Archives
Study commentary: How risky for developing psychosis are ‘At Risk Mental States’ in youths?
24 Aug, 2021 | 08:45h | UTCHow risky for developing psychosis are ‘At Risk Mental States’ in youths? – The Mental Elf
Original study: Systematic Review and Meta-analysis: Psychosis Risk in Children and Adolescents With an At-Risk Mental State – Journal of the American Academy of Child & Adolescent Psychiatry (link to abstract – $ for full-text)
Commentary on Twitter
Wouldn't it be great if we could identify teens at risk for psychosis & then prevent it?
Trouble is we can't- lit review shows that most "at risk" teens aren't really at risk/predictive tools don't predict accurately.
And the "At Risk" label can burden teens with stigma & meds. https://t.co/1SiBH5tQRz
— Allen Frances (@AllenFrancesMD) August 23, 2021
Review: Managing diabetic ketoacidosis in children.
24 Aug, 2021 | 08:46h | UTCManaging Diabetic Ketoacidosis in Children – Annals of Emergency Medicine
Review: A pragmatic approach to weaning temporary mechanical circulatory support.
24 Aug, 2021 | 08:47h | UTC
Commentary on Twitter
⚠️ A Pragmatic Approach to Weaning Temporary Mechanical Circulatory Support
📌 A State-of-the-Art Review ‼️ in @JACCJournals @secardiologia @AgudosSEC @SACardiologia @JuanFDelgado1 @Dr_Manito @MartaCoboMarcos @MartaFarrero https://t.co/R2vqHwBcfi pic.twitter.com/AraH7AUMu5
— Javier Torres (@JTLLERGO) August 11, 2021
Adult ADHD is linked to numerous physical conditions.
24 Aug, 2021 | 08:41h | UTCAdult ADHD is linked to numerous physical conditions – Karolinska Institutet
Commentaries on Twitter
Our new study in the Swedish population shows that ADHD leads to small by significant increases in the risk for many somatic disorders: https://t.co/SYTCntG9FD https://t.co/tLQ9qSxWWF
— Stephen Faraone (he/him/his) (@StephenFaraone) July 7, 2021
Important paper in @TheLancetPsych led by @EbbaDuRietz and @LarssonPsychEpi. We found that #ADHD in adults was associated with 34 out of 35 medical conditionshttps://t.co/K8xbokzZYx pic.twitter.com/Spw0ww98X0
— Samuele Cortese (@CorteseSamuele) July 6, 2021
Cluster RCT: Effects of a large-scale social media advertising campaign on holiday travel and COVID-19 infections.
23 Aug, 2021 | 00:01h | UTC
Commentary on Twitter
Even though we are tired, we should continue trying to educate the public through social media – “Social media messages recorded by health professionals before the winter holidays in the US led to a significant reduction in holiday travel and subsequent COVID-19 infections” https://t.co/kyeKTe4sJn
— gilberto lopes (@GlopesMd) August 22, 2021
M-A of randomized trials: Effectiveness of psychological interventions in prison to reduce recidivism.
24 Aug, 2021 | 08:42h | UTC
Commentary on Twitter
“Interventions that ensure continuity of care in community settings should be prioritised for future research.” https://t.co/FDIz1pbx7y
— ROBERTO COLOM (@ROBERTO_COLOM) August 20, 2021
Among patients receiving mRNA vaccines, clinically significant symptoms were more frequent following dose 2, following dose 1 in patients with previous SARS-CoV-2 infection, and in those who received the Moderna vaccine.
22 Aug, 2021 | 23:54h | UTC
Commentary on Twitter
New @JAMA_current paper says @moderna_Tx caused 2.3x the number of "significant" symptoms compared to @pfizer in a sample of 950 people.
Moderna also produced more antibodies. Raising the question of what a third dose, which produces still MORE, will do.https://t.co/drvhhsnpHo
— Alex Berenson (@AlexBerenson) August 16, 2021
RCT: A single-session of pain management skills intervention was noninferior to 8 sessions of cognitive behavioral therapy in adults with chronic low back pain.
