Open access
Open access
Powered by Google Translator Translator

Archives

2021 Update in the diagnosis and management of acute coronary syndromes for the perioperative clinician.

3 Aug, 2021 | 02:22h | UTC

2021 Update in the Diagnosis and Management of Acute Coronary Syndromes For the Perioperative Clinician – Journal of Cardiothoracic and Vascular Anesthesia

 

Commentary on Twitter

https://twitter.com/AlejandroLemor/status/1418925354870349826

 

RCT: Pimavanserin in dementia-related psychosis.

3 Aug, 2021 | 02:06h | UTC

Trial of Pimavanserin in Dementia-Related Psychosis – New England Journal of Medicine

 

M-A: Effects of experimental interventions to improve the peer‐review process – “Modifications of the traditional peer‐review process at reviewer‐level are associated with improved quality, at the price of longer duration.”

3 Aug, 2021 | 02:09h | UTC

Effects of Experimental Interventions to Improve the Biomedical Peer‐Review Process: A Systematic Review and Meta‐Analysis – Journal of the American Heart Association

Editorial: Reviewing Peer Review

 

RCT: First-line nivolumab plus chemotherapy vs. chemotherapy alone for advanced gastric, gastro-esophageal junction, and esophageal adenocarcinoma.

3 Aug, 2021 | 02:02h | UTC

First-line nivolumab plus chemotherapy versus chemotherapy alone for advanced gastric, gastro-oesophageal junction, and oesophageal adenocarcinoma (CheckMate 649): a randomised, open-label, phase 3 trial – The Lancet (link to abstract – $ for full-text)

 

Commentary on Twitter (thread – click for more)

 

How to safely dispose of medication.

3 Aug, 2021 | 01:55h | UTC

How to safely dispose of medication – Medical News Today

 

Opinion | Should pregnant women have a COVID vaccine? The evidence says it’s safe and effective.

2 Aug, 2021 | 00:28h | UTC

Should pregnant women have a COVID vaccine? The evidence says it’s safe and effective – The Conversation

 

Subgroup analysis of RCT suggests early rhythm control therapy is beneficial for patients with atrial fibrillation and heart failure.

3 Aug, 2021 | 02:00h | UTC

Early Rhythm Control Therapy in Patients with Atrial Fibrillation and Heart Failure – Circulation

Original study: #ESCCongress – [Abstract Only] Randomized trial: Early rhythm-control therapy in patients with atrial fibrillation (study and commentaries)

Related:

Meta-Analysis: Catheter Ablation Improves Outcomes in Patients with Atrial Fibrillation Complicated with Heart Failure

Catheter Ablation for Atrial Fibrillation Improves Outcomes in Heart Failure with Reduced Ejection Fraction

M-A: In patients with atrial fibrillation, catheter ablation was associated with a 38% reduction in recurrence and a 68% reduction in hospitalizations. The rate of serious complications was 4.2% with ablation vs. 2.8% in the antiarrhythmic group, a difference that was not statistically significant.

CABANATrial: Catheter Ablation vs Antiarrhythmic Drug Therapy on Mortality, Stroke, Bleeding, and Cardiac Arrest Among Patients With Atrial Fibrillation

 

The study behind new CDC’s mask guidance found vaccinated people can spread delta variant.

2 Aug, 2021 | 00:33h | UTC

CDC Report: Outbreak of SARS-CoV-2 Infections, Including COVID-19 Vaccine Breakthrough Infections, Associated with Large Public Gatherings — Barnstable County, Massachusetts, July 2021 – Centers for Disease Control and Prevention

Commentaries:

The Study Behind CDC’s Mask Guidance Found Vaccinated People Can Spread Delta Variant – NPR

What Delta has changed in the Covid pandemic — and what it hasn’t – STAT

 

Commentary on Twitter (thread – click for more)

 

Guideline: Clinical management of adult patients with COVID-19 Outside Intensive Care Units.

