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Mitral valve prolapse and Marfan syndrome

16 Aug, 2017 | 20:12h | UTC

Review: Mitral valve prolapse and Marfan syndrome – Congenital Heart Disease (free)

 


Role of nutrition support in adult cardiac surgery

16 Aug, 2017 | 19:48h | UTC

Role of nutrition support in adult cardiac surgery: a consensus statement from an International Multidisciplinary Expert Group on Nutrition in Cardiac Surgery – Critical Care (free)

 


Sexual health concerns after cancer treatment in women

16 Aug, 2017 | 20:08h | UTC

Review: A comprehensive review of sexual health concerns after cancer treatment and the biopsychosocial treatment options available to female patients – European Journal of Cancer Care (free)

Commentary: Sexual Dysfunction in Women With Cancer: A Review of Available Interventions – Oncology Nurse Adviser (free)

 


The Future of Peer Review

16 Aug, 2017 | 18:09h | UTC

The Future of Peer Review – Scientific American (free)

“It’s very far from perfect, but major changes for the better are underway”

 


Facing Surgery Without An Anesthesiologist On Hand

16 Aug, 2017 | 18:13h | UTC

Global Health: Imagine: Facing Surgery Without An Anesthesiologist On Hand – NPR Goats and Soda (free)

 


Working up high: Hospitalist practice is different at altitude

16 Aug, 2017 | 15:44h | UTC

Working up high: Hospitalist practice is different at altitude – ACP Hospitalist (free)

Related reviews: Acute high-altitude sickness – European Respiratory Review (free) AND Chronic Mountain Sickness: Clinical Aspects, Etiology, Management, and Treatment – High Altitude Medicine & Biology (free)

 


Pig genome editing with goal of providing organs for transplant

16 Aug, 2017 | 18:04h | UTC

Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9 – Science (link to abstract – $ for full-text)

Commentaries: Birth of CRISPR’d pigs advances hopes for turning swine into organ donos – STAT (free) AND Gene editing to remove viruses brings transplant organs from pigs a step closer – The Guardian (free) AND Gene Editing Spurs Hope for Transplanting Pig Organs Into Humans – New York Times (10 articles per month are free) AND Gene editing brings pig organ transplant closer – NHS Choices (free) AND Scientists edit pig genome with goal of human organ transplants – CNN (free text and video)

 


Pioglitazone may increase bladder cancer risk

16 Aug, 2017 | 15:07h | UTC

Comparative safety of pioglitazone versus clinically meaningful treatment alternatives concerning the risk of bladder cancer in older US adults with type 2 diabetes – Diabetes, Obesity and Metabolism (link to abstract – $ for full-text)

Commentaries: Another Study Ties Pioglitazone to Bladder Cancer Risk – MedPage Today (free registration required) AND Diabetes Treatments Compared for Bladder Cancer Risk – MPR (free)

 


An order not to hospitalize

16 Aug, 2017 | 15:17h | UTC

An order not to hospitalize – ACP Hospitalist (free)

Original article: Are Hospital/ED Transfers Less Likely Among Nursing Home Residents With Do-Not-Hospitalize Orders? – Journal of Post-Acute and Long-Term Care Medicine (link to abstract – $ for full-text)

 


Epilepsy ‘Not a Rare Condition’

16 Aug, 2017 | 14:23h | UTC

Report: National and State Estimates of the Numbers of Adults and Children with Active Epilepsy — United States, 2015 – CDC MMWR (free)

Commentaries: Epilepsy Isn’t As Rare As Many Might Think – And Cases Are Increasing – Forbes (free) AND Epilepsy ‘Not a Rare Condition’ – MedPage Today (free registration required)

 


Syphilis in the ED: Presentations, Diagnosis, and Management of the Great Imitator

16 Aug, 2017 | 15:49h | UTC

Syphilis in the ED: Presentations, Diagnosis, and Management of the Great Imitator – emDocs (free)

 


Guidelines for diagnosis, treatment and follow-up of patients with leptomeningeal metastasis from solid tumours

