Archives
Decentralized clinical trials: Collaboration is needed to drive their adoption and impact
1 Feb, 2021 | 01:40h | UTCDecentralized clinical trials: Collaboration is needed to drive their adoption and impact – STAT
Blood test to detect psychogenic nonepileptic seizures shows promise
1 Feb, 2021 | 01:37h | UTCBlood Test to Detect Psychogenic Nonepileptic Seizures Shows Promise – Physician’s Weekly
Original study: Association of Epileptic and Non-epileptic Seizures and Changes in Circulating Plasma Proteins Linked to Neuroinflammation – Neurology (link to abstract – $ for full-text)
An analysis of contemporary oncology randomized clinical trials from low/middle-income vs. high-income countries
1 Feb, 2021 | 01:36h | UTCAn Analysis of Contemporary Oncology Randomized Clinical Trials From Low/Middle-Income vs High-Income Countries – JAMA Oncology (free for a limited period)
ASCO Guideline: Neoadjuvant chemotherapy, endocrine therapy, and targeted therapy for breast cancer
1 Feb, 2021 | 01:34h | UTC
Consensus statement recommends individualizing surveillance mammography for older patients after treatment for early-stage breast cancer
1 Feb, 2021 | 01:33h | UTCCommentaries: First Mammography Guidelines Released for Older Breast Cancer Survivors – Diagnostic Imaging AND New Surveillance Mammography Screening Guidelines Issued for Breast Cancer Survivors Aged 75 and Older – The ASCO Post
[Not published yet] Full-dose Heparin best for moderate COVID-19 regardless of D-dimer — Data released from ACTIV-4a, ATTACC, and REMAP-CAP trials
1 Feb, 2021 | 01:58h | UTCFull-Dose Heparin Best for Moderate COVID-19 Regardless of D-dimer — Data released from ACTIV-4a, ATTACC, and REMAP-CAP trials – MedPage Today (free registration required)
Trial results: ATTACC, ACTIV-4a & REMAP-CAP multiplatform RCT Results of interim analysis – ATTACC Trial
New Updates to the Surviving Sepsis Campaign COVID-19 Guidelines
1 Feb, 2021 | 01:56h | UTCAdditional resources: COVID-19 Guidelines – Surviving Sepsis Campaign
Commentary on Twitter
New updates to the #SurvivingSepsis Campaign #COVID19 Guidelines! Includes new recommendations for therapeutics and defines severe vs critical COVID-19.
View the full update in @CritCareMed, more infographics, and recommendations table here: https://t.co/OUuOwGJCR4#SCCMSoMe pic.twitter.com/1RGckdvoIm
— SCCM (@SCCM) January 30, 2021
Analysis: J&J and Novavax Data
1 Feb, 2021 | 01:54h | UTCJ&J and Novavax Data – In the Pipeline
[Press release – not published yet] Single-shot Janssen COVID-19 vaccine candidate met primary endpoints in interim analysis of its phase 3 trial
1 Feb, 2021 | 01:55h | UTCCommentaries: J&J’s one-shot COVID vaccine offers hope for faster protection – Nature AND Johnson & Johnson Executive Says Vaccine Works Where It Counts: Preventing Deaths – NPR AND Novavax’s COVID Vaccine Shows High Efficacy In Trials; J&J One-Dose Shot Less So – As Europe Feuds With AstraZeneca – Health Policy Watch AND Covid vaccine: Single-dose Johnson & Johnson jab is 66% effective – BBC AND Johnson & Johnson’s COVID-19 Vaccine Results Are Better Than They May Sound – TIME AND Expert reaction to Johnson & Johnson announcing that the single-shot Janssen COVID-19 vaccine candidate met primary endpoints in the interim analysis of its phase 3 ENSEMBLE Trial – Science Media Centre AND Janssen Investigational COVID-19 Vaccine: Interim Analysis of Phase 3 Clinical Data Released – NIH News Releases AND J&J one-dose Covid vaccine is 66% effective, a weapon but not a knockout punch – STAT
SARS-CoV-2 vaccines and the growing threat of viral variants
1 Feb, 2021 | 01:50h | UTCSARS-CoV-2 Vaccines and the Growing Threat of Viral Variants – JAMA
How to redesign COVID vaccines so they protect against variants: lineages that can evade immunity are spurring vaccine makers to explore ways to redesign their shots
1 Feb, 2021 | 01:52h | UTCHow to redesign COVID vaccines so they protect against variants – Nature
See also: Vaccine 2.0: Moderna and other companies plan tweaks that would protect against new coronavirus mutations – Science (a few articles per month are free)
The most worrying mutations in five emerging coronavirus variants
1 Feb, 2021 | 01:50h | UTCThe Most Worrying Mutations in Five Emerging Coronavirus Variants – Scientific American
Analysis: Covid-19 pandemic and the social determinants of health
1 Feb, 2021 | 01:49h | UTCCovid-19 pandemic and the social determinants of health – The BMJ
Public health actions to control new SARS-CoV-2 variants
1 Feb, 2021 | 01:47h | UTCPublic health actions to control new SARS-CoV-2 variants – Cell
Commentary on Twitter (thread – click for more)
*Public health actions to control new SARS-CoV-2 variants*
Our paper just published in @CellCellPress w wonderful co-authors @NathanGrubaugh @firefoxx66 @JosephFauver & @mugecevik
We describe actions govts should urgently take to protect health.
