Archives

Few pro athletes had inflammatory heart disease after COVID

9 Mar, 2021 | 02:41h | UTC

Few pro athletes had inflammatory heart disease after COVID – CIDRAP

Original study: Prevalence of Inflammatory Heart Disease Among Professional Athletes With Prior COVID-19 Infection Who Received Systematic Return-to-Play Cardiac Screening – JAMA Cardiology

 

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Gabapentin add‐on treatment for drug‐resistant focal epilepsy

9 Mar, 2021 | 02:11h | UTC

Gabapentin add‐on treatment for drug‐resistant focal epilepsy – Cochrane Library

Summary: Gabapentin as an add-on for drug-resistant focal epilepsy – Cochrane Library

 

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Clinical Update: Diagnosis and treatment of irritable bowel syndrome

9 Mar, 2021 | 02:21h | UTC

Diagnosis and Treatment of Irritable Bowel Syndrome: A Review – JAMA (free for a limited period)

Podcast: Irritable Bowel Syndrome—Diagnosis and Treatment – JAMA

 

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Position statement: Imaging in scrotal trauma

9 Mar, 2021 | 02:06h | UTC

Imaging in scrotal trauma: a European Society of Urogenital Radiology Scrotal and Penile Imaging Working Group (ESUR-SPIWG) position statement – European Radiology

 

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Cohort study: Elevated blood pressures are common in the emergency department but are they important?

9 Mar, 2021 | 02:04h | UTC

Yes, Your BP Is Up. No, It Doesn’t Matter. – Journal Feed

Original study: Elevated Blood Pressures Are Common in the Emergency Department but Are They Important? A Retrospective Cohort Study of 30,278 Adults – Annals of Emergency Medicine (link to abstract – $ for full-text)

 

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RCT: Primary tumor resection plus chemotherapy vs. chemotherapy alone for colorectal cancer patients with asymptomatic, synchronous unresectable metastases

7 Mar, 2021 | 19:23h | UTC

Primary Tumor Resection Plus Chemotherapy Versus Chemotherapy Alone for Colorectal Cancer Patients With Asymptomatic, Synchronous Unresectable Metastases (JCOG1007; iPACS): A Randomized Clinical Trial – Journal of Clinical Oncology

Original study: No Survival Benefit to Primary Resection Before Chemo in Metastatic Colorectal Cancer – Medscape / Reuters

 

Primary tumor resection followed by chemotherapy in patients with metastatic colorectal cancer doesn't improve survival over chemotherapy alone https://t.co/iOYqjaABzi @JCOG_official #crcsm #JCO pic.twitter.com/RCj2OHEehH

— Journal of Clinical Oncology (@JCO_ASCO) March 5, 2021

 

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Study: Balanced crystalloids vs. saline in critically ill adults with hyperkalemia or acute kidney injury

9 Mar, 2021 | 02:05h | UTC

Can We Use LR for Hyperkalemia? – Journal Feed

Original study: Balanced Crystalloids versus Saline in Critically Ill Adults with Hyperkalemia or Acute Kidney Injury: Secondary Analysis of a Clinical Trial – American Journal of Respiratory and Critical Care Medicine

 

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Cardiovascular disease risk in immune-mediated inflammatory diseases: recommendations for clinical practice

7 Mar, 2021 | 19:20h | UTC

Cardiovascular disease risk in immune-mediated inflammatory diseases: recommendations for clinical practice – Heart

 

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Systematic review: Big data analytics in healthcare

7 Mar, 2021 | 19:24h | UTC

Big data analytics in healthcare: a systematic literature review – Enterprise Information Systems

 

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Systematic review: High‐flow nasal cannula for respiratory support in adult intensive care patients

7 Mar, 2021 | 19:31h | UTC

High‐flow nasal cannula for respiratory support in adult intensive care patients – Cochrane Library

Summary: High-flow nasal cannulae for breathing support in adult intensive care patients – Cochrane Library

 

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RCT: Half-dose vs. full-dose Edoxaban in 14,014 patients with Atrial Fibrillation

7 Mar, 2021 | 19:13h | UTC

Randomized, Double-Blind Comparison of Half-Dose Versus Full-Dose Edoxaban in 14,014 Patients With Atrial Fibrillation – Journal of the American College of Cardiology

