Archives
Canadian recommendations on prostate cancer screening and early diagnosis.
6 Apr, 2022 | 09:47h | UTCSee also: Summary of changes
Review: Antiseizure medications for adults with epilepsy.
6 Apr, 2022 | 10:25h | UTCAntiseizure Medications for Adults With Epilepsy: A Review – JAMA (free for a limited period)
Audio Clinical Review: Epilepsy Diagnosis and Treatment in Adults – JAMA
Cohort Study: Recipient and donor outcomes after living-donor liver transplant for unresectable colorectal liver metastases.
6 Apr, 2022 | 10:23h | UTCCommentaries:
Living-Donor Liver Transplant Promising for CRC With Liver Mets – HealthDay
Commentary on Twitter
Study suggests living-donor liver transplant is a promising option for meticulously selected patients with unresectable colorectal cancer liver metastases. https://t.co/p6Jbzb73DL
— JAMA Surgery (@JAMASurgery) March 30, 2022
Review: Metabolic flexibility and its impact on health outcomes.
6 Apr, 2022 | 10:08h | UTCMetabolic Flexibility and Its Impact on Health Outcomes – Mayo Clinic Proceedings
Craniocervical artery dissections: a concise review for clinicians.
6 Apr, 2022 | 10:06h | UTCCraniocervical Artery Dissections: A Concise Review for Clinicians – Mayo Clinic Proceedings
RCT: Erythropoietin not beneficial for patients with acute kidney injury.
6 Apr, 2022 | 10:02h | UTCErythropoietin in Acute Kidney Injury (EAKI): a pragmatic randomized clinical trial – BMC Nephrology
Review: Translational advances in pancreatic ductal adenocarcinoma therapy.
6 Apr, 2022 | 10:05h | UTCTranslational advances in pancreatic ductal adenocarcinoma therapy – Nature Cancer (if the link is paywalled, try this one)
Commentary on Twitter
🔥Don't miss this beautiful review @NatureCancer on translational advances in pancreatic ductal adenocarcinoma by #AbdelNasserHosein, #StephanieKDougan, #AndrewJAguirre & @Aiims1742
Read it here🔥👇https://t.co/t6CWD0KCoxhttps://t.co/6RjCQ5NqNo
— Nature Cancer (@NatureCancer) March 29, 2022
M-A: Advanced computed tomographic localization techniques for primary hyperparathyroidism.
6 Apr, 2022 | 09:57h | UTCAdvanced Computed Tomographic Localization Techniques for Primary Hyperparathyroidism: A Systematic Review and Meta-analysis – JAMA Otolaryngology-Head & Neck Surgery (link to abstract – $ for full-text)
Opinion: Moving xenotransplantation research into human trials will require adjusting our expectations, researchers say.
6 Apr, 2022 | 09:59h | UTCRelated:
After a flurry of firsts, xenotransplantation is suddenly back in the spotlight.
In 1st, US surgeons transplant pig heart into human patient.
Review: Fulminant myocarditis in adults.
6 Apr, 2022 | 09:55h | UTCFulminant myocarditis in adults: a narrative review – Journal of Geriatric Cardiology
RCT: Higher vs. Standard Adalimumab induction and maintenance dosing regimens for treatment of ulcerative colitis.
6 Apr, 2022 | 09:56h | UTC
Review: Atrial fibrillation in older adults with cancer.
6 Apr, 2022 | 09:53h | UTCAtrial fibrillation in older adults with cancer – Journal of Geriatric Cardiology
Cohort Study: The five major autoimmune diseases are associated with increased risk of cancer.
6 Apr, 2022 | 09:52h | UTCCommentary: Increased Cancer Risk with Autoimmune Disorders – RheumNow
RCT: Rucaparib vs. standard-of-care chemotherapy in patients with relapsed ovarian cancer and a deleterious BRCA1 or BRCA2 mutation.