24 Aug, 2021 | 08:39h | UTCCommentaries:
New approach effectively relieves chronic low back pain – Stanford Medicine
Commentary on Twitter
NEW STUDY: Our Empowered Relief trial just published!
A *single-session* pain relief skills class was non-inferior to 8-session CBT for pain & symptom reduction at 3 months post-treatmenthttps://t.co/HYmWNkxUoR via @JAMANetworkOpen part of @JAMANetwork
funded by @NIH_NCCIH
— Beth Darnall, PhD (@BethDarnall) August 16, 2021
[Preprint] Study shows symptomatic breakthrough infections are probably less transmissible than SARS-CoV-2 infections in unvaccinated individuals.
22 Aug, 2021 | 23:59h | UTC
Commentary on Twitter (thread – click for more)
Did you hear vaccinated people with Delta “have just as much virus in their nose so are just as infectious as unvaccinated”?
Turns out vaccinated people have significantly less culturable virus present at the same Ct count
They are LESS INFECTIOUS 💥 https://t.co/OX0Ul0ntWc pic.twitter.com/3vDQSJ6j84
— Alasdair Munro (@apsmunro) August 22, 2021
RCT: Awake prone positioning reduces the need for intubation in patients with COVID-19.
23 Aug, 2021 | 00:03h | UTCInvited commentary: Awake prone positioning in COVID-19: is tummy time ready for prime time?
Related:
Commentary on Twitter
Awake prone positioning of pts w/ hypoxaemic respiratory failure due to #COVID19 reduces incidence of treatment failure & need for intubation w/o any signal of harm
Meta-trial from the Awake Prone Positioning Meta-Trial Group https://t.co/GuDdjPnVps pic.twitter.com/ZS08uQN1gE
— The Lancet Respiratory Medicine (@LancetRespirMed) August 21, 2021
Evidence mounts that people with breakthrough infections can spread Delta easily.
22 Aug, 2021 | 23:57h | UTCOriginal study: Shedding of Infectious SARS-CoV-2 Despite Vaccination when the Delta Variant is Prevalent – Wisconsin, July 2021 – medRxiv
Commentary on Twitter
The evidence that supports Delta breakthrough infections ability to spread (and why fully vaccinated people need to 😷 up)https://t.co/27NOf6mYCM @NatGeo by @Ecquis w/ studies and input by @GuptaR_lab and @KasenRiemersma
— Eric Topol (@EricTopol) August 20, 2021
Lab study shows a heterologous AstraZeneca + Pfizer immunization strategy provides stronger immunogenicity against Covid compared to homologous AZ + AZ or Pfizer + Pfizer strategies.
22 Aug, 2021 | 23:51h | UTCInvited Commentary: Heterologous ChAdOx1-nCoV19–BNT162b2 vaccination provides superior immunogenicity against COVID-19
Related:
Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination (several articles on the subject)
Commentary on Twitter
NEW Research—Heterologous ChAdOx1 nCov-19–BNT162b2 immunisation w/ 10–12-week interval is well tolerated & improves immunogenicity vs homologous ChAdOx1 nCov-19 vax w/ 10–12-week interval & BNT162b2 vax w/ 3-week interval
Study from Prof Sander & co https://t.co/VAB54NokSi pic.twitter.com/wfeBsvoKhO
— The Lancet Respiratory Medicine (@LancetRespirMed) August 13, 2021
Study Commentaries: Non-invasive ventilation for COVID 19 patients. The Recovery RS trial.
22 Aug, 2021 | 23:52h | UTCCommentary 1: JC: Non-invasive ventilation for COVID 19 patients. The Recovery RS trial – St Emlyn’s
CoronaVac vaccine in older adults during a gamma variant associated epidemic of covid-19 in Brazil – Effectiveness against symptomatic disease was 46.8%, 55.5% against hospitalization, and 61.2% against deaths.
