Archives
Brief Review | Sudden onset hepatitis in children.
4 Jul, 2022 | 12:41h | UTCSudden onset hepatitis in children – Nature Reviews Gastroenterology & Hepatology (if the link is paywalled, try this one)
Related: WHO Updated Report: Severe acute hepatitis of unknown etiology in children. (several articles on the subject)
Commentary on Twitter
NEW! In this COMMENT by @ZaniaStamataki & @kellyda60 summarise what we know so far about sudden onset #hepatitis of unexplained origin in childrenhttps://t.co/AYTR8wrG3C
Read-only link https://t.co/dgyzRhpODT#paediatrics pic.twitter.com/1WLQfaRrdx
— Nature Reviews Gastroenterology & Hepatology (@NatRevGastroHep) July 1, 2022
Consensus Guidance | Updated treatment recommendations for psoriatic arthritis.
4 Jul, 2022 | 12:31h | UTCGroup for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA): updated treatment recommendations for psoriatic arthritis 2021 – Nature Reviews Rheumatology (if the link is paywalled, try this one in PMC Central)
See also (just published): Update on the Management of Pediatric Psoriasis: An Italian Consensus – Dermatology and Therapy
Related:
Executive summary: The 2022 British Society for Rheumatology guideline for the treatment of psoriatic arthritis with biologic and targeted synthetic DMARDs – Rheumatology
Spondyloarthritis in over 16s: diagnosis and management – NICE Updated Guideline
Monkeypox soars in Europe, with more than 4,000 cases.
4 Jul, 2022 | 12:43h | UTCMonkeypox soars in Europe, with more than 4,000 cases – CIDRAP
Original Report: European Centre for Disease Prevention and Control/WHO Regional Office for Europe. Monkeypox, Joint Epidemiological overview, 30 June, 2022
WHO Statement: No room for complacency – World Health Organization
Related:
Multi-country monkeypox outbreak: situation update – World Health Organization
Monkeypox Genital Lesions – New England Journal of Medicine
Monkeypox vaccination begins — can the global outbreaks be contained? – Nature
Incubation period for monkeypox: Estimates from the Netherlands.
‘Discriminatory and stigmatizing’: Scientists push to rename monkeypox viruses – STAT
Rename monkeypox strains to remove geographic stigma, researchers say – Science
2022 Monkeypox and Orthopoxvirus Outbreak Global Map – Centers for Disease Control and Prevention
As monkeypox threat grows, scientists debate best vaccine strategy – Science
Monkeypox is a new global threat. African scientists know what the world is up against – Science
Experts highlight sexual aspect of monkeypox spread – CIDRAP
What to Know About Monkeypox – JAMA
Multi-country monkeypox outbreak in non-endemic countries: Update – World Health Organization
Monkeypox outbreaks: 4 key questions researchers have – Nature
Study reports first use of antivirals in monkeypox patients – Lancet
Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization
Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization
A Novel International Monkeypox Outbreak – Annals of Internal Medicine
EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT
Monkeypox cases increase across Europe, North America – CIDRAP
Multi-country monkeypox outbreak in non-endemic countries – World Health Organization
Monkeypox goes global: why scientists are on alert – Nature
Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT
Monkeypox: Time to worry or one to ignore? – BBC
UK, Spain, Portugal report more monkeypox cases – CIDRAP
U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT
Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization
Monkeypox cases confirmed in England – latest updates – UK Health Security Agency
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch
European outbreak of monkeypox: what you need to know – The Conversation
Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR
Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News
Guideline | Malignancy risk stratification for solitary pulmonary nodule.
4 Jul, 2022 | 12:33h | UTCPharmacological treatment of early-onset schizophrenia: a critical review, evidence-based clinical guidance, and unmet needs.
4 Jul, 2022 | 12:29h | UTCGlobal burden of musculoskeletal disorders and attributable factors in 204 countries and territories: a secondary analysis of the Global Burden of Disease 2019 study.
4 Jul, 2022 | 12:24h | UTCRelated: The Global Burden of Musculoskeletal Pain—Where to From Here? – American Journal of Public Health
A guideline and checklist for initiating and managing Clozapine treatment in patients with treatment-resistant schizophrenia.
4 Jul, 2022 | 12:27h | UTCUsing the intranasal route to administer drugs to treat neurological and psychiatric illnesses: rationale, successes, and future needs.
4 Jul, 2022 | 12:26h | UTCUsing the Intranasal Route to Administer Drugs to Treat Neurological and Psychiatric Illnesses: Rationale, Successes, and Future Needs – CNS Drugs (if the link is paywalled, try this one)
RCT | Effect of levofloxacin on the efficacy and adverse events in intravesical Bacillus Calmette-Guerin treatment for bladder cancer.
4 Jul, 2022 | 12:19h | UTCRCT | CT vs. [18F]FDG-PET-CT for persistent or recurrent neutropenic fever in high-risk patients.
