Archives
Management of sleep disorders among children and adolescents with neurodevelopmental disorders: A practical guide for clinicians.
9 Jun, 2022 | 11:21h | UTC
Consensus Statement: Assessment of foot alignment and function for ambulatory children with cerebral palsy.
9 Jun, 2022 | 10:59h | UTC
Role of diet in stroke incidence: an umbrella review of meta-analyses of prospective observational studies.
9 Jun, 2022 | 10:57h | UTC
M-A: Effects of diet on the outcomes of rheumatic and musculoskeletal diseases.
9 Jun, 2022 | 10:48h | UTCNews Release: Diet unlikely to ease progression of osteoarthritis, rheumatoid arthritis – BMJ
Migraine history tied to higher risk for adverse pregnancy outcomes.
9 Jun, 2022 | 10:49h | UTCMigraine History Tied to Higher Risk for Adverse Pregnancy Outcomes – HealthDay
RCT: Short-term effectiveness of high-load compared with low-load strengthening exercise on self-reported function in patients with hypermobile shoulders.
9 Jun, 2022 | 10:44h | UTC
Commentary on Twitter
📣 LATEST #OriginalResearch
⚠️ Hypermobility spectrum disorder and shoulder symptoms
Are high-load strengthening exercises more effective at improving shoulder function than low-load⁉️
NEW #OpenAccess randomised controlled trial 📄
➡️ https://t.co/qQd8dDCdyW pic.twitter.com/jLyI3WxYRq
— British Journal of Sports Medicine (BJSM) (@BJSM_BMJ) June 4, 2022
Study shows that excessively high BMI is also associated with type 1 diabetes—not just the type 2.
9 Jun, 2022 | 10:40h | UTCNews Release: Study shows that excessively high BMI is also associated with type 1 diabetes—not just the type 2 – Diabetologia
Original Article: Obesity in late adolescence and incident type 1 diabetes in young adulthood – Diabetologia
Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study.
9 Jun, 2022 | 10:42h | UTC
Commentary on Twitter (thread – click for more)
Global impact of hospital facilities on patient outcomes after cancer surgery from @globalsurg 3, published in @LancetGH
For every 100 #cancer operations, one to three early surgical deaths could be saved with improvements to hospital resources worldwidehttps://t.co/Qiv5dSZPzb pic.twitter.com/EbSInePjI4
— Steve Knight (@sr_knight1) May 30, 2022
Under a Creative Commons Attribution (CC BY 4.0) license
Sensitivity analysis in clinical trials: three criteria for a valid sensitivity analysis.
9 Jun, 2022 | 10:36h | UTCSensitivity analysis in clinical trials: three criteria for a valid sensitivity analysis – Eye
See Special Series: Research Methodology for the Ophthalmologist – Eye
Systematic Review: Evidence-based perioperative diagnosis and management of pulmonary embolism.
9 Jun, 2022 | 10:34h | UTC
Cohort Study: Long-term quality of life in patients with breast cancer after breast conservation vs mastectomy and reconstruction.
9 Jun, 2022 | 10:30h | UTCLong-term Quality of Life in Patients With Breast Cancer After Breast Conservation vs Mastectomy and Reconstruction – JAMA Surgery (link to abstract – $ for full-text)
Commentaries:
Long-Term QOL Examined for Surgical Choices in Breast Cancer – HealthDay
Commentary on Twitter
Survey of #breastcancer survivors after treatment found:
1. Breast satisfaction and physical well-being similar with lumpectomy+rads or mastectomy+reconstruction (no rads)
2. Psychosocial well-being and sexual well-being better with lumpectomy+rads https://t.co/tPh9Pt4gYx— JAMA Surgery (@JAMASurgery) April 14, 2022
Guidance for the interpretation of continual cuffless blood pressure data for the diagnosis and management of hypertension.
9 Jun, 2022 | 10:28h | UTC
Predictors of recurrent stroke after embolic stroke of undetermined source.
9 Jun, 2022 | 10:32h | UTC
RCT: Furmonertinib vs. gefitinib as first-line therapy for patients with locally advanced or metastatic EGFR mutation-positive non-small-cell lung cancer.
9 Jun, 2022 | 10:25h | UTCFurmonertinib (AST2818) versus gefitinib as first-line therapy for Chinese patients with locally advanced or metastatic EGFR mutation-positive non-small-cell lung cancer (FURLONG): a multicentre, double-blind, randomised phase 3 study – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Systematic Review: N-Acetylcysteine for the management of non-acetaminophen drug-induced liver injury in adults.
9 Jun, 2022 | 10:27h | UTC
RCT: Abiraterone and Olaparib for metastatic castration-resistant prostate cancer.