22 Aug, 2021 | 23:48h | UTCEditorial: Real world effectiveness of covid-19 vaccines
Related: CoronaVac vaccine: its results are patchy, but the world can’t ignore its usefulness. (several texts on the subject)
[Preprint] SARS-CoV-2 aerosol transmission in schools: theoretical effectiveness of different interventions – “Combined interventions (i.e., natural ventilation, masks, and HEPA filtration) were the most effective (≥ 30-fold decrease)”.
22 Aug, 2021 | 23:50h | UTCSARS-CoV-2 aerosol transmission in schools: the effectiveness of different interventions – medRxiv
Related: The right way to protect our children and return to in-person learning – CNN
Commentaries on Twitter
Interesting modelling study for schools: (theoretically) most effective is open windows, then masks, then HEPA filter. Would be good to do real world tests though. https://t.co/MDFNqNNUI3 pic.twitter.com/xGSodClipO
— Paul Glasziou (@PaulGlasziou) August 21, 2021
This is not real evidence supporting real policy choices as they are really carried out in the real world.
Instead, this is theoretical bioplausibility spun into a full paper.
I hope folks can still tell the two aparthttps://t.co/znwtiaKZ2g
— Vinay Prasad MD MPH (@VPrasadMDMPH) August 20, 2021
The Lancet Series: Heat and health.
22 Aug, 2021 | 23:04h | UTCHomepage: Heat and health
Editorial: Health in a world of extreme heat
Ollie Jay: managing heat, improving health
Hot weather and heat extremes: health risks
Observational data from Canada: Effectiveness of mRNA covid-19 vaccines was 91% against symptomatic disease and 98% against hospitalization and deaths.
22 Aug, 2021 | 23:47h | UTCEditorial: Real world effectiveness of covid-19 vaccines
ACOG Guideline: Osteoporosis prevention, screening, and diagnosis.
22 Aug, 2021 | 23:08h | UTC
NICE Guideline: Obstructive sleep apnea/hypopnea syndrome and obesity hypoventilation syndrome in over 16s.
22 Aug, 2021 | 23:10h | UTC
M-A: GLP-1 receptor agonists reduce major adverse cardiovascular events, all-cause mortality, hospital admission for heart failure, and worsening kidney function in patients with type 2 diabetes.
22 Aug, 2021 | 22:50h | UTCCardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of randomised trials – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Hot, Cold, and Deadly – Extreme temperature is a threat to global health.
22 Aug, 2021 | 23:01h | UTCHot, Cold, and Deadly – Think Global Health
Estimating the cause-specific relative risks of non-optimal temperature on daily mortality: a two-part modeling approach applied to the Global Burden of Disease Study.
22 Aug, 2021 | 23:02h | UTCRelated article: Mortality risk attributable to high and low ambient temperature: a multicountry observational study – The Lancet
Commentary on Twitter
📣 This #GBDstudy new in @TheLancet in is the first comprehensive global assessment of disease burden due to non-optimal temperature exposure. #ClimateChange #Research #GlobalHealth https://t.co/AUqTFHkTZL
— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) August 20, 2021
M-A: The role of SGLT2 inhibitors in heart failure.
22 Aug, 2021 | 22:46h | UTCRelated:
ESC Position Paper: Cardiac, renal, and metabolic effects of SGLT2 inhibitors.
Summary: SGLT2 inhibitors and GLP-1 receptor agonists established and emerging indications.
Why remote consultation with a doctor is difficult – and how it can be improved.
22 Aug, 2021 | 23:00h | UTCWhy remote consultation with a doctor is difficult – and how it can be improved – The Conversation
Original article: Planning and Evaluating Remote Consultation Services: A New Conceptual Framework Incorporating Complexity and Practical Ethics – Frontiers in Digital Health
Commentary on Twitter
https://twitter.com/trishgreenhalgh/status/1428664245357584390
Health researchers report funder pressure to suppress results – “Small study hints that interference from bodies funding research into public-health issues such as nutrition and exercise might be more common than realized”.
22 Aug, 2021 | 22:41h | UTCHealth researchers report funder pressure to suppress results – Nature
Original study: “He who pays the piper calls the tune”: Researcher experiences of funder suppression of health behaviour intervention trial findings – PLOS One