Guidance for Treating Stroke Patients During COVD-19 Crisis Developed – Boston University School of Medicine AND Mechanical Thrombectomy and Emergency Preparedness Guidance in COVID-19 Era – American College of Cardiology

Sharp Drop in Stroke Evaluations During COVID-19 Pandemic

11 May, 2020 | 00:35h | UTC

Collateral Effect of Covid-19 on Stroke Evaluation in the United States – New England Journal of Medicine

Commentary: Stroke evaluations drop by nearly 40% during COVID-19 pandemic – Washington University School of Medicine

COVID-19 Research in Brief: 2 May to 8 May, 2020

11 May, 2020 | 00:24h | UTC

COVID-19 Research in Brief: 2 May to 8 May, 2020 – Nature Medicine

Canadian Study Finds Temperature, Latitude Not Associated with COVID-19 Spread

11 May, 2020 | 00:30h | UTC

Impact of climate and public health interventions on the COVID-19 pandemic: A prospective cohort study – Canadian Medical Association Journal

News Release: Canadian study finds temperature, latitude not associated with COVID-19 spread – Canadian Medical Association Journal

[Abstract Only] Study: No Increased Risk of Infections with Resterilized and Reused Pacemakers or Defibrillators

11 May, 2020 | 00:21h | UTC

Infections Associated with Resterilized Pacemakers and Defibrillators – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Infections With Resterilized Pacemakers and Defibrillators – American College of Cardiology AND No increased risk of infection with recycled pacemakers and defibrillators – Cardiovascular Business

Revisited: Therapeutic and Toxic Blood Concentrations of More than 1100 drugs and Other Xenobiotics

11 May, 2020 | 00:15h | UTC

Revisited: Therapeutic and toxic blood concentrations of more than 1100 drugs and other xenobiotics – Critical Care

Perspective: When Should Clinicians Act on Non–Statistically Significant Results From Clinical Trials?

11 May, 2020 | 00:23h | UTC

When Should Clinicians Act on Non–Statistically Significant Results From Clinical Trials? – JAMA (via @AndersPerner)

Author Interview: When Should Physicians Act on Non–Statistically Significant Results From Clinical Trials?

“The burden of proof required to do “more” should probably be higher than to do “less,” particularly if doing “more” is likely to increase overall health care costs.”

The Emerging Long-term Complications of Covid-19, Explained

11 May, 2020 | 00:27h | UTC

The emerging long-term complications of Covid-19, explained – Vox

Canadian Guideline: Acetylsalicylic Acid for Prevention of Vascular Events

11 May, 2020 | 00:05h | UTC

Canadian Stroke Best Practice Recommendations, seventh edition: acetylsalicylic acid for prevention of vascular events – Canadian Medical Association Journal

Meta-Analysis: Furosemide Stress Test as a Predictive Marker of Acute Kidney Injury Progression or Renal Replacement Therapy

11 May, 2020 | 00:12h | UTC

Furosemide stress test as a predictive marker of acute kidney injury progression or renal replacement therapy: a systemic review and meta-analysis – Critical Care

Position Paper: Antimicrobial Therapeutic Drug Monitoring in Critically Ill Adult Patients

11 May, 2020 | 00:19h | UTC

Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper – Intensive Care Medicine

Commentary: New antibiotic guidelines could save more lives in intensive care units – News Medical

Study: Combustible vs. Electronic Cigarettes Alterations in Vascular Function

11 May, 2020 | 00:10h | UTC

Alterations in Vascular Function Associated With the Use of Combustible and Electronic Cigarettes – Journal of the American Heart Association

Commentary: Like Tobacco, Long-term E-Cigarettes Harm Vascular Function – TCTMD AND Vascular Damage Similar With E-cigarettes, Traditional Cigarettes – American College of Cardiology

Systematic Review: Pharmacological treatment for Buerger’s disease

10 May, 2020 | 23:58h | UTC

Pharmacological treatment for Buerger’s disease – Cochrane Library

Summary: Pharmacological treatment (drugs) for Buerger’s disease

NCCN Guideline: Hematopoietic Cell Transplantation

10 May, 2020 | 23:53h | UTC

Hematopoietic Cell Transplantation, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology – Journal of the National Comprehensive Cancer Network

