Archives
[Preprint] Meta-analysis of risk of vaccine-induced immune thrombotic thrombocytopenia following ChAdOx1-S recombinant vaccine – Overall risk is 1 in 139,000; for age 65 and over, about 1 in 1,000,000; for age under 55, between 1 in 20,000 to 60,000.
12 May, 2021 | 08:45h | UTC
COVID-19 oxygen needs in low- and middle-income countries have tripled in just three months – where are solutions?
12 May, 2021 | 08:43h | UTC
Study shows BMI cut-offs for obesity and diabetes risk do not work for non-white populations.
12 May, 2021 | 08:41h | UTC
Guideline: SGLT-2 inhibitors or GLP-1 receptor agonists for adults with type 2 diabetes – This guidance recommends a risk-based approach, advising against starting SGLT-2 inhibitors or GLP-1 receptor agonists in patients with three or fewer cardiovascular risk factors and without established CVD or CKD.
12 May, 2021 | 08:42h | UTCEditorial: Newer drug treatments for type 2 diabetes
Commentary on Twitter
New guideline provides risk-stratified recommendations about when to add SGLT-2 inhibitors or GLP-1 receptor agonists to existing treatment for adults with type 2 diabetes.#BMJInfographic provides an overview of the recommendations @will_s_t https://t.co/G7267xadmH pic.twitter.com/vKGj5xlm4Y
— The BMJ (@bmj_latest) May 11, 2021
RCT: An internet-delivered cognitive behavioral therapy (CBT) program followed by in-person CBT if necessary is noninferior to in-person CBT for the treatment of obsessive-compulsive disorder symptoms in children and adolescents.
12 May, 2021 | 08:39h | UTCEffect of an Internet-Delivered Stepped-Care Program vs In-Person Cognitive Behavioral Therapy on Obsessive-Compulsive Disorder Symptoms in Children and Adolescents: A Randomized Clinical Trial – JAMA (free for a limited period)
News release: Online CBT effective against OCD symptoms in the young – Karolinska Institutet
Review: Diagnosis and management of headache.
12 May, 2021 | 08:36h | UTCDiagnosis and Management of Headache: A Review – JAMA (free for a limited period)
Audio clinical review: Diagnosis and Management of Headache, Part 1 – JAMA
RCT: Among adults with idiopathic pulmonary fibrosis, antimicrobial therapy with co-trimoxazole or doxycycline is not associated with improved outcomes.
12 May, 2021 | 08:37h | UTCEffect of Antimicrobial Therapy on Respiratory Hospitalization or Death in Adults With Idiopathic Pulmonary Fibrosis: The CleanUP-IPF Randomized Clinical Trial – JAMA (free for a limited period)
Commentary on Twitter
Among adults with idiopathic pulmonary fibrosis, addition of co-trimoxazole or doxycycline compared with usual care did not significantly improve the time to nonrespiratory hospitalization or death https://t.co/t6WQ2sifx0
— JAMA (@JAMA_current) May 11, 2021
Perspective | 12 things to do to improve wellbeing in the ICU.
12 May, 2021 | 08:30h | UTC12 Things to Do to Improve Wellbeing in the ICU – ICU Management & Practice
Perspective | Top five priorities for a new ICU director during the first year.
12 May, 2021 | 08:33h | UTCTop Five Priorities for a New ICU Director During the First Year – ICU Management & Practice
Review: Neurologic assessment of the neurocritical care patient.
12 May, 2021 | 08:24h | UTCNeurologic Assessment of the Neurocritical Care Patient – Frontiers in Neurology
Review: The incidence, risk, presentation, pathophysiology, treatment, and effects of perioperative acute kidney injury.
12 May, 2021 | 08:27h | UTC
Perspective | The essentials for a humanized ICU.
12 May, 2021 | 08:28h | UTCThe Essentials for a Humanised Intensive Care Unit (H-ICU) – ICU Management & Practice
Ten simple steps to improve ventilation in healthcare facilities
11 May, 2021 | 09:27h | UTCTen simple steps to improve ventilation in healthcare facilities – Essential Critical Care
Commentary on Twitter
I've written ten simple steps to improve ventilation in healthcare facilities… with no jargon and loads of photos.
With expert input from @akm5376 @vfmcneill & @kartc from @IndiaCOVIDSOS.
Download here: https://t.co/OzsDXfPavm#COVIDisAirborne pic.twitter.com/UtsRO0IgWr
— Bex Sierra (@Global_ICU) May 5, 2021
Just 2% of SARS-CoV-2−positive individuals carry 90% of the virus circulating in communities
11 May, 2021 | 09:31h | UTC
Commentary on Twitter
Covid-19 is a supercarrier story. (!)
90% of the virus load (circulating virions) is harbored by only 2% of individuals
[So much for the 80/20 Pareto principle]https://t.co/zidXh7DBjt@PNASNews by @Sara_Sawyer_ @CUBoulder @BioFrontiers and colleagues pic.twitter.com/xIPpgaGLTE— Eric Topol (@EricTopol) May 10, 2021
A global database of COVID-19 vaccinations
11 May, 2021 | 09:28h | UTCA global database of COVID-19 vaccinations – Nature Human Behaviour
See website: Statistics and Research: Coronavirus (COVID-19) Vaccinations – Our World in Data
Commentaries on Twitter
Since the beginning of the COVID vaccinations we brought together the global data.
It's the most cited resource that @OurWorldInData has ever produced. Thousands of citations every week.
