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Prevention of everolimus-related stomatitis

30 Mar, 2017 | 17:24h | UTC

Prevention of everolimus-related stomatitis in women with hormone receptor-positive, HER2-negative metastatic breast cancer using dexamethasone mouthwash (SWISH): a single-arm, phase 2 trial – The Lancet Oncology (link to abstract – $ required for full-text)

See also: SWISH Four Times a Day to Keep Oral Mucositis Away – Medscape (free registration required)

This simple and inexpensive treatment resulted in a more than ten-times reduction in the incidence of grade 2 or higher stomatitis.

 


I have cancer. This comic shows how much pressure I feel to be a hero

29 Mar, 2017 | 17:10h | UTC

I have cancer. This comic shows how much pressure I feel to be a hero – VOX (free)

Source: STAT Newsletter

Interesting read…

 


WHO Launches Global Effort to Halve Medication-Related Errors in 5 Years

30 Mar, 2017 | 17:30h | UTC

Press release: WHO Launches Global Effort to Halve Medication-Related Errors in 5 Years – World Health Organization (free)

See also: WHO’s work on patient safety (free) AND WHO Global Patient Safety Challenge on Medication Safety (free) AND WHO Educational materials for medication safety (free)

 


Putting Patients First by Reducing Administrative Tasks in Health Care

29 Mar, 2017 | 17:13h | UTC

Putting Patients First by Reducing Administrative Tasks in Health Care: A Position Paper of the American College of Physicians (free)

See also: ACP: Stop Saddling Docs With Administrative Tasks – MedPage Today (free registration required)

“It’s time for all those involved in the healthcare industry to reevaluate and reduce the administrative task burden placed on clinicians” (from MedPage commentary above).

 


Ten Steps to Producing a Well-Written Evidence-Based Health Care Dissertation

30 Mar, 2017 | 17:20h | UTC

Ten Steps to Producing a Well-Written Evidence-Based Health Care Dissertation – Centre for Evidence-Based Medicine, University of Oxford (free)

 


HERDOO2 rule to guide treatment duration for women with unprovoked venous thrombosis

29 Mar, 2017 | 17:07h | UTC

Validating the HERDOO2 rule to guide treatment duration for women with unprovoked venous thrombosis: multinational prospective cohort management study – The BMJ (free)

Source: Richard Lehman’s weekly review

HERDOO2 rule stands for Hyperpigmentation, Edema, or Redness in either leg; D-dimer level ≥250 μg/L; Obesity with body mass index ≥30; or Older age, ≥65 years. The authors concluded that women with a first unprovoked VTE event and none or one of the HERDOO2 criteria have a low risk (3.0% per patient year) of recurrent VTE and can safely discontinue anticoagulants after completing short term treatment.

 


Prevention and Treatment of Substance Use Disorders

29 Mar, 2017 | 17:12h | UTC

Effective Prevention and Treatment of Substance Use Disorders – An American College of Physicians Position Paper (free)

See also: Treat Substance Abuse as Chronic Condition, ACP Says – Medscape (free registration required) AND Physicians call for drug abuse to be treated as ‘chronic disease’ – ABCNews (free)

 


Antibiotic Therapy versus Appendectomy for Acute Uncomplicated Appendicitis

29 Mar, 2017 | 17:05h | UTC

Comparison of Antibiotic Therapy and Appendectomy for Acute Uncomplicated Appendicitis in Children: A Meta-analysis – JAMA Pediatrics(free)

Editorial: Medical Treatment of Pediatric Appendicitis: Are We There Yet? (free)

See also a recent meta-analysis and related commentaries on the same subject (free)

Nonoperative treatment was successful in 90% of cases. Subgroup analysis indicated an increased risk for initial fails and recurrent appendicitis in those with appendicolith.