Systematic Review: Pelvic Floor Muscle Training for Preventing and Treating Urinary and Fecal Incontinence in Antenatal and Postnatal Women

11 May, 2020 | 00:02h | UTC

Pelvic floor muscle training for preventing and treating urinary and faecal incontinence in antenatal and postnatal women – Cochrane Library

Summary: How effective is pelvic floor muscle training undertaken during pregnancy or after birth for preventing or treating incontinence? – Cochrane Library

Large Observational Study Finds Hydroxychloroquine Provides no Benefit in Hospitalized Patients with Covid-19

8 May, 2020 | 10:41h | UTC

Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19 – New England Journal of Medicine

Editorial: The Urgency of Care during the Covid-19 Pandemic — Learning as We Go

Treatment of Community-Acquired Pneumonia During the COVID-19 Pandemic

8 May, 2020 | 10:35h | UTC

Treatment of Community-Acquired Pneumonia During the Coronavirus Disease 2019 (COVID-19) Pandemic – Annals of Internal Medicine

Podcast: Studying Potential Covid-19 Therapies

8 May, 2020 | 10:38h | UTC

Audio Interview: Studying Potential Covid-19 Therapies – New England Journal of Medicine

Mon May 11 – 10 Stories of The Day!

11 May, 2020 | 00:44h | UTC

1 – Triple combination of interferon beta-1b, lopinavir–ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial – The Lancet

Commentaries: Interferon beta-1b for COVID-19 – The Lancet AND New triple antiviral drug combination shows early promise for treating COVID-19 in phase 2 randomized trial – The Lancet AND A Drug Cocktail Hastens Recovery in Some Coronavirus Patients – The New York Times AND Triple drug therapy helps coronavirus patients recover more quickly, study finds – CNN AND Triple antiviral drug shows early promise in COVID-19 trial – Reuters AND Expert reaction to a study about a phase 2 trial of a triple antiviral drug combination treatment for COVID-19 – Science Media Centre

2 – Do Not Stay at Home: We Are Ready for You – NEJM Catalyst

“We must never lose sight of all the other patients who need our care today. Patients with any symptom indicating an emergency or severe disease must NOT stay at home.”

3 – Surfing the Waves of the COVID-19 Pandemic As A Cardiovascular Clinician – Circulation (PDF)

4 – Collateral Effect of Covid-19 on Stroke Evaluation in the United States – New England Journal of Medicine

Commentary: Stroke evaluations drop by nearly 40% during COVID-19 pandemic – Washington University School of Medicine

5 – Interleukin-1 blockade with high-dose anakinra in patients with COVID-19, acute respiratory distress syndrome, and hyperinflammation: a retrospective cohort study – The Lancet Rheumatology

Commentaries: Expert reaction to study looking at use of arthritis drug anakinra in hospitalised patients with severe COVID-19 – Science Media Centre AND Small study of patients with severe COVID-19 treated with the arthritis drug anakinra finds clinical improvements – The Lancet

6 – Mechanical Thrombectomy in the Era of the COVID-19 Pandemic: Emergency Preparedness for Neuroscience Teams: A Guidance Statement From the Society of Vascular and Interventional Neurology – Stroke

Commentaries: Guidance for Treating Stroke Patients During COVD-19 Crisis Developed – Boston University School of Medicine AND Mechanical Thrombectomy and Emergency Preparedness Guidance in COVID-19 Era – American College of Cardiology

7 – Impact of climate and public health interventions on the COVID-19 pandemic: A prospective cohort study – Canadian Medical Association Journal

News Release: Canadian study finds temperature, latitude not associated with COVID-19 spread – Canadian Medical Association Journal

8 – The emerging long-term complications of Covid-19, explained – Vox

9 – COVID-19 Research in Brief: 2 May to 8 May, 2020 – Nature Medicine

10 – Coronavirus Disease (COVID-19) Updates / 11 May 2020 Edition