4 Jul, 2022 | 12:21h | UTC[18F]FDG-PET-CT compared with CT for persistent or recurrent neutropenic fever in high-risk patients (PIPPIN): a multicentre, open-label, phase 3, randomised, controlled trial – The Lancet Haematology (link to abstract – $ for full-text)
Commentary on Twitter
NEW research: [18F]FDG-PET-CT resulted in more frequent antimicrobial rationalisation than CT in patients w/ haem diseases & persistent/recurrent high-risk neutropenic fever after chemotherapy. Results of the ph3 RCT PIPPIN #radonc #hemonc https://t.co/isOPFZVVpY pic.twitter.com/PVd8yFy7Ck
— The Lancet Haematology (@TheLancetHaem) June 29, 2022
M-A | Antibiotics for preventing recurrent urinary tract infection.
4 Jul, 2022 | 12:17h | UTCBrief Review | Ventilator-associated pneumonia.
4 Jul, 2022 | 12:15h | UTCVentilator-associated pneumonia – Intensive Care Medicine (if the link is paywalled, try this one in PMC)
Commentary on Twitter
VAP, main challenges & lessons learned
➡️ epidemiology: surveillance & data from LMICs
➡️ pathophysiology
➡️ prevention bundle
➡️ gold standard for diagnosis & microbiology
➡️ treatment: appropriate/timely ABTs
➡️ MDR pathogens
➡️ #COVID19: VAP's back
📎 https://t.co/oYblI6OGLK pic.twitter.com/qXWcABsU0H— Intensive Care Medicine (@yourICM) July 1, 2022
Review | Lowering and raising serum urate levels: off-label effects of commonly used medications.
4 Jul, 2022 | 12:10h | UTCHow doctors manage conflicts with families of critically ill patients during conversations about end-of-life decisions in neonatal, pediatric, and adult intensive care.
4 Jul, 2022 | 12:13h | UTCM-A of randomized trials | Ondansetron vs. metoclopramide for managing hyperemesis gravidarum.
4 Jul, 2022 | 12:11h | UTCPhase 1 single-arm study | Oncolytic DNX-2401 virus for pediatric diffuse intrinsic pontine glioma.
4 Jul, 2022 | 12:08h | UTCOncolytic DNX-2401 Virus for Pediatric Diffuse Intrinsic Pontine Glioma – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Oncolytic Virus Infusion Promising as Brain-Stem Glioma Treatment — Phase I trial shows encouraging OS in children with diffuse intrinsic pontine glioma – MedPage Today (free registration required)
Trends in advanced heart failure therapy: update on cardiac transplantation.
4 Jul, 2022 | 12:07h | UTCM-A of randomized trials | Tourniquet use in total knee arthroplasty and the risk of infection.
4 Jul, 2022 | 11:55h | UTCFDA warns about possible increased risk of death and serious side effects with duvelisib.
4 Jul, 2022 | 11:51h | UTCCohort Study | Novel risk prediction model to determine adverse heart failure outcomes in arrhythmogenic right ventricular cardiomyopathy.
4 Jul, 2022 | 11:53h | UTCEditorial: Predicting Heart Failure in Arrhythmogenic Right Ventricular Cardiomyopathy
2022 Guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer, including patients with COVID-19.
1 Jul, 2022 | 11:50h | UTCRelated:
Editorial | Circulating tumor cell burden as a component of staging in multiple myeloma: ready for prime time?
4 Jul, 2022 | 11:48h | UTCOriginal Studies:
Two new studies show no benefit of Enoxaparin for primary thromboprophylaxis in symptomatic outpatients with COVID-19.
1 Jul, 2022 | 11:49h | UTCCommentaries:
Antithrombotic Prophylaxis No Help in Outpatients With COVID — Two trials show no differences between patients who received enoxaparin vs standard of care – MedPage Today (free registration required)
Commentary on Twitter (thread – click for more)
Early in the pandemic we wondered whether antithrombotic therapy in outpatients with #COVID19 would prevent #thrombosis ❓
Several trials were started globally and the ACTIV-4B trial was previously reported⬇️ https://t.co/Q15WcZwDIA
Now, we publish the OVID and ETHIC trials🧵
— The Lancet Haematology (@TheLancetHaem) June 30, 2022
Systematic Review: Mobility training for increasing mobility and functioning in older people with frailty.
1 Jul, 2022 | 11:41h | UTC
RCT: A single immediate dose of intravenous tenecteplase is noninferior to alteplase for the treatment of patients with acute ischemic stroke.
1 Jul, 2022 | 11:44h | UTCIntravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised, controlled, non-inferiority trial – The Lancet (link to abstract – $ for full-text)
News Release: UCalgary researchers with the Calgary Stroke Program make another breakthrough in the treatment of stroke