 


New recommendations for the management of rheumatoid arthritis

29 Mar, 2017 | 17:09h | UTC

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs – Annals of Rheumatic Diseases (free)

See also: EULAR Releases New RA Tx Recommendations: Focus is on conventional agents, biologics, and targeted synthetic drugs – MedPage Today(free registration required)

Source: EvidenceAlerts Newsletter

 


Wed, Mar 29 – Top 10 Medical News Stories

29 Mar, 2017 | 00:01h | UTC

 

1 – Putting Patients First by Reducing Administrative Tasks in Health Care: A Position Paper of the American College of Physicians (free)

See also: ACP: Stop Saddling Docs With Administrative Tasks – MedPage Today (free registration required)

“It’s time for all those involved in the healthcare industry to reevaluate and reduce the administrative task burden placed on clinicians” (from MedPage commentary above).

 

2 – Effective Prevention and Treatment of Substance Use Disorders – An American College of Physicians Position Paper (free)

See also: Treat Substance Abuse as Chronic Condition, ACP Says – Medscape (free registration required) AND Physicians call for drug abuse to be treated as ‘chronic disease’ – ABCNews (free)

 

3 – I have cancer. This comic shows how much pressure I feel to be a hero – VOX (free)

Source: STAT Newsletter

Interesting read…

 

4 – EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs – Annals of Rheumatic Diseases (free)

See also: EULAR Releases New RA Tx Recommendations: Focus is on conventional agents, biologics, and targeted synthetic drugs – MedPage Today (free registration required)

Source: EvidenceAlerts Newsletter

 

5 – Validating the HERDOO2 rule to guide treatment duration for women with unprovoked venous thrombosis: multinational prospective cohort management study – The BMJ (free)

Source: Richard Lehman’s weekly review

HERDOO2 rule stands for Hyperpigmentation, Edema, or Redness in either leg; D-dimer level ≥250 μg/L; Obesity with body mass index ≥30; or Older age, ≥65 years. The authors concluded that women with a first unprovoked VTE event and none or one of the HERDOO2 criteria have a low risk (3.0% per patient year) of recurrent VTE and can safely discontinue anticoagulants after completing short term treatment.

 

6 – Comparison of Antibiotic Therapy and Appendectomy for Acute Uncomplicated Appendicitis in Children: A Meta-analysis – JAMA Pediatrics (free)

Editorial: Medical Treatment of Pediatric Appendicitis: Are We There Yet? (free)

See also a recent meta-analysis and related commentaries on the same subject (free)

Nonoperative treatment was successful in 90% of cases. Subgroup analysis indicated an increased risk for initial fails and recurrent appendicitis in those with appendicolith.

 

7 – Screening for Celiac Disease: US Preventive Services Task Force Recommendation Statement (free)

Editorial 1: The US Preventive Services Task Force Recommendation on Screening for Asymptomatic Celiac Disease: A Dearth of Evidence (free)

Editorial 2: Celiac Disease and Nonceliac Gluten or Wheat Sensitivity: The Risks and Benefits of Diagnosis (free)

“Some sanity about screening for asymptomatic celiac disease in the gluten-free diet “epidemic” era” (RT @EricTopol see Tweet)

 

8 – Value-Based Purchasing: Time for Reboot or Time to Move On? by Ashish K. Jha, MD – The JAMA Forum (free)

Pay-for-performance (P4P) as a policy tool does not seem to be improving health care quality or lowering costs.

 

9 – The year in cardiology 2016: peripheral circulation – European Heart Journal (free)

 

10 – Regression to the mean, or why perfection rarely lasts – The Conversation (free) (RT @PaulGlasziou)

“Regression to the mean, and its importance in healthcare decisions” (RT @Tammy_Hoffmann see Tweet)

 


Screening for Celiac Disease

29 Mar, 2017 | 17:04h | UTC

Screening for Celiac Disease: US Preventive Services Task Force Recommendation Statement (free)

Editorial 1: The US Preventive Services Task Force Recommendation on Screening for Asymptomatic Celiac Disease: A Dearth of Evidence (free)

Editorial 2: Celiac Disease and Nonceliac Gluten or Wheat Sensitivity: The Risks and Benefits of Diagnosis (free)

“Some sanity about screening for asymptomatic celiac disease in the gluten-free diet “epidemic” era” (RT @EricTopol see Tweet)

 


The year in cardiology 2016: peripheral circulation

29 Mar, 2017 | 17:00h | UTC

The year in cardiology 2016: peripheral circulation – European Heart Journal (free)

 


WHO releases new guidance on malaria elimination

28 Mar, 2017 | 16:57h | UTC

A framework for malaria elimination – World Health Organization (free) (RT @Onisillos)

News release: WHO releases new guidance on malaria elimination (free)

“Updated 2017 framework gives guidance, tools, activities and strategies to achieve malaria elimination, 10 years on” (RT @MalariaAtlas)

 


Value-Based Purchasing: Time for Reboot or Time to Move On?

