Archives
[Preprint] Full vaccination suppresses SARS-CoV-2 delta variant mutation frequency.
17 Aug, 2021 | 08:59h | UTCFull vaccination suppresses SARS-CoV-2 delta variant mutation frequency – medRxiv
Commentary: Research debunks myth that COVID vaccination promotes mutations – News Medical
Commentary on Twitter
Evidence that vaccinations successfully suppress viral mutations and that the unvaccinated are the source of the variants. https://t.co/U80T4JLO7A
"No one is safe until everyone is safe." pic.twitter.com/B2pVeMm96r— Daniel Griffin MD PhD (@DanielGriffinMD) August 15, 2021
Top antimicrobial stewardship intervention publications in 2020.
17 Aug, 2021 | 08:51h | UTC
Accuracy of novel antigen rapid diagnostics for SARS-CoV-2: A living systematic review and meta-analysis.
17 Aug, 2021 | 09:02h | UTC
COVID-19 long haulers – “With the risks of drug development prohibitive, repurposed or repositioned medicines appear the best hope against long-COVID, a condition that still raises many unanswered questions”.
17 Aug, 2021 | 08:57h | UTCCOVID-19 long haulers – Nature Biotechnology
Related: M-A: More than 50 long-term effects of COVID-19. (several articles on the subject)
Commentary on Twitter
A News Feature published in @NatureBiotech reports on how repurposed or repositioned medicines appear to be the best hope against long-COVID. https://t.co/Hc9s2tr8N8 pic.twitter.com/ue2sH4gWzT
— Nature Portfolio (@NaturePortfolio) August 16, 2021
Study finds editorialists in top journals with industry-related conflicts of interest were more likely to author an unduly favorable editorial for cancer drugs.
17 Aug, 2021 | 08:47h | UTC
RCT: Once-weekly tirzepatide vs. once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes.
17 Aug, 2021 | 08:50h | UTCOnce-weekly tirzepatide versus once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes (SURPASS-3): a randomised, open-label, parallel-group, phase 3 trial – The Lancet (link to abstract – $ for full-text)
Related:
RCT: New blood test could improve prostate cancer screening.
17 Aug, 2021 | 08:48h | UTCProstate cancer screening using a combination of risk-prediction, MRI, and targeted prostate biopsies (STHLM3-MRI): a prospective, population-based, randomised, open-label, non-inferiority trial – The Lancet Oncology (link to abstract – $ for full-text)
News release: New blood test improves prostate cancer screening – Karolinska Institutet
Related:
RCT: MRI can cut overdiagnoses in prostate-cancer screening by half.
Commentary on Twitter
Online first: #Prostatecancer #screening using a combination of risk-prediction, MRI, and targeted prostate biopsies (STHLM3-MRI): a prospective, population-based, randomised, open-label, non-inferiority trial #pcsm https://t.co/bijoJk8RbK pic.twitter.com/ENWEjqG3Kr
— The Lancet Oncology (@TheLancetOncol) August 13, 2021
P/FP ratio: incorporation of PEEP into the PaO2/FiO2 ratio for prognostication and classification of acute respiratory distress syndrome.
17 Aug, 2021 | 08:46h | UTC
Commentary on Twitter
P/FP ratio – This multifactorial P/FP ratio has a greater predictive validity for hospital mortality in ARDS than the P/F ratio. Changes in severity classification with the P/FP ratio reflect both true illness severity and the applied PEEP strategy.https://t.co/bsCm7ZFjIv pic.twitter.com/wwZZ0hhnlF
— Sunitha Palanidurai (@PFPratio) August 12, 2021
Scientific medical conferences can be easily modified to improve female inclusion: a prospective study.
17 Aug, 2021 | 08:53h | UTCAuthor Interview: Victoria Salem on improving female inclusion in conferences
Commentaries:
Women participate less at conferences, even with gender-balanced delegates – Imperial College London
Women participate less at conferences, even if gender-balanced – study – The Guardian
Commentaries on Twitter
🗣conference organisers take note: female chairs and picking first questions from females are easy modifications for scientific medical conferences to improve female inclusion https://t.co/pt722RB6E8
— A/Prof Sharleen O’Reilly (@OReillySharleen) August 5, 2021
"If women are not visible at conferences, they cannot act as role models…creating a self-perpetuating cycle."
How scientific medical conferences can be easily modified to improve female inclusion. Read in @TheLancetEndo—https://t.co/3vK5KCdqco #GenerationEquality pic.twitter.com/YPaqnlcCZo
— The Lancet (@TheLancet) July 30, 2021
https://twitter.com/WiebkeArlt/status/1420976987049537538
Cohort study: Early invasive coronary angiography in patients with acute ischemic heart failure is linked to better outcomes.
17 Aug, 2021 | 08:44h | UTCCommentary: Early Invasive Angiography in Acute Heart Failure – American College of Cardiology
Commentary on Twitter
Our new paper published in #EHJ @escardio! In acute HF with features suggestive of underlying CAD (prior MI, ⬆️trop, or angina), coronary angiography within 2 weeks of admission was associated with ⬇️mortality, CV death, and HF readmissions and ⬆️ revascularization at 2 years. https://t.co/q2cpV3mcMs
— Leah Kosyakovsky (@leahkosyakovsky) July 31, 2021
Review: Initial management of blunt and penetrating neck trauma.
17 Aug, 2021 | 08:40h | UTCInitial management of blunt and penetrating neck trauma – BJA Education
EM Cases: Testicular Torsion: A Diagnostic Pathway – “Time is Testes”.
17 Aug, 2021 | 08:41h | UTCEM Cases: Testicular Torsion: A Diagnostic Pathway – emDocs
Out of hospital cardiac arrest: Past, present, and future.
