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[Press release – not published yet] Trial of multi drug-resistant TB treatment ends enrolment early after independent board indicates new regimen is superior

25 Mar, 2021 | 08:10h | UTC

Trial of multi drug-resistant TB treatment ends enrolment early after independent board indicates new regimen is superior – Médecins Sans Frontières

Commentary on Twitter

Promising news improving treatment #MDR #TB https://t.co/Lxjb7LBofy Translating findings to available drugs & diagnostics back it up will be key pic.twitter.com/YGp8d9ixww

— Michael Marks (@dr_michaelmarks) March 24, 2021

Modeling study suggest patients should receive COVID-19 vaccine before surgery to reduce the risk of death

26 Mar, 2021 | 08:43h | UTC

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study – University of Birmingham

Original study: SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study – British Journal of Surgery

M-A: Outpatient Cervical Ripening

25 Mar, 2021 | 08:07h | UTC

Outpatient Cervical Ripening: A Systematic Review and Meta-analysis – Obstetrics & Gynecology

RCT: Effect of Intrawound Vancomycin Powder in Operatively Treated High-risk Tibia Fractures

25 Mar, 2021 | 08:04h | UTC

Effect of Intrawound Vancomycin Powder in Operatively Treated High-risk Tibia Fractures: A Randomized Clinical Trial – JAMA Surgery (free for a limited period)

Viewpoint | Precision Dosing: A Clinical and Public Health Imperative

25 Mar, 2021 | 07:40h | UTC

Precision Dosing: A Clinical and Public Health Imperative – JAMA

Author interview: Precision Dosing—A Clinical and Public Health Imperative

USPSTF Statement: Current evidence is insufficient to recommend screening for hearing loss in older adults

24 Mar, 2021 | 08:12h | UTC

Screening for Hearing Loss in Older Adults – U.S. Preventive Services Task Force

Editorial: Screening for Hearing Loss in Older Adults: Insufficient Evidence Does Not Mean Insufficient Benefit – JAMA AND United States Preventive Services Task Force Recommendation for Hearing-Loss Screening Among Older Adults: An Opportunity in Insufficient Evidence – AMA Otolaryngology-Head & Neck Surgery AND USPSTF Recommendations for Hearing Loss Screening in Asymptomatic Older Adults—A Case of Missing Evidence and Missing Treatment Options – JAMA Network Open

Evidence Report: Screening for Hearing Loss in Older Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA

Author interview: USPSTF Recommendation: Screening for Hearing Loss in Older Adults – JAMA

JAMA Patient Page: Screening for Hearing Loss in Older Adults

Review: Use of urine electrolytes and urine osmolality in the clinical diagnosis of fluid, electrolytes, and acid-base disorders

25 Mar, 2021 | 08:06h | UTC

Use of Urine Electrolytes and Urine Osmolality in the Clinical Diagnosis of Fluid, Electrolytes, and Acid-Base Disorders – KI Reports

Commentary on Twitter

Do people use Urine K/crt ratio? for K disorders? What about FeK? TTKG is out! @askrenal –this flow chart makes sense to me https://t.co/8o8a7VYTMQ pic.twitter.com/UVZiFPo4vK

— Kenar Jhaveri (@kdjhaveri) February 20, 2021

RCT: Aspirin NOT noninferior to vitamin K antagonists in the treatment of cervical artery dissection

24 Mar, 2021 | 08:09h | UTC

Aspirin versus anticoagulation in cervical artery dissection (TREAT-CAD): an open-label, randomised, non-inferiority trial – The Lancet Neurology (link to abstract – $ for full-text)

International study describes peri-intubation incidence of adverse events in critically ill patients

24 Mar, 2021 | 08:08h | UTC

Intubation Practices and Adverse Peri-intubation Events in Critically Ill Patients From 29 Countries – JAMA (free for a limited period)

Editorial: International Variation in Intubation and Extubation Practices and Adverse Events Among Critically Ill Patients Receiving Mechanical Ventilation – JAMA (free for a limited period)

Observational study of invasive mechanical ventilation discontinuation showed weaning practices varied internationally

24 Mar, 2021 | 08:06h | UTC

Ventilator Weaning and Discontinuation Practices for Critically Ill Patients – JAMA (free for a limited period)

Editorial: International Variation in Intubation and Extubation Practices and Adverse Events Among Critically Ill Patients Receiving Mechanical Ventilation – JAMA (free for a limited period)