Commentary: Lower Dose of Edoxaban Supported in ENGAGE-AF-TIMI 48 Analysis – TCTMD

 

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Guidance: Perplexing Presentations (PP)/Fabricated or Induced Illness (FII) in Children

7 Mar, 2021 | 19:29h | UTC

Perplexing Presentations (PP)/Fabricated or Induced Illness (FII) in Children Guidance – Royal College of Paediatrics and Child Health

Commentary: Fabricated or induced illness in children highlighted in new guidance – University College London

 

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RECOVERY trial: Colchicine arm stopped for lack of efficacy in patients hospitalized with COVID-19

7 Mar, 2021 | 20:16h | UTC

RECOVERY trial closes recruitment to colchicine treatment for patients hospitalised with COVID-19 – University of Oxford

Commentary: Cochicine does not improve mortality in COVID19 – St Emlyn’s

 

Commentary on Twitter

RECOVERY trial update:

Colchicine arm stopped for lack of efficacy in patients hospitalised with COVID-19.https://t.co/hcn9PytegJ pic.twitter.com/q09eddYXYL

— Martin Landray (@MartinLandray) March 5, 2021

 

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RCT: Azithromycin provides no benefit for community treatment of patients with suspected COVID-19

7 Mar, 2021 | 20:15h | UTC

Azithromycin for community treatment of suspected COVID-19 in people at increased risk of an adverse clinical course in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial – The Lancet

 

Commentary on Twitter

The PRINCIPLE trial publishes its first peer reviewed paper, showing results from the study of azithromycin as a treatment for Covid-19 in the community. @TheLancet #UrgentCovidResearch #PRINCIPLETrial
👉https://t.co/qKRI5PVpQk pic.twitter.com/BVQztDSvSC

— OxPrimaryCareSci (@OxPrimaryCare) March 5, 2021

 

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WHO: The effects of virus variants on COVID-19 vaccines

7 Mar, 2021 | 20:09h | UTC

The effects of virus variants on COVID-19 vaccines – World Health Organization

 

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Mask mandates and restaurant restrictions tied to fewer Covid-19 illnesses and deaths, CDC study says

7 Mar, 2021 | 20:07h | UTC

Mask mandates and restaurant restrictions tied to fewer Covid-19 illnesses and deaths, CDC study says – CNN

Original study: Association of State-Issued Mask Mandates and Allowing On-Premises Restaurant Dining with County-Level COVID-19 Case and Death Growth Rates — United States, March 1–December 31, 2020 – CDC Morbidity and Mortality Weekly Report

 

Commentary on Twitter

A new @CDCMMWR finds that state-issued mask requirements are associated with the slowing of #COVID19 cases and deaths. Wearing a well-fitting mask consistently and correctly is one of the best ways we can protect ourselves and each other. Learn more: https://t.co/8YtmIMPMY0. pic.twitter.com/BLb56SGb2g

— CDC (@CDCgov) March 5, 2021

 

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[Preprint] Genomics and epidemiology of a novel SARS-CoV-2 lineage P.1 – “P.1 may be 1.4–2.2 times more transmissible and 25-61% more likely to evade protective immunity elicited by previous infection with non-P.1 lineages”

7 Mar, 2021 | 20:05h | UTC

Genomics and epidemiology of a novel SARS-CoV-2 lineage in Manaus, Brazil – medRxiv

Commentary: Brazil variant can reinfect virus survivors; COVID-19 vaccine antibodies pass into breast milk – Reuters

 

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[Preprint] SARS-CoV-2 P.1 variant shows resistance to antibody neutralization

7 Mar, 2021 | 19:53h | UTC

Increased Resistance of SARS-CoV-2 Variant P.1 to Antibody Neutralization – bioRxiv

Commentary: Brazilian SARS-CoV-2 P.1 variant shows resistance to antibody neutralization – News Medical

 

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[Medicine based on data leaks…] Oxford study indicates AstraZeneca vaccine is effective against SARS-CoV-2 Lineage P.1

7 Mar, 2021 | 19:48h | UTC

Exclusive: Oxford study indicates AstraZeneca effective against Brazil variant, source says – Reuters

 

Commentary on Twitter

https://twitter.com/hildabast/status/1368010132781600773

 

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[Preprint] Preliminary study shows Sinovac vaccine may not trigger sufficient antibody response to SARS-CoV-2 Lineage P.1

