Archives
Phase 1-2 study | Lentiviral gene therapy for artemis-deficient SCID
12 Jan, 2023 | 12:59h | UTCLentiviral Gene Therapy for Artemis-Deficient SCID – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Infant gene therapy is a breakthrough for Artemis-SCID patients – University of California – San Francisco
Commentary on Twitter
Severe combined immunodeficiency caused by mutations in the gene encoding a DNA-repair enzyme called Artemis is difficult to treat. This study involving 10 patients supports a gene-therapy approach. https://t.co/SCpZjOQtMW pic.twitter.com/VRYOje6UPV
— NEJM (@NEJM) December 22, 2022
M-A | Blood endotoxin levels as biomarker of non-alcoholic fatty liver disease
12 Jan, 2023 | 12:57h | UTC
Phase 2 RCT | Upfront autologous HSCT vs. carfilzomib–cyclophosphamide–dexamethasone consolidation with carfilzomib maintenance in multiple myeloma
12 Jan, 2023 | 12:56h | UTCInvited Commentary: Upfront autologous transplantation still improving outcomes in patients with multiple myeloma – The Lancet Haematology
M-A | The prevalence of obesity among children with type 2 DM
12 Jan, 2023 | 12:53h | UTCCommentary: Not All Pediatric Cases of Type 2 Diabetes Have Obesity – HealthDay
Commentary on Twitter
Meta-analysis finds that 75% of children with type 2 diabetes have obesity; not all pediatric T2DM patients have obesity. Further studies are needed to investigate the mechanisms beyond obesity driving this condition in children. https://t.co/RsDVSDq7rq
— JAMA Network Open (@JAMANetworkOpen) December 16, 2022
Phase 2 RCT | No benefit from the Bruton’s tyrosine kinase inhibitor Evobrutinib in systemic lupus erythematosus
12 Jan, 2023 | 12:54h | UTC
Review | Antithrombotic therapy after bioprosthetic aortic valve replacement
12 Jan, 2023 | 12:51h | UTC
Acute kidney injury-associated delirium: a review of clinical and pathophysiological mechanisms
12 Jan, 2023 | 12:50h | UTC
A multidisciplinary approach for the emergency care of patients with left ventricular assist devices
12 Jan, 2023 | 12:49h | UTC
Review | Early diagnosis and prevention of infections in cirrhosis
12 Jan, 2023 | 12:47h | UTCEarly Diagnosis and Prevention of Infections in Cirrhosis – Seminars in Liver Disease
Review | The outcome of neurorehabilitation efficacy and management of traumatic brain injury
12 Jan, 2023 | 12:46h | UTC
Statement | Pre-procedure and pre-admission COVID-19 testing no longer recommended for asymptomatic patients
11 Jan, 2023 | 14:36h | UTCRecommendation Statement: Asymptomatic screening for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) as an infection prevention measure in healthcare facilities: Challenges and considerations – Infection Control & Hospital Epidemiology
Commentary: Infectious disease board recommends hospitals stop screening asymptomatic patients for Covid-19 – STAT
Nonconvulsive status epilepticus following cardiac arrest: overlooked, untreated and misjudged
12 Jan, 2023 | 12:43h | UTC
NICE Guideline | Thyroid cancer: assessment and management
11 Jan, 2023 | 14:34h | UTCThyroid cancer: assessment and management – National Institute for Health and Care Excellence
RCT | In patients with AF undergoing ablation, the addition of posterior wall isolation to pulmonary vein isolation (PVI) was not better than PVI alone
11 Jan, 2023 | 14:33h | UTCEffect of Catheter Ablation Using Pulmonary Vein Isolation With vs Without Posterior Left Atrial Wall Isolation on Atrial Arrhythmia Recurrence in Patients With Persistent Atrial Fibrillation: The CAPLA Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Catheter Ablation for Persistent Atrial Fibrillation – JAMA (free for a limited period)
See also: Visual abstract
Review | Autism spectrum disorder
11 Jan, 2023 | 14:31h | UTCAutism Spectrum Disorder: A Review – JAMA (free for a limited period)
Circulating spike protein detected in post–COVID-19 mRNA vaccine myocarditis
11 Jan, 2023 | 14:30h | UTCCirculating Spike Protein Detected in Post–COVID-19 mRNA Vaccine Myocarditis – Circulation
Commentary: Free spike proteins in the blood appear to play a role in myocarditis post-COVID mRNA vaccine – News Medical
Review | Durability of vaccine-induced and natural immunity against COVID-19
11 Jan, 2023 | 14:29h | UTC
Perspective | The limits of shared decision making
11 Jan, 2023 | 14:28h | UTCThe limits of shared decision making – BMJ Evidence-Based Medicine
RCT | Dupilumab in adults and adolescents with eosinophilic esophagitis
11 Jan, 2023 | 14:27h | UTCDupilumab in Adults and Adolescents with Eosinophilic Esophagitis – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Weekly Dupilumab Beneficial in Eosinophilic Esophagitis – HealthDay
Monkeypox (hMPXV infection): a practical review
11 Jan, 2023 | 14:25h | UTCMonkeypox (hMPXV infection): A practical review – American Journal of Medicine
Consensus Document | Management of infants and neonates with tetralogy of Fallot
11 Jan, 2023 | 14:21h | UTC
Commentary on Twitter
AATS announces the publication of “The Management of Infants and Neonates with Tetralogy of Fallot" in #JTCVS! Read the AATS 2022 Expert Consensus Document here: https://t.co/gyWgSkZ6BB @EHStephensCHD @abgoldstoneMD @LCKaneMD @RickOhyeMD @Dr_dUdekem @tssmn #CHD #tetralogyofFallot pic.twitter.com/5nam4bpfbN
— AATS Journals (@AATSJournals) October 27, 2022
SR | Efficacy of presurgical interventions to promote smoking cessation
11 Jan, 2023 | 14:24h | UTC
Consensus Document | The use of mechanical circulatory support in lung transplantation
11 Jan, 2023 | 14:18h | UTC
Commentary on Twitter
https://twitter.com/AATSJournals/status/1585645197639450624
Guideline | Hearing loss in children
11 Jan, 2023 | 14:16h | UTC
Cancer care for people with dementia: literature overview and recommendations for practice and research
11 Jan, 2023 | 14:14h | UTC