Archives
Pulmonary embolism in patients with COVID-19: incidence, risk factors, clinical characteristics, and outcome.
30 Jun, 2021 | 10:13h | UTC
Consensus Statement: The role of lung ultrasound in COVID-19 disease.
30 Jun, 2021 | 10:12h | UTCThe role of lung ultrasound in COVID-19 disease – Insights into Imaging
RCT: Among patients with diarrhea-predominant irritable bowel syndrome, a low FODMAP diet achieved earlier symptomatic improvements in stool frequency and excessive wind.
30 Jun, 2021 | 10:09h | UTC
Should I get my second AstraZeneca dose? Yes, it almost doubles your protection against Delta.
30 Jun, 2021 | 10:11h | UTCRelated: Effectiveness of COVID-19 vaccines against the B.1.617.2 variant – medRxiv
M-A: The utility of the rapid shallow breathing index in predicting successful extubation – “As a stand-alone test, the RSBI has moderate sensitivity and poor specificity for predicting extubation success”.
30 Jun, 2021 | 10:07h | UTCThe Utility of the Rapid Shallow Breathing Index in Predicting Successful Extubation: A Systematic Review and Meta-analysis – CHEST (link to abstract – $ for full-text)
Multidisciplinary guideline on Achilles tendinopathy.
30 Jun, 2021 | 10:06h | UTCDutch multidisciplinary guideline on Achilles tendinopathy – British Journal of Sports Medicine
M-A: SGLT2 inhibitors decrease cardiovascular death and heart failure hospitalizations in patients with heart failure.
30 Jun, 2021 | 10:08h | UTC
Review: Virtual consultation for red eye.
30 Jun, 2021 | 10:04h | UTCVirtual consultation for red eye – The BMJ
Commentary on Twitter
Red eye is a common ophthalmic presentation in primary care, accounting for 2 to 3% of the consultations.
How can you safely diagnose and manage patients with acute red eye(s) in a virtual consultation?https://t.co/cn12VYpyuW
— The BMJ (@bmj_latest) June 29, 2021
IHME COVID-19 model has been updated for over 200 world locations.
29 Jun, 2021 | 10:13h | UTCCOVID-19 Projections – Institute for Health Metrics and Evaluation
Video: Insights from IHME’s latest COVID-19 model update
Commentary on Twitter
📣 NEW ✨ Our COVID-19 model has been updated for over 200 world locations 🌎 🌍 🌏 📊 (https://t.co/5biAggRz1T)
📺 Full video: https://t.co/wLGeAiiYhy
📄 PDFs with explanations of country-specific projections: https://t.co/9KQxWwhQqx pic.twitter.com/8sSEzyXEf8— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) June 27, 2021
Review: Imaging of inflammatory disease of the pancreas.
30 Jun, 2021 | 10:03h | UTCImaging of inflammatory disease of the pancreas – British Journal of Radiology
Phase 1/2 RCT: CoronaVac is well tolerated and safe and induces strong humoral responses in children and adolescents aged 3–17 years.
29 Jun, 2021 | 10:09h | UTCInvited commentary: COVID-19 vaccines for children younger than 12 years: are we ready? – The Lancet Infectious Diseases
Commentary on Twitter
NEW—A phase 1/2 clinical trial of #CoronaVac in 550 children and adolescents aged 3-17 years in China suggests two doses of the vaccine are safe and generate a strong antibody response. Read in @TheLancetInfDis: https://t.co/eXSagRu1Cs pic.twitter.com/fOKNLUjNwc
— The Lancet (@TheLancet) June 28, 2021
SARS-CoV-2 mRNA vaccines induce persistent human germinal center responses, suggesting immunity will be long-lasting.
29 Jun, 2021 | 10:03h | UTCSARS-CoV-2 mRNA vaccines induce persistent human germinal centre responses – Nature
Commentaries: Immune response to FDA-approved vaccines is strong and potentially long-lasting – News Medical
Commentary on Twitter (thread – click for more)
Just published @nature
A bonus factor after covid vaccination: germinal center factories for durable, antigen-specific, B cells and plasmoblasts induced by mRNA vaccination, as determined by lymph node aspirates from vaccinees https://t.co/5eR0gDSWHq
@TheBcellArtist @WUSTLmed pic.twitter.com/C5xPSrh5Gw— Eric Topol (@EricTopol) June 28, 2021
Case report: Thrombosis with Thrombocytopenia After the Messenger RNA–1273 Vaccine.
29 Jun, 2021 | 10:07h | UTCThrombosis With Thrombocytopenia After the Messenger RNA–1273 Vaccine – Annals of Internal Medicine
[Preprint] 3rd AstraZeneca shot gives strong immunity.