6 Apr, 2022 | 09:45h | UTCRucaparib versus standard-of-care chemotherapy in patients with relapsed ovarian cancer and a deleterious BRCA1 or BRCA2 mutation (ARIEL4): an international, open-label, randomised, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)
Commentary on Twitter
In ARIEL4 phase III trial, pts with BRCA1/2-mut ovarian cancer who received ≥2 chemo regimens received rucaparib or chemo. In the ITT, mPFS was 7.4 mo vs 5.7 mo (HR 0.67, 95% CI 0.52–0.86; P = 0.0017). Three treatment-related deaths occurred w rucaparib https://t.co/G7j7djp6kV
— NatureRevClinOncol (@NatRevClinOncol) March 22, 2022
Registry-based cohort study: Trends in clinical practice and outcomes after percutaneous coronary intervention of unprotected left main coronary artery.
6 Apr, 2022 | 09:50h | UTC
Review: Understanding pediatric ventilation in the operative setting.
6 Apr, 2022 | 08:42h | UTCPart I: Physical principles of monitoring in the modern anesthesia workstation – Pediatric Anesthesia
Part II: Setting perioperative ventilation – Pediatric Anesthesia
Review: Developmental respiratory physiology.
6 Apr, 2022 | 08:41h | UTCDevelopmental respiratory physiology – Pediatric Anesthesia
Billions of people still breathe unhealthy air: new WHO data.
5 Apr, 2022 | 09:59h | UTCNews Release: Billions of people still breathe unhealthy air: new WHO data – World Health Organization
Report: WHO Air quality Database 2022
Commentaries:
WHO says 99% of world’s population breathes poor-quality air – Associated Press
Related: New WHO Global Air Quality Guidelines aim to save millions of lives from air pollution.
Commentary on Twitter (thread – click for more)
Shocking!
99% – or almost the entire world's population breathes air with unhealthy levels of fine particulate matter & nitrogen dioxide, and threatens their health.
More: https://t.co/Llaj2wHk0V #HealthierTomorrow pic.twitter.com/QlHUP4iyS4— World Health Organization (WHO) (@WHO) April 4, 2022
Update on ventilatory management of extremely preterm infants—A Neonatal Intensive Care Unit perspective.
6 Apr, 2022 | 08:40h | UTC
Systematic Review: Videolaryngoscopy vs. direct laryngoscopy for adults undergoing tracheal intubation.
5 Apr, 2022 | 09:52h | UTC
Commentary from the author on Twitter (thread – click for more)
https://twitter.com/VirtueOfNothing/status/1511007812100390916
Review: Novel ventilation techniques in children.
6 Apr, 2022 | 08:38h | UTCNovel ventilation techniques in children – Pediatric Anesthesia
#ACC22 – RCT: In patients undergoing non-cardiac surgery, a strategy of aggressive intraoperative warming (target core temperature of 37°C) did not reduce major complications compared to routine thermal management (target of 35·5°C).
5 Apr, 2022 | 09:57h | UTCAggressive intraoperative warming versus routine thermal management during non-cardiac surgery (PROTECT): a multicentre, parallel group, superiority trial – The Lancet (free registration required)
Consensus Statement: Definition, diagnosis, and management of COVID-19-associated pulmonary mucormycosis.
5 Apr, 2022 | 09:54h | UTC
Perspective: The evidence on 4th doses of covid vaccines & the thorny question of age thresholds.
5 Apr, 2022 | 09:46h | UTCRelated:
U.S. approves second Covid-19 booster for people 50 and older and immunocompromised individuals.
[Preprint] Fourth dose of COVID vaccine offers only slight boost against Omicron infection.
Covid-19: Fourth vaccine doses—who needs them and why?
[Not published yet] Study in Israel finds fourth COVID booster has limited efficacy.
Commentary on Twitter
https://twitter.com/hildabast/status/1509724907965665280
Seminar: Acute coronary syndromes.
5 Apr, 2022 | 09:48h | UTCAcute coronary syndromes – The Lancet (free for a limited period)
Commentary on Twitter
https://twitter.com/TheLancet/status/1510213032143691776