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Another study shows a single dose of an mRNA vaccine has maximal effects in those with past infection.
24 Jun, 2021 | 10:38h | UTCPrimary, Recall, and Decay Kinetics of SARS-CoV-2 Vaccine Antibody Responses – ACS Nano
Related: France recommends single dose of vaccine if previous Covid infection detected. AND [Preprint] More data showing a single-dose SARS-CoV-2 mRNA vaccine may be enough in individuals with previous COVID-19. AND Another study shows a single dose of mRNA vaccine may be enough for patients with previous Covid-19
Commentary on Twitter
Prior covid? Unless it's a severe case, one-dose mRNA vaccine adds considerable protection and nothing added by 2nd dose. This is now concordant w/ >20 studieshttps://t.co/8Qpuw193zk @acsnano pic.twitter.com/TJNbl8HPy9
— Eric Topol (@EricTopol) June 23, 2021
Effect of Vaccination on Household Transmission of SARS-CoV-2 in England – “the likelihood of household transmission was approximately 40 to 50% lower in households of index patients who had been vaccinated 21 days or more before testing positive than in households of unvaccinated index patients”.
24 Jun, 2021 | 09:52h | UTCRelated: Study in England showed one dose of COVID-19 vaccine can cut household transmission by up to half – This protection is on top of the reduced risk of a vaccinated person developing symptomatic infection, which is around 60 to 65% after the first dose AND Covid-19 vaccination prevents transmission from vaccinated to unvaccinated household members.
Report: SARS-CoV-2 variants and vaccines.
24 Jun, 2021 | 10:33h | UTCSARS-CoV-2 Variants and Vaccines – New England Journal of Medicine
Perspective | Delta variant triggers dangerous new phase in the pandemic.
24 Jun, 2021 | 10:43h | UTCDelta variant triggers dangerous new phase in the pandemic – Science
Analysis | Future of covid-19 vaccine pricing: lessons from influenza – “Routine use of covid-19 vaccines could strain health budgets if pricing follows the pattern seen with influenza vaccines”.
24 Jun, 2021 | 09:50h | UTCFuture of covid-19 vaccine pricing: lessons from influenza – The BMJ
Commentary on Twitter
https://twitter.com/hildabast/status/1407469629459468289
CDC: mRNA vaccines are likely linked to cases of myocarditis and pericarditis – 1,226 cases of myocarditis or pericarditis have been reported mostly in people under 30.
24 Jun, 2021 | 09:51h | UTCSee also: Experts: mRNA COVID-19 vaccines likely tied to heart inflammation – CIDRAP
Related: Case series: 7 cases of myocarditis following mRNA-based COVID-19 vaccination. AND Case series: clinical and cardiac magnetic resonance imaging findings of 4 cases of myocarditis following mRNA-based COVID-19 vaccination. AND Case series: symptomatic acute myocarditis in 7 adolescents following mRNA COVID-19 vaccination. AND CDC says heart inflammation cases were higher than expected in 16- to 24-year-olds after second Covid vaccine shot, but still rare. AND Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men. AND CDC is investigating several reports that teenagers and young adults may have developed myocarditis after receiving mRNA vaccines. Most cases were mild, more often in males than females, more often following dose 2 than dose 1, and typically, within 4 days after vaccination.
Review | My Treatment Approach to Clostridioides difficile Infection.
24 Jun, 2021 | 09:47h | UTCMy Treatment Approach to Clostridioides difficile Infection – Mayo Clinic Proceedings
Recommendations for the management of incidental pancreatic findings in adults.
24 Jun, 2021 | 09:48h | UTCRelated: Diagnosis and Surveillance of Incidental Pancreatic Cystic Lesions: 2017 Consensus Recommendations of the Korean Society of Abdominal Radiology – Korean Journal of Radiology AND Cohort Study: Incidence, Prevalence and 5-year Pancreatic-related Mortality of Pancreatic Cysts AND Meta-Analysis: Incidental Findings on MRI of Apparently Asymptomatic Adults AND Prevalence and outcomes of incidental imaging findings: umbrella review AND Incidental anarchy – The BMJ Opinion
Opinion | A strategy to reduce the carbon footprint of clinical trials.
24 Jun, 2021 | 09:45h | UTCA strategy to reduce the carbon footprint of clinical trials – The Lancet
Viewpoint | Progress in Pharmacotherapy for Obesity.
24 Jun, 2021 | 09:46h | UTCProgress in Pharmacotherapy for Obesity – JAMA (free for a limited period)
See also: Semaglutide’s Success Could Usher in a “New Dawn” for Obesity Treatment – JAMA (free for a limited period)
Audio clinical review: Semaglutide for Weight Loss
Youth running consensus statement: minimizing risk of injury and illness in youth runners.
24 Jun, 2021 | 09:42h | UTC
Systematic review: low‐dose oral misoprostol probably has many benefits over other methods for labor induction.
24 Jun, 2021 | 09:44h | UTCLow‐dose oral misoprostol for induction of labour – Cochrane Library
RCT: Lutetium-177–PSMA-617 for metastatic castration-resistant prostate cancer.