17 Aug, 2021 | 08:39h | UTCOut of hospital cardiac arrest: Past, present, and future – Resuscitation
Cohort study: Association of incomplete polyp removal with risk of postcolonoscopy colorectal cancer.
17 Aug, 2021 | 08:43h | UTCOriginal study: Recurrence of Colorectal Neoplastic Polyps After Incomplete Resection – Annals of Internal Medicine (link to abstract – $ for full-text)
FDA authorizes additional Covid-19 vaccine dose for certain immunocompromised individuals – Other fully vaccinated individuals do not need an additional vaccine dose right now.
16 Aug, 2021 | 01:22h | UTCCommentaries:
CDC, FDA recommend COVID booster for immune-compromised – CIDRAP
FDA authorizes additional dose of Covid-19 vaccine for the immunocompromised – STAT
Covid booster: US approves third jab for the immunocompromised – BBC
CDC Panel Recommends 3rd Vaccine Dose For Immunocompromised People – NPR
6 Things To Know If You’re Immunocompromised And Considering A 3rd Shot – NPR
CDC recommends third Covid-19 vaccine dose for certain immunocompromised people – CNN
Commentary on Twitter
The Infectious Diseases Society of America (IDSA) supports the @FDA and @CDCgov's decision to authorize a supplemental vaccine dose for immunocompromised patients.
Read our statement: https://t.co/odzzSgIxnY pic.twitter.com/4PZfUwpjhM
— IDSA (@IDSAInfo) August 13, 2021
Perspective: The high stakes of outsourcing in health care.
17 Aug, 2021 | 08:38h | UTCThe High Stakes of Outsourcing in Health Care – Mayo Clinic Proceedings
Perspective | Don’t panic, but breakthrough cases may be a bigger problem than you’ve been told.
16 Aug, 2021 | 01:17h | UTCDon’t Panic, But Breakthrough Cases May Be a Bigger Problem Than You’ve Been Told – Intelligencer
Commentary on Twitter (thread – click for more)
The vaccines are still performing quite well in preventing severe disease. But with Delta they are doing much worse in stopping transmission. Breakthroughs are probably now 10-20% of new infections, and perhaps as much as 5% of new deaths. A thread. (1/x) https://t.co/NvGends1ZP
— David Wallace-Wells (@dwallacewells) August 12, 2021
Benefits and risks of frequent or longer hemodialysis: weighing the evidence.
17 Aug, 2021 | 08:37h | UTC
CDC Guidance: Pregnant people should be vaccinated against COVID-19.
16 Aug, 2021 | 01:19h | UTCCOVID-19 Vaccines While Pregnant or Breastfeeding – Centers for Disease Control and Prevention
Related:
Opinion | Should pregnant women have a COVID vaccine? The evidence says it’s safe and effective.
[Preprint] Impact of the COVID-19 pandemic on early child cognitive development: initial findings in a longitudinal observational study of child health.
16 Aug, 2021 | 01:11h | UTC
Commentary on Twitter (thread – click for more)
Preprint on the development of children born before and during the pandemic in the US.
"We find that children born during the pandemic have significantly reduced verbal, motor, and overall cognitive performance compared to children born pre-pandemic."
1/https://t.co/NInexSUDAi— Prof Francois Balloux (@BallouxFrancois) August 15, 2021
Antibody responses after a single dose of AstraZeneca Covid-19 vaccine in previously infected individuals were similar or higher compared to antibody responses in SARS-CoV-2 naïve participants who received two doses of Pfizer mRNA vaccine.
16 Aug, 2021 | 01:15h | UTCCommentary (on the preprint): Single dose of Oxford-AstraZeneca vaccine protective in previously infected recipients, suggests study – News Medical
Related: More data showing one dose of Pfizer vaccine may be enough for individuals who’ve had COVID. (studies on the subject)
Durability of Moderna vaccine–induced antibodies against SARS-CoV-2 variants.
16 Aug, 2021 | 01:13h | UTCDurability of mRNA-1273 vaccine–induced antibodies against SARS-CoV-2 variants – Science
Commentary:
Moderna COVID-19 vaccine found to be still effective after six months – MedicalXpress
Moderna’s Covid-19 vaccine protects against Delta variant, study finds – CNN
Commentary on Twitter
The majority of individuals who received both doses of the mRNA-1273 (Moderna) vaccine maintained binding and functional antibodies against #SARSCoV2 variants for six months, a new Science study shows. https://t.co/jf98Rgasop pic.twitter.com/IN1cP33zxN
— Science Magazine (@ScienceMagazine) August 12, 2021
Bioethics | Should we tell stories of vaccine sceptics who have died of COVID?
16 Aug, 2021 | 01:06h | UTCShould we tell stories of vaccine sceptics who have died of COVID? – The Conversation
Opinion: “fear of covid-19 in kids is getting ahead of the data”.
16 Aug, 2021 | 01:09h | UTCFear of COVID-19 in Kids Is Getting Ahead of the Data – The Atlantic
Study suggests a potential protective benefit from MMR and TDP vaccines in reducing the risk of severe Covid-19 infections.
16 Aug, 2021 | 01:04h | UTC
Commentary on Twitter
New @MedCellPress
Prior Measles-Mumps-Rubella (MMR) or Tetanus-Diptheria-Pertussis (Tdap) vaccination induces a T-cell response that overlaps with #SARSCoV2 and appears to offer some (~20-30%) protection from severe Covid-19https://t.co/fYT7Qole8s pic.twitter.com/hMkHXvNQYU— Eric Topol (@EricTopol) August 14, 2021