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RCT: Darolutamide and survival in metastatic, hormone-sensitive prostate cancer.

18 Feb, 2022 | 08:47h | UTC

Darolutamide and Survival in Metastatic, Hormone-Sensitive Prostate Cancer – New England Journal of Medicine

 

Commentary on Twitter

 


Guideline: Dietary changes to alleviate gastrointestinal symptoms.

18 Feb, 2022 | 08:38h | UTC

World Gastroenterology Organisation Global Guidelines: Diet and the Gut – Journal of Clinical Gastroenterology

 


NICE Updated Guidance: Diagnosis and Management of Glaucoma.

18 Feb, 2022 | 08:39h | UTC

Glaucoma: diagnosis and management – National Institute for Health and Care Excellence

 


Global, regional, and national prevalence estimates of physical or sexual, or both, intimate partner violence against women.

18 Feb, 2022 | 08:44h | UTC

Global, regional, and national prevalence estimates of physical or sexual, or both, intimate partner violence against women in 2018 – The Lancet

News release: More than a quarter of women have experienced intimate partner violence in their lifetimes, finds new study – The Lancet

Commentary: Intimate partner violence against women: a persistent and urgent challenge – The Lancet

 

Commentary on Twitter (thread – click for more)

 


Viewpoint: Achieving diagnostic excellence for older patients.

18 Feb, 2022 | 08:37h | UTC

Achieving Diagnostic Excellence for Older Patients – JAMA (free for a limited period)

 


VIP syndrome: why do the doctors to the stars make fatal mistakes?

18 Feb, 2022 | 08:33h | UTC

VIP syndrome: why do the doctors to the stars make fatal mistakes? – The Guardian

 


Arrhythmias in female patients: incidence, presentation and management.

18 Feb, 2022 | 08:31h | UTC

Arrhythmias in Female Patients: Incidence, Presentation and Management – Circulation Research (free for a limited period)

 


Open-access publishing fees deter researchers in the global south.

18 Feb, 2022 | 08:35h | UTC

Open-access publishing fees deter researchers in the global south – Nature

 


Bioterrorism: An analysis of biological agents used in terrorist events.

18 Feb, 2022 | 08:32h | UTC

Bioterrorism: An analysis of biological agents used in terrorist events – The American Journal of Emergency Medicine

 


M-A: In patients with transient ischemic attack (TIA), referral to a TIA clinic that can provide urgent investigation and initiation of preventive measures may be as effective for preventing stroke compared to impatient care.

18 Feb, 2022 | 08:29h | UTC

Risk of Subsequent Stroke Among Patients Receiving Outpatient vs Inpatient Care for Transient Ischemic Attack: A Systematic Review and Meta-analysis – JAMA Network Open

 


M-A: Association of physician continuous professional development and referrals.

18 Feb, 2022 | 08:27h | UTC

Association of Physician Continuous Professional Development and Referrals: A Systematic Review and Meta-Analysis – Academic Medicine

 


Cohort Study: Osteoporosis and its association with cardiovascular disease, respiratory disease, and cancer.

18 Feb, 2022 | 08:24h | UTC

Osteoporosis and Its Association With Cardiovascular Disease, Respiratory Disease, and Cancer: Findings From the UK Biobank Prospective Cohort Study – Mayo Clinic Proceedings (link to abstract – $ for full-text)

 


Systematic Review: Even moderate alcohol consumption can accelerate the progression of liver disease in NAFLD.

18 Feb, 2022 | 08:25h | UTC

Does moderate alcohol consumption accelerate the progression of liver disease in NAFLD? A systematic review and narrative synthesis – BMJ Open

 


Systematic Review: Vision impairment and cognitive decline among older adults.

18 Feb, 2022 | 08:19h | UTC

Vision impairment and cognitive decline among older adults: a systematic review – BMJ Open

 


Dengue infection: Global importance, immunopathology and management.

18 Feb, 2022 | 08:14h | UTC

Dengue infection: Global importance, immunopathology and management – Clinical Medicine Journal

 


Review: Cardiac considerations in liver transplantation.