Just now our vaccination dataset has been published in Nature!https://t.co/COmCMNSbw2
— Max Roser (@MaxCRoser) May 10, 2021
A stunner.
One of my favorite graphics from the pandemic: the story of the unprecedented #SARSCoV2 vaccines
Published today @NatureHumBehav @OurWorldInData https://t.co/raPq8H3DSq@redouad @MaxCRoser @_HannahRitchie @EOrtizOspina @lucasrodesg @lucasrodesg @JoeHasell @appel_cam pic.twitter.com/x1LYobAOkM— Eric Topol (@EricTopol) May 10, 2021
Mild COVID-19 infection is very unlikely to cause lasting heart damage
11 May, 2021 | 09:23h | UTCMild COVID-19 infection is very unlikely to cause lasting heart damage – Imperial College London
Commentary on Twitter
Mild Covid infection is unlikely to cause lasting heart damage, according to a study led by University College London. It's the largest & most detailed study to date into mild Covid infection and its longer-term impact on the heart https://t.co/pZ0Wgnf9zp pic.twitter.com/b1T9AClQeX
— delthia ricks 🔬 (@DelthiaRicks) May 9, 2021
Cohort study: Non-steroidal anti-inflammatory drug use is not associated with higher mortality or increased severity of COVID-19
11 May, 2021 | 09:25h | UTCCommentaries: Largest study to date confirms non-steroidal anti-inflammatory medications do not result in worse COVID-19 outcomes – The Lancet AND Non-steroidal anti-inflammatory drug use in COVID-19 – The Lancet Rheumatology AND Ibuprofen, other NSAIDs not tied to worse COVID illness, death – CIDRAP
Related study with similar findings: Nonsteroidal Antiinflammatory Drugs and Susceptibility to COVID‐19 – Arthritis & Rheumatism
Commentary on Twitter
NEW Research—Non-steroidal anti-inflammatory drugs (NSAIDs) do not increase the mortality or severity of #COVID19: findings from more than 72,000 people in the ISARIC @CCPUKstudy https://t.co/NPJzuS1wAx #LancetRheumatology #OpenAccess pic.twitter.com/LjG6O7e3F8
— The Lancet Rheumatology (@TheLancetRheum) May 7, 2021
Researchers tie severe immunosuppression to chronic COVID-19 and virus variants
11 May, 2021 | 09:21h | UTCResearchers Tie Severe Immunosuppression to Chronic COVID-19 and Virus Variants – JAMA
The myriad ways sewage surveillance is helping fight COVID around the world
11 May, 2021 | 09:19h | UTCThe myriad ways sewage surveillance is helping fight COVID around the world – Nature
A ‘more rapidly spreading virus’ (B.1.617 variant) is fueling India’s mega COVID-19 surge, WHO chief scientist says
11 May, 2021 | 09:16h | UTCSee also: WHO Upgrades Virus Mutation Driving India’s COVID Surge To ‘Variant of Concern’ – Global Cases Start To ‘Plateau’ – Health Policy Watch AND Why India needs oxygen more urgently than vaccines – Vox AND WHO names B1617 fourth COVID-19 variant of concern – CIDRAP
Analysis: Covid-19: How will a waiver on vaccine patents affect global supply?
11 May, 2021 | 09:17h | UTCCovid-19: How will a waiver on vaccine patents affect global supply? – The BMJ
Related Podcast: Coronapod: Waiving vaccine patents and coronavirus genome data disputes – Nature
M-A: Metabolic–bariatric surgery is associated with increased long-term survival in adults with obesity, the effects being more pronounced for people with pre-existing diabetes
11 May, 2021 | 09:11h | UTCAssociation of metabolic–bariatric surgery with long-term survival in adults with and without diabetes: a one-stage meta-analysis of matched cohort and prospective controlled studies with 174 772 participants – The Lancet (link to abstract – $ for full-text)
Mucormycosis: The ‘black fungus’ maiming Covid patients in India
11 May, 2021 | 09:14h | UTCMucormycosis: The ‘black fungus’ maiming Covid patients in India – BBC
See also: Potentially fatal ‘black fungus’ infections on the rise in India’s COVID-19 patients – LiveScience AND A potentially fatal fungal infection is cropping up among India’s Covid patients. – The New York Times AND WHO says virus strain in India a ‘variant of concern’ as Europe eases curbs – MedicalXpress
Commentary on Twitter (thread – click for more)
Doctors in India are concerned about an increase in a highly fatal fungal infection affecting cases & recently recovered from #COVID19. Mucormycosis, is a mold that attacks the respiratory tract, potentially eroding facial structures & harming the brain.🧵https://t.co/1rHU2nM346
— Eric Feigl-Ding (@DrEricDing) May 10, 2021
Population-based cohort study: Youngest children in class are more likely to be diagnosed with a learning disability
11 May, 2021 | 09:08h | UTCCommentary: Youngest children in class are more likely to be diagnosed with a learning disability – University of Turku
Observational study suggests an early head‐to‐pelvis computed tomography can expedite the diagnosis of potential causes in patients with out‐of‐hospital circulatory arrest without obvious etiology
11 May, 2021 | 09:10h | UTCEarly head‐to‐pelvis computed tomography in out‐of‐hospital circulatory arrest without obvious etiology – Academic Emergency Medicine (link to abstract – $ for full-text)
Commentary: Early Head-to-Pelvis CT for OHCA – Journal Feed