2 Aug, 2021 | 00:26h | UTC

Clinical Management of Adult Patients with COVID-19 Outside Intensive Care Units: Guidelines from the Italian Society of Anti-Infective Therapy (SITA) and the Italian Society of Pulmonology (SIP) – Infectious Diseases and Therapy

 

How the coronavirus infects cells — and why Delta is so dangerous.

2 Aug, 2021 | 00:22h | UTC

How the coronavirus infects cells — and why Delta is so dangerous – Nature

 

ACOG and SMFM Recommend COVID-19 Vaccination for Pregnant Individuals – “ACOG encourages its members to enthusiastically recommend vaccination to their patients.”

2 Aug, 2021 | 00:31h | UTC

ACOG and SMFM Recommend COVID-19 Vaccination for Pregnant Individuals – American College of Obstetricians and Gynecologists (ACOG) and the Society for Maternal-Fetal Medicine (SMFM)

Additional reading:

Practice Advisory: COVID-19 Vaccination Considerations for Obstetric-Gynecologic Care

COVID-19 Vaccines and Pregnancy: Conversation Guide for Clinicians

Commentaries:

Obstetrician groups recommend COVID vaccine during pregnancy – Associated Press

Statements By Obstetrics Societies Strongly Advise Covid-19 Vaccinations For Pregnant Women – Forbes

 

Commentary on Twitter

 

Post-viral effects of COVID-19 in the olfactory system and their implications.

2 Aug, 2021 | 00:24h | UTC

Post-viral effects of COVID-19 in the olfactory system and their implications – The Lancet Neurology

Related:

Study finds 96.1% of patients objectively recovered from anosmia 1 year after COVID-19 diagnosis.

Eight out of ten people hospitalized with COVID-19 develop neurological problems – the most common self-reported symptoms included headache (37%) and anosmia or ageusia (26%).

Loss of smell in mild Covid-19 cases occurs 86% of the time, study says

Management of anosmia and loss of smell in the era of Covid-19

 

What every intensivist should know about Tocilizumab.

2 Aug, 2021 | 00:25h | UTC

What every intensivist should know about Tocilizumab – Critical Care

Related:

Tocilizumab in COVID-19 therapy: who benefits, and how?

A living WHO guideline on drugs for covid-19 – interleukin-6 receptor blockers are now recommended for patients with severe or critical covid-19.

M-A: Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19 – “The 4% absolute risk reduction in mortality from 25% to 21% with IL-6 inhibition added to glucocorticoids may not translate to patients with a lower baseline mortality risk and likely do not justify the additional expense and risk for toxicities for patients hospitalized with modest oxygen requirements and a stable clinical course (from editorial)”.

RECOVERY trial: In hospitalized COVID-19 patients with hypoxia and systemic inflammation (C-reactive protein ≥75 mg/L), tocilizumab improved survival and other clinical outcomes

Secondary analysis of RCT finds Tocilizumab was beneficial to patients hospitalized with Covid-19 if CRP levels were greater than 15.0 mg/dL, but not if CRP levels were 15.0 mg/dL or less.

M-A: Tocilizumab in COVID-19 – “For hospitalized COVID-19 patients, there is some evidence that tocilizumab use may be associated with a short-term mortality benefit, but further high-quality data are required”.

 

COVID boosters for wealthy nations spark outrage.

2 Aug, 2021 | 00:21h | UTC

COVID boosters for wealthy nations spark outrage – Nature

Related: MSF: No COVID-19 booster shots anywhere before healthcare workers and vulnerable people everywhere have access – Médecins Sans Frontières/Doctors Without Borders

 

Clinical practice guidelines for the management of colonic volvulus and acute colonic pseudo-obstruction.