— Dr Alexandra Phelan (@alexandraphelan) January 29, 2021
Explaining covid-19 performance: 10 factors might predict national responses
1 Feb, 2021 | 01:48h | UTCExplaining covid-19 performance: what factors might predict national responses? – The BMJ
Commentary on Twitter
https://twitter.com/martinmckee/status/1355040216097165317
WHO issues new 10-year plan to end suffering from neglected tropical diseases
29 Jan, 2021 | 01:39h | UTCNews release: WHO issues new 10-year plan to end suffering from neglected tropical diseases – World Health Organization
Report, executive summary and more: Ending the neglect to attain the Sustainable Development Goals: A road map for neglected tropical diseases 2021–2030 – World Health Organization
Commentary on Twitter (thread – click for more)
In 1⃣ decade, significant progress was achieved to #beatNTDs, with 42 countries 🌐 eliminating at least 1 disease.
The 🆕 roadmap for neglected tropical diseases 2021-2030 builds on this success to ↗️ progress & to contribute to reaching @GlobalGoalsUN
👉https://t.co/tsd5FP3z01 pic.twitter.com/6ydlIZBElp
— World Health Organization (WHO) (@WHO) January 28, 2021
WHO announces updated definitions of extensively drug-resistant tuberculosis
29 Jan, 2021 | 01:38h | UTC
WHO issues new guidelines on the management of chronic pain in children
29 Jan, 2021 | 01:37h | UTCGuideline: Guidelines on the management of chronic pain in children – World Health Organization
Management of diabetes and hyperglycemia in the hospital
29 Jan, 2021 | 01:34h | UTCManagement of diabetes and hyperglycaemia in the hospital – The Lancet Diabetes & Endocrinology (free for a limited period)
Commentary on Twitter
https://twitter.com/TheLancetEndo/status/1354754451161100288
Lancet Series on women’s and children’s health in conflict settings
29 Jan, 2021 | 01:33h | UTCLancet Series on Women’s and Children’s Health in Conflict Settings – The Lancet (free registration required for all articles)
Systematic review: Worldwide incidence and prevalence of Neuromyelitis Optica
29 Jan, 2021 | 01:31h | UTCWorldwide Incidence and Prevalence of Neuromyelitis Optica: A Systematic Review – Neurology
Leading cardiovascular organizations call for urgent action to reduce air pollution
29 Jan, 2021 | 01:36h | UTCPress release: Leading cardiovascular organizations call for urgent action to reduce air pollution – American College of Cardiology
Randomized trial: Effect of diacerein vs. celecoxib on symptoms in knee osteoarthritis
29 Jan, 2021 | 01:30h | UTCCommentary: Noninferiority of diacerein to celecoxib demonstrated for knee OA pain – Medwire News
Radiation therapy for small-cell lung cancer: ASCO Guideline endorsement of an ASTRO Guideline
29 Jan, 2021 | 01:27h | UTC
Randomized trial: Continuous postoperative pericardial flushing reduces postoperative bleeding after coronary artery bypass grafting
29 Jan, 2021 | 01:28h | UTC