29 Jun, 2021 | 10:01h | UTCStudy: 3rd AstraZeneca shot gives strong immunity – Reuters
Original Study (preprint): Tolerability and Immunogenicity After a Late Second Dose or a Third Dose of ChAdOx1 nCoV-19 (AZD1222) – SSRN/The Lancet
Ivermectin for the treatment of COVID-19: A systematic review and meta-analysis of randomized controlled trials – “IVM did not reduce all-cause mortality, length of stay or viral clearance in RCTs in COVID-19 patients with mostly mild disease”.
29 Jun, 2021 | 10:00h | UTC
WHO issues first global report on Artificial Intelligence (AI) in health and six guiding principles for its design and use.
29 Jun, 2021 | 09:56h | UTCGuidance: Ethics and governance of artificial intelligence for health – World Health Organization
Commentary: Artificial Intelligence ‘Very Promising’ for Health, Says WHO – Health Policy Watch
Commentary on Twitter (thread – click for more)
Artificial Intelligence (#AI) holds enormous potential for improving the health of millions of people around 🌎🌍🌏, but only if ethics & human rights are put at the heart of its design, deployment, & use.
More in WHO’s first global report on AI & Health👉https://t.co/fC7SX51YzY pic.twitter.com/1Jp0ASPDY3
— World Health Organization (WHO) (@WHO) June 28, 2021
The COVID pandemic’s lingering impact on clinical trials – “Medical researchers are beginning to shift their focus away from COVID-19 — but the pandemic could continue to affect studies focused on other diseases.”
29 Jun, 2021 | 09:57h | UTCThe COVID pandemic’s lingering impact on clinical trials – Nature
Systematic review: the evidence behind robot-assisted abdominopelvic surgery – “there is currently no clear advantage with existing robotic platforms, which are costly and increase operative duration”.
29 Jun, 2021 | 09:55h | UTCThe Evidence Behind Robot-Assisted Abdominopelvic Surgery: A Systematic Review – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentary: Robotic Platforms Not Superior for Abdominopelvic Surgery – HealthDay
Podcast | Evaluation and management of hypercalcemia.
29 Jun, 2021 | 09:51h | UTC#281 Hypercalcemia: Calci-fun! with Dr. Carl Pallais – The Curbsiders
EBM Analysis | Does tranexamic acid work for everything? For anything?
29 Jun, 2021 | 09:53h | UTCDoes TXA work for everything? For anything? – First10EM
Phase 2 RCT: Immunogenicity and reactogenicity of a Pfizer-BioNTech booster in patients that have received a single dose of AstraZeneca vaccine – “BNT162b2 (Pfizer) given as a second dose in individuals prime vaccinated with ChAdOx1-S (AstraZeneca) induced a robust immune response, with an acceptable and manageable reactogenicity profile”.
28 Jun, 2021 | 10:01h | UTCCommentaries: Heterologous vaccine regimens against COVID-19 – The Lancet AND
Commentary on Twitter (thread – click for more)
NEW #COVID19 research—Phase 2 trial by @borobia_am, @antoniojcarcas
et al. reports BNT162b2 given as a 2nd dose in individuals prime vaccinated with ChAdOx1-S induced a robust immune response, with an acceptable and manageable reactogenicity profile. Read https://t.co/muL0XQxdjG. pic.twitter.com/BxPlXB8EF7— The Lancet (@TheLancet) June 26, 2021
WHO urges fully vaccinated people to continue to wear masks as delta Covid variant spreads.
28 Jun, 2021 | 09:55h | UTCWHO urges fully vaccinated people to continue to wear masks as delta Covid variant spreads – CNBC
Commentary on Twitter (thread – click for more)
⚠️WEAR MASK EVEN IF VACCINATED—Top @WHO leader urges masks against #DeltaVariant even if 2-dose vaxxed. "Vaccine alone won't stop community transmission. People need to use masks consistently, be in ventilated spaces—even if you're vaccinated" #COVID19🧵https://t.co/qPZTmcy9iW pic.twitter.com/j5V6fbHdoi
— Eric Feigl-Ding (@DrEricDing) June 26, 2021
RCT: Similar outcomes with mycophenolate mofetil vs. azathioprine in kidney transplant recipients on steroid-free, low-dose cyclosporine immunosuppression.
29 Jun, 2021 | 09:50h | UTC
Delta “Plus”: Scientists say too early to tell risk of Covid-19 variant.
28 Jun, 2021 | 09:53h | UTCDelta plus India: Scientists say too early to tell risk of Covid-19 variant – BBC
Perspective | Is one vaccine dose enough if you’ve had COVID? What the science says.
28 Jun, 2021 | 09:52h | UTCIs one vaccine dose enough if you’ve had COVID? What the science says – Nature
Commentary on Twitter
One vaccine dose for prior covid: @ElieDolgin reviews the recent data @Nature https://t.co/amJ4RcGtuW
Vaccination cards/proof should be modified here to equate prior covid as the 1st dose and not force people to get an unnecessary 2nd dose— Eric Topol (@EricTopol) June 27, 2021