Archives
Johnson & Johnson Covid-19 vaccine study paused due to unexplained illness in participant
14 Oct, 2020 | 09:31h | UTCJohnson & Johnson Covid-19 vaccine study paused due to unexplained illness in participant – STAT
News Release: Johnson & Johnson Temporarily Pauses All Dosing in Our Janssen COVID-19 Vaccine Candidate Clinical Trials
Commentaries: Johnson & Johnson ‘Pauses’ COVID-19 Vaccine Trial Due To Unexplained Illness In Participant; Eli Lilly Reportedly Suspending Trial Of Antibody Treatment – Health Policy Watch AND Johnson & Johnson pauses Covid-19 vaccine trial after ‘unexplained illness’ – CNN
Non-respiratory presentations of COVID-19, a clinical review
14 Oct, 2020 | 09:33h | UTC
Monoclonal antibody trial halted for safety concern
14 Oct, 2020 | 09:30h | UTCMonoclonal Antibody Trial Halted for Safety Concern – Brief19
Covid-19: how to prioritize worse-off populations in allocating safe and effective vaccines
14 Oct, 2020 | 09:25h | UTC
COVID-19 will probably become endemic – here’s what that means
14 Oct, 2020 | 09:27h | UTCCOVID-19 will probably become endemic – here’s what that means – The Conversation
[Abstract Only] Randomized trials: Efficacy and safety of a plant-derived influenza vaccine in adults
14 Oct, 2020 | 09:23h | UTCEfficacy, immunogenicity, and safety of a plant-derived, quadrivalent, virus-like particle influenza vaccine in adults (18–64 years) and older adults (≥65 years): two multicentre, randomised phase 3 trials – The Lancet (link to abstract – $ for full-text)
Commentary on Twitter
NEW—First large-scale studies of plant-derived, quadrivalent, virus-like particle influenza vaccine show substantial protection against respiratory illness & influenza-like illness caused by influenza viruses in adults: two randomised phase 3 trials https://t.co/oQbs2uJTXY pic.twitter.com/C6b6Qi6qZ7
— The Lancet (@TheLancet) October 13, 2020
Case report: Sudden irreversible hearing loss post COVID-19
14 Oct, 2020 | 09:24h | UTCSudden irreversible hearing loss post COVID-19 – BMJ Case Reports
Commentaries: Coronavirus: Patient has sudden permanent hearing loss – BBC AND First reported UK case of sudden permanent hearing loss linked to COVID-19 – BMJ
Commentary on Twitter
Sudden hearing loss after #COVID19.
Report of 1st UK case and review of the other 4 published reports (must be *extremely rare*)https://t.co/wCkrgHcwKH pic.twitter.com/onQxxYiImb— Eric Topol (@EricTopol) October 13, 2020
Meta-analysis: Nonpharmacologic interventions for reducing blood pressure in adults with prehypertension to established hypertension
14 Oct, 2020 | 09:20h | UTC
Commentary on Twitter
Which lifestyle intervention works best for hypertension? #Bayesian meta-analysis suggests the #DASH diet https://t.co/1CgLVwN4LB #AHAJournals @tinauchojo pic.twitter.com/wzJ87OPT0m
— JAHA (@JAHA_AHA) October 5, 2020
Meta-analysis: Overall and cause-specific mortality in randomized clinical trials comparing percutaneous interventions with coronary bypass surgery
14 Oct, 2020 | 09:16h | UTCOverall and Cause-Specific Mortality in Randomized Clinical Trials Comparing Percutaneous Interventions With Coronary Bypass Surgery: A Meta-analysis – JAMA Internal Medicine (free for a limited period)
Commentary on Twitter
In an analysis of 23 randomized trials comparing CABG and PCI, PCI was associated with higher rates of cardiac, non-cardiac, and all-cause mortality. All-cause mortality should be used as endpoint in revascularization trials https://t.co/DBSvVkr3EK
— JAMA Internal Medicine (@JAMAInternalMed) October 12, 2020
Meta-analysis: Association of receipt of palliative care interventions with health care use, quality of life, and symptom burden among adults with chronic noncancer illness
14 Oct, 2020 | 09:18h | UTCEditorial: Palliative Care for Patients With Noncancer Illnesses
Commentary on Twitter
In this meta-analysis of RCTs of patients with primarily noncancer illness (mostly heart failure) palliative care was associated w less acute health care use & lower symptom burden, with no difference in quality of life https://t.co/ZtH6w48vz4 @kieranlquinn
— JAMA (@JAMA_current) October 13, 2020
Opinion piece by Dr. John P.A. Ioannidis: Global perspective of COVID‐19 epidemiology for a full‐cycle pandemic
13 Oct, 2020 | 01:15h | UTC
Pursuing COVID ‘herd immunity’ without a vaccine could be dangerous & unethical, WHO warns
13 Oct, 2020 | 01:16h | UTC
Review: Coagulopathy, venous thromboembolism, and anticoagulation in patients with COVID‐19
13 Oct, 2020 | 01:12h | UTC
[Preprint] Exclusion of bacterial co-infection in COVID-19 using baseline inflammatory markers and their response to antibiotics
13 Oct, 2020 | 01:08h | UTC
Commentary on Twitter
Anyone think we prescribe too many #antibiotics in #COVID19?
