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American Clinical Neurophysiology Society’s Standardized Critical Care EEG Terminology: 2021 Version

25 Jan, 2021 | 01:15h | UTC

American Clinical Neurophysiology Society’s Standardized Critical Care EEG Terminology: 2021 Version – Journal of Clinical Neurophysiology

 

Cohort study: Long-term clinical outcomes of hematopoietic stem cell transplantation in 210 patients with multiple sclerosis

25 Jan, 2021 | 01:15h | UTC

Long-Term Clinical Outcomes of Hematopoietic Stem Cell Transplantation in Multiple Sclerosis – Neurology (link to abstract – $ for full-text)

 

Machine Learning and the Future of Cardiovascular Care: JACC State-of-the-Art Review

25 Jan, 2021 | 01:08h | UTC

Machine Learning and the Future of Cardiovascular Care: JACC State-of-the-Art Review – Journal of the American College of Cardiology

 

Commentary on Twitter

 

Randomized trial: First-line nivolumab plus ipilimumab combined with two cycles of chemotherapy in patients with non-small-cell lung cancer

25 Jan, 2021 | 01:12h | UTC

First-line nivolumab plus ipilimumab combined with two cycles of chemotherapy in patients with non-small-cell lung cancer (CheckMate 9LA): an international, randomised, open-label, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)

Commentary: First-line Nivolumab and Ipilimumab Plus Chemotherapy Improves OS in NSCLC – AJMC

 

Randomized trial: First-line nivolumab plus ipilimumab in unresectable malignant pleural mesothelioma

25 Jan, 2021 | 01:13h | UTC

First-line nivolumab plus ipilimumab in unresectable malignant pleural mesothelioma (CheckMate 743): a multicentre, randomised, open-label, phase 3 trial – The Lancet (link to abstract – $ for full-text)

 

[Press Release – Not Published Yet] Colchicine reduces the risk of COVID-19-related complications: Positive results from COLCORONA trial show that colchicine is the only effective oral medication for treating non-hospitalized patients

25 Jan, 2021 | 01:43h | UTC

Colchicine reduces the risk of COVID-19-related complications: Positive results from COLCORONA trial show that colchicine is the only effective oral medication for treating non-hospitalized patients – Montreal Heart Insititute

Study Protocol: Colchicine Coronavirus SARS-CoV2 Trial (COLCORONA) (COVID-19) – ClinicalTrials.gov

“Patients will receive study medication colchicine 0.5 mg per os (PO) twice daily for the first 3 days and then once daily for the last 27 days.”

Commentaries: ‘Major breakthrough’ | Large study shows effectiveness of colchicine to treat COVID-19 – The Canadian AND A gout drug shows promise for Covid-19, but skeptics worry about trusting science by press release – STAT

 

Commentary on Twitter

 

[Press Release – Not Published Yet] Full-dose blood thinners decreased need for life support and improved outcome in hospitalized COVID-19 patients

25 Jan, 2021 | 01:42h | UTC

Full-dose blood thinners decreased need for life support and improved outcome in hospitalized COVID-19 patients – National Institutes of Health

 

Randomized trial: Bamlanivimab associated with Etesevimab reduce the viral load in patients with mild to moderate COVID-19

25 Jan, 2021 | 01:36h | UTC

Effect of Bamlanivimab as Monotherapy or in Combination With Etesevimab on Viral Load in Patients With Mild to Moderate COVID-19: A Randomized Clinical Trial – JAMA

Editorial: Neutralizing Monoclonal Antibody for Mild to Moderate COVID-19

 

Randomized trial: Anakinra (IL-1 receptor antagonist) does not improve outcomes in patients with mild-to-moderate COVID-19

25 Jan, 2021 | 01:37h | UTC

Effect of anakinra versus usual care in adults in hospital with COVID-19 and mild-to-moderate pneumonia (CORIMUNO-ANA-1): a randomised controlled trial – The Lancet Respiratory Medicine

Commentary: The right place for IL-1 inhibition in COVID-19 – The Lancet Respiratory Medicine

 

Commentary on Twitter

 

Revisiting the UK’s strategy for delaying the second dose of the Pfizer covid-19 vaccine

25 Jan, 2021 | 01:32h | UTC

Revisiting the UK’s strategy for delaying the second dose of the Pfizer covid-19 vaccine – The BMJ Opinion

 

Commentary on Twitter

 

Systematic review: At least one third of SARS-CoV-2 infections are asymptomatic

25 Jan, 2021 | 01:33h | UTC

The Proportion of SARS-CoV-2 Infections That Are Asymptomatic: A Systematic Review – Annals of Internal Medicine

Commentary from the authors: The day we let Covid-19 spin out of control – STAT

 

CDC Report: Allergic reactions including anaphylaxis after receipt of the first dose of Moderna COVID-19 vaccine

25 Jan, 2021 | 01:29h | UTC

Allergic Reactions Including Anaphylaxis After Receipt of the First Dose of Moderna COVID-19 Vaccine — United States, December 21, 2020–January 10, 2021 – CDC Morbidity and Mortality Weekly Report