WHO Campaign | World Tuberculosis Day 2021: The Clock Is Ticking

24 Mar, 2021 | 08:16h | UTC

World Tuberculosis Day 2021: The Clock Is Ticking – World Health Organization

Perspective | Leveraging Open Science to Accelerate Research

25 Mar, 2021 | 08:37h | UTC

Leveraging Open Science to Accelerate Research – New England Journal of Medicine

Audio Interview: What earlier epidemics teach us about Covid-19

25 Mar, 2021 | 08:33h | UTC

Audio Interview: What Earlier Epidemics Teach Us about Covid-19 – New England Journal of Medicine

Perspective | New SARS-CoV-2 Variants — Clinical, Public Health, and Vaccine Implications

25 Mar, 2021 | 08:34h | UTC

New SARS-CoV-2 Variants — Clinical, Public Health, and Vaccine Implications – New England Journal of Medicine

Systematic review: Rapid, point‐of‐care antigen and molecular‐based tests for diagnosis of SARS‐CoV‐2 infection

25 Mar, 2021 | 08:38h | UTC

Rapid, point‐of‐care antigen and molecular‐based tests for diagnosis of SARS‐CoV‐2 infection – Cochrane Library

Commentaries: Updated Cochrane review assesses how accurate rapid tests are for detecting COVID-19 – Wiley AND Expert reaction to updated Cochrane review of studies on accuracy of rapid tests (including lateral flow and molecular tests) to detect SARS-CoV-2 – Science Media Centre

RCT: Effect of clear vs. standard covered masks on communication with patients during surgical clinic encounters

25 Mar, 2021 | 08:31h | UTC

Effect of Clear vs Standard Covered Masks on Communication With Patients During Surgical Clinic Encounters: A Randomized Clinical Trial – JAMA Surgery

Commentaries: Benefits of Clear Masks in Communication With Patients – JAMA Surgery AND New study shows impact of mask wearing on patient trust and perception of surgeons – University of North Carolina Health Care

Author interview: Clear vs Standard Covered Masks on Communication With Patients During Surgical Clinic Encounters

Commentary on Twitter

Surgeons who wore clear masks were perceived by patients to be better communicators, have more empathy, and elicit greater trust https://t.co/xmbbWqZaTL @IanKratzkeMD @muneerakapadia @UNCSurgery

— JAMA Surgery (@JAMASurgery) March 12, 2021

NICE publishes single guideline for managing COVID-19

24 Mar, 2021 | 08:42h | UTC

NICE publishes single guideline for managing COVID-19 – National Institute for Health and Care Excellence

News release: COVID-19 rapid guideline: managing COVID-19 – National Institute for Health and Care Excellence

Commentary on Twitter

Today NICE has published a single guideline for managing COVID-19, which brings together content from previous rapid COVID-19 guidance and evidence summaries. Read more: https://t.co/3O5yzpHK9e pic.twitter.com/DyD7lcLX8v

— NICE (@NICEComms) March 23, 2021

Preventing the next pandemic: the power of a global viral surveillance network

25 Mar, 2021 | 08:29h | UTC

Preventing the next pandemic: the power of a global viral surveillance network – The BMJ

A follow-up study shows that recovered patients with re-positive PCR test in Wuhan may not be infectious

25 Mar, 2021 | 08:24h | UTC

A follow-up study shows that recovered patients with re-positive PCR test in Wuhan may not be infectious – BMC Medicine

Covid-19: What do we know about Sputnik V and other Russian vaccines?

25 Mar, 2021 | 08:27h | UTC

Covid-19: What do we know about Sputnik V and other Russian vaccines? – The BMJ

RCT: Effect of continued weekly subcutaneous Semaglutide vs. placebo on weight loss maintenance in adults with overweight or obesity

24 Mar, 2021 | 08:05h | UTC

Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial – JAMA (free for a limited period)

Commentaries: Continuing Semaglutide Leads to Further Weight Loss – NEJM Journal Watch AND STEP 4: Long-term treatment needed for full semaglutide benefit – MedwireNews

Podcast: Semaglutide for Weight Loss – JAMA

Commentary on Twitter

In this RCT, weekly subcutaneous subcutaneous semaglutide resulted in increased weight loss over 48 weeks vs placebo in adults with #overweight or #obesity https://t.co/Ze6zHCG1Fd

— JAMA (@JAMA_current) March 23, 2021