29 Mar, 2017 | 17:03h | UTC

Value-Based Purchasing: Time for Reboot or Time to Move On? by Ashish K. Jha, MD – The JAMA Forum (free)

Pay-for-performance (P4P) as a policy tool does not seem to be improving health care quality or lowering costs.

 


A.I. VERSUS M.D

28 Mar, 2017 | 16:52h | UTC

A.I. VERSUS M.D – What happens when diagnosis is automated? – The New Yorker (free) (RT @EricTopol)

“In some trials, “deep learning” systems have outperformed human experts.”

 


Regression to the mean, and its importance in healthcare decisions

29 Mar, 2017 | 16:59h | UTC

Regression to the mean, or why perfection rarely lasts – The Conversation (free) (RT @PaulGlasziou)

“Regression to the mean, and its importance in healthcare decisions” (RT @Tammy_Hoffmann see Tweet)

 


Richard Lehman’s weekly review

28 Mar, 2017 | 16:50h | UTC

Richard Lehman’s weekly review of medical journals, 27 March 2017 – The BMJ Blogs (free)

 


Medical School’s Hidden Flaws and Hard Lessons

28 Mar, 2017 | 16:53h | UTC

The Comics Revealing Medical School’s Hidden Flaws and Hard Lessons – The Atlantic (free)

Source: Global Health Now Newsletter

Very interesting read…

 


Gastric Acid Suppression and Clostridium difficile Infection

28 Mar, 2017 | 16:54h | UTC

Association of Gastric Acid Suppression with Recurrent Clostridium difficile Infection: A Systematic Review and Meta-analysis (link to abstract – $ required for full-text)

“Another study that suggests gastric acid suppression may increase risk of recurrent Clostridium difficile” (RT @PreetiNMalani)

 


Teleretinal Diabetic Retinopathy Screening

28 Mar, 2017 | 16:55h | UTC

Implementation and Evaluation of a Large-Scale Teleretinal Diabetic Retinopathy Screening Program in the Los Angeles County Department of Health Services – JAMA Internal Medicine (free) (RT @PreetiNMalani)

Editorial: Seeing the Effect of Health Care Delivery Innovation in the Safety Net (free)

A large-scale telemedicine diabetic retinopathy screening program increased overall rates of screening by 16.3%, and wait times for screening were reduced by 89.2%.

 


Diagnosis of chronic thromboembolic pulmonary hypertension

28 Mar, 2017 | 16:41h | UTC

Review: Diagnosis of chronic thromboembolic pulmonary hypertension – European Respiratory Review (free)

 


Healthcare Quality and Safety Online Course

28 Mar, 2017 | 16:50h | UTC

Just Started: Leading Healthcare Quality and Safety – Free Online Course from The George Washington University and Coursera (free)

 


ESPEN guideline: Clinical nutrition in surgery

27 Mar, 2017 | 00:54h | UTC

ESPEN guideline: Clinical nutrition in surgery – Clinical Nutrition (free)

Source: Critical Care Reviews Newsletter

 


Gates Foundation announces open-access publishing venture

27 Mar, 2017 | 00:59h | UTC

Gates Foundation announces open-access publishing venture – Nature News (free)

See also: Open science: The findings of medical research are disseminated too slowly – That is about to change – The Economist (free) AND Cooming Soom: Gates Open Research – Bill and Melinda Gates foundation (free) AND Gates Foundation joins shift towards open access platforms – Times Higher Education (free) AND Gates Open Research: the journey continues – F1000 Blog (free)

Another victory for open science.

 


Enhanced recovery after surgery

28 Mar, 2017 | 16:43h | UTC

Enhanced recovery after surgery: Current research insights and future direction – World Journal of Gastrointestinal Surgery (free)

 


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