9 Jun, 2022 | 10:21h | UTCAbiraterone and Olaparib for Metastatic Castration-Resistant Prostate Cancer – NEJM Evidence
Commentary on Twitter
Combination treatment with abiraterone and olaparib increased progression-free survival regardless of homologous recombination repair gene mutation status in patients with metastatic castration-resistant #ProstateCancer treated in the first-line setting. https://t.co/CAUDF2ZErG pic.twitter.com/YARZa8AUXJ
— NEJM Evidence (@NEJMEvidence) June 3, 2022
RCT: Tremelimumab plus Durvalumab in unresectable hepatocellular carcinoma.
9 Jun, 2022 | 10:24h | UTCTremelimumab plus Durvalumab in Unresectable Hepatocellular Carcinoma – NEJM Evidence
Commentary on Twitter
Durvalumab plus a single dose of tremelimumab increased overall survival by just over 2.5 months in patients with unresectable hepatocellular carcinoma who had not received previous systemic therapy. Read more about the HIMALAYA trial by @GABOUALFA et al.: https://t.co/8d2qp54OLt pic.twitter.com/AA1RlSEP2a
— NEJM Evidence (@NEJMEvidence) June 6, 2022
Phase 2 RCT: Upfront FOLFOXIRI plus bevacizumab with or without atezolizumab in the treatment of patients with metastatic colorectal cancer.
9 Jun, 2022 | 10:19h | UTCUpfront FOLFOXIRI plus bevacizumab with or without atezolizumab in the treatment of patients with metastatic colorectal cancer (AtezoTRIBE): a multicentre, open-label, randomised, controlled, phase 2 trial – The Lancet Oncology (link to abstract – $ for full-text)
Commentary on Twitter
In phase II AtezoTRIBE study of the addition of atezolizumab to first-line FOLFOXIRI + bevacizumab improved PFS in pts with pMMR/MSS mCRC (median 13.1 vs 11.5 months; adjusted HR 0.70, 80% CI 0.57–0.87; P = 0.018): https://t.co/0dkRxjvjsx #ImmunoOnc #CRCSM
— NatureRevClinOncol (@NatRevClinOncol) May 31, 2022
Fixed-duration ibrutinib plus venetoclax for first-line treatment of CLL: primary analysis of the CAPTIVATE FD cohort.
9 Jun, 2022 | 10:17h | UTC
Statement on initial antimicrobial treatment of sepsis.
8 Jun, 2022 | 11:17h | UTCStatement on initial antimicrobial treatment of sepsis – Faculty of Intensive Care Medicine
Commentary on Twitter
🚨Statement on initial antimicrobial treatment of sepsis🚨
Full statement and documents available➡️ https://t.co/jWexX1VDDd @AoMRC pic.twitter.com/kQdJrZ2hOA
— FICMNews (@FICMNews) June 4, 2022
RCT: Effect of electronic symptom monitoring on patient-reported outcomes among patients with metastatic cancer.
8 Jun, 2022 | 11:14h | UTCEffect of Electronic Symptom Monitoring on Patient-Reported Outcomes Among Patients With Metastatic Cancer: A Randomized Clinical Trial – JAMA (free for a limited period)
Related:
Digital remote monitoring plus usual care versus usual care in patients treated with oral anticancer agents: the randomized phase 3 CAPRI trial – Nature Medicine (if the link is paywalled, try this one)
Key components of successful digital remote monitoring in oncology – Nature Medicine
International consensus classification of mature lymphoid neoplasms.
9 Jun, 2022 | 10:15h | UTC
Cross sectional study: accuracy difference of noninvasive blood pressure measurements by sex and height.
8 Jun, 2022 | 11:11h | UTCAccuracy Difference of Noninvasive Blood Pressure Measurements by Sex and Height – JAMA Network Open
Invited Commentary: Sex Differences in Blood Pressure—A Measured Relook at Measures
Commentary on Twitter
This cross-sectional study found non-invasive blood pressure accuracy is influenced by sex, with the brachial cuff greatly underestimating the true aortic systolic blood pressure in females, but not in males, mostly mediated by height differences. https://t.co/7Ubk8ve2ic
— JAMA Network Open (@JAMANetworkOpen) June 7, 2022
‘Helicopter research’ comes under fire at Cape Town conference – statement presses for equity when scientists from wealthy nations do research in poorer ones.
8 Jun, 2022 | 11:11h | UTC‘Helicopter research’ comes under fire at Cape Town conference – Science
Reducing SARS-CoV-2 in shared indoor air.
8 Jun, 2022 | 11:07h | UTCReducing SARS-CoV-2 in Shared Indoor Air – JAMA