16 Aug, 2017 | 15:03h | UTC

EANO–ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up of patients with leptomeningeal metastasis from solid tumours – Annals of Oncology (free)

 


An Automated, Pharmacist-Driven Initiative Improves Quality of Care for Staphylococcus aureus Bacteremia

16 Aug, 2017 | 15:11h | UTC

An Automated, Pharmacist-Driven Initiative Improves Quality of Care for Staphylococcus aureus Bacteremia – Clinical Infectious Diseases (link to abstract – $ for full-text)

Commentaries: Automating antimicrobial stewardship – ACP Hospitalist (free) AND Automated intervention aids treatment of Staph aureus bacteremia – CIDRAP (free)

 


New, Revised Guidance Documents Cover 35 Radiology Topics

16 Aug, 2017 | 14:28h | UTC

Updated: Practice Parameters and Technical Standards – American College of Radiology (free)

News release: New, Revised Guidance Documents Cover 35 Radiology Topics – American College of Radiology, via NewsWise (free)

The American College of Radiology developed 3 new guidance documents and revised 32 others to advance the science of radiology and improve the quality of service to patients

 


The Risk of Adverse Pregnancy Outcomes Following Nonobstetric Surgery During Pregnancy

16 Aug, 2017 | 13:31h | UTC

The Risk of Adverse Pregnancy Outcomes Following Nonobstetric Surgery During Pregnancy: Estimates From a Retrospective Cohort Study of 6.5 Million Pregnancies – Annals of Surgery (free)

Source: Journal Watch ($)

“we found that the risk associated with nonobstetric surgery was relatively low, confirming that surgical procedures during pregnancy are generally safe”

 


Study: diet soda can really mess with your metabolism

16 Aug, 2017 | 14:15h | UTC

Study: diet soda can really mess with your metabolism – VOX (free)

Original article: Integration of Sweet Taste and Metabolism Determines Carbohydrate Reward – Current Biology (link to abstract – $ for full-text)

See also a related meta-analysis showing little evidence of artificial sweeteners for weight loss in our July 18th issue (see #2)

“New research helps explain why artificial sweeteners are linked to obesity and metabolic disease”.

 


Standards for Diabetes Self-management Education and Support

16 Aug, 2017 | 13:20h | UTC

2017 National Standards for Diabetes Self-management Education and Support – The Diabetes Educator (free)

Commentaries: ADA and AADE Update Standards for Diabetes Self-Management Education and Support – AJMC (free) AND Diabetes groups update standards for self-management – ACP Diabetes (free)

 


Occupation and Risk of Developing Rheumatoid Arthritis

16 Aug, 2017 | 14:03h | UTC

Occupation and Risk of Developing Rheumatoid Arthritis: Results From a Population-Based Case-Control Study – Arthritis Care & Research (link to abstract – $ for full-text)

Commentaries: Certain occupations linked to an increased risk of rheumatoid arthritis – Willey, via EurekAlert (free) AND Occupational Exposures Increase Rheumatoid Arthritis Risk – Medscape (free registration required) AND Some jobs tied to higher risk of rheumatoid arthritis – Reuters (free)

Case-control study suggests bricklayers, concrete workers, electricians and nurses are at increased risk.

 


SGLT2 agents may reduce cardiovascular risk in diabetics

16 Aug, 2017 | 12:52h | UTC

Cardiovascular mortality and morbidity in patients with type 2 diabetes following initiation of sodium-glucose co-transporter-2 inhibitors versus other glucose-lowering drugs (CVD-REAL Nordic): a multinational observational analysis – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

Related article: Lower Risk of Heart Failure and Death in Patients Initiated on SGLT-2 Inhibitors Versus Other Glucose-Lowering Drugs: The CVD-REAL Study – Circulation (free PDF)

Commentary: SGLT2 Agents Cut CV Events in ‘Real-World’ Analysis – MedPage Today (free registration required) AND Cardiovascular disease and mortality appear lower in patients on SGLT2 inhibitors – ACP Diabetes (free)

Another observational study suggests this class of drugs may reduce cardiovascular mortality and morbidity in patients with diabeties.