2 Aug, 2021 | 00:13h | UTC

The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Management of Colonic Volvulus and Acute Colonic Pseudo-Obstruction – Diseases of the Colon & Rectum

News release: American Society of Colon & Rectal Surgeons Publishes New Guidelines for Colonic Volvulus and Acute Colonic Pseudo-Obstruction

 

Scientists Grapple with Question of COVID-19 Vaccine Booster, as Some Countries Push Ahead.

2 Aug, 2021 | 00:19h | UTC

Scientists Grapple With Question of COVID-19 Vaccine Booster, as Some Countries Push Ahead – Health Policy Watch

 

Ten things to know about ten imaging studies: A preventive cardiology perspective.

2 Aug, 2021 | 00:12h | UTC

Ten things to know about ten imaging studies: A preventive cardiology perspective (“ASPC top ten imaging”) – American Journal of Preventive Cardiology

 

AHA Scientific Statement: Lower extremity peripheral artery disease: contemporary epidemiology, management gaps, and future directions.

2 Aug, 2021 | 00:17h | UTC

Lower Extremity Peripheral Artery Disease: Contemporary Epidemiology, Management Gaps, and Future Directions: A Scientific Statement From the American Heart Association – Circulation

Top Things to Know: Lower Extremity Peripheral Artery Disease: Contemporary Epidemiology, Management Gaps, and Future Directions – American Heart Association

Commentary: The Need for Improved Identification and Treatment of Peripheral Arterial Disease – American Heart Association

 

Assessment and management of peripheral arterial disease: what every cardiologist should know.

2 Aug, 2021 | 00:15h | UTC

Assessment and management of peripheral arterial disease: what every cardiologist should know – Heart

 

Commentary on Twitter

https://twitter.com/Heart_BMJ/status/1417391335246553094

 

Ten things to know about ten cardiovascular disease risk factors.

2 Aug, 2021 | 00:11h | UTC

Ten things to know about ten cardiovascular disease risk factors – American Journal of Preventive Cardiology

 

Study: many patients with small renal masses can be safely managed with active surveillance.

2 Aug, 2021 | 00:07h | UTC

Active Surveillance for Risk Stratification of All Small Renal Masses Lacking Predefined Clinical Criteria for Intervention – The Journal of Urology

Commentary: More Data Support Active Surveillance for Small Renal Masses — Most patients avoided surgery with no metastasis, better focus on aggressive disease – MedPage Today (free registration required)

 

Investigation: FDA allows drugs without proven clinical benefit to languish for years on accelerated pathway.

2 Aug, 2021 | 00:09h | UTC

FDA allows drugs without proven clinical benefit to languish for years on accelerated pathway – The BMJ

News release: Investigation finds nearly half of drugs granted FDA ‘fast track’ approval lack proven clinical benefit – The BMJ

Commentary: Over 100 Drugs Given Speedy Approvals Still Lack Proof of Clinical Efficacy – MedPage Today (free registration required)

 

Guideline summary: A Multidisciplinary collaborative approach to retinal toxic effects screening for patients taking antimalarials.

2 Aug, 2021 | 00:03h | UTC

A Multidisciplinary Collaborative Approach to Retinal Toxic Effects Screening for Dermatology Patients Taking Antimalarials – JAMA Dermatology (free for a limited period)

Original Guidance: Joint Statement: Hydroxychloroquine use with respect to retinal toxicity

 

Does this adult patient have hypertension? the rational clinical examination systematic review.

2 Aug, 2021 | 00:05h | UTC

Does This Adult Patient Have Hypertension? The Rational Clinical Examination Systematic Review – JAMA (free for a limited period)

 

European PanCare Follow Up Recommendations for surveillance of late effects of childhood, adolescent, and young adult cancer.

1 Aug, 2021 | 23:59h | UTC

European PanCare Follow Up Recommendations for surveillance of late effects of childhood, adolescent, and young adult cancer – European Journal of Cancer

 

Stay Updated in Your Specialty

Telegram Channels
Free

WhatsApp alerts 10-day free trial

No spam, just news.