Looking for ways to prescribe less?
Well, our latest *PREPRINT* (not peer reviewed!) may be of interest. #antibioticstewardship https://t.co/qUimnZhwg7 Thread (1/7) pic.twitter.com/Z6gaGMgduv— Gabriele Pollara (@gpollara) October 12, 2020
Study: Metallodrug ranitidine bismuth citrate suppresses SARS-CoV-2 replication and relieves virus-associated pneumonia in Syrian hamsters
13 Oct, 2020 | 01:10h | UTC
Commentary on Twitter
👨⚕️ Researchers from @HKUniversity test a set of metallodrugs and related compounds, and identify ranitidine bismuth citrate, a commonly used drug for the treatment of Helicobacter pylori #infection, as a potent anti-#SARS-CoV-2 agent.
👁️ Full article https://t.co/Oz5O7hL9js pic.twitter.com/izMRdRTT27
— Immunology of Infectious Disease News (@infdisease_news) October 12, 2020
Outcomes of neonates born to mothers with SARS-CoV-2 Infection
13 Oct, 2020 | 01:05h | UTCEditorial: Balancing Risks in the Time of COVID-19
Commentary: Very low risk to newborns from moms with COVID-19, finds study – Columbia University Irving Medical Center
Excess deaths from Covid-19 and other causes in the US
13 Oct, 2020 | 01:06h | UTCExcess Deaths From COVID-19 and Other Causes, March-July 2020 – JAMA
Editorials: Excess Deaths and the Great Pandemic of 2020 AND The Toll of COVID-19
Video: Excess Deaths During the Coronavirus Pandemic
Related Research: COVID-19 and Excess All-Cause Mortality in the US and 18 Comparison Countries – JAMA AND Mental Health Disorders Related to COVID-19–Related Deaths – JAMA
The effect of temperature on persistence of SARS-CoV-2 on common surfaces
13 Oct, 2020 | 01:04h | UTCThe effect of temperature on persistence of SARS-CoV-2 on common surfaces – Virology Journal
Commentaries: Study: Covid-19 Coronavirus May Survive For 28 Days On These Surfaces – Forbes AND Covid virus ‘survives for 28 days’ in lab conditions – BBC
‘Long Covid’: Why are some people not recovering?
13 Oct, 2020 | 01:03h | UTC‘Long Covid’: Why are some people not recovering? – BBC
Infecting volunteers with coronavirus may be one way to test potential vaccines. But there are risks.
13 Oct, 2020 | 01:02h | UTC
Research integrity: Nine ways to move from talk to walk
13 Oct, 2020 | 01:01h | UTCResearch integrity: nine ways to move from talk to walk – Nature
Initiative pushes to make journal abstracts free to read in one place
13 Oct, 2020 | 01:00h | UTCInitiative pushes to make journal abstracts free to read in one place – Nature
The end of dengue fever? Mosquito experiment in Indonesia sees huge reduction in cases
13 Oct, 2020 | 00:59h | UTC
Meta-analysis: ECMO for severe ARDS
13 Oct, 2020 | 00:58h | UTC
Commentary on Twitter
#ECMO vs conventional strategies in severe #ARDS, meta-analysis of individual patient data:#ECMO-group pts spent more days alive out of the #ICU & without respiratory, cardiovascular, renal, neurological failure. Open access @yourICM #FOAMcc #FOAMecmo https://t.co/3PV2gAHA3G https://t.co/k6MQYUjKgu
— Intensive Care Medicine (@yourICM) October 7, 2020
Cohort study: ‘COVID-19 free’ hospital areas linked to improved outcomes in elective cancer surgery
12 Oct, 2020 | 00:48h | UTCCommentary: ‘COVID-19 free’ hospital areas could save lives after surgery, global study finds – University of Birmingham