 


FDA Safety Alert: Liquid-filled Intragastric Balloon Systems

16 Aug, 2017 | 13:46h | UTC

FDA Safety Alert: Liquid-filled Intragastric Balloon Systems: Letter to Healthcare Providers – Potential Risks (free)

Commentaries: Five People Die After Using Weight Loss Balloons for Obesity – Time (free) AND FDA Warns of Gastric Balloon Deaths – MedPage Today (free registration required) AND Five Deaths Tied to Intragastric Balloons, FDA Says – Medscape (free registration required)

 


Foot care for people with diabetes: prevention of complications and treatment

15 Aug, 2017 | 21:24h | UTC

Foot care for people with diabetes: prevention of complications and treatment – Evidently Cochrane Blog (free)

Related guideline: Diabetic foot problems: prevention and management – National Institute for Health and Care Excellence (free)

 


Special issue: 60 years of metformin use

16 Aug, 2017 | 13:11h | UTC

Special issue: 60 years of metformin use – Diabetologia (Source: ACP Diabetes Monthly)

– Editorial: 60 years of metformin use: a glance at the past and a look to the future (free)

– Metformin: historical overview (free)

– The mechanisms of action of metformin (free)

– Metformin: clinical use in type 2 diabetes (free)

– A new perspective on metformin therapy in type 1 diabetes (free)

– Metformin for diabetes prevention: insights gained from the Diabetes Prevention Program/Diabetes Prevention Program Outcomes Study (free)

– Metformin use in pregnancy: promises and uncertainties (free)

– Impact of metformin on cardiovascular disease: a meta-analysis of randomised trials among people with type 2 diabetes (free)

– Metformin and ageing: improving ageing outcomes beyond glycaemic control (free)

– Repurposing metformin for the prevention of cancer and cancer recurrence (free)

– The pharmacogenetics of metformin (free)

– Metformin therapy for the reproductive and metabolic consequences of polycystic ovary syndrome (free)

– The effects of metformin on gut microbiota and the immune system as research frontiers (free)

 


Wed, August 16 – 10 Stories of The Day!

16 Aug, 2017 | 00:10h | UTC

 

1 – The Effects of Cannabis Among Adults With Chronic Pain and an Overview of General Harms: A Systematic Review – Annals of Internal Medicine (free)

Related article: Benefits and Harms of Plant-Based Cannabis for Posttraumatic Stress Disorder: A Systematic Review – Annals of Internal Medicine (free)

Commentaries: Evidence on cannabis for chronic pain and PTSD – American College of Physician’s, via EurekAlert (free) AND Evidence Lacking on Benefits of Cannabis for Treating Chronic Pain, PTSD – Physician’s First Watch (free) AND Limited evidence available to determine effectiveness and safety of cannabis to treat chronic pain – 2 Minute Medicine (free) AND Little evidence that marijuana helps chronic pain, PTSD, studies find – CNN (free text and video)

 

2 – Blood pressure targets for hypertension in older adults – Cochrane Library (free)

Full review: Blood pressure targets for hypertension in older adults – Cochrane Library (link to abstract – $ for full-text)

Related guideline: Pharmacologic Treatment of Hypertension in Adults Aged 60 Years or Older to Higher Versus Lower Blood Pressure Targets: A Clinical Practice Guideline From ACP and AAFP (free)

“At the present time there is insufficient evidence to know whether a higher BP target (less than150 to 160/95 to 105 mmHg) or a lower BP target (less than 140/90 mmHg) is better for older adults with high BP”

 

3 – Analysis of Plasma Epstein–Barr Virus DNA to Screen for Nasopharyngeal Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

Quick Take Video Summary: EBV DNA Screening for Nasopharyngeal Carcinoma (free)

