Archives
[Preprint] Randomized trial: Convalescent plasma not associated with improved outcomes in Covid-19
9 Sep, 2020 | 09:41h | UTC
Commentary on Twitter
Convalescent Plasma Randomized Controlled Trial (PLACID Trial) in the Management of Moderate #COVID19 (pre-print)
👉 “not associated with reduction in mortality or progression to severe COVID-19”
Link: https://t.co/2ZXnfemsas@GermHunterMD @MackayIM @CT_Bergstrom #IDTwitter pic.twitter.com/yZuOxVhbjL
— Alvin (@alvie_barr) September 8, 2020
The coronavirus is mutating — does it matter?
9 Sep, 2020 | 09:35h | UTCThe coronavirus is mutating — does it matter? – Nature
The immunology of multisystem inflammatory syndrome in children with COVID-19
9 Sep, 2020 | 09:33h | UTCThe Immunology of Multisystem Inflammatory Syndrome in Children with COVID-19 – Cell
Review: Physical medicine and rehabilitation and pulmonary rehabilitation for COVID-19
9 Sep, 2020 | 09:30h | UTC
IDSA Guidance on the treatment of antimicrobial resistant gram-negative infections
9 Sep, 2020 | 09:24h | UTCNews Release: IDSA Releases Guidance On Treatment Of Antimicrobial-Resistant Infections
Commentary on Twitter
The new @IDSAInfo guidance document on the treatment of MDR GN infections is 🔥🔥🔥. This a really practical/pragmatic document and will be of great use to frontline clinicianshttps://t.co/Eoz2vEHppb
— Mike Stevens (@Dr_Mike_Stevens) September 8, 2020
IDSA Podcast: The global health impact of COVID-19
9 Sep, 2020 | 09:26h | UTCThe Global Health Impact of COVID-19 – Infectious Diseases Society of America
Commentary on Twitter
NEW PODCAST 🎙️ "The Global Health Impact of COVID-19"
Listen: https://t.co/Su7sJNq8CZ @CDCgov global health experts Dr. Barbara Marston & Dr. Nancy Knight join us to discuss the agency’s role in responding to the COVID-19 pandemic globally. @CDCGlobal pic.twitter.com/NowVQ301xU
— IDSA (@IDSAInfo) September 8, 2020
Perspective: “When will WE have a vaccine?” — understanding questions and answers about Covid-19 vaccination
9 Sep, 2020 | 09:37h | UTC
Commentary on Twitter
People inquiring about Covid-19 vaccines often want to know when the public can be confident that available vaccines are safe and effective, when a vaccine will be available to people like them, and when uptake will be high enough to enable a return to prepandemic life. #COVID19
— NEJM (@NEJM) September 8, 2020
Guidelines for the management of intravascular catheters in the ICU
9 Sep, 2020 | 09:22h | UTC
Randomized trial: Out-of-hospital tranexamic acid does not improve neurologic outcomes in patients with traumatic brain injury
9 Sep, 2020 | 09:20h | UTCEditorial: Out-of-Hospital Tranexamic Acid for Traumatic Brain Injury
Commentary on Twitter
In this phase II RCT prehospital tranexamic acid, which inhibits breakdown of fibrin clot, did not improve neurologic outcomes at 6 months vs placebo in patients with moderate to severe TBI https://t.co/PHK91YYxK3 @SusanRowellMD
— JAMA (@JAMA_current) September 8, 2020
Podcast: Update on bariatric surgery—2020
9 Sep, 2020 | 09:18h | UTCAudio Clinical Review: Update on Bariatric Surgery—2020 – JAMA
APA Guideline for the treatment of patients with schizophrenia
9 Sep, 2020 | 09:17h | UTC
#ERScongress – [Abstract Only] Phase 2 trial of the DPP-1 inhibitor Brensocatib in bronchiectasis
9 Sep, 2020 | 09:14h | UTCPhase 2 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis – New England Journal of Medicine
Commentary on Twitter
Original Article: Phase 2 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis (WILLOW Trial) #ERScongress
— NEJM (@NEJM) September 7, 2020
#ERScongress – [Abstract Only] Inhaled Molgramostim therapy in autoimmune pulmonary alveolar proteinosis
9 Sep, 2020 | 09:16h | UTC
Commentary on Twitter
Original Article: Inhaled Molgramostim Therapy in Autoimmune Pulmonary Alveolar Proteinosis (IMPALA Trial) #ERScongress
— NEJM (@NEJM) September 7, 2020
Perspective – Let’s get real. No vaccine will work as if by magic, returning us to ‘normal’