18 Feb, 2022 | 08:26h | UTC

Cardiac considerations in liver transplantation – Cleveland Clinic Journal of Medicine

 


M-A: Comparative effectiveness and safety of polyethylene glycol electrolyte solution vs. lactulose for the treatment of hepatic encephalopathy.

18 Feb, 2022 | 08:18h | UTC

Comparative Effectiveness and Safety of Polyethylene Glycol Electrolyte Solution Versus Lactulose for Treatment of Hepatic Encephalopathy: A Systematic Review and Meta-analysis – Journal of Clinical Gastroenterology

 


M-A: Prevalence of anxiety and post-traumatic stress (PTS) among the parents of babies admitted to neonatal units.

18 Feb, 2022 | 08:22h | UTC

Prevalence of anxiety and post-traumatic stress (PTS) among the parents of babies admitted to neonatal units: A systematic review and meta-analysis – EClinicalMedicine

 


Review: Rickettsial illnesses, a leading cause of acute febrile illness.

18 Feb, 2022 | 08:16h | UTC

Rickettsial illnesses, a leading cause of acute febrile illness – Clinical Medicine Journal

 


Leptospirosis: clinical aspects.

18 Feb, 2022 | 08:13h | UTC

Leptospirosis: clinical aspects – Clinical Medicine Journal

 


Review: Emerging tropical neurological infections.

18 Feb, 2022 | 08:12h | UTC

Emerging tropical neurological infections – Clinical Medicine Journal

 


Cohort study: Protection against SARS-CoV-2 after Covid-19 vaccination lasts longer in patients with previous infection.

17 Feb, 2022 | 10:11h | UTC

Protection against SARS-CoV-2 after Covid-19 Vaccination and Previous Infection – New England Journal of Medicine

 


RCT: Oral Nirmatrelvir for high-risk adults with Covid-19 reduces the risk of hospitalization by 89%.

17 Feb, 2022 | 10:14h | UTC

Oral Nirmatrelvir for High-Risk, Nonhospitalized Adults with Covid-19 – New England Journal of Medicine

Audio Interview: A New Antiviral against Covid-19 – new England Journal of Medicine

Related:

[Press release – not published yet] Pfizer’s Covid pill remains 89% effective for reducing the risk of hospitalization or death in final analysis.

[Press release – not published yet] RCT: Pfizer’s novel Covid-19 oral antiviral treatment candidate reduced risk of hospitalization or death by 89% in interim analysis of phase 2/3 EPIC-HR study.

Statement on potential drug-drug interactions between Ritonavir-boosted Nirmatrelvir (Paxlovid) and concomitant medications; antiarrhythmics, oral anticoagulants, immunosuppressants, anticonvulsants, antineoplastics, and neuropsychiatric drugs are among the drugs of concern.

 

Commentary on Twitter

 


Retrospective cohort study: Pfizer vaccine reduces the risk of reinfection after recovery from Covid-19.

17 Feb, 2022 | 10:13h | UTC

Effectiveness of the BNT162b2 Vaccine after Recovery from Covid-19 – New England Journal of Medicine

 

Commentary on Twitter

 


Meta-analysis finds the overall prevalence of statin intolerance is around 9% and identifies the most common risk factors.

17 Feb, 2022 | 10:07h | UTC

Prevalence of statin intolerance: a meta-analysis – European Heart Journal

Commentaries:

Study shows the true prevalence of statin intolerance worldwide is between 6 to 10% – News Medical / European Society of Cardiology

Expert reaction to study looking at statin intolerance – Science Media Centre

Related:

Side effect patterns in a crossover trial of statin, placebo, and no treatment – This N-of-1 trial, now published in full, suggests the nocebo effect causes most of statins muscle adverse effects.

#AHA20 – In patients who had discontinued statins because of side effects, a N-of-1 trial of a statin, placebo, or no treatment found that side effects often attributed to statins were the same for those taking a placebo

 

Commentary on Twitter

 


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