Commentaries: Can a ‘liquid biopsy’ detect cancer and save lives? – STAT (free) AND Liquid Biopsy Passes Test for Nasopharyngeal Cancer – MedPage Today (free registration required) AND Early Detection of Nasopharyngeal Cancer With EBV DNA – Medscape (free registration required) AND Plasma Epstein–Barr virus DNA useful for nasopharyngeal carcinoma screening – 2 Minute Medicine (free)

 

4 – Association of Previous Cesarean Delivery With Surgical Complications After a Hysterectomy Later in Life – JAMA Surgery (free)

Commentaries: C-Section Delivery Associated with Increased Risk of Complications from Hysterectomy – The JAMA Network (free) AND C-Section Now, Hysterectomy Complications Later? – MedPage Today (free registration required)

 

5 – Risk of head and traumatic brain injuries associated with antidepressant use among community-dwelling persons with Alzheimer’s disease: a nationwide matched cohort study – Alzheimer’s Research & Therapy (free)

Commentary: Antidepressant use increases risk of head injuries among persons with Alzheimer’s disease – University of Eastern Finland, via EurekAlert (free)

 

6 – Cholera count reaches 500 000 in Yemen – World Health Organization (free)

Commentaries: Yemen’s cholera outbreak passes 500,000 cases – CIDRAP (free) AND More Than 500,000 Infected With Cholera in Yemen – The New York Times (10 articles per month are free)

 

7 – Surgery must be a core part of health care – even in the poorest countries – The Guardian (free)

Related book: Essential Surgery – Disease Control Priorities 3 (DCP3) (free)

Related report: Global Surgery 2030 (free PDF)

Related commentary on the subject: In countries with a shortage of surgeons, other health care workers can fill in the gaps – STAT (free)

 

8 – Dexamethasone before bowel surgery reduces postoperative nausea and vomiting – NIHR Signal (free)

Original article: Dexamethasone versus standard treatment for postoperative nausea and vomiting in gastrointestinal surgery: randomised controlled trial (DREAMS Trial) – The BMJ (free)

 

9 – Relationship of Alcohol Consumption to All-Cause, Cardiovascular, and Cancer-Related Mortality in U.S. Adults – Journal of The American College of Cardiology (link to abstract and infographic – $ for full-text)

Commentaries: Consuming Alcohol in Moderation Can Lower Mortality Risks – American College of Cardiology, Latest in Cardiology (free) AND Alcohol Consumption and All-Cause, CV, and Cancer-Related Mortality – American College of Cardiology, Latest in Cardiology (free) AND Can drinking a little bit help you live longer? – Reuters (free)

 

10 – Addressing Alcohol Use Practice Manual: An Alcohol Screening and Brief Intervention Program – American Academy of Family Physicians (free PDF)

Press release: AAFP, Baylor Partner to Create Alcohol Screening Practice Manual (free)

Commentary: Alcohol screening and brief intervention: A practice manual for clinicians – Clinical Advisor (free)

 


3 reasons why you should be suspicious of study ‘subgroup’ results

15 Aug, 2017 | 21:10h | UTC

3 reasons why you should be suspicious of study ‘subgroup’ results – HealthNewsReview (free)

 


The Effects of Cannabis Among Adults With Chronic Pain

15 Aug, 2017 | 22:25h | UTC

The Effects of Cannabis Among Adults With Chronic Pain and an Overview of General Harms: A Systematic Review – Annals of Internal Medicine (free)

Related article: Benefits and Harms of Plant-Based Cannabis for Posttraumatic Stress Disorder: A Systematic Review – Annals of Internal Medicine (free)

Commentaries: Evidence on cannabis for chronic pain and PTSD – American College of Physician’s, via EurekAlert (free) AND Evidence Lacking on Benefits of Cannabis for Treating Chronic Pain, PTSD – Physician’s First Watch (free) AND Limited evidence available to determine effectiveness and safety of cannabis to treat chronic pain – 2 Minute Medicine (free) AND Little evidence that marijuana helps chronic pain, PTSD, studies find – CNN (free text and video)

 


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