24 Jun, 2021 | 09:41h | UTCLutetium-177–PSMA-617 for Metastatic Castration-Resistant Prostate Cancer – New England Journal of Medicine (link to abstract – $ for full-text)
[News release – not published yet] COVID-19 outpatient thrombosis prevention trial ends early – “Results suggest that not treating certain symptomatic but stable outpatients with anticoagulant or antiplatelet therapy may be the best course of action”.
23 Jun, 2021 | 10:32h | UTCCommentary: Antithrombotics No Help for Stable COVID-19 Outpatients: ACTIV-4b – TCTMD
Interactive Infographic | Interpreting a lateral flow SARS-CoV-2 antigen test – “This calculator demonstrates how interpreting a covid-19 lateral flow device (LFD) result varies according to the pre-test probability, and the sensitivity and specificity of the LFD used”.
23 Jun, 2021 | 10:29h | UTCInterpreting a lateral flow SARS-CoV-2 antigen test – The BMJ
Laboratory testing for suspected COVID-19 vaccine–induced (immune) thrombotic thrombocytopenia.
23 Jun, 2021 | 10:25h | UTC
Delta coronavirus variant: scientists brace for impact.
23 Jun, 2021 | 10:27h | UTCDelta coronavirus variant: scientists brace for impact – Nature
New Analysis reveals link between birthdays and COVID-19 spread during the height of the pandemic.
23 Jun, 2021 | 10:22h | UTCNews release: New Analysis reveals link between birthdays and COVID-19 spread during the height of the pandemic – Harvard Medical School
Original Study: Assessing the Association Between Social Gatherings and COVID-19 Risk Using Birthdays – JAMA Internal Medicine
Commentary on Twitter (thread – click for more)
The link between birthdays and Covid-19
Thread on our new study (w/ @CM_Whaley, Jon Cantor, Megan Pera) in @JAMAInternalMed
Using data on ~3M households, households in which a member had bday 2 wks prior were ~30% more likely to have a covid diagnosishttps://t.co/KHCvGAlvox
— Anupam Jena (@AnupamBJena) June 21, 2021
UNESCO and WHO urge countries to make every school a health-promoting school.
23 Jun, 2021 | 10:18h | UTCNews release: UNESCO and WHO urge countries to make every school a health-promoting school – World Health Organization
Guideline: WHO guideline on school health services – World Health Organization
Commentary: UNESCO and WHO Launch Initiative to Promote Healthier School Environments – Health Policy Watch
Commentary on Twitter (thread – click for more)
WHO and @UNESCO urge countries to make every school a health-promoting school, following the Global Standards for Health-promoting Schools that aim to ensure all schools promote life skills, cognitive & socioemotional skills & healthy lifestyles.https://t.co/qnMB3EprR8
— World Health Organization (WHO) (@WHO) June 22, 2021
The Risk of Allergic Reaction to SARS-CoV-2 Vaccines and Recommended Evaluation and Management: A Systematic Review, Meta-analysis, GRADE Assessment, and International Consensus Approach.
23 Jun, 2021 | 10:23h | UTC
AHA Scientific Statement: Obstructive Sleep Apnea and Cardiovascular Disease.
23 Jun, 2021 | 10:16h | UTCNews Release: Sleep apnea worsens heart disease, yet often untreated – American Heart Association
Cohort study: no association was found between statin therapy and cognitive decline or incident dementia in older adults.
23 Jun, 2021 | 10:14h | UTCCommentaries: Statin Therapy Not Associated With Cognitive Decline, Dementia in Older Adults, Study Says – American College of Cardiology AND Effect of Statins on Cognitive Decline and Dementia in Older Adults – American College of Cardiology
Review: Transcatheter treatment of valvular heart disease.
23 Jun, 2021 | 10:12h | UTCTranscatheter Treatment of Valvular Heart Disease: A Review – JAMA
Audio Clinical Review: Transcatheter Treatments of Valvular Heart Disease
Video: Transcatheter Aortic Valve Implantation (TAVI)
Video: Transcatheter Aortic Valve-in-Valve Procedure After Bioprosthetic Valve Failure
Video: Transcatheter Mitral Valve-in-Valve Procedure After Bioprosthetic Valve Failure
Video: Mitral Valve Transcatheter Edge-to-Edge Repair
Expert analysis | The global prevention of cardiovascular disease among people living with diabetes: leading with heart.
23 Jun, 2021 | 10:13h | UTCOriginal publication and resources: The Global Diabetes Compact – World Health Organization
See also: The WHO Global Diabetes Compact: a new initiative to support people living with diabetes – The Lancet Diabetes & Endocrinology (free registration required)
[Preprint] Rapid displacement of SARS-CoV-2 variant B.1.1.7 (Alpha) by B.1.617.2 (Delta) and P.1 (Gamma) in the United States.
22 Jun, 2021 | 10:12h | UTCRapid displacement of SARS-CoV-2 variant B.1.1.7 by B.1.617.2 and P.1 in the United States – medRxiv
Commentary on Twitter
🆕💥💥Preprint
📌B.1.617.2 Delta and P.1 are growing faster than B.1.1.7 & B.1.617.2 is growing faster than P.1 in the US
📌B.1.617.2 will soon be the dominant variant in the US
📌B.1.617.2 is growing more rapidly in counties with lower vaccination rateshttps://t.co/6Rf3p5N4ed pic.twitter.com/sVzyQRXn12— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) June 22, 2021