7 Mar, 2021 | 19:49h | UTC

Levels of SARS-CoV-2 Lineage P.1 Neutralization by Antibodies Elicited after Natural Infection and Vaccination – The Lancet

Commentary: Sinovac vaccine may not trigger sufficient antibody response to Brazil variant: study – Reuters

 

Commentary on Twitter

1) In a preprint (to the Lancet), the new Brazilian #SARSCoV2 variant P.1. was found to reduce the neutralizing ability of post-COVID-19 antibodies by about 6-fold, compared with the B lineage.https://t.co/obYmktWFXr pic.twitter.com/3IPiUjHB3l

— Jonathan Cedernaes (@JCedernaes) March 2, 2021

 

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Diagnosis of non-consensus transient ischemic attacks with focal, negative, and non-progressive symptoms: population-based validation by investigation and prognosis

7 Mar, 2021 | 19:32h | UTC

Diagnosis of non-consensus transient ischaemic attacks with focal, negative, and non-progressive symptoms: population-based validation by investigation and prognosis – The Lancet

 

Commentary on Twitter

Some patients present with symptoms that are considered not definitive for TIA (isolated dysarthria, vertigo, etc). Are these patients at risk for later stroke? Fascinating results in @TheLancet from the Oxford Vascular Study@ESOstroke @WorldStrokeOrg https://t.co/l0tJXseE3Y

— Seemant Chaturvedi (@ChaturvediNeuro) March 5, 2021

 

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[Preprint] Increased risk of hospitalization associated with infection with SARS-CoV-2 Lineage B.1.1.7 in Denmark

7 Mar, 2021 | 19:46h | UTC

Increased Risk of Hospitalisation Associated with Infection with SARS-CoV-2 Lineage B.1.1.7 in Denmark – The Lancet

 

Commentary on Twitter (thread – click for more)

📍~64% MORE SEVERE—The already more contagious #B117 variant from 🇬🇧 is now found to increase risk of #COVID19 hospitalization by 64% versus other strains, says Denmark’s 🇩🇰 CDC. Denmark sequences every cases—their data is the best, & now most worrisome.🧵 https://t.co/F6w2JYEUnM pic.twitter.com/mngJoTBZtl

— Eric Feigl-Ding (@DrEricDing) March 4, 2021

 

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SARS-CoV-2 variant B.1.1.7 is susceptible to neutralizing antibodies elicited by ancestral Spike vaccines

7 Mar, 2021 | 19:43h | UTC

SARS-CoV-2 variant B.1.1.7 is susceptible to neutralizing antibodies elicited by ancestral Spike vaccines – Cell Host & Microbiome

 

Commentary on Twitter (thread – click for more)

Very good and important new data on the UK variant and vaccine response
"B.1.1.7 is not a neutralization escape variant of concern for COVID-19 vaccines"
"B.1.1.7 is unlikely to increase the risk of SARS-CoV-2 re-infection"https://t.co/DWzwBUDwY3 @cellhostmicrobe pic.twitter.com/iQv7mL9MHq

— Eric Topol (@EricTopol) March 4, 2021

 

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New WHO/IAEA publication provides guidance on radiotherapy equipment to fight cancer

7 Mar, 2021 | 19:28h | UTC

News Release: New WHO/IAEA publication provides guidance on radiotherapy equipment to fight cancer – World Health Organization

Technical Document: Technical specifications of radiotherapy equipment for cancer treatment

 

🆕 guidance on the procurement of radiotherapy equipment released today in collaboration with @iaeaorg, aims to improve access to this life-saving #cancer treatment option that is still lacking in many parts of the world 🌎🌍🌏

👉 https://t.co/fnR0q3DDMq pic.twitter.com/21SHSaQGy7

— World Health Organization (WHO) (@WHO) March 5, 2021

 

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Study: Cancer patients benefit from using automated device to manage their symptoms

7 Mar, 2021 | 19:21h | UTC

Cancer patients benefit from using automated device to manage their symptoms – News Medical / University of Leeds

Original study: Phase III Randomized Controlled Trial of eRAPID: eHealth Intervention During Chemotherapy – Journal of Clinical Oncology

Editorial: Benefits of Digital Symptom Monitoring With Patient-Reported Outcomes During Adjuvant Cancer Treatment – Journal of Clinical Oncology

 

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