8 Sep, 2020 | 01:22h | UTCLet’s get real. No vaccine will work as if by magic, returning us to ‘normal’ – The Guardian
WHO: Emergency use approval is a “temporary solution,” countries should wait for large clinical trials to finish to roll out a COVID-19 vaccine en masse
8 Sep, 2020 | 01:21h | UTC
An ethical framework for global vaccine allocation
8 Sep, 2020 | 01:24h | UTCAn ethical framework for global vaccine allocation – Science
Commentary: Who should get the COVID-19 vaccine first? – University of Pennsylvania School of Medicine
Commentaries on Twitter
How would #COVID19 vaccines be distributed fairly across the globe once they are made available? Prominent philosophers and bioethicists outline the "Fair Priority Model", a 3-phase plan for vaccine distribution in @ScienceMagazine. https://t.co/1gdErzkRRh
— Stanford Ethics (@StanfordEthics) September 7, 2020
A new, three-phase plan for vaccine distribution for #COVID19—called the Fair Priority Model—is “the best embodiment of the ethical values of limiting harms…and recognizing equal concern for all people,” argues this #SciMagPolicyForum. Learn more: https://t.co/WKMvqKgDjl
— Science Magazine (@ScienceMagazine) September 7, 2020
Meta-analysis: Diagnostic characteristics of serological-based COVID-19 testing
8 Sep, 2020 | 01:16h | UTCSource: EvidenceAlerts
Evolution of the COVID-19 vaccine development landscape
8 Sep, 2020 | 01:18h | UTCEvolution of the COVID-19 vaccine development landscape – Nature Reviews Drug Discovery
Can you catch COVID-19 from your neighbor’s toilet?
8 Sep, 2020 | 01:12h | UTCCan you catch COVID-19 from your neighbor’s toilet? – Science
Factors contributing to healthcare professional burnout during the COVID-19 pandemic: A rapid turnaround global survey
8 Sep, 2020 | 01:14h | UTC
COVID-19 is, in the end, an endothelial disease
8 Sep, 2020 | 01:11h | UTCCOVID-19 is, in the end, an endothelial disease – European Heart Journal
Commentary on Twitter
COVID as an infectious disease of the “endothelium”, the lining of blood vessels, transmitted pre-sympyomatically. Explains the sepsis syndrome; explains the clotting/bleeding; explains the kidney failure.
What a nasty, nasty disease.https://t.co/5hlfL5Iik9
— David Fisman (@DFisman) September 7, 2020
Meta-analysis: Chloroquine and Hydroxychloroquine do not improve outcomes in COVID-19
8 Sep, 2020 | 01:08h | UTCRelated Meta-analysis: Antirheumatic Disease Therapies for the Treatment of COVID‐19: A Systematic Review and Meta‐analysis – Arthritis & Rheumatology
Systematic review: Reduction in saturated fat intake for cardiovascular disease
8 Sep, 2020 | 01:07h | UTCReduction in saturated fat intake for cardiovascular disease – Cochrane Library
Summary: Effect of cutting down on the saturated fat we eat on our risk of heart disease – Cochrane Library
Review: Optimal management of acute coronary syndromes in the era of COVID-19
8 Sep, 2020 | 01:09h | UTCOptimal management of acute coronary syndromes in the era of COVID-19 – Heart
Randomized trial: Upper airway surgery vs. medical management for patients with moderate or severe obstructive sleep apnea who failed conventional treatment
8 Sep, 2020 | 01:04h | UTCEffect of Multilevel Upper Airway Surgery vs Medical Management on the Apnea-Hypopnea Index and Patient-Reported Daytime Sleepiness Among Patients With Moderate or Severe Obstructive Sleep Apnea: The SAMS Randomized Clinical Trial – JAMA (free for a limited period)
Commentary: Relief for people who struggle with CPAP masks – Flinders University
Author interview: Treating Obstructive Sleep Apnea
Editorial: Upper Airway Surgery for Obstructive Sleep Apnea (free for a limited period)
Commentary on Twitter
In this preliminary report of the SAMS RCT of adults w moderate or severe #sleepapnea in whom #CPAP failed, combined palatal and tongue surgery reduced the number of apnea-hypopnea events and sleepiness at 6 mos compared w medical management https://t.co/jiU3hMn9ju #ERSCongress
— JAMA (@JAMA_current) September 4, 2020