Commentary: CDC reports rare allergic reactions to Moderna’s Covid-19 vaccine – STAT

 

Managing the long term effects of covid-19: summary of NICE, SIGN, and RCGP rapid guideline

25 Jan, 2021 | 01:35h | UTC

Managing the long term effects of covid-19: summary of NICE, SIGN, and RCGP rapid guideline – The BMJ

Original Guideline: COVID-19 rapid guideline: managing the long-term effects of COVID-19 – National Institute for Health and Care Excellence

 

Covid-19: Reports from Israel suggest one dose of Pfizer vaccine could be less effective than expected

25 Jan, 2021 | 01:30h | UTC

Covid-19: Reports from Israel suggest one dose of Pfizer vaccine could be less effective than expected – The BMJ Opinion

 

Randomized trial: No benefit from corticosteroid nasal spray for recovery of smell sensation in COVID-19 patients

25 Jan, 2021 | 01:28h | UTC

Corticosteroid nasal spray for recovery of smell sensation in COVID-19 patients: A randomized controlled trial – American Journal of Otolaryngology

 

Lung and thymic carcinoids: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

25 Jan, 2021 | 01:11h | UTC

Lung and thymic carcinoids: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up – Annals of Oncology

 

Systematic Review: Topical antibiotic prophylaxis to reduce respiratory tract infections and mortality in adults receiving mechanical ventilation

25 Jan, 2021 | 01:05h | UTC

Topical antibiotic prophylaxis to reduce respiratory tract infections and mortality in adults receiving mechanical ventilation – Cochrane Library

Summary: Topical antibiotics to help reduce death and respiratory infections in people in intensive care receiving mechanical ventilation – Cochrane Library

 

Study: Compression garment reduces orthostatic tachycardia and symptoms in patients with postural orthostatic tachycardia syndrome

25 Jan, 2021 | 01:10h | UTC

Compression Garment Reduces Orthostatic Tachycardia and Symptoms in Patients With Postural Orthostatic Tachycardia Syndrome – Journal of the American College of Cardiology (link to abstract – $ for full-text)

 

Meta-analysis: Does near-infrared fluorescent cholangiography with indocyanine green reduce bile duct injuries and conversions to open surgery during laparoscopic or robotic cholecystectomy?

25 Jan, 2021 | 01:06h | UTC

Does near-infrared fluorescent cholangiography with indocyanine green reduce bile duct injuries and conversions to open surgery during laparoscopic or robotic cholecystectomy? — A meta-analysis – Surgery (link to abstract – $ for full-text)

 

Reporting incidental coronary, aortic valve and cardiac calcification on non-gated thoracic computed tomography, a consensus statement from the BSCI/BSCCT and BSTI

25 Jan, 2021 | 01:02h | UTC

Reporting incidental coronary, aortic valve and cardiac calcification on non-gated thoracic computed tomography, a consensus statement from the BSCI/BSCCT and BSTI – BIR Open

 

Randomized trial: No difference in postoperative cognition with intravenous (propofol-based) vs. volatile (sevoflurane-based) anesthetics in elderly patients undergoing laparoscopic abdominal surgery

25 Jan, 2021 | 00:57h | UTC

Intravenous versus Volatile Anesthetic Effects on Postoperative Cognition in Elderly Patients Undergoing Laparoscopic Abdominal Surgery: A Multicenter, Randomized Trial – Anesthesia (link to abstract – $ for full-text)

 

Systematic review: Indomethacin for symptomatic patent ductus arteriosus in preterm infants

25 Jan, 2021 | 01:02h | UTC

Indomethacin for symptomatic patent ductus arteriosus in preterm infants – Cochrane Library

Summary: Indomethacin for treatment of symptomatic patent ductus arteriosus (PDA) in preterm infants – Cochrane Library

 

STaRT-RWE: structured template for planning and reporting on the implementation of real world evidence studies

25 Jan, 2021 | 00:59h | UTC

STaRT-RWE: structured template for planning and reporting on the implementation of real world evidence studies – The BMJ

 

Commentary on Twitter

 

5 Important Things To Know About Extended Spectrum Beta-Lactamases (ESBL): Insights From A Clinical Microbiologist

25 Jan, 2021 | 00:58h | UTC

5 Important Things To Know About Extended Spectrum Beta-Lactamases (ESBL): Insights From A Clinical Microbiologist – IDStewardship

 

[News release – Not published yet] Lilly’s neutralizing antibody prevented COVID-19 at nursing homes, reducing risk by up to 80 percent for residents

22 Jan, 2021 | 08:40h | UTC

Lilly’s neutralizing antibody bamlanivimab (LY-CoV555) prevented COVID-19 at nursing homes in the BLAZE-2 trial, reducing risk by up to 80 percent for residents

Commentaries: Eli Lilly says its monoclonal antibody prevented Covid-19 infections in clinical trial – STAT AND Expert reaction to press release from Lilly about their neutralising antibody bamlanivimab and results from the BLAZE-2 trial looking at prevention of COVID-19 in nursing homes in the US – Science Media Centre

 

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